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Waller, A. K., Birch, K., Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 and Clarke, S. R. (2022) Activation of Human Platelets by Staphylococcus aureus Secreted Protease Staphopain A. Pathogens, 11 (11). 1237. ISSN 2076-0817 doi: https://doi.org/10.3390/pathogens11111237

De Simone, I., Baaten, C. C. F. M. J., Jandrot-Perrus, M., Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352, ten Cate, H., Heemskerk, J. W. M., Jones, C. I. ORCID: https://orcid.org/0000-0001-7537-1509 and van der Meijden, P. E. J. (2022) Coagulation factor XIIIa and activated protein C activate platelets via GPVI and PAR1. International Journal of Molecular Sciences, 23 (18). 10203. ISSN 1422-0067 doi: https://doi.org/10.3390/ijms231810203

Wright, J. R., Jones, S., Parvathy, S., Kaczmarek, L. K., Forsythe, I., Farndale, R. W., Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 and Mahaut-Smith, M. P. (2022) The voltage-gated K+ channel Kv1.3 modulates platelet motility and α2β1 integrin-dependent adhesion to collagen. Platelets, 33 (3). pp. 451-461. ISSN 0953-7104 doi: https://doi.org/10.1080/09537104.2021.1942818

Dunster, J., Bye, A., Kriek, N., Sage, T., Mitchell, J., Kempster, C., Batista, J., KcKinney, H., Thomas, P., Jones, C. ORCID: https://orcid.org/0000-0001-7537-1509, Downes, K., Unsworth, A. and Gibbins, J. ORCID: https://orcid.org/0000-0002-0372-5352 (2021) Multi-parameter phenotyping of platelet reactivity for stratification of human cohorts. Blood Advances, 5 (20). pp. 4017-4030. ISSN 2473-9529 doi: https://doi.org/10.1182/bloodadvances.2020003261

Simoes Gaspar, R. and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 (2021) Thiol isomerases orchestrate thrombosis and haemostasis. Antioxidants & Redox Signaling, 35 (13). ISSN 1523-0864 doi: https://doi.org/10.1089/ars.2021.0086

Bye, A. P., Hoepel, W., Mitchell, J. L., Jegouic, S. M., Loureiro, S., Sage, T., Vidarsson, G., Nouta, J., Wuhrer, M., de Taeye, S. W., van Gils, M., Kriek, N., Cooper, N., Jones, I. ORCID: https://orcid.org/0000-0002-7738-2516, den Dunnen, J. and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 (2021) Aberrant glycosylation of anti-SARS-CoV-2 spike IgG is a pro-thrombotic stimulus for platelets. Blood, 138 (16). pp. 1481-1489. ISSN 0006-4971 doi: https://doi.org/10.1182/blood.2021011871

Gaspar, R. S., Mansilla, S., Vieira, V. A., da Silva, L. B., Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352, Castro, L., Trostchansky, A. and de A. Paes, A. M. (2021) The protein disulphide isomerase inhibitor CxxCpep modulates oxidative burst and mitochondrial function in platelets. Free Radical Biology and Medicine, 172. pp. 668-674. ISSN 0891-5849 doi: https://doi.org/10.1016/j.freeradbiomed.2021.07.011

Unsworth, A. J., Bye, A. P., Sage, T., Gaspar, R. S., Eaton, N., Drew, C., Stainer, A., Kriek, N., Volberding, P. J., Hutchinson, J. L., Riley, R., Jones, S., Mundell, S. J., Cui, W., Falet, H. and Gibbins, J. M. (2021) Anti-platelet properties of Pim kinase inhibition is mediated through disruption of thromboxane A2 receptor signalling. Haematologica, 106 (7). ISSN 1592-8721 doi: https://doi.org/10.3324/haematol.2019.223529

Taylor, K. A., Little, G. and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 (2021) Mind the gap: connexins and pannexins in platelet function. Platelets, 32 (7). pp. 888-894. ISSN 0953-7104 doi: https://doi.org/10.1080/09537104.2021.1902971

Simoes Gaspar, R., Sage, T., Little, G., Kriek, N., Pula, G. and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 (2021) Protein disulphide isomerase and NADPH oxidase 1 cooperate to control platelet function and are associated with cardiometabolic disease risk factors. Antioxidants, 10 (3). 497. ISSN 2076-3921 doi: https://doi.org/10.3390/antiox10030497

Gaspar, R. S., Ferreira, P., Mitchell, J. L., Pula, G. and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 (2021) Platelet-derived extracellular vesicles express NADPH oxidase-1 (Nox-1), generate superoxide and modulate platelet function. Free Radical Biology and Medicine, 165. pp. 395-400. ISSN 0891-5849 doi: https://doi.org/10.1016/j.freeradbiomed.2021.01.051

Sahli, K. A., Flora, G. D., Sasikumar, P., Maghrabi, A. H., Holbrook, L., AlOuda, S. K., Elgheznawy, A., Sage, T., Stainer, A. R., Adiyaman, R., AboHassan, M., Crescente, M., Kriek, N., Vaiyapuri, S., Bye, A. P., Unsworth, A. J., Jones, C. I., McGuffin, L. J. and Gibbins, J. M. (2021) Structural, functional and mechanistic insights uncover the fundamental role of orphan connexin-62 in platelets. Blood, 137 (6). pp. 830-843. ISSN 0006-4971 doi: https://doi.org/10.1182/blood.2019004575

Holbrook, L.-M., Keeton, S. J., Sasikumar, P., Nock, S., Gelzinis, J., Brunt, E., Ryan, S., Pantos, M. M., Verbetsky, C. A., Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 and Kennedy, D. R. (2021) Zafirlukast is a broad-spectrum thiol isomerase inhibitor that inhibits thrombosis without altering bleeding times. British Journal of Pharmacology, 178 (3). pp. 550-563. ISSN 1476-5381 doi: https://doi.org/10.1111/bph.15291

Cai, H., Sasikumar, P., Little, G., Bihan, D., Hamaia, S. W., Zhou, A., Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 and Farndale, R. W. (2021) Identification of HSP47 binding site on native collagen and its implications on the development of HSP47 inhibitors. Biomolecules, 11 (7). 983. ISSN 2218-273X doi: https://doi.org/10.3390/biom11070983

Majeed, K. R., Al-Fahad, D., Jalood, H. H., Hantosh, H. A., Ali, M. K., Sakthivel, S., Williams, H. F., Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352, Patel, K., Baksh, M. F. and Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517 (2021) RhD blood type significantly influences susceptibility to contract COVID-19 among a study population in Iraq. F1000Research. ISSN 2046-1402 doi: https://doi.org/10.12688/f1000research.27777.1

Dunster, J., Mitchell, J., Mohammed, Y., Taylor, K., Gibbins, J. ORCID: https://orcid.org/0000-0002-0372-5352 and Jones, C. (2021) Kinetx: a combined flow cytometry assay and analysis software framework to quantitatively measure and categorize platelet activation in real-time. Journal of Visualized Experiments, 176. e62947. ISSN 1940-087X doi: https://doi.org/10.3791/62947

Gaspar, R. S., Unsworth, A. J., Al-Dibouni, A., Bye, A. P., Sage, T., Stewart, M., Cox, R. D., Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352, Sellayah, D. and Hughes, C. ORCID: https://orcid.org/0000-0002-9790-5820 (2021) Maternal and offspring high-fat diet leads to platelet hyperactivation in male mice offspring. Scientific Reports, 11. 1473. ISSN 2045-2322 doi: https://doi.org/10.1038/s41598-020-80373-3

