Accessibility navigation

Synthesis of linked heterocycles via use of bis-acetylenic compounds

Smith, C. ORCID:, Tchabanenko, K., Adlington, R.M. and Baldwin, J.E. (2006) Synthesis of linked heterocycles via use of bis-acetylenic compounds. Tetrahedron Letters, 47 (19). pp. 3209-3212. ISSN 0040-4039

Full text not archived in this repository.

It is advisable to refer to the publisher's version if you intend to cite from this work. See Guidance on citing.

To link to this item DOI: 10.1016/j.tetlet.2006.03.052


Linked bis-pyrazoles, a pyrazolyl-isoxazole, a pyrazolyl-pyrimidine and a pyrazolyl-triazole were synthesized starting with commercially available 1,4-bis(trimethylsilyl)-1,3-butadiyne 1 or readily available bis-acetylenic diketone 22. A stepwise approach based on the use of 1 allowed the synthesis of nonsymmetrically substituted bis-pyrazoles and linked heterocycles with two different cores whereas a symmetric approach based on the use of 22 allowed a very short synthesis of symmetric bis-pyrazoles.

Item Type:Article
Divisions:No Reading authors. Back catalogue items
ID Code:37117

University Staff: Request a correction | Centaur Editors: Update this record

Page navigation