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Towards the total synthesis of colletofragarones: constructing the macrocyclic lactone by high pressure-mediated intramolecular Diels-Alder reaction

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Marrero, J.G. and Harwood, L.M. ORCID: https://orcid.org/0000-0002-8442-7380 (2009) Towards the total synthesis of colletofragarones: constructing the macrocyclic lactone by high pressure-mediated intramolecular Diels-Alder reaction. Tetrahedron Letters, 50 (26). pp. 3574-3576. ISSN 0040-4039

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To link to this item DOI: 10.1016/j.tetlet.2009.03.063

Abstract/Summary

We report herein an intramolecular Diels-Alder approach towards the construction of the macrocyclic lactone ring and the perhydrobenzofuran system of the colletofragarones, novel metabolites produced by fungi of the genus Colletotrichum that are responsible for inhibition of germination of the conidia in these species. Crown Copyright (C) 2009 Published by Elsevier Ltd. All rights reserved.

Item Type:Article
Refereed:Yes
Divisions:Life Sciences > School of Chemistry, Food and Pharmacy > Department of Chemistry
Interdisciplinary centres and themes > Chemical Analysis Facility (CAF)
ID Code:11462
Uncontrolled Keywords:COLLETOTRICHUM-FRAGARIAE, ACID, INHIBITORS
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