Article

Cobb, A. J. A., Dell’Isola, A., Abdulsattar, B. O., McLachlan, M. M. W., Neuman, B. W., Müller, C., Shankland, K. ORCID: https://orcid.org/0000-0001-6566-0155, Al-Mulla, H. M. N., Binks, A. W. D. and Elvidge, W. (2018) Synthesis and antiviral activity of novel spirocyclic nucleosides. New Journal of Chemistry, 42 (22). pp. 18363-18380. ISSN 1144-0546 doi: https://doi.org/10.1039/c8nj02777c

Doyle, N., Neuman, B. W., Simpson, J., Hawes, P. C., Mantell, J., Verkade, P., Alrashedi, H. and Maier, H. J. (2018) Infectious bronchitis virus nonstructural protein 4 alone induces membrane pairing. Viruses, 10 (9). 477. ISSN 1999-4915 doi: https://doi.org/10.3390/v10090477

Neuman, B. W. (2016) Bioinformatics and functional analyses of coronavirus nonstructural proteins involved in the formation of replicative organelles. Antiviral Research, 135. pp. 97-107. ISSN 0166-3542 doi: https://doi.org/10.1016/j.antiviral.2016.10.005

Zeng, C., Wu, A., Wang, Y., Xu, S., Tang, Y., Jin, X., Wang, S., Qin, L., Sun, Y., Fan, C., Snijder, E. J., Neuman, B. W., Chen, Y., Ahola, T. and Guo, D. (2016) Identification and characterization of a ribose 2′-O-methyltransferase encoded by the ronivirus branch of Nidovirales. Journal of Virology, 90 (15). pp. 6675-6685. ISSN 1098-5514 doi: https://doi.org/10.1128/JVI.00658-16

Maier, H. J., Neuman, B. W., Bickerton, E., Keep, S. M., Alrashedi, H., Hall, R. and Britton, P. (2016) Extensive coronavirus-induced membrane rearrangements are not a determinant of pathogenicity. Scientific Reports, 6. 27126. ISSN 2045-2322 doi: https://doi.org/10.1038/srep27126

Dent, S., Xia, D., Wastling, J., Neuman, B., Britton, P. and Maier, H. (2015) The proteome of the infectious bronchitis virus Beau-R Virion. Journal of General Virology, 96 (12). pp. 3499-3506. ISSN 0022-1317 doi: https://doi.org/10.1099/jgv.0.000304

Iftikhar, Y., Jackson, R. and Neuman, B. W. (2015) Detection of tobacco mosaic tobamovirus in cigarettes through RT-PCR. Pakistan Journal of Agricultural Sciences, 52 (3). pp. 667-670. ISSN 0552-9034

V'kovski, P., Al-Mulla, H., Thiel, V. and Neuman, B. W. (2015) New insights on the role of paired membrane structures in coronavirus replication. Virus Research, 202. pp. 33-40. ISSN 0168-1702 doi: https://doi.org/10.1016/j.virusres.2014.12.021

Dell'Isola, A., McLachlan, M. M. W., Neuman, B. W., Al-Mullah, H. M. N., Binks, A. W. D., Elvidge, W., Shankland, K. ORCID: https://orcid.org/0000-0001-6566-0155 and Cobb, A. J. A. (2014) Synthesis and antiviral properties of spirocyclic [1,2,3]-triazolooxazine nucleosides. Chemistry- A European Journal, 20 (37). pp. 11685-11689. ISSN 0947-6539 doi: https://doi.org/10.1002/chem.201403560

Neuman, B. W., Angelini, M. M. and Buchmeier, M. J. (2014) Does form meet function in the coronavirus replicative organelle? Trends in Microbiology, 22 (11). pp. 642-647. ISSN 0966-842X doi: https://doi.org/10.1016/j.tim.2014.06.003

Dent, S. and Neuman, B. (2014) Purification of coronavirus virions for Cryo-EM and proteomic analysis. Methods in Molecular Biology, 1282. pp. 99-108. ISSN 1064-3745 doi: https://doi.org/10.1007/978-1-4939-2438-7_10

