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Items where Author is "Whalley, Professor Ben"

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Article

Iannotti, F. A., Hill, C. L., Leo, A., Alhusaini, A., Soubrane, C. , Mazzarella, E. , Russo, E. , Whalley, B. J., Di Marzo, V. and Stephens, G. J. (2014) Nonpsychotropic plant cannabinoids, cannabidivarin (CBDV) and cannabidiol (CBD), activate and desensitize transient receptor potential vanilloid 1 (TRPV1) channels in vitro: potential for the treatment of neuronal hyperexcitability. ACS Chemical Neuroscience. ISSN 1948-7193 doi: 10.1021/cn5000524

Hill, A., Jones, N., Smith, I., Hill, C., Williams, C., Stephens, G. and Whalley, B. (2014) Voltage-gated sodium (NaV) channel blockade by plant cannabinoids does not confer anticonvulsant effects per se. Neuroscience Letters, 566. pp. 269-274. ISSN 0304-3940 doi: 10.1016/j.neulet.2014.03.013

Smith, I., Williamson, E. M., Putnam, S., Farrimond, J. and Whalley, B. J. (2014) Effects and mechanisms of ginseng and ginsenosides on cognition. Nutrition Reviews. ISSN 1753-4887 doi: 10.1111/nure.12099 (In Press)

Wang, X. , Whalley, B. J. and Stephens, G. J. (2013) The du2J mouse model of ataxia and absence epilepsy has deficient cannabinoid CB1 receptor-mediated signalling. Journal of Physiology, 591 (16). pp. 3919-3933. ISSN 1469-7793 doi: 10.1113/jphysiol.2012.244947

Amada, N., Yamasaki, Y., Williams, C. and Whalley, B. (2013) Cannabidivarin (CBDV) suppresses pentylenetetrazole (PTZ)-induced increases in epilepsy-related gene expression. PeerJ. 1:e214. ISSN 2167-8359 doi: 10.7717/peerj.214

Hill, T., Cascio, M., Romano, B., Duncan, M., Pertwee, R., Williams, C., Whalley, B. and Hill, A. (2013) Cannabidivarin-rich cannabis extracts are anticonvulsant in mouse and rat via a CB 1 receptor-independent mechanism. British Journal of Pharmacology, 170 (3). pp. 679-692. ISSN 1476-5381 doi: 10.1111/bph.12321

Hoppe, J. B., Haag, M., Whalley, B. J., Salbego, C. G. and Cimarosti, H. (2013) Curcumin protects organotypic hippocampal slice cultures 4 from Ab1–42 -induced synaptic toxicity. Toxicology in Vitro, 27 (8). pp. 2325-2330. ISSN 1879-3177 doi: 10.1016/j.tiv.2013.10.002

Hammond, M. W., Xydas, D., Downes, J. H., Bucci, G., Becerra, V., Warwick, K., Constanti, A., Nasuto, S. and Whalley, B. (2013) Endogenous cholinergic tone modulates spontaneous network level neuronal activity in primary cortical cultures grown on multi-electrode arrays. BMC Neuroscience, 14. 38. ISSN 1471-2202 doi: 10.1186/1471-2202-14-38

Hill, A. J., Mercier, M. S., Hill, T. D., Glyn, S. E., Jones, N. A., Yamasaki, Y., Futamura, T., Duncan, M., Stott, C.G., Stephens, G.J., Williams, C. M. and Whalley, B.J. (2012) Cannabidivarin is anticonvulsant in mouse and rat in vitro and in seizure models. British Journal of Pharmacology, 167 (8). pp. 1629-1642. ISSN 0007-1188 doi: 10.1111/j.1476-5381.2012.02207.x

Jones, N. A., Glyn, S., Akiyama, S., Hill, T. D.M., Hill, A., Weston, S., Burnett, M. D.A., Yamasaki, Y., Stephens, G., Whalley, B. and Williams, C. (2012) Cannabidiol exerts anti-convulsant effects in animal models of temporal lobe and partial seizures. Seizure, 21 (5). pp. 344-352. ISSN 1059-1311 doi: 10.1016/j.seizure.2012.03.001

