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Items where Author is "Vaiyapuri, Professor Sakthi"

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Senthilkumaran, S., Sampath, S., Almeida, J. R. ORCID: https://orcid.org/0000-0002-4637-4468, Williams, J., Williams, H. F., Patel, K., Thirumalaikolundusubramanian, P. and Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517 (2024) Pulmonary thromboembolism following Russell’s viper bites. Toxins, 16 (5). 222. ISSN 2072-6651 doi: https://doi.org/10.3390/toxins16050222

Feijoo-Coronel, M. L., Mendes, B., Ramírez, D., Peña-Varas, C., Monteros-Silva, N. Q. E. d. l., Proaño-Bolaños, C., Oliveira, L. C. D., Lívio, D. F., Da Silva, J. A., Da Silva, J. M. S. F., Pereira, M. G. A. G., Rodrigues, M. Q. R. B., Teixeira, M. M., Granjeiro, P. A., Patel, K., Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517 and Almeida, J. R. (2024) Antibacterial and antiviral properties of Chenopodin-derived synthetic peptides. Antibiotics, 13 (1). 78. ISSN 2079-6382 doi: https://doi.org/10.3390/antibiotics13010078

Bin Haidar, H., Almeida, J. R., Williams, J., Guo, B., Bigot, A., Senthilkumaran, S., Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517 and Patel, K. (2024) Differential effects of the venoms of Russell’s viper and Indian cobra on human myoblasts. Scientific Reports, 14. 3184. ISSN 2045-2322 doi: https://doi.org/10.1038/s41598-024-53366-9

Sørensen, C. V., Almeida, J. R. ORCID: https://orcid.org/0000-0002-4637-4468, Bohn, M.-F., Torre, E. R. d., Schoffelen, S., Voldborg, B. G., Ljungars, A., Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517 and Laustsen, A. H. (2023) Discovery of a human monoclonal antibody that cross-neutralizes venom phospholipase A2s from three different snake genera. Toxicon, 234. 107307. ISSN 0041-0101 doi: https://doi.org/10.1016/j.toxicon.2023.107307

Salim, A., Williams, J., Wahab, S. A., Adeshokan, T., Almeida, J. R., Williams, H. F., Vaiyapuri, R., Senthilkumaran, S., Thirumalaikolundusubramanian, P., Patel, K., Baksh, M. F. ORCID: https://orcid.org/0000-0003-3107-8815, Lewin, M. R. and Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517 (2023) Identifying key factors contributing to treatment costs for snakebite envenoming in private tertiary healthcare settings in Tamil Nadu, India. PLoS Neglected Tropical Diseases, 17 (10). e0011699. ISSN 1935-2735 doi: https://doi.org/10.1371/journal.pntd.0011699

Senthilkumaran, S., Sampath, S., Miller, S. W., Almeida, J. R., Williams, J., Williams, H. F., Thirumalaikolundusubramanian, P., Patel, K. and Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517 (2023) Partial segmental thrombosis of the corpus cavernosum following Russell’s viper bite. Toxicon, 234. 107284. ISSN 0041-0101 doi: https://doi.org/10.1016/j.toxicon.2023.107284

Sonavane, M., Almeida, J. R. ORCID: https://orcid.org/0000-0002-4637-4468, Rajan, E., Williams, H. F., Townsend, F., Cornish, E., Mitchell, R. D., Patel, K. and Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517 (2023) Intramuscular bleeding and formation of microthrombi during skeletal muscle damage caused by a snake venom metalloprotease and a cardiotoxin. Toxins, 15 (9). 530. ISSN 2072-6651 doi: https://doi.org/10.3390/toxins15090530

Richards, N. J., Alqallaf, A., Mitchell, R. D., Parnell, A., Haidar, H. B., Almeida, J. R., Williams, J., Vijayakumar, P., Balogun, A., Matsakas, A., Trim, S. A., Patel, K. and Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517 (2023) Indian ornamental tarantula (Poecilotheria regalis) venom affects myoblast function and causes skeletal muscle damage. Cells, 12 (16). 2074. ISSN 2073-4409 doi: https://doi.org/10.3390/cells12162074

Senthilkumaran, S., Arathisenthil, S. V., Williams, J., Almeida, J. R., Williams, H. F., Rajan, E., Thirumalaikolundusubramanian, P., Patel, K. and Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517 (2023) Neutrophil-mediated erythrophagocytosis following Russell's viper (Daboia russelii) bite. Toxicon, 228. 107111. ISSN 0041-0101 doi: https://doi.org/10.1016/j.toxicon.2023.107111

