Number of items: 34.
Article
Mitchell, J. L., Dunster, J. L. ORCID: https://orcid.org/0000-0001-8986-4902, Kriek, N., Unsworth, A. J., Sage, T., Mohammed, Y. M. M., De Simone, I., Taylor, K. A. ORCID: https://orcid.org/0000-0002-4599-7727, Bye, A. P. ORCID: https://orcid.org/0000-0002-2061-2253, Ólafsson, G., Brunton, M., Mark, S., Dymott, L. D., Whyte, A., Ruparelia, N., Mckenna, C., Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 and Jones, C. I. ORCID: https://orcid.org/0000-0001-7537-1509
(2023)
The rate of platelet activation determines thrombus size and structure at arterial shear.
Journal of Thrombosis and Haemostasis, 21 (8).
pp. 2248-2259.
ISSN 1538-7836
doi: https://doi.org/10.1016/j.jtha.2023.03.044
Mitchell, J. L., Little, G., Bye, A. P. ORCID: https://orcid.org/0000-0002-2061-2253, Gaspar, R. S., Unsworth, A. J., Kriek, N., Sage, T., Stainer, A., Sangowawa, I., Morrow, G. B., Bastos, R. N., Shapiro, S., Desborough, M. J. R., Curry, N., Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352, Whyte, C. S., Mutch, N. J. and Jones, C. I. ORCID: https://orcid.org/0000-0001-7537-1509
(2023)
Platelet factor XIII-A regulates platelet function and promotes clot retraction and stability.
Research and Practice in Thrombosis and Haemostasis, 7 (5).
100200.
ISSN 2475-0379
doi: https://doi.org/10.1016/j.rpth.2023.100200
Bye, A. P. ORCID: https://orcid.org/0000-0002-2061-2253, Kriek, N., Sage, T., Rawlings, S. J., Prodger, C., Kesavan, M., Lees, C., Booth, S., Cowen, L. G., Shefferd, K., Desborough, M. J., Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 and Eyre, T. A.
(2023)
Pirtobrutinib results in reversible platelet dysfunction compared to ibrutinib and acalabrutinib.
Haematologica, 108 (5).
ISSN 1592-8721
doi: https://doi.org/10.3324/haematol.2022.281402
Mitchell, J. L., Khan, D., Rana, R. H., Kriek, N., Unsworth, A. J., Sage, T., Bye, A. P. ORCID: https://orcid.org/0000-0002-2061-2253, Laffan, M., Shapiro, S., Thakurta, A., Grech, H., Ramasamy, K. and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352
(2023)
Multiple myeloma and its treatment contribute to increased platelet reactivity.
Platelets, 34 (1).
2264940.
ISSN 1369-1635
doi: https://doi.org/10.1080/09537104.2023.2264940
Kriek, N., Nock, S. H., Sage, T., Khalifa, B., Bye, A. P. ORCID: https://orcid.org/0000-0002-2061-2253, Mitchell, J. L., Thomson, S., McLaughlin, M. G., Jones, S., Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 and Unsworth, A. J. ORCID: https://orcid.org/0000-0003-3809-5984
(2022)
Cucurbitacins elicit anti-platelet activity via perturbation of the cytoskeleton and integrin function.
Thrombosis and Haemostasis, 122 (07).
pp. 1115-1129.
ISSN 0340-6245
doi: https://doi.org/10.1055/a-1788-5322
Kempster, C., Butler, G., Kuznecova, E., Taylor, K. A. ORCID: https://orcid.org/0000-0002-4599-7727, Kriek, N., Little, G., Sowa, M. A., Sage, T., Johnson, L. J. ORCID: https://orcid.org/0000-0002-0006-1511, Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 and Pollitt, A. Y. ORCID: https://orcid.org/0000-0001-8706-5154
(2022)
Fully automated platelet differential interference contrast image analysis via deep learning.
Scientific Reports, 12.
4614.
