Accessibility navigation


Platelets stop us leaking

Gibbins, J. M. (2016) Platelets stop us leaking. Blood, 127 (12). pp. 1528-1529. ISSN 0006-4971

[img]
Preview
Text - Accepted Version
· Please see our End User Agreement before downloading.

102kB
[img] Image - Supplemental Material
· Please see our End User Agreement before downloading.

71kB

It is advisable to refer to the publisher's version if you intend to cite from this work. See Guidance on citing.

To link to this item DOI: 10.1182/blood-2016-01-692186

Abstract/Summary

In this issue of Blood, Welsh and colleagues determine how platelet thrombi limit the loss of plasma-borne proteins from the microvasculature. 1 The concept that platelets prevent leakage from blood vessels following a penetrating injury will come as little surprise to most readers, but exactly how platelets physically contribute to this process is not well understood. Such injuries result in the loss of blood cells and plasma into the surrounding tissues, and both forms of loss must be halted quickly. Platelets are believed to form the first line of defense in such situations, forming a thrombus that is capable of plugging the hole and supplying molecules that contribute to localized inflammation and wound healing.

Item Type:Article
Refereed:Yes
Divisions:Interdisciplinary centres and themes > Institute for Cardiovascular and Metabolic Research (ICMR)
Faculty of Life Sciences > School of Biological Sciences > Biomedical Sciences
ID Code:67337
Uncontrolled Keywords:platelets, thrombosis, haemostasis, thrombi
Publisher:American Society of Hematology

Downloads

Downloads per month over past year

University Staff: Request a correction | Centaur Editors: Update this record

Page navigation