Soriano Jerez, E. M., Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 and Hughes, C. E. ORCID: https://orcid.org/0000-0002-9790-5820 (2021) Targeting platelet inhibition receptors for novel therapies: PECAM-1 and G6b-B. Platelets, 32 (6). pp. 761-769. ISSN 0953-7104 doi: https://doi.org/10.1080/09537104.2021.1882668

Ferreira, P., Bozbas, E., Tannetta, D., Alroqaiba, N., Zhou, R., Crawley, J., Gibbins, J., Jones, C. ORCID: https://orcid.org/0000-0001-7537-1509, Ahnstrom, J. and Yaqoob, P. (2020) Mode of induction of platelet-derived extracellular vesicles is a critical determinant of their phenotype and function. Scientific Reports, 10 (1). 18061. ISSN 2045-2322 doi: https://doi.org/10.1038/s41598-020-73005-3

Al-Dibouni, A., Gaspar, R., Ige, S., Boateng, S., Cagampang, F. R., Gibbins, J., Cox, R. D. and Sellayah, D. (2020) Unique genetic and histological signatures of mouse pericardial adipose tissue. Nutrients, 12 (6). 1855. ISSN 2072-6643 doi: https://doi.org/10.3390/nu12061855

Martyanov, A. A., Balabin, F. A., Dunster, J. L., Panteleev, M. A., Gibbins, J. M. and Sveshnikov, A. N. (2020) Control of platelet CLEC-2-mediated activation by receptor clustering and tyrosine kinase signalling. Biophysical Journal, 118 (11). ISSN 0006-3495 doi: https://doi.org/10.1016/j.bpj.2020.04.023

lopes Pires, M. E., Ahmed, N. S., Vara, D., Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352, Pula, G. and Pugh, N. (2020) Zinc regulates reactive oxygen species generation in platelets. Platelets, 32 (3). pp. 368-377. ISSN 0953-7104 doi: https://doi.org/10.1080/09537104.2020.1742311

Dunster, J. L., Unsworth, A. J., Bye, A. P., Haining, E. J.,, Sowa, M. A., Di, Y., Sage, T., Pallini, C., Pike, J. A., Hardy, A. T., Nieswandt, B., García, Á., Watson, S. P., Poulter, N. S., Gibbins, J. M. and Pollitt, A. Y. (2020) Interspecies differences in protein expression do not impact the spatiotemporal regulation of glycoprotein VI mediated activation. Journal of Thrombosis and Haemostasis, 18 (2). pp. 485-496. ISSN 1538-7836 doi: https://doi.org/10.1111/jth.14673

Bye, A. P., Gibbins, J. M. and Mahaut-Smith, M. P. (2020) Ca2+ waves coordinate purinergic receptor–evoked integrin activation and polarization. Science Signaling, 13 (615). eaav7354. ISSN 1937-9145 doi: https://doi.org/10.1126/scisignal.aav7354

Gaspar, R. S., da Silva, S. A., Stapleton, J., Fontelles, J. L. d., Sousa, H. R., Chagas, V. T., Alsufyani, S., Trostchansky, A., Gibbins, J. M. and Paes, A. M. (2020) Myricetin, the main flavonoid in Syzygium cumini leaf, is a novel inhibitor of platelet thiol isomerases PDI and ERp5. Frontiers in Pharmacology, 10. 1678. ISSN 1663-9812 doi: https://doi.org/10.3389/fphar.2019.01678

Darling, T. K., Schenk, M. P., Zhou, C., Maloba, F. M., Mimche, P. N., Gibbins, J. M., Jobe, S. M. and Lamb, T. J. (2020) Platelet alpha-granules contribute to organ-specific pathologies in a mouse model of severe malaria. Blood Advances, 4 (1). pp. 1-8. ISSN 2473-9529 doi: https://doi.org/10.1182/bloodadvances.2019000773

Mazet, F., Tindall, M. J., Gibbins, J. M. and Fry, M. J. (2020) A model of the PI cycle reveals the regulating roles of lipid-binding proteins and pitfalls of using mosaic biological data. Scientific Reports, 10 (1). 13244. ISSN 2045-2322 doi: https://doi.org/10.1038/s41598-020-70215-7

Flora, G. D., Sahli, K. A., Sasikumar, P., Holbrook, L.-M., Stainer, A. R., Alouda, S. K., Crescente, M., Sage, T., Unsworth, A. J. and Gibbins, J. M. (2019) Non-genomic effects of the Pregnane X Receptor negatively regulate platelet functions, thrombosis and haemostasis. Scientific Reports, 9 (1). 17210. ISSN 2045-2322 doi: https://doi.org/10.1038/s41598-019-53218-x

Macwan, A. S., Boknas, N., Ntzouni, M. P., Ramstrom, S., Gibbins, J. M., Faxalv, L. and Lindahl, T. L. (2019) Gradient-dependent inhibition of stimulatory signaling from platelet G protein-coupled receptors. Haematologica, 104 (7). pp. 1482-1492. ISSN 1592-8721 doi: https://doi.org/10.3324/haematol.2018.205815

Stainer, A., Sasikumar, P., Bye, A., Unsworth, A., Holbrook, L., Tindall, M., Lovegrove, J. and Gibbins, J. (2019) Quercetin and its methylated metabolites possess anti-thrombotic properties that interact with aspirin to enhance its anti-platelet effects. TH Open, 3 (3). e244-e258. ISSN 2512-9465 doi: https://doi.org/10.1055/s-0039-1694028

Unsworth, A. J., Bye, A. P., Kriek, N., Sage, T., Osborne, A. A., Donaghy, D. and Gibbins, J. M. (2019) Cobimetinib and trametinib inhibit platelet MEK but do not cause platelet dysfunction. Platelets, 30 (6). pp. 762-772. ISSN 0953-7104 doi: https://doi.org/10.1080/09537104.2018.1514107

Salamah, M. F., Ravishankar, D., Vaiyapuri, R., Moraes, L. A., Patel, K., Perretti, M., Gibbins, J. M. and Vaiyapuri, S. (2019) The formyl peptide fMLF primes platelet activation and augments thrombus formation. Journal of Thrombosis and Haemostasis, 17 (7). pp. 1120-1133. ISSN 1538-7836 doi: https://doi.org/10.1111/jth.14466

Stainer, A. R., Sasikumar, P., Bye, A. P., Unsworth, A. P., Holbrook, L. M., Tindall, M., Lovegrove, J. A. and Gibbins, J. M. (2019) The metabolites of the dietary flavonoid quercetin possess potent antithrombotic activity, and interact with aspirin to enhance antiplatelet effects. TH Open, 3 (3). e244-e258. ISSN 2512-9465 doi: https://doi.org/10.1055/s-0039-1694028

Stefanini, L., Lee, R. H., Paul, D. S., O'Shaughnessy, E. C., Ghalloussi, D., Jones, C. I., Boulaftali, Y., Poe, K. O., Piatt, R., Kechele, D. O., Caron, K. M., Hahn, K. M., Gibbins, J. M. and Bergmeier, W. (2018) Functional redundancy between RAP1 isoforms in murine platelet production and function. Blood, 132 (18). pp. 1951-1962. ISSN 0006-4971 doi: https://doi.org/10.1182/blood-2018-03-838714

Belyaev, A. V., Dunster, J. L., Gibbins, J. M., Panteleev, M. A. and Volpert, V. (2018) Modelling thrombosis in silico: frontiers, challenges, unresolved problems and milestones. Physics of Life Reviews, 26-27. pp. 57-95. ISSN 1571-0645 doi: https://doi.org/10.1016/j.plrev.2018.02.005