ISSN 2045-2322
doi: https://doi.org/10.1038/s41598-022-08613-2
Dunster, J. ORCID: https://orcid.org/0000-0001-8986-4902, Bye, A. ORCID: https://orcid.org/0000-0002-2061-2253, Kriek, N., Sage, T., Mitchell, J., Kempster, C., Batista, J., KcKinney, H., Thomas, P., Jones, C. ORCID: https://orcid.org/0000-0001-7537-1509, Downes, K., Unsworth, A. and Gibbins, J. ORCID: https://orcid.org/0000-0002-0372-5352
(2021)
Multi-parameter phenotyping of platelet reactivity for stratification of human cohorts.
Blood Advances, 5 (20).
pp. 4017-4030.
ISSN 2473-9529
doi: https://doi.org/10.1182/bloodadvances.2020003261
Bye, A. P. ORCID: https://orcid.org/0000-0002-2061-2253, Hoepel, W., Mitchell, J. L., Jegouic, S. M., Loureiro, S. ORCID: https://orcid.org/0009-0000-8886-6893, Sage, T., Vidarsson, G., Nouta, J., Wuhrer, M., de Taeye, S. W., van Gils, M., Kriek, N., Cooper, N., Jones, I. ORCID: https://orcid.org/0000-0002-7738-2516, den Dunnen, J. and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352
(2021)
Aberrant glycosylation of anti-SARS-CoV-2 spike IgG is a pro-thrombotic stimulus for platelets.
Blood, 138 (16).
pp. 1481-1489.
ISSN 0006-4971
doi: https://doi.org/10.1182/blood.2021011871
Unsworth, A. J., Bye, A. P. ORCID: https://orcid.org/0000-0002-2061-2253, Sage, T., Gaspar, R. S., Eaton, N., Drew, C., Stainer, A., Kriek, N., Volberding, P. J., Hutchinson, J. L., Riley, R., Jones, S., Mundell, S. J., Cui, W., Falet, H. and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352
(2021)
Anti-platelet properties of Pim kinase inhibition is mediated through disruption of thromboxane A2 receptor signalling.
Haematologica, 106 (7).
ISSN 1592-8721
doi: https://doi.org/10.3324/haematol.2019.223529
Simoes Gaspar, R., Sage, T., Little, G., Kriek, N., Pula, G. and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352
(2021)
Protein disulphide isomerase and NADPH oxidase 1 cooperate
to control platelet function and are associated with cardiometabolic disease risk factors.
Antioxidants, 10 (3).
497.
ISSN 2076-3921
doi: https://doi.org/10.3390/antiox10030497
Sahli, K. A., Flora, G. D., Sasikumar, P., Maghrabi, A. H., Holbrook, L., AlOuda, S. K., Elgheznawy, A., Sage, T., Stainer, A. R., Adiyaman, R., AboHassan, M., Crescente, M., Kriek, N., Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517, Bye, A. P. ORCID: https://orcid.org/0000-0002-2061-2253, Unsworth, A. J., Jones, C. I. ORCID: https://orcid.org/0000-0001-7537-1509, McGuffin, L. J. ORCID: https://orcid.org/0000-0003-4501-4767 and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352
(2021)
Structural, functional and mechanistic insights uncover the fundamental role of orphan connexin-62 in platelets.
Blood, 137 (6).
pp. 830-843.
ISSN 0006-4971
doi: https://doi.org/10.1182/blood.2019004575
Gaspar, R. S., Unsworth, A. J., Al-Dibouni, A., Bye, A. P., Sage, T., Stewart, M., Cox, R. D., Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352, Sellayah, D. and Hughes, C. ORCID: https://orcid.org/0000-0002-9790-5820
(2021)
Maternal and offspring high-fat diet leads to platelet hyperactivation in male mice offspring.
Scientific Reports, 11.
1473.