Senthilkumaran, S., Patel, K., Rajan, E., Vijayakumar, P., Miller, S. W., Rucavado, A., Gilabadi, S., Sonavane, M., Richards, N. J., Williams, J., Williams, H. F., Trim, S. A., Thirumalaikolundusubramanian, P., Gutiérrez, J. M. and Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517 (2023) Peripheral arterial thrombosis following Russell’s viper bites. TH Open, 07 (02). e168-e183. ISSN 2512-9465 doi: https://doi.org/10.1055/s-0043-1769625

Williams, H. F., Moejes, K., Williams, J., Almeida, J. R. ORCID: https://orcid.org/0000-0002-4637-4468, Savania, R., Senthilkumaran, S., Patel, K. and Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517 (2023) Ashes to eye: a skilled snake handler’s experience with ophthalmic envenomation. PLoS Neglected Tropical Diseases, 17 (4). e0011264. ISSN 1935-2735 doi: https://doi.org/10.1371/journal.pntd.0011264

Senthilkumaran, S., Almeida, J. R., Williams, J., Williams, H. F., Thirumalaikolundusubramanian, P., Patel, K. and Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517 (2023) Rapid identification of bilateral adrenal and pituitary haemorrhages induced by Russell's viper envenomation results in positive patient outcome. Toxicon, 225. 107068. ISSN 0041-0101 doi: https://doi.org/10.1016/j.toxicon.2023.107068

Senthilkumaran, S., Salim, A., Almeida, J. R., Williams, J., Vijayakumar, P., Thirunavukarasu, A., Christopoulos, M. A., Williams, H. F., Thirumalaikolundusubramanian, P., Patel, K. and Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517 (2023) The effectiveness of antibiotics in managing bacterial infections on bite sites following snakebite envenomation. Toxins, 15 (3). 190. ISSN 2072-6651 doi: https://doi.org/10.3390/toxins15030190

Senthilkumaran, S., Almeida, J. R., Williams, J., Salim, A., Williams, H. F., Thirumalaikolundusubramanian, P., Patel, K. and Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517 (2023) Russell's viper envenomation induces rectus sheath haematoma. Toxicon, 224. 107037. ISSN 0041-0101 doi: https://doi.org/10.1016/j.toxicon.2023.107037

Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517, Kadam, P., Chandrasekharuni, G., Oliveira, I. S., Senthilkumaran, S., Salim, A., Patel, K., Sachett, J. d. A. G. and Pucca, M. B. (2023) Multifaceted community health education programs as powerful tools to mitigate snakebite-induced deaths, disabilities, and socioeconomic burden. Toxicon: X, 17. 100147. ISSN 2590-1710 doi: https://doi.org/10.1016/j.toxcx.2022.100147

Samy, R. P., Mackessy, S. P., Jeyasankar, A., Ponraj, M. R., Franco, O. L., Cooper, M. A., Kandasamy, M., Mohanta, T. K., Bhagavathsingh, J. and Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517 (2023) Purification of PaTx-II from the venom of Australian King Brown Snake and characterization of its antimicrobial and wound healing activities. International Journal of Molecular Sciences, 24 (5). 4359. ISSN 1422-0067 doi: https://doi.org/10.3390/ijms24054359

Williams, J. and Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517 (2023) The value of venom. Biologist, 70 (1). pp. 14-17. ISSN 0006-3347

Zharkova, O., Salamah, M. F., Babak, M. V., Rajan, E., Lim, L. H. K., Andrade, F., Gil, C. D., Oliani, S. M., Moraes, L. and Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517 (2023) Deletion of annexin A1 in mice upregulates the expression of its receptor, Fpr2/3, and reactivity to the AnxA1 mimetic peptide in platelets. International Journal of Molecular Sciences, 24 (4). 3424. ISSN 1422-0067 doi: https://doi.org/10.3390/ijms24043424

Senthilkumaran, S., Arathisenthil, S. V., Williams, J., Williams, H. F., Thirumalaikolundusubramanian, P., Patel, K. and Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517 (2022) An unnecessary Russell’s Viper bite on the tongue due to live snake worship and dangerous first aid emphasise the urgent need for stringent policies. Toxins, 14 (12). 817. ISSN 2072-6651 doi: https://doi.org/10.3390/toxins14120817

Senthilkumaran, S., Miller, S. W., Williams, H. F., Thirumalaikolundusubramanian, P., Patel, K. and Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517 (2022) Bilateral simultaneous optic neuritis following envenomations by Indian cobra and common krait. Toxins, 14 (11). 805. ISSN 2072-6651 doi: https://doi.org/10.3390/toxins14110805

Ramprasath, T., Natarajan, N., Gopas, J., Subbiah, R., Rajendran, P. and Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517, eds. (2022) Development of novel small molecules as therapeutics for inflammatory diseases and delineating their molecular mechanisms. Frontiers in Pharmacology. Frontiers. (In Press)

