Article

Caló, E. and Khutoryanskiy, V. V. (2014) Biomedical applications of hydrogels: a review of patents and commercial products. European Polymer Journal. ISSN 0014-3057 doi: 10.1016/j.eurpolymj.2014.11.024 (In Press)

Morrison, P. and Khutoryanskiy, V. (2014) Enhancement in corneal permeability of riboflavin using calcium sequestering compounds. International Journal of Pharmaceutics, 472 (1-2). pp. 56-64. ISSN 0378-5173 doi: 10.1016/j.ijpharm.2014.06.007

Mun, E. A., Morrison, P. W. J., Williams, A. C. and Khutoryanskiy, V. V. (2014) On the barrier properties of the cornea: a microscopy study of the penetration of fluorescently labeled nanoparticles, polymers, and sodium fluorescein. Molecular Pharmaceutics, 11 (10). pp. 3556-3564. ISSN 1543-8392 doi: 10.1021/mp500332m

Bizley, S. C., Williams, A. C. and Khutoryanskiy, V. V. (2014) Thermodynamic and kinetic properties of interpolymer complexes assessed by isothermal titration calorimetry and surface plasmon resonance. Soft Matter, 10. pp. 8254-8260. ISSN 1744-683X doi: 10.1039/C4SM01138D

Cook, M., Tzortzis, G., Charalampopoulos, D. and Khutoryanskiy, V. (2014) Microencapsulation of a synbiotic into PLGA/alginate multiparticulate gels. International Journal of Pharmaceutics, 466 (1-2). pp. 400-408. ISSN 0378-5173 doi: 10.1016/j.ijpharm.2014.03.034

Morrison, P. W. J. and Khutoryanskiy, V. V. (2014) Advances in ophthalmic drug delivery. Therapeutic Delivery, 5 (12). pp. 1297-1315. ISSN 2041-5990 doi: 10.4155/tde.14.75

Khutoryanskaya, O., Morrison, P., Seilkhanov, S., Mussin, M. , Ozhmukhametova, E. , Rakhypbekov, T. and Khutoryanskiy, V. (2014) Hydrogen-bonded complexes and blends of poly(acrylic acid) and methylcellulose: nanoparticles and mucoadhesive films for Ocular Delivery of Riboflavin. Macromolecular Bioscience, 14 (2). pp. 225-234. ISSN 1616-5187 doi: 10.1002/mabi.201300313

Mun, E. A., Hannell, C., Rogers, S. E., Hole, P. , Williams, A. C. and Khutoryanskiy, V. V. (2014) On the role of specific interactions in the diffusion of nanoparticles in aqueous polymer solutions. Langmuir, 30 (1). pp. 308-317. ISSN 0743-7463 doi: 10.1021/la4029035

Baygazieva, E. K., Yesmurzayeva, N. N., Tatykhanova, G. S., Mun, G. A., Khutoryanskiy, V. V. and Kudaibergenov, S. E. (2014) Polymer protected gold nanoparticles: synthesis, characterization and application in catalysis. International Journal of Biology and Chemistry, 7 (1). pp. 14-23.

de Barros, J. M. S., Scherer, T., Charalampopoulos, D., Khutoryanskiy, V. V. and Edwards, A. D. (2014) A laminated polymer film formulation for enteric delivery of live vaccine and probiotic bacteria. Journal of Pharmaceutical Sciences, 103 (7). pp. 2022-2032. ISSN 1520-6017 doi: 10.1002/jps.23997

Driver, K., Baco, S. and Khutoryanskiy, V. (2013) Hollow capsules formed in a single stage via interfacial hydrogen-bonded complexation of methylcellulose with poly(acrylic acid) and tannic acid. European Polymer Journal, 49 (12). pp. 4249-4256. ISSN 0014-3057 doi: 10.1016/j.eurpolymj.2013.10.004

Withers, C. A., Cook, M. T., Methven, L., Gosney, M. A. and Khutoryanskiy, V. V. (2013) Investigation of milk proteins binding to the oral mucosa. Food & Function. ISSN 2042-650X doi: 10.1039/c3fo60291e

Aravindan, L., Bicknell, K.A., Brooks, G., Khutoryanskiy, V.V. and Williams, A.C. (2013) A comparison of thiolated and disulfide‐crosslinked polyethylenimine for nonviral gene delivery. Macromolecular Bioscience, 13 (9). pp. 1163-1173. ISSN 1616-5187 doi: 10.1002/mabi.201300103