ISSN 2045-2322
doi: https://doi.org/10.1038/s41598-020-80373-3
Dunster, J. L. ORCID: https://orcid.org/0000-0001-8986-4902, Unsworth, A. J., Bye, A. P. ORCID: https://orcid.org/0000-0002-2061-2253, Haining, E. J.,, Sowa, M. A., Di, Y., Sage, T., Pallini, C., Pike, J. A., Hardy, A. T., Nieswandt, B., García, Á., Watson, S. P., Poulter, N. S., Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 and Pollitt, A. Y. ORCID: https://orcid.org/0000-0001-8706-5154
(2020)
Interspecies differences in protein expression do not impact the spatiotemporal regulation of glycoprotein VI mediated activation.
Journal of Thrombosis and Haemostasis, 18 (2).
pp. 485-496.
ISSN 1538-7836
doi: https://doi.org/10.1111/jth.14673
Flora, G. D., Sahli, K. A., Sasikumar, P., Holbrook, L.-M., Stainer, A. R., Alouda, S. K., Crescente, M., Sage, T., Unsworth, A. J. and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352
(2019)
Non-genomic effects of the Pregnane X Receptor negatively regulate platelet functions, thrombosis and haemostasis.
Scientific Reports, 9 (1).
17210.
ISSN 2045-2322
doi: https://doi.org/10.1038/s41598-019-53218-x
Unsworth, A. J., Bye, A. P. ORCID: https://orcid.org/0000-0002-2061-2253, Kriek, N., Sage, T., Osborne, A. A., Donaghy, D. and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352
(2019)
Cobimetinib and trametinib inhibit platelet MEK but do not cause platelet dysfunction.
Platelets, 30 (6).
pp. 762-772.
ISSN 0953-7104
doi: https://doi.org/10.1080/09537104.2018.1514107
Sasikumar, P., AlOuda, K. S., Kaiser, W. J., Holbrook, L. M., Kriek, N., Unsworth, A. J., Bye, A. P. ORCID: https://orcid.org/0000-0002-2061-2253, Sage, T., Ushioda, R. W., Nagata, K., Farndale, R. W. and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352
(2018)
The chaperone protein HSP47: a platelet collagen binding protein that contributes to thrombosis and haemostasis.
Journal of Thrombosis and Haemostasis, 16 (5).
pp. 946-959.
ISSN 1538-7933
doi: https://doi.org/10.1111/jth.13998
Bye, A. P. ORCID: https://orcid.org/0000-0002-2061-2253, Unsworth, A. J., Desborough, M. J., Hildyard, C. A. T., Appleby, N., Bruce, D., Kriek, N., Nock, S. H., Sage, T., Hughes, C. E. ORCID: https://orcid.org/0000-0002-9790-5820 and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352
(2017)
Severe platelet dysfunction in NHL patients receiving ibrutinib is absent in patients receiving acalabrutinib.
Blood Advances, 1 (26).
pp. 2610-2623.
ISSN 2473-9529
doi: https://doi.org/10.1182/bloodadvances.2017011999
Unsworth, A. J., Bye, A. P. ORCID: https://orcid.org/0000-0002-2061-2253, Tannetta, D. S., Desborough, M. J. R., Kriek, N., Sage, T., Allan, H. E., Crescente, M., Yaqoob, P. ORCID: https://orcid.org/0000-0002-6716-7599, Warner, T. D., Jones, C. I. ORCID: https://orcid.org/0000-0001-7537-1509 and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352
(2017)
Farnesoid X receptor and liver X receptor ligands initiate formation of coated platelets.
Arteriosclerosis, thrombosis, and vascular biology, 37 (8).
pp. 1482-1493.
ISSN 1524-4636
doi: https://doi.org/10.1161/ATVBAHA.117.309135
Unsworth, A. J., Flora, G. D., Sasikumar, P., Bye, A. P. ORCID: https://orcid.org/0000-0002-2061-2253, Sage, T., Kriek, N., Crescente, M. and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352
(2017)
RXR ligands negatively regulate thrombosis and hemostasis.
Arteriosclerosis Thrombosis and Vascular Biology, 37 (5).
pp. 812-822.