Fuentos, E., Gibbins, J. M., Holbrook, L. M. and Palomo, I. (2018) NADPH oxidase 2 (NOX2): a key target of oxidative stress-mediated platelet activation and thrombosis. Trends in Cardiovascular Medicine, 28 (7). pp. 429-434. ISSN 1050-1738 doi: https://doi.org/10.1016/j.tcm.2018.03.001

Huang, Z., Barker, D., Gibbins, J. M. and Dash, P. R. (2018) Talin is a substrate for SUMOylation in migrating cancer cells. Experimental Cell Research, 370 (2). pp. 417-425. ISSN 0014-4827 doi: https://doi.org/10.1016/j.yexcr.2018.07.005

Bye, A. P. and Gibbins, J. M. (2018) Move along, nothing to see here: Btk inhibitors stop platelets sticking to plaques. Journal of Thrombosis and Haemostasis, 16 (8). pp. 1461-1463. ISSN 1538-7933 doi: https://doi.org/10.1111/jth.14201

Molica, F., Figueroa, X. F., Kwak, B. R., Isakson, B. E. and Gibbins, J. M. (2018) Connexins and pannexins in vascular function and disease. International Journal of Molecular Sciences, 19 (6). 1663. ISSN 1422-0067 doi: https://doi.org/10.3390/ijms19061663

Sasikumar, P., AlOuda, K. S., Kaiser, W. J., Holbrook, L. M., Kriek, N., Unsworth, A. J., Bye, A. P., Sage, T., Ushioda, R. W., Nagata, K., Farndale, R. W. and Gibbins, J. M. (2018) The chaperone protein HSP47: a platelet collagen binding protein that contributes to thrombosis and haemostasis. Journal of Thrombosis and Haemostasis, 16 (5). pp. 946-959. ISSN 1538-7933 doi: https://doi.org/10.1111/jth.13998

Unsworth, A. J., Flora, G. D. and Gibbins, J. M. (2018) Non-genomic effects of nuclear receptors: insights from the anucleate platelet. Cardiovascular Research, 114 (5). pp. 645-655. ISSN 0008-6363 doi: https://doi.org/10.1093/cvr/cvy044

Holbrook, L., Sandhar, G. K., Sasikumar, P., Schenk, M. P., Stainer, A. R., Sahli, K., Flora, G. D., Bicknell, A. B. and Gibbins, J. M. (2018) A humanized monoclonal antibody that inhibits platelet-surface ERp72 reveals a role for ERp72 in thrombosis. Journal of Thrombosis and Haemostasis, 16 (2). pp. 367-377. ISSN 1538-7836 doi: https://doi.org/10.1111/jth.13878

Salamah, M. F., Ravishankar, D., Kodji, X., Moraes, L. A., Williams, H. F., Vallance, T. M., Albadawi, D. A., Vaiyapuri, R., Watson, K., Gibbins, J. M., Brain, S. D., Perretti, M. and Vaiyapuri, S. (2018) The endogenous antimicrobial cathelicidin LL37 induces platelet activation and augments thrombus formation. Blood Advances, 2 (21). pp. 2973-2985. ISSN 2473-9529 doi: https://doi.org/10.1182/bloodadvances.2018021758

Bye, A. P., Unsworth, A. J., Desborough, M. J., Hildyard, C. A. T., Appleby, N., Bruce, D., Kriek, N., Nock, S. H., Sage, T., Hughes, C. E. and Gibbins, J. M. (2017) Severe platelet dysfunction in NHL patients receiving ibrutinib is absent in patients receiving acalabrutinib. Blood Advances, 1 (26). pp. 2610-2623. ISSN 2473-9529 doi: https://doi.org/10.1182/bloodadvances.2017011999

Unsworth, A. J., Bye, A. P., Tannetta, D. S., Desborough, M. J. R., Kriek, N., Sage, T., Allan, H. E., Crescente, M., Yaqoob, P., Warner, T. D., Jones, C. I. and Gibbins, J. M. (2017) Farnesoid X receptor and liver X receptor ligands initiate formation of coated platelets. Arteriosclerosis, thrombosis, and vascular biology, 37 (8). pp. 1482-1493. ISSN 1524-4636 doi: https://doi.org/10.1161/ATVBAHA.117.309135

Ilkan, Z., Wright, J. R., Goodall, A. H., Gibbins, J. M., Jones, C. I. and Mahaut-Smith, M. P. (2017) Evidence for shear-mediated Ca2+ entry through mechanosensitive cation channels in human platelets and a megakaryocytic cell line. The Journal of Biological Chemistry, 292 (22). pp. 9204-9217. ISSN 1083-351X doi: https://doi.org/10.1074/jbc.M116.766196

Williams, H. F., Vaiyapuri, R., Gajjeraman, P., Hutchinson, G., Gibbins, J. M., Bicknell, A. B. and Vaiyapuri, S. (2017) Challenges in diagnosing and treating snakebites in a rural population of Tamil Nadu, India: the views of clinicians. Toxicon, 130. pp. 44-46. ISSN 0041-0101 doi: https://doi.org/10.1016/j.toxicon.2017.02.025

Unsworth, A. J., Flora, G. D., Sasikumar, P., Bye, A. P., Sage, T., Kriek, N., Crescente, M. and Gibbins, J. M. (2017) RXR ligands negatively regulate thrombosis and hemostasis. Arteriosclerosis Thrombosis and Vascular Biology, 37 (5). pp. 812-822. ISSN 1524-4636 doi: https://doi.org/10.1161/ATVBAHA.117.309207

Unsworth, A. J., Kriek, N., Bye, A. P., Naran, K., Sage, T., Flora, G. D. and Gibbins, J. M. (2017) PPARγ agonists negatively regulate αIIbβ3 integrin outside-in signalling and platelet function through upregulation of protein kinase A activity. Journal of Thrombosis and Haemostasis, 15 (2). pp. 356-369. ISSN 1538-7933 doi: https://doi.org/10.1111/jth.13578

Lopes Pires, M. E., Clarke, S. R., Marcondes, S. and Gibbins, J. M. (2017) Lipopolysaccharide potentiates platelet responses via toll-like receptor 4-stimulated Akt-Erk-PLA2 signalling. PLoS ONE, 12 (11). e0186981. ISSN 1932-6203 doi: https://doi.org/10.1371/journal.pone.0186981

Ravishankar, D., Salamah, M., Attina, A., Pothi, R., Vallance, T. M., Javed, M., Williams, H. F., Alzahrani, E. M. S., Kabova, E., Vaiyapuri, R., Shankland, K., Gibbins, J., Strohfeldt, K., Greco, F., Osborn, H. M. I. and Vaiyapuri, S. (2017) Ruthenium-conjugated chrysin analogues modulate platelet activity, thrombus formation and haemostasis with enhanced efficacy. Scientific Reports, 7. 5738. ISSN 2045-2322 doi: https://doi.org/10.1038/s41598-017-05936-3

Moraes, L. A., Unsworth, A. J., Vaiyapuri, S., Ali, M. S., Sasikumar, P., Sage, T., Flora, G. D., Bye, A. P., Kriek, N., Dorchies, E., Molendi-Coste, O., Dombrowicz, D., Staels, B., Bishop-Bailey, D. and Gibbins, J. M. (2016) Farnesoid X Receptor and its ligands inhibit the function of platelets. Arteriosclerosis Thrombosis and Vascular Biology, 36 (12). pp. 2324-2333. ISSN 1524-4636 doi: https://doi.org/10.1161/ATVBAHA.116.308093