Al-Mulla, H. M. N., Turrell, L., Smith, N. M., Payne, L., Baliji, S., Züst, R., Thiel, V., Baker, S. C., Siddell, S. G. and Neuman, B. W. (2014) Competitive fitness in coronaviruses is not correlated with size or number of double-membrane vesicles under reduced-temperature growth conditions. mBio, 5 (2). e01107-13. ISSN 2150-7511 doi: https://doi.org/10.1128/mBio.01107-13

Angelini, M. M., Neuman, B. W. and Buchmeier, M. J. (2014) Untangling membrane rearrangement in the Nidovirales. DNA and Cell Biology, 33 (3). pp. 122-127. ISSN 1044-5498 doi: https://doi.org/10.1089/dna.2013.2304

Neuman, B. W. (2013) How the double spherules of infectious bronchitis virus impact our understanding of RNA virus replicative organelles. mBio, 4 (6). pp. 1-3. ISSN 2150-7511 doi: https://doi.org/10.1128/mBio.00987-13

Neuman, B. W., Chamberlain, P., Bowden, F. and Joseph, J. (2013) Atlas of coronavirus replicase structure. Virus research, 194. pp. 49-66. ISSN 1872-7492 doi: https://doi.org/10.1016/j.virusres.2013.12.004

Schley, D., Whittaker, R. J. and Neuman, B. W. (2013) Arenavirus budding resulting from viral-protein-associated cell membrane curvature. Journal of the Royal Society Interface, 10 (86). 20130403. ISSN 1742-5662 doi: https://doi.org/10.1098/rsif.2013.0403

Neuman, B. W., Kiss, G., Al-Mulla, H. M. N., Dokland, T., Buchmeier, M. J., Weikl, T. and Schley, D. (2013) Direct observation of membrane insertion by enveloped virus matrix proteins by phosphate displacement. PLoS ONE, 8 (2). e57916. ISSN 1932-6203

Angelini, M. M., Akhlaghpour, M., Neuman, B. W. and Buchmeier, M. J. (2013) Severe acute respiratory syndrome coronavirus nonstructural proteins 3, 4, and 6 induce double-membrane vesicles. mBio, 4 (4). e00524-13. ISSN 2150-7511 doi: https://doi.org/10.1128/mBio.00524-13

Neuman, B. W., Bederka, L. H., Stein, D. A., Ting, J. P. C., Moulton, H. M. and Buchmeier, M. J. (2011) Development of peptide-conjugated morpholino oligomers as pan-arenavirus inhibitors. Antimicrobial Agents and Chemotherapy, 55 (10). pp. 4631-4638. ISSN 1098-6596 doi: https://doi.org/10.1128/AAC.00650-11

Neuman, B. W., Kiss, G., Kunding, A. H., Bhella, D., Baksh, M. F. ORCID: https://orcid.org/0000-0003-3107-8815, Connelly, S., Droese, B., Klaus, J. P., Makino, S., Sawicki, S. G., Siddell, S. G., Stamou, D. G., Wilson, I. A., Kuhn, P. and Buchmeier, M. J. (2011) A structural analysis of M protein in coronavirus assembly and morphology. Journal of Structural Biology, 174 (1). pp. 11-22. ISSN 1047-8477 doi: https://doi.org/10.1016/j.jsb.2010.11.021

Zust, R., Cervantes-Barragan, L., Habjan, M., Maier, R., Neuman, B. W., Ziebuhr, J., Szretter, K. J., Baker, S. C., Barchet, W., Diamond, M. S., Siddell, S. G., Ludewig, B. and Thiel, V. (2011) Ribose 2′-O-methylation provides a molecular signature for the distinction of self and non-self mRNA dependent on the RNA sensor Mda5. Nature Immunology, 12. pp. 137-143. ISSN 1529-2916 doi: https://doi.org/10.1038/ni.1979