Senthilkumaran, S., Miller, S. W., Williams, H. F., Thirumalaikolundusubramanian, P., Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517 and Patel, K. (2022) Hirata’s disease (insulin autoimmune syndrome) following envenomation by a common krait. Toxicon, 219. 106923. ISSN 0041-0101 doi: https://doi.org/10.1016/j.toxicon.2022.09.009

Senthilkumaran, S., Miller, S. W., Williams, H. F., Savania, R., Thirumalaikolundusubramanian, P., Patel, K. and Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517 (2022) Development of Wunderlich Syndrome following a Russell’s viper bite. Toxicon, 215. pp. 11-16. ISSN 0041-0101 doi: https://doi.org/10.1016/j.toxicon.2022.06.004

Alqallaf, A., Engelbeen, S., Palo, A., Cutrupi, F., Tanganyika-de Winter, C., Plomp, J., Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517, Aartsma-Rus, A., Patel, K. and Putten, M. v. (2022) The therapeutic potential of soluble activin type IIB receptor treatment in a limb girdle muscular dystrophy type 2D mouse model. Neuromuscular Disorders, 32 (5). pp. 419-435. ISSN 0960-8966 doi: https://doi.org/10.1016/j.nmd.2022.03.002

Senthilkumaran, S., Miller, S. W., Williams, H. F., Vaiyapuri, R., Savania, R., Elangovan, N., Thirumalaikolundusubramanian, P., Patel, K. and Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517 (2022) Ultrasound-guided compression method effectively counteracts Russell’s viper bite-induced pseudoaneurysm. Toxins, 14 (4). 260. ISSN 2072-6651 doi: https://doi.org/10.3390/toxins14040260

Arathisenthil, S. V., Senthilkumaran, S., Vijayakumar, P., Savania, R., Williams, H. F., Elangovan, N., Bicknell, A. B., Patel, K., Trim, S. A., Thirumalaikolundusubramanian, P. and Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517 (2022) Rapid development of a salivary calculus in submandibular gland and its potential causes in a young victim following Russell’s viper bite. Toxicon, 206. pp. 85-89. ISSN 0041-0101 doi: https://doi.org/10.1016/j.toxicon.2021.12.018

Albadawi, D. A. I., Ravishankar, D., Vallance, T. M., Patel, K., Osborn, H. M. I. ORCID: https://orcid.org/0000-0002-0683-0457 and Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517 (2022) Impacts of commonly used edible plants on the modulation of platelet function. International Journal of Molecular Sciences, 23 (2). 605. ISSN 1422-0067 doi: https://doi.org/10.3390/ijms23020605

Hernández-Altamirano, J. A., Salazar-Valenzuela, D., Medina-Villamizar, E. J., Quirola, D. R., Patel, K., Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517, Lomonte, B. and Almeida, J. R. (2022) First insights into the venom composition of two Ecuadorian coral snakes. International Journal of Molecular Sciences, 23 (23). 14686. ISSN 1422-0067 doi: https://doi.org/10.3390/ijms232314686

Senthilkumaran, S., Vijayakumar, P., Savania, R., Vaiyapuri, R., Elangovan, N., Patel, K., Trim, S. A., Thirumalaikolundusubramanian, P. and Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517 (2021) Splenic rupture and subsequent splenectomy in a young healthy victim following Russell’s viper bite. Toxicon, 204. pp. 9-13. ISSN 0041-0101 doi: https://doi.org/10.1016/j.toxicon.2021.10.010

Senthilkumaran, S., Patel, K., Salim, A., Vijayakumar, P., Williams, H. F., Vaiyapuri, R., Savania, R., Elangovan, N., Thirumalaikolundusubramanian, P., Baksh, M. F. ORCID: https://orcid.org/0000-0003-3107-8815 and Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517 (2021) Neutrophil gelatinase-associated lipocalin acts as a robust early diagnostic marker for renal replacement therapy in patients with Russell’s viper bite-induced acute kidney injuries. Toxins, 13 (11). 797. ISSN 2072-6651 doi: https://doi.org/10.3390/toxins13110797

Alatawi, K., Ravishankar, D., Patra, P., Bye, A. ORCID: https://orcid.org/0000-0002-2061-2253, Stainer, A., Patel, K., Widera, D. ORCID: https://orcid.org/0000-0003-1686-130X and Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517 (2021) 1,8-cineole affects agonists-induced platelet activation, thrombus formation and haemostasis. Cells, 10 (10). 2616. ISSN 2073-4409 doi: https://doi.org/10.3390/cells10102616