Crescente, M., Pluthero, F. G., Li, L., Lo, R. W., Walsh, T. G., Schenk, M. P., Holbrook, L. M., Loureiro, S., Ali, M. S., Vaiyapuri, S., Falet, H., Jones, I. M., Poole, A. W., Kahr, W. H. A. and Gibbins, J. M. (2016) Intracellular trafficking, localization, and mobilization of platelet-borne thiol isomerases. Arteriosclerosis Thrombosis and Vascular Biology, 36 (6). pp. 1164-1173. ISSN 1079-5642 doi: https://doi.org/10.1161/ATVBAHA.116.307461

Bye, A. P., Unsworth, A. J. and Gibbins, J. M. (2016) Platelet signaling: a complex interplay between inhibitory and activatory networks. Journal of Thrombosis and Haemostasis, 14 (5). pp. 918-930. ISSN 1538-7933 doi: https://doi.org/10.1111/jth.13302

Gibbins, J. M. (2016) Platelets stop us leaking. Blood, 127 (12). pp. 1528-1529. ISSN 0006-4971 doi: https://doi.org/10.1182/blood-2016-01-692186

Mazet, F., Dunster, J. L., Jones, C. I., Vaiyapuri, S., Tindall, M. J., Fry, M. J. and Gibbins, J. M. (2015) A high-density immunoblotting methodology for quantification of total protein levels and phosphorylation modifications. Scientific Reports, 5. 16995. ISSN 2045-2322 doi: https://doi.org/10.1038/srep16995

Wright, B., Watson, K. A., McGuffin, L. J., Lovegrove, J. and Gibbins, J. M. (2015) GRID and docking analyses reveal a molecular basis for flavonoid inhibition of src-family kinase activity. Journal of Nutritional Biochemistry, 26 (11). pp. 1156-1165. ISSN 0955-2863 doi: https://doi.org/10.1016/j.jnutbio.2015.05.004

Bye, A. P., Unsworth, A. J., Vaiyapuri, S., Stainer, A. R., Fry, M. J. and Gibbins, J. M. (2015) Ibrutinib inhibits platelet integrin αIIbβ3 outside-in signaling and thrombus stability but not adhesion to collagen. Arteriosclerosis Thrombosis and Vascular Biology, 35 (11). pp. 2326-2335. ISSN 1524-4636 doi: https://doi.org/10.1161/ATVBAHA.115.306130

Dunster, J. L., Mazet, F., Fry, M. J., Gibbins, J. M. and Tindall, M. J. (2015) Regulation of early steps of GPVI signal transduction by phosphatases: a systems biology approach. PLoS Computational Biology, 11 (11). e1004589. ISSN 1553-734X doi: https://doi.org/10.1371/journal.pcbi.1004589

Tannetta, D. S., Hunt, K., Jones, C. I., Davidson, N., Coxon, C. H., Ferguson, D., Redman, C. W., Gibbins, J. M., Sargent, I. L. and Tucker, K. L. (2015) Syncytiotrophoblast extracellular vesicles from pre-eclampsia placentas differentially affect platelet function. PLoS ONE, 10 (11). e0142538. ISSN 1932-6203 doi: https://doi.org/10.1371/journal.pone.0142538

Vaiyapuri, S., Roweth, H., Ali, M., Unsworth, A., Stainer, A., Flora, G., Crescente, M., Jones, C., Moraes, L. and Gibbins, J. (2015) Pharmacological actions of nobiletin in the modulation of platelet function. British Journal of Pharmacology, 172 (16). pp. 4133-4145. ISSN 0007-1188 doi: https://doi.org/10.1111/bph.13191

Vaiyapuri, S., Flora, G. D. and Gibbins, J. M. (2015) Gap junctions and connexin hemichannels in the regulation of haemostasis and thrombosis. Biochemical Society Transactions, 43 (3). pp. 489-494. ISSN 1470-8752 doi: https://doi.org/10.1042/BST20150055

Vaiyapuri, S., Sage, T., Rana, R. H., Schenk, M. P., Ali, M. S., Unsworth, A. J., Jones, C. I., Stainer, A. R., Kriek, N. K., Moraes, L. A. and Gibbins, J. (2015) EphB2 regulates contact-dependent and independent signalling to control platelet function. Blood, 125 (4). pp. 720-730. ISSN 0006-4971 doi: https://doi.org/10.1182/blood-2014-06-585083

Jones, C. I., Sage, T., Moraes, L. A., Vaiyapuri, S., Hussain, U., Tucker, K. L., Barrett, N. E. and Gibbins, J. M. (2014) Platelet endothelial cell adhesion molecule-1 inhibits platelet response to thrombin and von Willebrand factor by regulating the internalization of glycoprotein Ib via AKT/glycogen synthase kinase-3/dynamin and integrin αIIbβ3. Arteriosclerosis Thrombosis and Vascular Biology, 34 (9). pp. 1968-1976. ISSN 1079-5642 doi: https://doi.org/10.1161/ATVBAHA.114.304097

Jones, C. I., Tucker, K. L., Sasikumar, P., Sage, T., Kaiser, W. J., Moore, C., Emerson, M. and Gibbins, J. M. (2014) Integrin-linked kinase regulates the rate of platelet activation and is essential for the formation of stable thrombi. Journal of Thrombosis and Haemostasis, 12 (8). pp. 1342-1352. ISSN 1538-7933 doi: https://doi.org/10.1111/jth.12620

Taylor, L., Vasudevan, S. R., Jones, C. I., Gibbins, J. M., Churchill, G. C., Campbell, R. D. and Coxon, C. H. (2014) Discovery of novel GPVI receptor antagonists by structure-based repurposing. PLoS ONE, 9 (6). e101209. ISSN 1932-6203 doi: https://doi.org/10.1371/journal.pone.0101209

Dannoura, A., Giraldo, A., Pereira, I., Gibbins, J., Dash, P., Bicknell, K. and Brooks, G. (2014) Ibuprofen inhibits migration and proliferation of human coronary artery smooth muscle cells by inducing a differentiated phenotype: role of peroxisome proliferator-activated receptor y. Journal of Pharmacy and Pharmacology, 66 (6). pp. 779-792. ISSN 0022-3573 doi: https://doi.org/10.1111/jphp.12203

Ambily, A., Kaiser, W. J., Pierro, C., Chamberlain, E. V., Li, Z., Jones, C. I., Kassouf, N., Gibbins, J. M. and Authi, K. S. (2014) The role of plasma membrane STIM1 and Ca(2+)entry in platelet aggregation. STIM1 binds to novel proteins in human platelets. Cellular Signalling, 26 (3). pp. 502-511. ISSN 0898-6568 doi: https://doi.org/10.1016/j.cellsig.2013.11.025

Waller, A. K., Sage, T., Kumar, C., Carr, T., Gibbins, J. M. and Clarke, S. R. (2013) Staphylococcus aureus lipoteichoic acid inhibits platelet activation and thrombus formation via the Paf receptor. Journal of Infectious Diseases, 208 (12). pp. 2046-2057. ISSN 1537-6613 doi: https://doi.org/10.1093/infdis/jit398

Wright, B., Spencer, J. P. E., Lovegrove, J. A. and Gibbins, J. M. (2013) Flavonoid inhibitory pharmacodynamics on platelet function in physiological environments. Food & Function, 4 (12). pp. 1803-1810. ISSN 2042-650X doi: https://doi.org/10.1039/C3FO60272A

Wright, B., Tindall, M. J., Lovegrove, J. A. and Gibbins, J. M. (2013) Investigating flavonoids as molecular templates for the design of small-molecule inhibitors of cell signaling. Journal of Food Science, 78 (12). N1921-N1928. ISSN 1750-3841 doi: https://doi.org/10.1111/1750-3841.12293