Cook, M. T., Saratoon, T., Tzortzis, G., Edwards, A., Charalampopoulos, D. and Khutoryanskiy, V. V. (2013) CLSM method for the dynamic observation of pH change within polymer matrices for oral delivery. Biomacromolecules, 14 (2). pp. 387-393. ISSN 1525-7797 doi: 10.1021/bm301569r

Morrison, P. W.J., Connon, C. J. and Khutoryanskiy, V. V. (2013) Cyclodextrin-mediated enhancement of riboflavin solubility and corneal permeability. Molecular Pharmaceutics, 10 (2). pp. 756-762. ISSN 1543-8392 doi: 10.1021/mp3005963

Cook, M., Tzortzis, G. T., Khutoryanskiy, V. V. and Charalampopoulos, D. (2013) Layer-by-layer coating of alginate matrices with chitosan–alginate for the improved survival and targeted delivery of probiotic bacteria after oral administration. Journal of Materials Chemistry B, 1. pp. 52-60. doi: 10.1039/C2TB00126H

Storha, A., Mun, E. A. and Khutoryanskiy, V. (2013) Synthesis of thiolated and acrylated nanoparticles using thiol-ene click chemistry: towards novel mucoadhesive materials for drug delivery. RSC Advances, 3 (30). pp. 12275-12279. ISSN 2046-2069 doi: 10.1039/C3RA42093K

Sogias, I., Williams, A. and Khutoryanskiy, V. (2012) Chitosan-based mucoadhesive tablets for oral delivery of ibuprofen. International Journal of Pharmaceutics, 436 (1-2). pp. 602-610. ISSN 0378-5173 doi: 10.1016/j.ijpharm.2012.07.007

Cook, M. T., Tzortzis, G., Charalampopoulos, D. and Khutoryanskiy, V. V. (2012) Microencapsulation of probiotics for gastrointestinal delivery. Journal of Controlled Release, 162 (1). pp. 56-67. ISSN 0168-3659 doi: 10.1016/j.jconrel.2012.06.003

Kudaibergenov, S. E., Nuraje, N. and Khutoryanskiy, V. (2012) Amphoteric nano-, micro-, and macrogels, membranes, and thin films. Soft Matter, 8 (36). pp. 9302-9321. ISSN 1744-683X doi: 10.1039/C2SM25766A

Bizley, S. C., Williams, A. C., Kemp, F. and Khutoryanskiy, V. V. (2012) Optimizing layer-by-layer deposition of interpolymer complexes on solid substrates using Biacore. Soft Matter, 8 (25). pp. 2782-2787. ISSN 1744-683X doi: 10.1039/C2SM25652E

Wright, B., Cave, R. A., Cook, J. P., Khutoryanskiy, V. V., Mi, S., Chen, B., Leyland, M. and Connon, C. J. (2012) Enhanced viability of corneal epithelial cells for efficient transport/storage using a structurally-modified calcium alginate hydrogel. Regenerative Medicine, 7 (3). pp. 295-307. ISSN 1746-076X doi: 10.2217/rme.12.7

Cave, R., Cook, J., Connon, C. J. and Khutoryanskiy, V. V. (2012) A flow system for the on-line quantitative measurement of the retention of dosage forms on biological surfaces using spectroscopy and image analysis. International Journal of Pharmaceutics, 428 (1-2). pp. 96-102. ISSN 0378-5173 doi: 10.1016/j.ijpharm.2012.02.047

Cook, J., Goodall, G. W., Khutoryanskaya, O. and Khutoryanskiy, V. V. (2012) Microwave-assisted hydrogel synthesis: a new method for crosslinking polymers in aqueous solutions. Macromolecular Rapid Communications, 33 (4). pp. 332-336. ISSN 1022-1336 doi: 10.1002/marc.201100742

Nualkaekul, S., Lenton, D., Cook, M. T., Khutoryanskiy, V. and Charalampopoulos, D. (2012) Chitosan coated alginate beads for the survival of microencapsulated Lactobacillus plantarum in pomegranate juice. Carbohydrate Polymers, 90 (3). pp. 1281-1287. ISSN 0144-8617 doi: 10.1016/j.carbpol.2012.06.073

Irmukhametova, G., Fraser, B., Keddie, J., Mun, G. and Khutoryanskiy, V. V. (2012) Hydrogen-bonding-driven self-assembly of PEGylated organosilica nanoparticles with poly(acrylic acid) in aqueous solutions and in layer-by-layer deposition at solid surfaces. Langmuir, 28 (1). pp. 299-306. ISSN 0743-7463 doi: 10.1021/la2038735