Farrimond, J. A., Whalley, B. J. and Williams, C. M. (2012) Cannabinol and cannabidiol exert opposing effects on rat feeding patterns. Psychopharmacology, 223 (1). pp. 117-129. ISSN 0033-3158 doi: 10.1007/s00213-012-2697-x

Farrimond, J. A., Whalley, B. and Williams, C. (2012) Non-D9-tetrahydrocannabinol phytocannabinoids stimulate feeding in rats. Behavioural Pharmacology, 23 (1). pp. 113-117. ISSN 0955-8810 doi: 10.1097/FBP.0b013e32834ed832

Downes, J. H., Hammond, M. W., Xydas, D., Spencer, M. C., Becerra, V. M., Warwick, K., Nasuto, S. and Whalley, B. (2012) Emergence of a small-world functional network in cultured neurons. PLoS Computational Biology, 8 (5). pp. 1-17. ISSN 1553-734X doi: 10.1371/journal.pcbi.1002522

Hill, A. J., Williams, C. M., Whalley, B. J. and Stephens, G. J. (2012) Phytocannabinoids as novel therapeutic agents in CNS disorders. Pharmacology & Therapeutics, 133 (1). pp. 79-97. ISSN 0163-7258 doi: 10.1016/j.pharmthera.2011.09.002

Vogl, C., Mochida, S., Wolff, C., Whalley, B. and Stephens, G. (2012) The SV2A ligand levetiracetam inhibits presynaptic Ca2+ channels via an intracellular pathway. Molecular Pharmacology, 82 (2). pp. 199-208. ISSN 1521-0111 doi: 10.1124/mol.111.076687

Spencer, M. C., Downes, J. H., Xydas, D., Hammond, M. W., Becerra, V. M., Warwick, K., Whalley, B. J. and Nasuto, S. J. (2011) Multiscale evolving complex network model of functional connectivity in neuronal cultures. IEEE Transactions on Biomedical Engineering, 59 (1). pp. 30-34. ISSN 0018-9294 doi: 10.1109/TBME.2011.2171340

Xydas, D., Downes, J. H., Spencer, M. C., Hammond, M. W., Nasuto, S. J., Whalley, B. J., Becerra, V. M. and Warwick, K. (2011) Revealing ensemble state transition patterns in multi-electrode neuronal recordings using hidden Markov models. IEEE Transactions on Neural Systems and Rehabilitation Engineering, 19 (4). pp. 345-355. ISSN 1534-4320 doi: 10.1109/TNSRE.2011.2157360

Wang, X., Horswill, J. G., Whalley, B. J. and Stephens, G. J. (2011) Effects of the Allosteric Antagonist 1-(4-Chlorophenyl)-3-[3-(6-pyrrolidin-1-ylpyridin-2-yl)phenyl]urea (PSNCBAM-1) on CB1 Receptor Modulation in the Cerebellum. Molecular Pharmacology, 79 (4). pp. 758-767. ISSN 1521-0111 doi: 10.1124/mol.110.068197

Farrimond, J. A., Mercier, M. S., Whalley, B. J. and Williams, C. M. (2011) Cannabis sativa and the endogenous cannabinoid system: therapeutic potential for appetite regulation. Phytotherapy Research, 25 (2). pp. 170-188. ISSN 0951-418X

Farrimond, J., Whalley, B. J. and Williams, C. M. (2010) A low delta-9-tetrahydrocannabinol cannabis extract induces hyperphagia in rats. Behavioural Pharmacology, 21 (8). pp. 769-772. ISSN 0955-8810 doi: 10.1097/FBP.0b013e328340a062

Hill, A. J., Weston, S. E., Jones, N., Smith, I., Bevan , S., Williamson, E. M., Stephens, G. J., Williams, C. M. and Whalley, B. J. (2010) Δ9-tetrahydrocannabivarin suppresses in vitro epileptiform and in vivo seizure activity in adult rat. Epilepsia, 51 (8). pp. 1522-1532. ISSN 0013-9580 doi: 10.1111/j.1528-1167.2010.02523.x