Vaiyapuri, S., Ali, M. S., Moraes, L. A., Sage, T., Lewis, K. R., Jones, C. I. and Gibbins, J. M. (2013) Tangeretin regulates platelet function through inhibition of phosphoinositide 3-Kinase and cyclic nucleotide signaling. Arteriosclerosis Thrombosis and Vascular Biology, 33 (12). pp. 2740-2749. ISSN 1079-5642 doi: https://doi.org/10.1161/ATVBAHA.113.301988

Vaiyapuri, S., Vaiyapuri, R., Ashokan, R., Ramasamy, K., Nattamaisundar, K., Jeyaraj, A., Chandran, V., Gajjeraman, P., Baksh, M. F., Gibbins, J. M. and Hutchinson, E. G. (2013) Snakebite and its socio-economic impact on the rural population of Tamil Nadu, India. PLoS ONE, 8 (11). e80090. ISSN 1932-6203 doi: https://doi.org/10.1371/journal.pone.0080090

Gibbins, J. (2013) Platelets using proteins creatively. Blood, 122 (22). pp. 3553-3554. ISSN 0006-4971 doi: https://doi.org/10.1182/blood-2013-09-527663

Moraes, L. A., Vaiyapuri, S., Sasikumar, P., Ali, M. S., Kriek, N. K., Sage, T. and Gibbins, J. M. (2013) Antithrombotic actions of statins involve PECAM-1 signalling. Blood, 122 (18). pp. 3188-3196. ISSN 0006-4971 doi: https://doi.org/10.1182/blood-2013-04-491845

Vaiyapuri, S., Moraes, L. A., Sage, T., Ali, M. S., Lewis, K. R., Mayhaut-Smith, M. P., Oviedo-Orta, E., Simon, A. M. and Gibbins, J. M. (2013) Connexin40 regulates platelet function. Nature Communications, 4. pp. 2564-2572. ISSN 2041-1723 doi: https://doi.org/10.1038/ncomms3564

Kim, K., Hahm, E., Li, J., Holbrook, L.-M., Sasikumar, P., Stanley, R. G., Ushio-Fukai, M., Gibbins, J. M. and Cho, J. (2013) Platelet protein disulfide isomerase is required for thrombus formation but not essential for hemostasis in mice. Blood, 122 (6). pp. 1052-1061. ISSN 0006-4971 doi: https://doi.org/10.1182/blood-2013-03-492504

Wright, B., Stanley, R. G., Kaiser, W. J. and Gibbins, J. M. (2013) The integration of proteomics and systems approaches to map regulatory mechanisms underpinning platelet function. Proteomics, Clinical Applications, 7 (1-2). pp. 144-154. ISSN 1862-8354 doi: https://doi.org/10.1002/prca.201200095

Wright, B., Spencer, J. P. E., Lovegrove, J. A. and Gibbins, J. (2013) Insights into dietary flavonoids as molecular templates for the design of anti-platelet drugs. Cardiovascular Research, 97 (1). pp. 13-22. ISSN 0008-6363 doi: https://doi.org/10.1093/cvr/cvs304

Vaiyapuri, S., Thiyagarajan, N., Hutchinson, E. G. and Gibbins, J. M. (2012) Sequence and phylogenetic analysis of viper venom serine proteases. Bioinformation, 8 (16). pp. 763-772. ISSN 0973-2063

Vaiyapuri, S., Hutchinson, E. G., Ali, M. S., Dannoura, A., Stanley, R. G., Harrison, R. A., Bicknell, A. B. and Gibbins, J. M. (2012) Rhinocetin, a venom-derived integrin-specific antagonist inhibits collagen-induced platelet and endothelial cell functions. The Journal of Biological Chemistry, 287 (31). pp. 26235-26244. ISSN 1083-351X doi: https://doi.org/10.1074/jbc.M112.381483

Vaiyapuri, S., Jones, C. I., Sasikumar, P., Moraes, L. A., Munger, S. J., Wright, J. R., Ali, M. S., Sage, T., Kaiser, W. J., Tucker, K. L., Stain, C. J., Bye, A. P., Jones, S., Oviedo-Orta, E., Simon, A. M., Mahaut-Smith, M. P. and Gibbins, J. M. (2012) Gap junctions and connexin hemichannels underpin hemostasis and thrombosis. Circulation, 125 (20). pp. 2479-2491. ISSN 0009-7322 doi: https://doi.org/10.1161/CIRCULATIONAHA.112.101246

Gibbins, J. (2012) JAMming the signals. Blood, 119 (14). pp. 3197-3198. ISSN 1528-0020 doi: https://doi.org/10.1182/blood-2012-02-409060

Holbrook, L.-M., Sasikumar, P., Stanley, R. G., Simmonds, A. D., Bicknell, A. B. and Gibbins, J. M. (2012) The platelet-surface thiol isomerase enzyme ERp57 modulates platelet function. Journal of Thrombosis and Haemostasis, 10 (2). pp. 278-288. ISSN 1538-7933 doi: https://doi.org/10.1111/j.1538-7836.2011.04593.x

Coxon, C. H., Lewis, A. M., Sadler, A. J., Vasudevan, S. R., Thomas, A., Dundas, K. A., Taylor, L., Campbell, R.D., Gibbins, J. M., Churchill, G. C. and Tucker, K. L. (2012) NAADP regulates human platelet function. Biochemical Journal, 441 (1). pp. 435-442. ISSN 0264-6021 doi: https://doi.org/10.1042/BJ20111175

Mitchell, H. L., Gibbins, J. M., Griffin, B. A., Lovegrove, J. A., Stowell, J. D. and Foot, E. (2012) Food and Health Forum meeting - nutritional approaches to cardiovascular health: workshop report. Nutrition Bulletin, 37 (3). pp. 270-284. ISSN 1471-9827 doi: https://doi.org/10.1111/j.1467-3010.2012.01984.x

Jones, C. I., Moraes, L. A. and Gibbins, J. M. (2012) Regulation of platelet biology by platelet endothelial cell adhesion molecule-1. Platelets, 23 (5). pp. 331-335. ISSN 1369-1635 doi: https://doi.org/10.3109/09537104.2011.626091

Bertling, A., Niemann, S., Hussain, M., Holbrook, L., Stanley, R. G., Brodde, M. F., Pohl, S., Schifferdecker, T., Roth, J., Jurk, K., Müller, A., Lahav, J., Peters, G., Heilmann, C., Gibbins, J. M. and Kehrel, B. E. (2012) Staphylococcal extracellular adherence protein induces platelet activation by stimulation of thiol isomerases. Arteriosclerosis Thrombosis and Vascular Biology, 32. pp. 1979-1990. ISSN 1079-5642 doi: https://doi.org/10.1161/ATVBAHA.112.246249

Wright, B., Stanley, R. G., Kaiser, W. J., Mills, D. J. and Gibbins, J. M. (2011) Analysis of protein networks in resting and collagen receptor (GPVI)-stimulated platelet sub-proteomes. Proteomics, 11 (23). pp. 4588-4592. ISSN 1615-9853 doi: https://doi.org/10.1002/pmic.201100410

Vaiyapuri, S., Wagstaff, S. C., Harrison, R. A., Gibbins, J. M. and Hutchinson, G. (2011) Evolutionary analysis of novel serine proteases in the venom gland transcriptome of Bitis gabonica rhinoceros. PLoS ONE, 6 (6). e21532. ISSN 1932-6203 doi: https://doi.org/10.1371/journal.pone.0021532

Spyridon, M., Moraes, L. A., Jones, C. I., Sage, T., Sasikumar, P., Bucci, G. and Gibbins, J. M. (2011) LXR as a novel antithrombotic target. Blood, 117 (21). pp. 5751-5761. ISSN 1528-0020 doi: https://doi.org/10.1182/blood-2010-09-306142

