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Pax gene expression in the developing central nervous system of Ciona intestinalis

Mazet, F., Hutt, J. A., Millard, J. and Shimeld, S. A. (2003) Pax gene expression in the developing central nervous system of Ciona intestinalis. Gene Expression Patterns, 3 (6). pp. 743-745. ISSN 1567-133X

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To link to this item DOI: 10.1016/s1567-133x(03)00137-6


We compare the expression patterns in Ciona intestinalis of three members of the Pax gene family, CiPax3/7, CiPax6 and Cipax2/5/8. All three genes are expressed in restricted patterns in the developing central nervous system. At the tailbud stage, CiPax3/7 is present in three patches in the brain and along the posterior neural tube, CiPax6 throughout the anterior brain and along the posterior neural tube and CiPax2/5/8 in a restricted region of the posterior brain. Double in situ hybridisations were used to identify areas of overlap between the expression of different genes. This showed that CiPax3/7 overlaps with the boundaries of CiPax6 expression in the anterior brain, and with CiPax2/5/8 in the posterior brain. The overlap between CiPax3/7 and CiPax2/5/8 is unlike that described in the ascidian Halocynthia rorezti. (C) 2003 Elsevier B.V. All rights reserved.

Item Type:Article
Divisions:Life Sciences > School of Biological Sciences
ID Code:10817
Uncontrolled Keywords:Ciona, pax, embryo, nervous system, in situ hybridisation

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