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Comparative analysis of intestinal tract models

Williams, C. F., Walton, G. ORCID:, Jiang, L., Plummer, S., Garaiova, I. and Gibson, G. R. (2015) Comparative analysis of intestinal tract models. Annual Review of Food Science and Technology, 6 (1). pp. 329-350. ISSN 1941-1413

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To link to this item DOI: 10.1146/annurev-food-022814-015429


The human gut is a complex ecosystem occupied by a diverse microbial community. Modulation of this microbiota impacts health and disease. The definitive way to investigate the impact of dietary intervention on the gut microbiota is a human trial. However, human trials are expensive and can be difficult to control; thus, initial screening is desirable. Utilization of a range of in vitro and in vivo models means that useful information can be gathered prior to the necessity for human intervention. This review discusses the benefits and limitations of these approaches.

Item Type:Article
Divisions:Life Sciences > School of Chemistry, Food and Pharmacy > Department of Food and Nutritional Sciences > Food Microbial Sciences Research Group
ID Code:40427
Publisher:Annual Reviews

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