Suarez-Berumen, K., Collins-Hooper, H., Gormova, A., Meech, R., Sacco, A., Dash, P., Mitchell, R., Shestopalov, V., Woolley, T., Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517, Patel, K. and Makarenkova, H. (2021) Pannexin 1 regulates skeletal muscle regeneration by promoting bleb-based myoblast migration and fusion through a novel lipid based signaling mechanism. Frontiers in Cell and Developmental Biology, 9. 736813. ISSN 2296-634X doi: https://doi.org/10.3389/fcell.2021.736813

Senthilkumaran, S., Williams, H. F., Patel, K., Trim, S. A., Thirumalaikolundusubramanian, P. and Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517 (2021) Priapism following a juvenile Russell’s viper bite: an unusual case report. PLoS Neglected Tropical Diseases, 15 (3). ISSN 1935-2735 doi: https://doi.org/10.1371/journal.pntd.0009242

Vaughan, D., Mitchell, R., Kretz, O., Chambers, D., Lalowski, M., Amthor, H., Ritvos, O., Pasternack, A., Matsakas, A., Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517, Huber, T. B., Denecke, B., Mukherjee, A., Widera, D. ORCID: https://orcid.org/0000-0003-1686-130X and Patel, K. (2021) A muscle growth promoting treatment based on the attenuation of activin/myostatin signalling in young mice results in long-term testicular abnormalities. Disease Models & Mechanisms, 14 (2). ISSN 1754-8411 doi: https://doi.org/10.1242/dmm.047555

Sahli, K. A., Flora, G. D., Sasikumar, P., Maghrabi, A. H., Holbrook, L., AlOuda, S. K., Elgheznawy, A., Sage, T., Stainer, A. R., Adiyaman, R., AboHassan, M., Crescente, M., Kriek, N., Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517, Bye, A. P. ORCID: https://orcid.org/0000-0002-2061-2253, Unsworth, A. J., Jones, C. I. ORCID: https://orcid.org/0000-0001-7537-1509, McGuffin, L. J. ORCID: https://orcid.org/0000-0003-4501-4767 and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 (2021) Structural, functional and mechanistic insights uncover the fundamental role of orphan connexin-62 in platelets. Blood, 137 (6). pp. 830-843. ISSN 0006-4971 doi: https://doi.org/10.1182/blood.2019004575

Vallance, T., Sheard, J., Meng, Y., Torre, E., Patel, K., Widera, D. ORCID: https://orcid.org/0000-0003-1686-130X and Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517 (2021) Development and characterisation of a novel, megakaryocyte NF-κB reporter cell line for investigating inflammatory responses. Journal of Thrombosis and Haemostasis, 19 (1). pp. 107-120. ISSN 1538-7933 doi: https://doi.org/10.1111/jth.15118

Majeed, K. R., Al-Fahad, D., Jalood, H. H., Hantosh, H. A., Ali, M. K., Sakthivel, S., Williams, H. F., Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352, Patel, K., Baksh, M. F. ORCID: https://orcid.org/0000-0003-3107-8815 and Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517 (2021) RhD blood type significantly influences susceptibility to contract COVID-19 among a study population in Iraq. F1000Research. ISSN 2046-1402 doi: https://doi.org/10.12688/f1000research.27777.1

Samuel, S. P., Chinnaraju, S., Williams, H., Pichamuthu, E., Subharao, M., Vaiyapuri, M., Arumugam, S., Vaiyapuri, R., Baksh, F. ORCID: https://orcid.org/0000-0003-3107-8815, Patel, K., Trim, S., Duncombe, T. ORCID: https://orcid.org/0000-0003-4746-4470 and Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517 (2020) Venomous snakebites: rapid action saves lives - a multifaceted community education programme increases awareness about snakes and snakebites among the rural population of Tamil Nadu, India. PLoS Neglected Tropical Diseases, 14 (12). e0008911. ISSN 1935-2735 doi: https://doi.org/10.1371/journal.pntd.0008911

Trim, S. A., Trim, C. M., Williams, H. F. and Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517 (2020) The failures of ethnobotany and phytomedicine in delivering novel treatments for snakebite envenomation. Toxins, 12 (12). 774. ISSN 2072-6651 doi: https://doi.org/10.3390/toxins12120774

Miller, S. W., Osterhoudt, K. C., Korenoski, A. S., Patel, K. and Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517 (2020) Exotic snakebites reported to Pennsylvania poison control centers: lessons learned on the demographics, clinical effects, and treatment of these cases. Toxins, 12 (12). 755. ISSN 2072-6651 doi: https://doi.org/10.3390/toxins12120755

Salamah, M., Vallance, T., Kodji, X., Ravishankar, D., Williams, H., Brain, S. and Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517 (2020) The antimicrobial cathelicidin CRAMP augments platelet activation during psoriasis in mice. Biomolecules, 10 (9). 1267. ISSN 2218-273X doi: https://doi.org/10.3390/biom10091267