Mi, S., Khutoryanskiy, V. V., Jones, R. R., Zhu, X., Hamley, I. W. and Connon, C. J. (2011) Photochemical cross-linking of plastically compressed collagen gel produces an optimal scaffold for corneal tissue engineering. Journal of Biomedical Materials Research Part A, 99A (1). pp. 1-8. ISSN 1549-3296 doi: 10.1002/jbm.a.33152

Irmukhametova, G. S., Mun, G. A. and Khutoryanskiy, V. V. (2011) Thiolated mucoadhesive and PEGylated nonmucoadhesive organosilica nanoparticles from 3-Mercaptopropyltrimethoxysilane. Langmuir, 27 (15). pp. 9551-9556. ISSN 1520-5827 doi: 10.1021/la201385h

Hall, D. J., Khutoryanskaya, O. V. and Khutoryanskiy, V. V. (2011) Developing synthetic mucosa-mimetic hydrogels to replace animal experimentation in characterisation of mucoadhesive drug delivery systems. Soft Matter, 7 (20). pp. 9620-9623. ISSN 1744-683X doi: 10.1039/C1SM05929G

Cook, M. T., Tzortzis, G., Charalampopoulos, D. and Khutoryanskiy, V. V. (2011) Production and evaluation of dry alginate-chitosan microcapsules as an enteric delivery vehicle for probiotic bacteria. Biomacromolecules, 12 (7). pp. 2834-2840. ISSN 1525-7797 doi: 10.1021/bm200576h

Khutoryanskiy, V. V. (2011) Advances in mucoadhesion and mucoadhesive polymers. Macromolecular Bioscience, 11 (6). pp. 748-764. ISSN 1616-5187 doi: 10.1002/mabi.201000388

Zhunuspayev, D., Mun, G. and Khutoryanskiy, V. V. (2010) Temperature-responsive properties and drug solubilization capacity of amphiphilic copolymers based on N-vinylpyrrolidone and vinyl propyl ether. Langmuir, 26 (10). pp. 7590-7597. ISSN 1520-5827 doi: 10.1021/la904403k

Sogias, I., Khutoryanskiy, V. V. and Williams, A. C. (2010) Exploring the Factors Affecting the Solubility of Chitosan in Water. Macromolecular Chemistry and Physics, 211 (4). pp. 426-433. ISSN 1022-1352 doi: 10.1002/macp.200900385

Khutoryanskaya, O., Potgieter, M. and Khutoryanskiy, V. V. (2010) Multilayered hydrogel coatings covalently-linked to glass surfaces showing a potential to mimic mucosal tissues. Soft Matter, 6. pp. 551-556. ISSN 1744-683X doi: DOI:10.1039/b918007a

Aravindan, L. , Bicknell, K. A., Brooks, G., Khutoryanskiy, V. V. and Williams, A. C. (2009) Effect of acyl chain length on transfection efficiency and toxicity of polyethylenimine. International Journal of Pharmaceutics, 378 (1-2). pp. 201-210. ISSN 0378-5173 doi: 10.1016/j.ijpharm.2009.05.052

Al-Saadi , A., Yu , C.H., Khutoryanskiy, V. V., Shih , S.-J., Crossley , A. and Tsang , S.C. (2009) Layer-by-layer electrostatic entrapment of protein molecules on superparamagnetic nanoparticle: new strategy to enhance adsorption capacity and maintain biological activity. Journal of Physical Chemistry C, 113 (34). pp. 15260-15265. ISSN 1932-7447 doi: DOI:10.1021/jp903100j

Khutoryanskiy, V. V. and Khutoryanskaya, O. (2009) A basic guide to hydrogels. Newsletter of the United Kingdom and Ireland Controlled Release Society , 14. pp. 26-30.

