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Effect of simulated gastrointestinal digestion and fermentation on polyphenolic content and bioactivity of brown seaweed phlorotannin-rich extracts

Corona, G., Coman, M. M., Guo, Y., Hotchkiss, S., Gill, C., Yaqoob, P., Spencer, J. P. E. and Rowland, I. (2017) Effect of simulated gastrointestinal digestion and fermentation on polyphenolic content and bioactivity of brown seaweed phlorotannin-rich extracts. Molecular Nutrition and Food Research, 61 (11). 1700223. ISSN 1613-4133

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To link to this item DOI: 10.1002/mnfr.201700223

Abstract/Summary

Although phlorotannins, TP levels and antioxidant power of the extracts were strongly reduced after in vitro digestion and fermentation, their anti-genotoxic activity and cell growth inhibitory effect in colon HT-29 cells was maintained and enhanced. HMW was the most effective fraction, indicating that the high molecular weight phlorotannins potentially exert a stronger beneficial effect in the colon.

Item Type:Article
Refereed:Yes
Divisions:Faculty of Life Sciences > School of Chemistry, Food and Pharmacy > Department of Food and Nutritional Sciences > Human Nutrition Research Group
ID Code:71528
Publisher:Wiley

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