ISSN 1524-4636
doi: https://doi.org/10.1161/ATVBAHA.117.309207
Unsworth, A. J., Kriek, N., Bye, A. P. ORCID: https://orcid.org/0000-0002-2061-2253, Naran, K., Sage, T., Flora, G. D. and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352
(2017)
PPARγ agonists negatively regulate αIIbβ3 integrin outside-in signalling and platelet function through upregulation of protein kinase A activity.
Journal of Thrombosis and Haemostasis, 15 (2).
pp. 356-369.
ISSN 1538-7933
doi: https://doi.org/10.1111/jth.13578
Moraes, L. A., Unsworth, A. J., Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517, Ali, M. S., Sasikumar, P., Sage, T., Flora, G. D., Bye, A. P. ORCID: https://orcid.org/0000-0002-2061-2253, Kriek, N., Dorchies, E., Molendi-Coste, O., Dombrowicz, D., Staels, B., Bishop-Bailey, D. and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352
(2016)
Farnesoid X Receptor and its ligands inhibit the function of platelets.
Arteriosclerosis Thrombosis and Vascular Biology, 36 (12).
pp. 2324-2333.
ISSN 1524-4636
doi: https://doi.org/10.1161/ATVBAHA.116.308093
Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517, Sage, T., Rana, R. H., Schenk, M. P., Ali, M. S., Unsworth, A. J., Jones, C. I. ORCID: https://orcid.org/0000-0001-7537-1509, Stainer, A. R., Kriek, N. K., Moraes, L. A. and Gibbins, J. ORCID: https://orcid.org/0000-0002-0372-5352
(2015)
EphB2 regulates contact-dependent and independent signalling to control platelet function.
Blood, 125 (4).
pp. 720-730.
ISSN 0006-4971
doi: https://doi.org/10.1182/blood-2014-06-585083
Jones, C. I. ORCID: https://orcid.org/0000-0001-7537-1509, Sage, T., Moraes, L. A., Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517, Hussain, U., Tucker, K. L., Barrett, N. E. ORCID: https://orcid.org/0000-0001-9123-1100 and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352
(2014)
Platelet endothelial cell adhesion molecule-1 inhibits platelet response to thrombin and von Willebrand factor by regulating the internalization of glycoprotein Ib via AKT/glycogen synthase kinase-3/dynamin and integrin αIIbβ3.
Arteriosclerosis Thrombosis and Vascular Biology, 34 (9).
pp. 1968-1976.
ISSN 1079-5642
doi: https://doi.org/10.1161/ATVBAHA.114.304097
Jones, C. I. ORCID: https://orcid.org/0000-0001-7537-1509, Tucker, K. L., Sasikumar, P., Sage, T., Kaiser, W. J., Moore, C., Emerson, M. and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352
(2014)
Integrin-linked kinase regulates the rate of platelet activation and is essential for the formation of stable thrombi.
Journal of Thrombosis and Haemostasis, 12 (8).
pp. 1342-1352.
ISSN 1538-7933
doi: https://doi.org/10.1111/jth.12620
Waller, A. K., Sage, T., Kumar, C., Carr, T., Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 and Clarke, S. R.
(2013)
Staphylococcus aureus lipoteichoic acid inhibits platelet activation and thrombus formation via the Paf receptor.
Journal of Infectious Diseases, 208 (12).
pp. 2046-2057.
ISSN 1537-6613
doi: https://doi.org/10.1093/infdis/jit398
Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517, Ali, M. S., Moraes, L. A., Sage, T., Lewis, K. R., Jones, C. I. ORCID: https://orcid.org/0000-0001-7537-1509 and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352
(2013)
Tangeretin regulates platelet function through inhibition of phosphoinositide 3-Kinase and cyclic nucleotide signaling.
Arteriosclerosis Thrombosis and Vascular Biology, 33 (12).
pp. 2740-2749.