Vaughan, D., Kretz, O., Alqallaf, A., Mitchell, R., Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517, Matsakas, A., Pasternack, A., Collins-Hooper, H., Ritvos, O., Ballesteros, R., Huber, T. B., Amthor, H., Mukherjee, A. and Patel, K. (2020) Diminution in sperm quantity and quality in mouse models of Duchenne Muscular Dystrophy induced by a myostatin-based muscle growth-promoting intervention. European Journal of Translational Myology, 30 (2). pp. 276-285. ISSN 2037-7452 doi: https://doi.org/10.4081/ejtm.2019.8904

Knudsen, C., Casewell, N., Lomonte, B., Gutiérrez, J. M., Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517 and Laustsen, A. (2020) Novel snakebite therapeutics must be tested in appropriate rescue models to robustly assess their preclinical efficacy. Toxins, 12 (9). 528. ISSN 2072-6651 doi: https://doi.org/10.3390/toxins12090528

Layfield, H. J., Williams, H. F., Ravishankar, D., Mehmi, A., Sonavane, M., Salim, A., Vaiyapuri, R., Lakshminarayanan, K., Vallance, T. M., Bicknell, A. B., Trim, S. A., Patel, K. and Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517 (2020) Repurposing cancer drugs, batimastat and marimastat, to inhibit the activity of a group I metalloprotease from the venom of the Western Diamondback rattlesnake, Crotalus atrox. Toxins, 12 (5). 309. ISSN 2072-6651 doi: https://doi.org/10.3390/toxins12050309

Vallance, T. M., Ravishankar, D., Albadawi, D. A. I., Osborn, H. M. I. ORCID: https://orcid.org/0000-0002-0683-0457 and Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517 (2019) Synthetic flavonoids as novel modulators of platelet function and thrombosis. International Journal of Molecular Sciences, 20 (12). e3106. ISSN 1422-0067 doi: https://doi.org/10.3390/ijms20123106

Williams, H., Mellows, B., Mitchell, R., Sfyri, P., Layfield, H., Salamah, M., Vaiyapuri, R., Collins-Hooper, H., Bicknell, A., Matsakas, A., Patel, K. and Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517 (2019) Mechanisms underpinning the permanent muscle damage induced by snake venom metalloprotease. PLoS Neglected Tropical Diseases, 13 (1). e0007041. ISSN 1935-2735 doi: https://doi.org/10.1371/journal.pntd.0007041

Patel, K., Simbi, B., Ritvos, O., Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517 and Dhoot, G. K. (2019) Dysregulated cell signalling and reduced satellite cell potential in ageing muscle. Experimental Cell Research, 385 (2). 111685. ISSN 0014-4827 doi: https://doi.org/10.1016/j.yexcr.2019.111685

Vallance, T., Ravishankar, D., Albadawi, D., Layfield, H., Sheard, J., Vaiyapuri, R., Dash, P., Patel, K., Widera, D. ORCID: https://orcid.org/0000-0003-1686-130X and Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517 (2019) Effect of ultrapure lipopolysaccharides derived from diverse bacterial species on the modulation of platelet activation. Scientific Reports, 9. 18258. ISSN 2045-2322 doi: https://doi.org/10.1038/s41598-019-54617-w

Ravishankar, D., Albadawi, D., Chaggar, V., Patra, P., Williams, H., Salamah, M., Vaiyapuri, R., Dash, P., Patel, K., Watson, K. ORCID: https://orcid.org/0000-0002-9987-8539 and Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517 (2019) Isorhapontigenin, a resveratrol analogue selectively inhibits ADP-stimulated platelet activation. European Journal of Pharmacology, 862. 172627. ISSN 0014-2999 doi: https://doi.org/10.1016/j.ejphar.2019.172627

Omairi, S., Hua, K.-L., Collins-Hooper, H., Scott, C., Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517, Torelli, S., Montanero, F., Matsakas, A. and Patel, K. (2019) Regulation of the dystrophin-associated glycoprotein complex composition by the metabolic properties of muscle fibres. Scientific Reports, 9. 2770. ISSN 2045-2322 doi: https://doi.org/10.1038/s41598-019-39532-4

Salamah, M. F., Ravishankar, D., Vaiyapuri, R., Moraes, L. A., Patel, K., Perretti, M., Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 and Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517 (2019) The formyl peptide fMLF primes platelet activation and augments thrombus formation. Journal of Thrombosis and Haemostasis, 17 (7). pp. 1120-1133. ISSN 1538-7836 doi: https://doi.org/10.1111/jth.14466