Farrimond, J., Whalley, B. J. and Williams, C. M. (2010) Cannabis constituents modulate ∆9-tetrahydrocannabinol-induced hyperphagia in rats. Psychopharmacology, 210 (1). pp. 97-106. ISSN 0033-3158 doi: 10.1007/s00213-010-1821-z

Aitchison, E., Weston, S. E., Constanti, A. and Whalley, B. J. (2010) Anticholinesterase-induced epileptiform activity in immature rat piriform cortex slices, in vitro. Neuroscience Letters, 473 (3). pp. 252-256. ISSN 0304-3940 doi: 10.1016/j.neulet.2010.02.060

Jones, N. A., Hill, A. J., Smith, I., Bevan, S. A., Williams, C. M., Whalley, B. J. and Stephens, G. J. (2010) Cannabidiol displays antiepileptiform and antiseizure properties in vitro and in vivo. Journal of Pharmacology and Experimental Therapeutics, 332 (2). pp. 569-577. ISSN 0022-3565 doi: 10.1124/jpet.109.159145

Warwick, K., Xydas, D., Nasuto, S. J., Becerra, V. M., Hammond, M. W., Downes, J., Marshall, S. and Whalley, B. J. (2010) Controlling a mobile robot with a biological brain. Defence Science Journal, 60 (1). pp. 5-14. ISSN 0011-748X

Hill, A. J., Jones, N., Williams, C. M., Stephens, G. J. and Whalley, B. J. (2010) Development of multi-electrode array screening for anticonvulsants in acute rat brain slices. Journal of Neuroscience Methods, 185 (2). 246 -256 . ISSN 0165-0270 doi: 10.1016/j.jneumeth.2009.10.007

Whalley, B. J., Stephens, G. J. and Constanti, A. (2009) Investigation of the effects of the novel anticonvulsant compound carisbamate(RWJ-333369) on rat piriform cortical neurones in vitro. British Journal of Pharmacology, 156 (6). pp. 994-1008. ISSN 0007-1188 doi: 10.1111/j.1476-5381.2008.00110.x

Farrimond, J., Hill, A. J., Jones, N., Stephens, G. J., Whalley, B. J. and Williams, C. M. (2009) A cost-effective high-throughput digital system for observation and acquisition of animal behavioral data. Behavior Research Methods, 41 (2). pp. 446-451. ISSN 1554-351X doi: 10.3758/BRM.41.2.446

Dennis, I., Whalley, B. J. and Stephens, G. J. (2008) Effects of Delta9-tetrahydrocannabivarin on [35S]GTPgammaS binding in mouse brain cerebellum and piriform cortex membranes. British Journal of Pharmacology, 154 (6). pp. 1349-58. ISSN 0007-1188 doi: 10.1038/bjp.2008.190

Ma, Y. L., Weston, S. E., Whalley, B. J. and Stephens, G. J. (2008) The phytocannabinoid Delta(9)-tetrahydrocannabivarin modulates inhibitory neurotransmission in the cerebellum. British Journal of Pharmacology, 154 (1). pp. 204-215. ISSN 0007-1188 doi: 10.1038/bjp.2008.57

Ma, Y.-L., Weston, S.E. , Whalley, B.J. and Stephens, G.J. (2008) The phytocannabinoid Δ9-tetrahydrocannabivarin modulates inhibitory neurotransmission in the cerebellum. British Journal of Pharmacology, 154 (1). pp. 204-215. ISSN 0007-1188 doi: 10.1038/bjp.2008.57

Patel, N. A., Weston, S. E., Constanti, A., Halliwell, J. V. and Whalley, B. J. (2007) Cholinergic modulation of intrinsic fibre-evoked excitatory transmission contains a nicotinic component in immature but not adult rat piriform cortex, in vitro. Neuroscience Letters, 425 (1). pp. 43-48. ISSN 0304-3940 doi: 10.1016/j.neulet.2007.08.005

Whalley, B. J. and Constanti, A. (2006) Developmental changes in presynaptic muscarinic modulation of excitatory and inhibitory neurotransmission in rat piriform cortex in vitro: relevance to epileptiform bursting susceptibility. Neuroscience, 140 (3). pp. 939-956. ISSN 0306-4522 doi: 10.1016/j.neuroscience.2006.02.046