Moraes, L. A., Barrett, N. E., Jones, C., Holbrook, L. M., Spyridon, M., Sage, T., Newman, D. K. and Gibbins, J. M. (2010) Platelet endothelial cell adhesion molecule-1 regulates collagen-stimulated platelet function by modulating the association of phosphatidylinositol 3-kinase with Grb-2-associated binding protein-1 and linker for activation of T cells. Journal of Thrombosis and Haemostasis, 8 (11). pp. 2530-2541. ISSN 1538-7933 doi: https://doi.org/10.1111/j.1538-7836.2010.04025.x

Glen, A., Evans, C. A., Gan, C. S., Cross, S. S., Hamdy, F. C., Gibbins, J., Lippitt, J., Eaton, C. L., Noirel, J., Wright, P. C. and Rehman, I. (2010) Eight-plex iTRAQ analysis of variant metastatic human prostate cancer cells identifies candidate biomarkers of progression: an exploratory study. The Prostate, 70 (12). pp. 1313-1332. ISSN 1097-0045 doi: https://doi.org/10.1002/pros.21167

Vaiyapuri, S., Wagstaff, S. C., Watson, K. A., Harrison, R. A., Gibbins, J. M. and Hutchinson, E. G. (2010) Purification and functional characterisation of rhiminopeptidase A, a novel aminopeptidase from the venom of Bitis gabonica rhinoceros. PLoS Neglected Tropical Diseases, 4 (8). e796. ISSN 1935-2735 doi: https://doi.org/10.1371/journal.pntd.0000796

Wright, B., Gibson, T., Spencer, J., Lovegrove, J. A. and Gibbins, J. M. (2010) Platelet-mediated metabolism of the common dietary flavonoid, quercetin. PLoS ONE, 5 (3). e9673. ISSN 1932-6203 doi: https://doi.org/10.1371/journal.pone.0009673

Moraes, L. A., Spyridon, M., Kaiser, W. J., Jones, C., Sage, T., Atherton, R. E. and Gibbins, J. M. (2010) Non-genomic effects of PPARgamma ligands: inhibition of GPVI-stimulated platelet activation. Journal of Thrombosis and Haemostasis, 8 (3). pp. 577-587. ISSN 1538-7933 doi: https://doi.org/10.1111/j.1538-7836.2009.03732.x

Vaiyapuri, S., Harrison, R. A., Bicknell, A., Gibbins, J. M. and Hutchinson, E. G. (2010) Purification and functional characterisation of Rhinocerase, a novel serine protease from the venom of Bitis gabonica rhinoceros. PLoS ONE, 5 (3). e9687. ISSN 1932-6203 doi: https://doi.org/10.1371/journal.pone.0009687

Wright, B., Moraes, L. A., Kemp, C. F., Mullen, W., Crozier, A., Lovegrove, J. A. and Gibbins, J. M. (2010) A structural basis for the inhibition of collagen-stimulated platelet function by quercetin and structurally related flavonoids. British Journal of Pharmacology, 159. pp. 1312-1325. ISSN 1476-5381 doi: https://doi.org/10.1111/j.1476-5381.2009.00632.x

Holbrook, L. M., Watkins, N. A., Simmonds, A. D., Jones, C., Ouwehand, W. H. and Gibbins, J. M. (2010) Platelets release novel thiol isomerase enzymes which are recruited to the cell surface following activation. British Journal of Haematology, 148 (4). pp. 627-637. ISSN 0007-1048 doi: https://doi.org/10.1111/j.1365-2141.2009.07994.x

Jones, C. I., Garner, S. F., Moraes, L. A., Kaiser, W. J., Rankin, A., Bloodomics Consortium, , Ouwehand, W. H., Goodall, A. H. and Gibbins, J. M. (2009) PECAM-1 expression and activity negatively regulate multiple platelet signaling pathways. FEBS Letters, 583 (22). pp. 3618-3624. ISSN 0014-5793 doi: https://doi.org/10.1016/j.febslet.2009.10.037

Tucker, K. L., Kaiser, W. J., Bergeron, A. L., Hu, H. B., Dong, J. F., Tan, T. H. and Gibbins, J. M. (2009) Proteomic analysis of resting and thrombin-stimulated platelets reveals the translocation and functional relevance of HIP-55 in platelets. Proteomics, 9 (18). pp. 4340-4354. ISSN 1615-9853 doi: https://doi.org/10.1002/pmic.200900024

Gibbins, J. M. (2009) Tweaking the gain on platelet regulation: The tachykinin connection. Atherosclerosis, 206 (1). pp. 1-7. ISSN 0021-9150 doi: https://doi.org/10.1016/j.atherosclerosis.2008.12.010

Kaiser, W. J., Holbrook, L. M., Tucker, K. L., Stanley, R. G. and Gibbins, J. M. (2009) A functional proteomic method for the enrichment of peripheral membrane proteins reveals the collagen binding protein Hsp47 is exposed on the surface of activated human platelets. Journal of Proteome Research, 8 (6). pp. 2903-2914. ISSN 1535-3893 doi: https://doi.org/10.1021/pr900027j

Barrett, N. E., Holbrook, L., Jones, S., Kaiser, W. J., Moraes, L. A., Rana, R., Sage, T., Stanley, R. G., Tucker, K. L., Wright, B. and Gibbins, J. M. (2008) Future innovations in anti-platelet therapies. British Journal of Pharmacology, 154 (5). pp. 918-939. ISSN 0007-1188 doi: https://doi.org/10.1038/bjp.2008.151

Jones, S., Tucker, K. L., Sage, T., Kaiser, W. J., Barrett, N. E., Lowry, P. J., Zimmer, A., Hunt, S. P., Emerson, M. and Gibbins, J. M. (2008) Peripheral tachykinins and the neurokinin receptor NK1 are required for platelet thrombus formation. Blood, 111 (2). pp. 605-612. ISSN 0006-4971 doi: https://doi.org/10.1182/blood-2007-07-103424

Tucker, K. L., Sage, T., Stevens, J. M., Jordan, P. A., Jones, S., Barrett, N. E., St-Arnaud, R., Frampton, J., Dedhar, S. and Gibbins, J. M. (2008) A dual role for integrin-linked kinase in platelets: regulating integrin function and alpha-granule secretion. Blood, 112 (12). pp. 4523-4531. ISSN 0006-4971 doi: https://doi.org/10.1182/blood-2008-03-148502

Jones, S. and Gibbins, J. M. (2008) The neurokinin 1 receptor: a potential new target for anti-platelet therapy? Current Opinion in Pharmacology, 8 (2). pp. 114-119. ISSN 1471-4892 doi: https://doi.org/10.1016/j.coph.2008.01.004

Guerrero, J. A., Navarro-Nunez, L., Lozano, M. L., Martinez, C., Vicente, V., Gibbins, J. M. and Rivera, J. (2007) Flavonoids inhibit the platelet TxA(2) signalling pathway and antagonize TxA(2) receptors (TP) in platelets and smooth muscle cells. British Journal of Clinical Pharmacology, 64 (2). pp. 133-144. ISSN 0306-5251 doi: https://doi.org/10.1111/j.1365-2125.2007.02881.x

Gumireddy, K., Sun, F. X., Klein-Szanto, A. J., Gibbins, J. M., Gimotty, P. A., Saunders, A. J., Schultz, P. G. and Huang, Q. H. (2007) In vivo selection for metastasis promoting genes in the mouse. Proceedings of the National Academy of Sciences of the United States of America, 104 (16). pp. 6696-6701. ISSN 0027-8424 doi: https://doi.org/10.1073/pnas.0701145104