Williams, H. F., Layfield, H. J., Vallance, T., Patel, K., Bicknell, A. B., Trim, S. A. and Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517 (2019) The urgent need to develop novel strategies for the diagnosis and treatment of snakebites. Toxins, 11 (6). 363. ISSN 2072-6651 doi: https://doi.org/10.3390/toxins11060363

Ravishankar, D., Salamah, M., Akimbaev, A., Williams, H. F., Albadawi, D. A. I., Vaiyapuri, R., Greco, F., Osborn, H. M. I. ORCID: https://orcid.org/0000-0002-0683-0457 and Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517 (2018) Impact of specific functional groups in flavonoids on the modulation of platelet activation. Scientific Reports, 8. 9528. ISSN 2045-2322 doi: https://doi.org/10.1038/s41598-018-27809-z

Paolini, A., Omairi, S., Mitchell, R., Vaughan, D., Matsakas, A., Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517, Ricketts, T., Rubinsztein, D. C. and Patel, K. (2018) Attenuation of autophagy impacts on muscle fibre development, starvation induced stress and fibre regeneration following acute injury. Scientific Reports, 8. 9062. ISSN 2045-2322 doi: https://doi.org/10.1038/s41598-018-27429-7

Williams, H. F., Hayter, P., Ravishankar, D., Baines, A., Layfield, H. J., Croucher, L., Wark, C., Bicknell, A. B., Trim, S. and Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517 (2018) Impact of Naja nigricollis venom on the production of methaemoglobin. Toxins, 10 (12). 539. ISSN 2072-6651 doi: https://doi.org/10.3390/toxins10120539

Salamah, M. F., Ravishankar, D., Kodji, X., Moraes, L. A., Williams, H. F., Vallance, T. M., Albadawi, D. A., Vaiyapuri, R., Watson, K. ORCID: https://orcid.org/0000-0002-9987-8539, Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352, Brain, S. D., Perretti, M. and Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517 (2018) The endogenous antimicrobial cathelicidin LL37 induces platelet activation and augments thrombus formation. Blood Advances, 2 (21). pp. 2973-2985. ISSN 2473-9529 doi: https://doi.org/10.1182/bloodadvances.2018021758

Vallance, T., Zeuner, M.-T., Williams, H., Widera, D. ORCID: https://orcid.org/0000-0003-1686-130X and Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517 (2017) Toll-like receptor 4 signalling and its impact on platelet function, thrombosis, and haemostasis. Mediators of inflammation, 2017. 9605894. ISSN 0962-9351 doi: https://doi.org/10.1155/2017/9605894

Williams, H. F., Vaiyapuri, R., Gajjeraman, P., Hutchinson, G., Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352, Bicknell, A. B. and Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517 (2017) Challenges in diagnosing and treating snakebites in a rural population of Tamil Nadu, India: the views of clinicians. Toxicon, 130. pp. 44-46. ISSN 0041-0101 doi: https://doi.org/10.1016/j.toxicon.2017.02.025

Zeuner, M.-T., Vallance, T., Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517, Cottrell, G. S. ORCID: https://orcid.org/0000-0001-9098-7627 and Widera, D. ORCID: https://orcid.org/0000-0003-1686-130X (2017) Development and characterisation of a novel NF-κB reporter cell line for investigation of neuroinflammation. Mediators of inflammation, 2017. 6209865. ISSN 0962-9351 doi: https://doi.org/10.1155/2017/6209865

Ravishankar, D., Salamah, M., Attina, A., Pothi, R., Vallance, T. M., Javed, M., Williams, H. F., Alzahrani, E. M. S., Kabova, E., Vaiyapuri, R., Shankland, K. ORCID: https://orcid.org/0000-0001-6566-0155, Gibbins, J. ORCID: https://orcid.org/0000-0002-0372-5352, Strohfeldt, K., Greco, F., Osborn, H. M. I. ORCID: https://orcid.org/0000-0002-0683-0457 and Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517 (2017) Ruthenium-conjugated chrysin analogues modulate platelet activity, thrombus formation and haemostasis with enhanced efficacy. Scientific Reports, 7. 5738. ISSN 2045-2322 doi: https://doi.org/10.1038/s41598-017-05936-3

Moraes, L. A., Unsworth, A. J., Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517, Ali, M. S., Sasikumar, P., Sage, T., Flora, G. D., Bye, A. P. ORCID: https://orcid.org/0000-0002-2061-2253, Kriek, N., Dorchies, E., Molendi-Coste, O., Dombrowicz, D., Staels, B., Bishop-Bailey, D. and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 (2016) Farnesoid X Receptor and its ligands inhibit the function of platelets. Arteriosclerosis Thrombosis and Vascular Biology, 36 (12). pp. 2324-2333. ISSN 1524-4636 doi: https://doi.org/10.1161/ATVBAHA.116.308093