ISSN 1079-5642
doi: https://doi.org/10.1161/ATVBAHA.113.301988
Moraes, L. A., Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517, Sasikumar, P., Ali, M. S., Kriek, N. K., Sage, T. and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352
(2013)
Antithrombotic actions of statins involve PECAM-1 signalling.
Blood, 122 (18).
pp. 3188-3196.
ISSN 0006-4971
doi: https://doi.org/10.1182/blood-2013-04-491845
Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517, Moraes, L. A., Sage, T., Ali, M. S., Lewis, K. R., Mayhaut-Smith, M. P., Oviedo-Orta, E., Simon, A. M. and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352
(2013)
Connexin40 regulates platelet function.
Nature Communications, 4.
pp. 2564-2572.
ISSN 2041-1723
doi: https://doi.org/10.1038/ncomms3564
Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517, Jones, C. I. ORCID: https://orcid.org/0000-0001-7537-1509, Sasikumar, P., Moraes, L. A., Munger, S. J., Wright, J. R., Ali, M. S., Sage, T., Kaiser, W. J., Tucker, K. L., Stain, C. J., Bye, A. P., Jones, S., Oviedo-Orta, E., Simon, A. M., Mahaut-Smith, M. P. and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352
(2012)
Gap junctions and connexin hemichannels underpin hemostasis and thrombosis.
Circulation, 125 (20).
pp. 2479-2491.
ISSN 0009-7322
doi: https://doi.org/10.1161/CIRCULATIONAHA.112.101246
Spyridon, M., Moraes, L. A., Jones, C. I. ORCID: https://orcid.org/0000-0001-7537-1509, Sage, T., Sasikumar, P., Bucci, G. and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352
(2011)
LXR as a novel antithrombotic target.
Blood, 117 (21).
pp. 5751-5761.
ISSN 1528-0020
doi: https://doi.org/10.1182/blood-2010-09-306142
Moraes, L. A., Barrett, N. E. ORCID: https://orcid.org/0000-0001-9123-1100, Jones, C. ORCID: https://orcid.org/0000-0001-7537-1509, Holbrook, L. M., Spyridon, M., Sage, T., Newman, D. K. and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352
(2010)
Platelet endothelial cell adhesion molecule-1 regulates collagen-stimulated platelet function by modulating the association of phosphatidylinositol 3-kinase with Grb-2-associated binding protein-1 and linker for activation of T cells.
Journal of Thrombosis and Haemostasis, 8 (11).
pp. 2530-2541.
ISSN 1538-7933
doi: https://doi.org/10.1111/j.1538-7836.2010.04025.x
Moraes, L. A., Spyridon, M., Kaiser, W. J., Jones, C. ORCID: https://orcid.org/0000-0001-7537-1509, Sage, T., Atherton, R. E. and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352
(2010)
Non-genomic effects of PPARgamma ligands: inhibition of GPVI-stimulated platelet activation.
Journal of Thrombosis and Haemostasis, 8 (3).
pp. 577-587.
ISSN 1538-7933
doi: https://doi.org/10.1111/j.1538-7836.2009.03732.x
Cicmil, M., Thomas, J. M., Sage, T., Barry, F. A., Leduc, M., Bon, C. and Gibbins, J. ORCID: https://orcid.org/0000-0002-0372-5352
(2000)
Collagen, convulxin, and thrombin stimulate aggregation-independent tyrosine phosphorylation of CD31 in platelets. Evidence for the involvement of Src family kinases.
The Journal of biological chemistry, 275 (35).
pp. 27339-27347.
ISSN 0021-9258
doi: https://doi.org/10.1074/jbc.M003196200
Book or Report Section
Tucker, K. L., Sage, T. and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352
(2011)
Clot retraction.
In: Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 and Mahaut-Smith, M. P. (eds.)
Platelets and Megakaryocytes. vol. 3, Additional Protocols and Perspectives.
Methods in Molecular Biology, vol. 788.
Humana Press, pp. 101-108.
ISBN 9781617793066
This list was generated on Fri Dec 13 04:58:51 2024 UTC.