Moraes, L. A., Bishop-Bailey, D. and Gibbins, J. M. (2007) Non-genomic signalling of the retinoic X receptor through inhibition of Gq signalling in human platelets. Heart, 93 (11). pp. 371-374. ISSN 1355-6037

Moraes, L. A., Swales, K. E., Wray, J. A., Damazo, A., Gibbins, J. M., Warner, T. D. and Bishop-Bailey, D. (2007) Nongenomic signaling of the retinoid X receptor through binding and inhibiting Gq in human platelets. Blood, 109 (9). pp. 3741-3744. ISSN 0006-4971 doi: https://doi.org/10.1182/blood-2006-05-022566

Hubbard, G. P., Wolffram, S., de Vos, R., Bovy, A., Gibbins, J. M. and Lovegrove, J. A. (2006) Ingestion of onion soup high in quercetin inhibits platelet aggregation and essential components of the collagen-stimulated platelet activation pathway in man: a pilot study. British Journal of Nutrition, 96 (3). pp. 482-488. ISSN 0007-1145

Jordan, P. A. and Gibbins, J. M. (2006) Extracellular disulfide exchange and the regulation of cellular function. Antioxidants & Redox Signaling, 8 (3-4). pp. 312-324. ISSN 1523-0864

Falati, S., Patil, S., Gross, P. L., Stapleton, M., Merrill-Skoloff, G., Barrett, N. E., Pixton, K. L., Weiler, H., Cooley, B., Newman, D. K., Newman, P. J., Furie, B. C., Furie, B. and Gibbins, J. M. (2006) Platelet PECAM-1 inhibits thrombus formation in vivo. Blood, 107 (2). pp. 535-541. ISSN 0006-4971 doi: https://doi.org/10.1182/blood-2005-04-1512

Patel, B., Sharifi, M., Milward, A. D., Oberprieler, N. G., Gibbins, J. M., Parkin, S. and Naseem, K. M. (2006) Platelet nitric oxide synthase is activated by tyrosine dephosphorylation: possible role for SHP-1 phosphatase. Journal of Thrombosis and Haemostasis, 4 (11). pp. 2423-2432. ISSN 1538-7933 doi: https://doi.org/10.1111/j.1538-7836.2006.02160.x

Jordan, P. A., Stevens, J. M., Hubbard, G. P., Barrett, N. E., Sage, T., Authi, K. S. and Gibbins, J. M. (2005) A role for the thiol isomerase. protein ERP5 in platelet function. Blood, 105 (4). pp. 1500-1507. ISSN 0006-4971 doi: https://doi.org/10.1182/blood-2004-02-0608

Hubbard, G.P., Wolffram, S., Lovegrove, J.A. and Gibbins, J. M. (2004) Ingestion of quercetin inhibits platelet aggregation and essential components of the collagen-stimulated platelet activation pathway in humans. Journal of Thrombosis and Haemostasis, 2 (12). pp. 2138-2145. ISSN 1538-7933 doi: https://doi.org/10.1111/j.1538-7836.2004.01067.x

Coffey, M.J., Jarvis, G.E., Gibbins, J. M., Coles, B., Barrett, N.E., Wylie, O.R.E. and O'Donnell, V.B. (2004) Platelet 12-lipoxygenase activation via glycoprotein VI: involvement of multiple signaling pathways in agonist control of H(P)ETE synthesis. Circulation Research, 94 (12). pp. 1598-1605. ISSN 0009-7330 doi: https://doi.org/10.1161/01.RES.0000132281.78948.65

Gibbins, J. M. (2004) Platelet adhesion signalling and the regulation of thrombus formation. Journal of Cell Science, 117 (16). pp. 3415-3425. ISSN 0021-9533 doi: https://doi.org/10.1242/jcs.01325

Jones, M. L., Craik, J. D., Gibbins, J. M. and Poole, A. W. (2004) Regulation of SHP-1 tyrosine phosphatase in human platelets by serine phosphorylation at its C terminus. The Journal of Biological Chemistry, 279 (39). pp. 40475-40483. ISSN 1083-351X doi: https://doi.org/10.1074/jbc.M402970200

Batuwangala, T., Leduc, M., Gibbins, J. M., Bon, C. and Jones, E. Y. (2004) Structure of the snake-venom toxin convulxin. Acta Crystallographica Section D- Biological Crystallography, 60 (1). pp. 46-53. ISSN 0907-4449 doi: https://doi.org/10.1107/s0907444903021620

Gibbins, J. M. (2004) Study of tyrosine kinases and protein tyrosine phosphorylation. Methods in Molecular Biology, 273. pp. 153-168. ISSN 1064-3745 doi: https://doi.org/10.1385/1-59259-783-1:153

Graham, G. J., Stevens, J. M., Page, N. M., Grant, A. D., Brain, S. D., Lowry, P. J. and Gibbins, J. M. (2004) Tachykinins regulate the function of platelets. Blood, 104 (4). pp. 1058-1065. ISSN 0006-4971 doi: https://doi.org/10.1182/blood-2003-11-3979

Gibbins, J. M. (2004) Techniques for analysis of proteins by SDS-polyacrylamide gel electrophoresis and Western blotting. Methods in Molecular Biology, 273. pp. 139-152. ISSN 1064-3745 doi: https://doi.org/10.1385/1592597831

Stevens, J. M., Jordan, P. A., Sage, T. and Gibbins, J. M. (2004) The regulation of integrin-linked kinase in human platelets: evidence for involvement in the regulation of integrin alpha(2)beta(1). Journal of Thrombosis and Haemostasis, 2 (8). pp. 1443-1452. ISSN 1538-7933 doi: https://doi.org/10.1111/j.1538-7836.2004.00870.x

Polanowska-Grabowska, R., Gibbins, J. M. and Gear, A. R. L. (2003) Platelet adhesion to collagen and collagen-related peptide under flow. Roles of the alpha(2)beta(1) integrin, GPVI, and Src tyrosine kinases. Arteriosclerosis Thrombosis and Vascular Biology, 23 (10). pp. 1934-1940. ISSN 1079-5642 doi: 01.ATV.0000086937.46974.70v1

Hubbard, G.P., Stevens, J.M., Cicmil, M., Sage, T., Jordan, P.A., Williams, C.M., Lovegrove, J.A. and Gibbins, J.M. (2003) Quercetin inhibits collagen-stimulated platelet activation through inhibition of multiple components of the glycoprotein VI signaling pathway. Journal of Thrombosis and Haemostasis, 1 (5). pp. 1079-1088. ISSN 1538-7933 doi: https://doi.org/10.1046/j.1538-7836.2003.00212.x

Barry, F. A., Graham, G. J., Fry, M. J. and Gibbins, J. M. (2003) Regulation of glycogen synthase kinase 3 in human platelets: a possible role in platelet function? FEBS Letters, 553 (1-2). pp. 173-178. ISSN 0014-5793 doi: https://doi.org/10.1016/s0014-5793(03)01015-9

Hubbard, G. P., Wolffram, S., Lovegrove, J. A. and Gibbins, J. M. (2003) The role of polyphenolic compounds in the diet as inhibitors of platelet function. Proceedings of the Nutrition Society, 62 (2). pp. 469-478. ISSN 0029-6651 doi: https://doi.org/10.1079/pns2003253

Gibbins, J. M. (2002) The negative regulation of platelet function: extending the role of the ITIM. Trends in Cardiovascular Medicine, 12 (5). pp. 213-219. ISSN 1050-1738

Barry, F. A. and Gibbins, J. M. (2002) Protein kinase B is regulated in platelets by the collagen receptor glycoprotein VI. The Journal of Biological Chemistry, 277 (15). pp. 12874-12878. ISSN 1083-351X doi: https://doi.org/10.1074/jbc.M200482200