Khutoryanskaya, O., Mayeva, Z., Mun, G. and Khutoryanskiy, V. V. (2008) Designing Temperature-Responsive Biocompatible Copolymers and Hydrogels Based on 2-Hydroxyethyl(meth)acrylates. Biomacromolecules, 9 (12). pp. 3353-3361. ISSN 1525-7797 doi: 10.1021/bm8006242

Zhunuspayev, D., Mun, G., Hole, P. and Khutoryanskiy, V. V. (2008) Solvent Effects on the Formation of Nanoparticles and Multilayered Coatings Based on Hydrogen-Bonded Interpolymer Complexes of Poly(acrylic acid) with Homo- and Copolymers of N-Vinyl Pyrrolidone. Langmuir, 24 (23). pp. 13742-13747. ISSN 0743-7463 doi: DOI:10.1021/la802852h

Sogias, I., Williams, A. C. and Khutoryanskiy, V. V. (2008) Why is Chitosan Mucoadhesive? Biomacromolecules, 9 (7). pp. 1837-1842. ISSN 1525-7797 doi: 10.1021/bm800276d

Luo, K., Yin, J.B., Khutoryanskaya, O.V. and Khutoryanskiy, V.V. (2008) Mucoadhesive and elastic films based on blends of chitosan and hydroxyethylcellulose. Macromolecular Bioscience, 8 (2). pp. 184-192. ISSN 1616-5187 doi: 10.1002/mabi.200700185

Khutoryanskiy, V.V. (2007) Hydrogen-bonded interpolymer complexes as materials for pharmaceutical applications. International Journal of Pharmaceutics, 334 (1-2). pp. 15-26. ISSN 0378-5173 doi: 10.1016/j.ijpharm.2007.01.037

Fefelova, N.A., Nurkeeva, Z.S., Mun, G.A. and Khutoryanskiy, V.V. (2007) Mucoadhesive interactions of amphiphilic cationic copolymers based on [2-(methacryloyloxy)ethyl]trimethylammonium chloride. International Journal of Pharmaceutics, 339 (1-2). pp. 25-32. ISSN 0378-5173 doi: 10.1016/j.ijpharm.2007.02.019

Aal, A.A., Khutoryanskiy, V.V., Nurkeeva, Z.S. and Mun, G.A. (2007) Optimization of electroless copper plating on polyethylene films modified by surface grafting of vinyl ether of monoethanolamine. Eurasian Chemico-Technological Journal, 9 (1). pp. 63-70. ISSN 1562-3920

Khutoryanskiy, V.V. and Tirelli, N. (2007) Oxidation-responsiveness of nanomaterials for targeting inflammatory reactions. Pure and Applied Chemistry, 80 (8). pp. 1703-1718. ISSN 0033-4545 doi: 10.1351/pac200880081703

Mun, G.A., Nurkeeva, Z.S., Beissegul, A.B., Dubolazov, A.V., Urkimbaeva, P.I., Park, K. and Khutoryanskiy, V.V. (2007) Temperature-responsive water-soluble copolymers based on 2-hydroxyethyl acrylate and butyl acrylate. Macromolecular Chemistry and Physics, 208 (9). pp. 979-987. ISSN 1022-1352 doi: 10.1002/macp.200600555

Khutoryanskaya, O.V., Williams, A.C. and Khutoryanskiy, V.V. (2007) pH-mediated interactions between poly(acrylic acid) and methylcellulose in the formation of ultrathin multilayered hydrogels and spherical nanoparticles. Macromolecules, 40 (21). pp. 7707-7713. ISSN 0024-9297 doi: 10.1021/ma071644v

Qu, X.Z., Khutoryanskiy, V.V., Stewart, A., Rahman, S., Papahadjopoulos-Sternberg, B., Dufes, C., McCarthy, D., Wilson, C.G., Lyons, R., Carter, K.C., Schatzlein, A. and Uchegbu, I.F. (2006) Carbohydrate-based micelle clusters which enhance hydrophobic drug bioavailability by up to 1 order of magnitude. Biomacromolecules, 7 (12). pp. 3452-3459. ISSN 1525-7797 doi: 10.1021/bm0604000

Dubolazov, A.V., Nurkeeva, Z.S., Mun, G.A. and Khutoryanskiy, V.V. (2006) Design of mucoadhesive polymeric films based on blends of poly(acrylic acid) and (hydroxypropyl)cellulose. Biomacromolecules, 7 (5). pp. 1637-1643. ISSN 1525-7797 doi: 10.1021/bm060090l

Mangazbaeva, R.A., Mun, G.A., Nurkeeva, Z.S. and Khutoryanskiy, V.V. (2006) Interpolymer complexes of hydroxy-propylmethylcellulose with polycarboxylic acids in aqueous solutions. Polymer International, 55 (6). pp. 668-674. ISSN 0959-8103 doi: 10.1002/pi.2012