Whalley, B. J., Postlethwaite, M. and Constanti, A. (2005) Further characterization of muscarinic agonist-induced epileptiform bursting activity in immature rat piriform cortex, in vitro. Neuroscience, 134 (2). pp. 549-566. ISSN 0306-4522 doi: 10.1016/j.neuroscience.2005.04.018

Whalley, B. J., Wilkinson, J. D., Williamson, E. M. and Constanti, A. (2004) A novel component of cannabis extract potentiates excitatory synaptic transmission in rat olfactory cortex in vitro. Neuroscience Letters, 365 (1). pp. 58-63. ISSN 0304-3940 doi: 10.1016/j.neulet.2004.04.044

Wilkinson, J.D., Whalley, B. J., Baker, D., Pryce, G., Constanti, A., Gibbons, S. and Williamson, E. M. (2003) Medicinal cannabis: is delta9-tetrahydrocannabinol necessary for all its effects? Journal of Pharmacy and Pharmacology, 55 (12). pp. 1687-1694. ISSN 0022-3573 doi: DOI:10.1211/0022357022304

Book or Report Section

Warwick, K., Nasuto, S. J., Becerra, V. M. and Whalley, B. J. (2011) Experiments with an in-vitro robot brain. In: Yang, C. (ed.) Computing with instinct: rediscovering artificial intelligence. Lecture notes in computer science (5987). Springer, pp. 1-16, 1st Edition, XIII, 163 p. ISBN 9783642197567 (Sub series: lecture notes in artifical intelligence)

Weston, S.E., Whalley, B.J., Wilkinson, J.D. and Williamson, E.M. (2007) Medicinal cannabis: new findings on extracts and minor cannabinoids. In: Capasso, A. (ed.) Recent developments in medicinal plant research. Research Signpost, Trivandrum, Kerala, India, pp. 39-62. ISBN 9788130801605

Conference or Workshop Item

Miranda, E. R., Nasuto, S., Troisi, A. R., Downes, J., Chiaramonte, A., Spencer, M., Hammond, M., Xydas, D., Whalley, B., Becerra, V. and Warwick, K. (2011) A musical instrument using in vitro neural networks. In: International Computer Music Conference (ICMC 2011), 31 Jul - 5 Aug 2011, Huddersfield, pp. 567-570.

Valderrama-Gonzalez, G. D., Gasson, M. N., Warwick, K. and Whalley, B. J. (2010) Prosthesis grasp reflex via peripheral nerve control: an in vitro study. In: IEEE 2010 9th International Conference on Cybernetic Intelligent Systems (CIS), 1-2 September 2010, University of Reading, UK, pp. 20-25. (IEEE, London)

Xydas, D., Spencer, M., Downes, J., Hammond, M. W. J., Becerra, V. M., Warwick, K., Whalley, B. J. and Nasuto, S. J. (2010) Application of Poisson-based hidden Markov models to in-vitro neuronal data. In: 9th IEEE International Conference on Cybernetic Intelligent Systems, 1-2 Sept 2010, Reading, UK.

Spencer, M., Xydas, D., Downes, J. H., Hammond, M., Becerra, V., Warwick, K., Whalley, B. J. and Nasuto, S. J. (2010) Investigation of spatio-temporal dependencies in neuronal functional connectivity. In: 9th IEEE International Conference on Cybernetic Intelligent Systems, 1-2 Sept 2010, Reading, UK.

Weston, S. E., Williamson, E. M., Constanti, A., Stephens, G. J. and Whalley, B. J. (2006) Tetrahydrocannabivarin exhibits anticonvulsant effects in a piriform cortical brain slice model of epileptiform activity. In: British Pharmacological Society Winter Meeting 2006.

Book

Whalley, B.J., Fletcher, K.E., Weston, S.E., Howard, R.L. and Rawlinson, C.F. (2008) Foundation in pharmacy practice. Pharmaceutical, London. ISBN 9780853697473

This list was generated on Mon Sep 1 19:41:53 2014 BST.

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