Cicmil, M., Thomas, J., Leduc, M., Bon, C. and Gibbins, J. (2002) Platelet endothelial cell adhesion molecule-1 signaling inhibits the activation of human platelets. Blood, 99 (1). pp. 137-144. ISSN 0006-4971 doi: https://doi.org/10.1182/blood.V99.1.137

Berlanga, O., Bobe, R., Becker, M., Murphy, G., Leduc, M., Bon, C., Barry, F., Gibbins, J., Garcia, P., Frampton, J. and Watson, S. P. (2000) Expression of the collagen receptor glycoprotein VI during megakaryocyte differentiation. Blood, 96 (8). pp. 2740-2745. ISSN 0006-4971

Cicmil, M., Thomas, J. M., Sage, T., Barry, F. A., Leduc, M., Bon, C. and Gibbins, J. (2000) Collagen, convulxin, and thrombin stimulate aggregation-independent tyrosine phosphorylation of CD31 in platelets. Evidence for the involvement of Src family kinases. The Journal of biological chemistry, 275 (35). pp. 27339-27347. ISSN 0021-9258 doi: https://doi.org/10.1074/jbc.M003196200

Mountford, J. C., Melford, S. K., Bunce, C. M., Gibbins, J. and Watson, S. P. (1999) Collagen or collagen-related peptide cause (Ca2+)i elevation and increased tyrosine phosphorylation in human megakaryocytes. Thrombosis and haemostasis, 82 (3). pp. 1153-1159. ISSN 0340-6245

Gibbins, J., Briddon, S., Shutes, A., van Vugt, M. J., van de Winkel, J. G., Saito, T. and Watson, S. P. (1998) The p85 subunit of phosphatidylinositol 3-kinase associates with the Fc receptor gamma-chain and linker for activitor of T cells (LAT) in platelets stimulated by collagen and convulxin. The Journal of biological chemistry, 273 (51). pp. 34437-34443. ISSN 0021-9258

Watson, S. P. and Gibbins, J. (1998) Collagen receptor signalling in platelets: extending the role of the ITAM. Immunology today, 19 (6). pp. 260-264. ISSN 0167-5699

Gibbins, J., Okuma, M., Farndale, R., Barnes, M. and Watson, S. P. (1997) Glycoprotein VI is the collagen receptor in platelets which underlies tyrosine phosphorylation of the Fc receptor gamma-chain. FEBS letters, 413 (2). pp. 255-259. ISSN 0014-5793

Poole, A., Gibbins, J., Turner, M., van Vugt, M. J., van de Winkel, J. G., Saito, T., Tybulewicz, V. L. and Watson, S. P. (1997) The Fc receptor gamma-chain and the tyrosine kinase Syk are essential for activation of mouse platelets by collagen. The EMBO journal, 16 (9). pp. 2333-2341. ISSN 0261-4189

Asselin, J., Gibbins, J., Achison, M., Lee, Y. H., Morton, L. F., Farndale, R. W., Barnes, M. J. and Watson, S. P. (1997) A collagen-like peptide stimulates tyrosine phosphorylation of syk and phospholipase C gamma2 in platelets independent of the integrin alpha2beta1. Blood, 89 (4). pp. 1235-1242. ISSN 0006-4971

Gibbins, J., Woods, R. and Lowry, P. (1996) Affinity purification of 61- and 65-kDa rat brain corticotropin-releasing factor receptors and receptor-associated G proteins. The international journal of biochemistry & cell biology, 28 (9). pp. 1017-1029. ISSN 1357-2725

Gibbins, J., Asselin, J., Farndale, R., Barnes, M., Law, C. L. and Watson, S. P. (1996) Tyrosine phosphorylation of the Fc receptor gamma-chain in collagen-stimulated platelets. The Journal of biological chemistry, 271 (30). pp. 18095-18099. ISSN 0021-9258

Robinson, A., Gibbins, J., Rodríguez-Liñares, B., Finan, P. M., Wilson, L., Kellie, S., Findell, P. and Watson, S. P. (1996) Characterization of Grb2-binding proteins in human platelets activated by Fc gamma RIIA cross-linking. Blood, 88 (2). pp. 522-530. ISSN 0006-4971

Woods, R., David, J., Baigent, S., Gibbins, J. and Lowry, P. (1996) Elevated levels of corticotrophin-releasing factor binding protein in the blood of patients suffering from arthritis and septicaemia and the presence of novel ligands in synovial fluid. British journal of rheumatology, 35 (2). pp. 120-124. ISSN 0263-7103

Woods, R., Kennedy, K. M., Gibbins, J., Behan, D., Vale, W. and Lowry, P. (1994) Corticotropin-releasing factor binding protein dimerizes after association with ligand. Endocrinology, 135 (2). pp. 768-773. ISSN 0013-7227

Book or Report Section

Dunster, J. L., Panteleev, M. A., Gibbins, J. M. and Sveshnikova, A. N. (2018) Mathematical techniques for understanding platelet regulation and the development of new pharmacological approaches. In: Gibbins, J. M. and Mahaut-Smith, M. (eds.) Platelets and Megakaryocytes: Volume 4, Advanced Protocols and Perspectives. Methods in Molecular Biology, 1812. Humana Press, New York, pp. 255-279. ISBN 9781493985845 doi: https://doi.org/10.1007/978-1-4939-8585-2_15

Bye, A. P., Unsworth, A. J. and Gibbins, J. M. (2018) Screening and high-throughput platelet assays. In: Gibbins, J. M. and Mahaut-Smith, M. (eds.) Platelets and Megakaryocytes: Volume 4, Advanced Protocols and Perspectives. Humana Press, New York, pp. 81-94. ISBN 9781493985845 doi: https://doi.org/10.1007/978-1-4939-8585-2_5

Vaiyapuri, S., Sunagar, K., Gibbins, J., Jackson, T. N. W., Reeks, T. and Fry, B. G. (2015) Kallikrein enzymes. In: Fry, B. (ed.) Venomous reptiles and their toxins: evolution, pathophysiology and biodiscovery. Oxford University Press, New York, pp. 267-280. ISBN 9780199309399

Stanley, R., Tucker, K., Barrett, N. E. and Gibbins, J. (2011) Platelets and their role in thrombotic and cardiovascular disease: the impact of proteomic analysis. In: Garcia, A. and Senis, Y. (eds.) Platelet Proteomics: Principles, Analysis and Applications. Mass Spectrometry . Wiley, pp. 3-26. ISBN 9780470463376

Tucker, K. L., Sage, T. and Gibbins, J. M. (2011) Clot retraction. In: Gibbins, J. M. and Mahaut-Smith, M. P. (eds.) Platelets and Megakaryocytes. vol. 3, Additional Protocols and Perspectives. Methods in Molecular Biology, vol. 788. Humana Press, pp. 101-108. ISBN 9781617793066

Jones, C. I., Barrett, N. E., Moraes, L. A., Gibbins, J. M. and Jackson, D. E. (2011) Endogenous inhibitory mechanisms and the regulation platelet function. In: Gibbins, J. and Mahaut-Smith, M. (eds.) Platelets and Megakaryocytes. vol. 3, Additional Protocols and Perspectives. Methods in Molecular Biology, vol. 788. Humana Press, pp. 341-366. ISBN 9781617793066

Book

Gibbins, J. M. and Mahaut-Smith, M., eds. (2018) Platelets and Megakaryocytes. Volume 4, Advanced Protocols and Perspectives. Methods in Molecular Biology, 1812. Humana Press, pp304. ISBN 9781493985845 doi: https://doi.org/10.1007/978-1-4939-8585-2