Yin, J. B., Luo, K., Chen, X. S. and Khutoryanskiy, V. V. (2006) Miscibility studies of the blends of chitosan with some cellulose ethers. Carbohydrate Polymers, 63 (2). pp. 238-244. ISSN 0144-8617 doi: 10.1016/j.carbpol.2005.08.041

Mun, G.A., Nurkeeva, Z.S., Akhmetkalieva, G.T., Shmakov, S.N., Khutoryanskiy, V.V., Lee, S.C. and Park, K. (2006) Novel temperature-responsive water-soluble copolymers based on 2-hydroxyethylacrylate and vinyl butyl ether and their interactions with poly(carboxylic acids). Journal of Polymer Science Part B-Polymer Physics, 44 (1). pp. 195-204. ISSN 0887-6266 doi: 10.1002/polb.20695

Nurkeeva, Z.S., Mun, G.A., Sergaziev, A.D., Fefelova, N.A., Sarsenbaeva, A.S. and Khutoryanskiy, V.V. (2006) Synthesis of cationic water-soluble copolymers and hydrogels based on [2-(methacryloyloxy)ethyl]trimethylammonium cloride and 2-hydroxyethylacrylate and their complex formation with poly(acrylic acid). Journal of Polymer Science Part B-Polymer Physics, 44 (5). pp. 845-853. ISSN 0887-6266 doi: 10.1002/polb.20742

Khutoryanskaya, O.V., Khutoryanskiy, V.V. and Pethrick, R.A. (2005) Characterisation of blends based on hydroxyethylcellulose and maleic acid-alt-methyl vinyl ether. Macromolecular Chemistry and Physics, 206 (15). pp. 1497-1510. ISSN 1022-1352 doi: 10.1002/macp.200500069

Nurkeeva, Z.S., Tyukova, I.S., Suvorova, A.I., Mun, G.A., Dzhusupbekova, A.B. and Khutoryanskiy, V.V. (2005) Miscibility studies in poly(methyl vinyl ether)/hydroxypropylcellulose binary system in aqueous solutions and solid state. Carbohydrate Polymers, 62 (1). pp. 80-86. ISSN 0144-8617 doi: 10.1016/j.carbpol.2005.06.023

Nurkeeva, Z.S., Mun, G.A., Dubolazov, A.V. and Khutoryanskiy, V.V. (2005) pH effects on the complexation, miscibility and radiation-induced crosslinking in poly(acrylic acid)-poly (vinyl alcohol) blends. Macromolecular Bioscience, 5 (5). pp. 424-432. ISSN 1616-5187 doi: 10.1002/mabi.200400200

Book or Report Section

Cook, M. T., Charalampopoulos, D. and Khutoryanskiy, V. V. (2014) Microencapsulation of probiotic bacteria into alginate hydrogels. In: Connon, C. J. and Hamley, I. W. (eds.) Hydrogels in Cell-Based Therapies. RSC soft matter series. Royal Society of Chemistry, Cambridge, pp. 95-111. ISBN 9781782621263

Khutoryanskiy, V. V. and Khutoryanskaya, O. (2009) Design and evaluation of hydrogel films based on polymeric blends. In: Stein, D. (ed.) Handbook of Hydrogels: Properties, Preparation and Applications. Chemical Engineering Methods and Technology. Nova Science Publishers, Inc., Hauppauge NY USA, pp. 521-540. ISBN 9781607417026

Khutoryanskiy, V.V. (2009) Pharmaceutical applications of interpolymer complexes. In: Khutoryanskiy, V.V. and Staikos, G. (eds.) Hydrogen-bonded interpolymer complexes: formation, structure and applications. World Scientific, Singapore, pp. 235-258. ISBN 9789812707857

Khutoryanskiy, V.V., Dubolazov, A.V. and Mun, G.A. (2009) pH- and ionic strength effects on interpolymer complexation via hydrogen-bonding. In: Khutoryanskiy, V.V. and Staikos, G. (eds.) Hydrogen-bonded interpolymer complexes: formation, structure and applications. World Scientific, Singapore, pp. 1-22. ISBN 9789812707857

Conference or Workshop Item

Khutoryanskiy, V. V. (2011) Application of interpolymer complexation to coat solid and soft surfaces. In: 38th Annual Waterborne Symposium, 28 February - 4 March 2011, New Orleans, USA, pp. 212-218. (In Press)

Book

Khutoryanskiy, V., ed. (2014) Mucoadhesive materials and drug delivery systems. Wiley, Chichester, pp352. ISBN 9781119941439