Crescente, M., Pluthero, F. G., Li, L., Lo, R. W., Walsh, T. G., Schenk, M. P., Holbrook, L. M., Loureiro, S. ORCID: https://orcid.org/0009-0000-8886-6893, Ali, M. S., Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517, Falet, H., Jones, I. M. ORCID: https://orcid.org/0000-0002-7738-2516, Poole, A. W., Kahr, W. H. A. and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 (2016) Intracellular trafficking, localization, and mobilization of platelet-borne thiol isomerases. Arteriosclerosis Thrombosis and Vascular Biology, 36 (6). pp. 1164-1173. ISSN 1079-5642 doi: https://doi.org/10.1161/ATVBAHA.116.307461

Mazet, F., Dunster, J. L., Jones, C. I. ORCID: https://orcid.org/0000-0001-7537-1509, Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517, Tindall, M. J., Fry, M. J. and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 (2015) A high-density immunoblotting methodology for quantification of total protein levels and phosphorylation modifications. Scientific Reports, 5. 16995. ISSN 2045-2322 doi: https://doi.org/10.1038/srep16995

Bye, A. P. ORCID: https://orcid.org/0000-0002-2061-2253, Unsworth, A. J., Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517, Stainer, A. R., Fry, M. J. and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 (2015) Ibrutinib inhibits platelet integrin αIIbβ3 outside-in signaling and thrombus stability but not adhesion to collagen. Arteriosclerosis Thrombosis and Vascular Biology, 35 (11). pp. 2326-2335. ISSN 1524-4636 doi: https://doi.org/10.1161/ATVBAHA.115.306130

Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517, Roweth, H., Ali, M., Unsworth, A., Stainer, A., Flora, G., Crescente, M., Jones, C. ORCID: https://orcid.org/0000-0001-7537-1509, Moraes, L. and Gibbins, J. ORCID: https://orcid.org/0000-0002-0372-5352 (2015) Pharmacological actions of nobiletin in the modulation of platelet function. British Journal of Pharmacology, 172 (16). pp. 4133-4145. ISSN 0007-1188 doi: https://doi.org/10.1111/bph.13191

Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517, Sunagar, K., Gibbins, J. ORCID: https://orcid.org/0000-0002-0372-5352, Jackson, T. N. W., Reeks, T. and Fry, B. G. (2015) Kallikrein enzymes. In: Fry, B. (ed.) Venomous reptiles and their toxins: evolution, pathophysiology and biodiscovery. Oxford University Press, New York, pp. 267-280. ISBN 9780199309399

Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517, Flora, G. D. and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 (2015) Gap junctions and connexin hemichannels in the regulation of haemostasis and thrombosis. Biochemical Society Transactions, 43 (3). pp. 489-494. ISSN 1470-8752 doi: https://doi.org/10.1042/BST20150055

Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517, Sage, T., Rana, R. H., Schenk, M. P., Ali, M. S., Unsworth, A. J., Jones, C. I. ORCID: https://orcid.org/0000-0001-7537-1509, Stainer, A. R., Kriek, N. K., Moraes, L. A. and Gibbins, J. ORCID: https://orcid.org/0000-0002-0372-5352 (2015) EphB2 regulates contact-dependent and independent signalling to control platelet function. Blood, 125 (4). pp. 720-730. ISSN 0006-4971 doi: https://doi.org/10.1182/blood-2014-06-585083

Jones, C. I. ORCID: https://orcid.org/0000-0001-7537-1509, Sage, T., Moraes, L. A., Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517, Hussain, U., Tucker, K. L., Barrett, N. E. ORCID: https://orcid.org/0000-0001-9123-1100 and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 (2014) Platelet endothelial cell adhesion molecule-1 inhibits platelet response to thrombin and von Willebrand factor by regulating the internalization of glycoprotein Ib via AKT/glycogen synthase kinase-3/dynamin and integrin αIIbβ3. Arteriosclerosis Thrombosis and Vascular Biology, 34 (9). pp. 1968-1976. ISSN 1079-5642 doi: https://doi.org/10.1161/ATVBAHA.114.304097

Lewin, M. R., Samuel, S. P., Wexler, D. S., Bickler, P., Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517 and Mensh, B. D. (2014) Early treatment with intranasal neostigmine reduces mortality in a mouse model of Naja naja (Indian Cobra) envenomation. Journal of Tropical Medicine, 2014. 131835. ISSN 1687-9686 doi: https://doi.org/10.1155/2014/131835

Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517, Ali, M. S., Moraes, L. A., Sage, T., Lewis, K. R., Jones, C. I. ORCID: https://orcid.org/0000-0001-7537-1509 and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 (2013) Tangeretin regulates platelet function through inhibition of phosphoinositide 3-Kinase and cyclic nucleotide signaling. Arteriosclerosis Thrombosis and Vascular Biology, 33 (12). pp. 2740-2749. ISSN 1079-5642 doi: https://doi.org/10.1161/ATVBAHA.113.301988

Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517, Vaiyapuri, R., Ashokan, R., Ramasamy, K., Nattamaisundar, K., Jeyaraj, A., Chandran, V., Gajjeraman, P., Baksh, M. F. ORCID: https://orcid.org/0000-0003-3107-8815, Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 and Hutchinson, E. G. (2013) Snakebite and its socio-economic impact on the rural population of Tamil Nadu, India. PLoS ONE, 8 (11). e80090. ISSN 1932-6203 doi: https://doi.org/10.1371/journal.pone.0080090

Moraes, L. A., Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517, Sasikumar, P., Ali, M. S., Kriek, N. K., Sage, T. and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 (2013) Antithrombotic actions of statins involve PECAM-1 signalling. Blood, 122 (18). pp. 3188-3196. ISSN 0006-4971 doi: https://doi.org/10.1182/blood-2013-04-491845

Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517, Moraes, L. A., Sage, T., Ali, M. S., Lewis, K. R., Mayhaut-Smith, M. P., Oviedo-Orta, E., Simon, A. M. and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 (2013) Connexin40 regulates platelet function. Nature Communications, 4. pp. 2564-2572. ISSN 2041-1723 doi: https://doi.org/10.1038/ncomms3564

Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517 (2013) Sequence and functional analysis of viper venom proteolytic enzymes. Lambert Academic Publishing, Saarbrucken. ISBN 9783659399183

Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517, Thiyagarajan, N., Hutchinson, E. G. and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 (2012) Sequence and phylogenetic analysis of viper venom serine proteases. Bioinformation, 8 (16). pp. 763-772. ISSN 0973-2063

Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517, Hutchinson, E. G., Ali, M. S., Dannoura, A., Stanley, R. G., Harrison, R. A., Bicknell, A. B. and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 (2012) Rhinocetin, a venom-derived integrin-specific antagonist inhibits collagen-induced platelet and endothelial cell functions. The Journal of Biological Chemistry, 287 (31). pp. 26235-26244. ISSN 1083-351X doi: https://doi.org/10.1074/jbc.M112.381483

Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517, Jones, C. I. ORCID: https://orcid.org/0000-0001-7537-1509, Sasikumar, P., Moraes, L. A., Munger, S. J., Wright, J. R., Ali, M. S., Sage, T., Kaiser, W. J., Tucker, K. L., Stain, C. J., Bye, A. P., Jones, S., Oviedo-Orta, E., Simon, A. M., Mahaut-Smith, M. P. and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 (2012) Gap junctions and connexin hemichannels underpin hemostasis and thrombosis. Circulation, 125 (20). pp. 2479-2491. ISSN 0009-7322 doi: https://doi.org/10.1161/CIRCULATIONAHA.112.101246

Elashry, M. I., Collins-Hooper, H., Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517 and Patel, K. (2012) Characterisation of connective tissue from the hypertrophic skeletal muscle of myostatin null mice. Journal of Anatomy, 220 (6). pp. 603-611. ISSN 0021-8782 doi: https://doi.org/10.1111/j.1469-7580.2012.01503.x

Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517, Wagstaff, S. C., Harrison, R. A., Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 and Hutchinson, G. (2011) Evolutionary analysis of novel serine proteases in the venom gland transcriptome of Bitis gabonica rhinoceros. PLoS ONE, 6 (6). e21532. ISSN 1932-6203 doi: https://doi.org/10.1371/journal.pone.0021532

Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517, Wagstaff, S. C., Watson, K. A. ORCID: https://orcid.org/0000-0002-9987-8539, Harrison, R. A., Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 and Hutchinson, E. G. (2010) Purification and functional characterisation of rhiminopeptidase A, a novel aminopeptidase from the venom of Bitis gabonica rhinoceros. PLoS Neglected Tropical Diseases, 4 (8). e796. ISSN 1935-2735 doi: https://doi.org/10.1371/journal.pntd.0000796

Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517, Harrison, R. A., Bicknell, A., Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 and Hutchinson, E. G. (2010) Purification and functional characterisation of Rhinocerase, a novel serine protease from the venom of Bitis gabonica rhinoceros. PLoS ONE, 5 (3). e9687. ISSN 1932-6203 doi: https://doi.org/10.1371/journal.pone.0009687

Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517 (2008) Sequence, Structure and Functional Studies of Viper Venom Proteolytic Enzymes. PhD thesis, University of Reading.

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