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Analyzing diffusion tensor images with ghosting artifacts: the effects of direct and indirect normalization

Shen, S. and Sterr, A. (2010) Analyzing diffusion tensor images with ghosting artifacts: the effects of direct and indirect normalization. Magnetic Resonance Imaging, 28 (10). pp. 1507-1513. ISSN 0730-725X

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To link to this article DOI: 10.1016/j.mri.2010.06.010

Abstract/Summary

The current study aims to assess the applicability of direct or indirect normalization for the analysis of fractional anisotropy (FA) maps in the context of diffusion-weighted images (DWIs) contaminated by ghosting artifacts. We found that FA maps acquired by direct normalization showed generally higher anisotropy than indirect normalization, and the disparities were aggravated by the presence of ghosting artifacts in DWIs. The voxel-wise statistical comparisons demonstrated that indirect normalization reduced the influence of artifacts and enhanced the sensitivity of detecting anisotropy differences between groups. This suggested that images contaminated with ghosting artifacts can be sensibly analyzed using indirect normalization.

Item Type:Article
Refereed:Yes
Divisions:Interdisciplinary centres and themes > Centre for Integrative Neuroscience and Neurodynamics (CINN)
ID Code:16020
Publisher:Elsevier

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