Accessibility navigation

Asymmetric synthesis of arylalanines via asymmetric aza-darzens (ADZ) reaction

Lists
Tools

Maguire, N.E., McLaren, A.B. and Sweeney, J.B. (2003) Asymmetric synthesis of arylalanines via asymmetric aza-darzens (ADZ) reaction. Synlett, 12. pp. 1898-1900. ISSN 0936-5214

Full text not archived in this repository.

It is advisable to refer to the publisher's version if you intend to cite from this work. See Guidance on citing.

To link to this item DOI: 10.1055/s-2003-41470

Abstract/Summary

(R)-3-Arylalanines may be prepared in high enantiomeric purity from N-dpp imines by a four-step reaction sequence involving asymmetric aza-Darzens reaction, dephosphinylation, hydrogenolysis and hydrolysis. The amino acids thus obtained were of >95% enantiomeric purity.

Item Type:Article
Refereed:Yes
Divisions:Life Sciences > School of Chemistry, Food and Pharmacy > Department of Chemistry
ID Code:11449
Uncontrolled Keywords:aziridine, dpp, hydrogenolysis, (R)-amino acid , AMINO-ACID-DERIVATIVES, DYNAMIC KINETIC RESOLUTION, ENANTIOSELECTIVE SYNTHESIS, AZIRIDINE SYNTHESIS, ESTERS, CATALYST, REDUCTION, ALDEHYDES, ENOLATE, KETONES
Altmetric
Deposit Details

University Staff: Request a correction | Centaur Editors: Update this record

Page navigation

See also