Johnson, M. A., Chatterjee, A., Neuman, B. W. and Wuthrich, K. (2010) SARS coronavirus unique domain: three-domain molecular architecture in solution and RNA binding. Journal of Molecular Biology, 400 (4). pp. 724-742. ISSN 0022-2836 doi: https://doi.org/10.1016/j.jmb.2010.05.027

Serrano, P., Johnson, M. A., Chatterjee, A., Neuman, B. W., Joseph, J. S., Buchmeier, M. J., Kuhn, P. and Wuthrich, K. (2009) Nuclear magnetic resonance structure of the nucleic acid-binding domain of severe acute respiratory syndrome coronavirus nonstructural protein 3. Journal of Virology, 83 (24). pp. 12998-13008. ISSN 0022-538X doi: https://doi.org/10.1128/jvi.01253-09

Chatterjee, A., Johnson, M. A., Serrano, P., Pedrini, B., Joseph, J. S., Neuman, B. W., Saikatendu, K., Buchmeier, M. J., Kuhn, P. and Wüthrich, K. (2009) Nuclear magnetic resonance structure shows that the severe acute respiratory syndrome coronavirus-unique domain contains a macrodomain fold. Journal of Virology, 83 (4). pp. 1823-1836. ISSN 0022-538X doi: https://doi.org/10.1128/jvi.01781-08

Chatterjee, A., Johnson, M. A., Serrano, P., Pedrini, B., Joseph, J. J., Neuman, B. W., Saikatendu, K., Buchmeier, M. J., Kuhn, P. and Wuthrich, K. (2008) NMR structure shows that the SARS-unique domain contains a macrodomain fold. Journal of Virology, 83. pp. 12998-13008. ISSN 0022-538X doi: https://doi.org/10.1128/JVI.01781-08

Neuman, B. W., Joseph, J. S., Saikatendu, K. S., Serrano, P., Chatterjee, A., Johnson, M. A., Liao, L., Klaus, J. P., Yates, J. R., Wuethrich, K., Stevens, R. C., Buchmeier, M. J. and Kuhn, P. (2008) Proteornics analysis unravels the functional repertoire of coronavirus nonstructural protein 3. Journal of Virology, 82 (11). pp. 5279-5294. ISSN 0022-538X doi: https://doi.org/10.1128/jvi.02631-07

Neuman, B. W., Adair, B. D., Yeager, M. and Buchmeier, M. J. (2008) Purification and electron cryomicroscopy of coronavirus particles. Methods in Molecular Biology, 454. pp. 129-36. ISSN 1064-3745 doi: https://doi.org/10.1007/978-1-59745-181-9_12

Burrer, R., Neuman, B. W., Ting, J. P., Stein, D. A., Moulton, H. M., Iversen, P. L., Kuhn, P. and Buchmeier, M. J. (2007) Antiviral effects of antisense morpholino oligomers in murine coronavirus infection models. The Journal of Virology, 81 (11). pp. 5637-48. ISSN 0022-538X doi: https://doi.org/10.1128/JVI.02360-06

Moulton, H. M., Fletcher, S., Neuman, B. W., McClorey, G., Stein, D. A., Abes, S., Wilton, S. D., Buchmeier, M. J., Lebleu, B. and Iversen, P. L. (2007) Cell-penetrating peptide-morpholino conjugates alter pre-mRNA splicing of DMD (Duchenne muscular dystrophy) and inhibit murine coronavirus replication in vivo. Biochemical Society Transactions, 35 (4). pp. 826-8. ISSN 0300-5127

Joseph, J. S., Saikatendu, K. S., Subramanian, V., Neuman, B. W., Buchmeier, M. J., Stevens, R. C. and Kuhn, P. (2007) Crystal structure of a monomeric form of SARS-CoV endonuclease nsp15 suggests a role for hexamerization as an allosteric switch. Journal of Virology, 81 (12). pp. 6700-8. ISSN 0022-538X doi: https://doi.org/10.1128/JVI.02817-06

Saunders, A. A., Ting, J. P., Meisner, J., Neuman, B. W., Perez, M., de la Torre, J. C. and Buchmeier, M. J. (2007) Mapping the landscape of the lymphocytic choriomeningitis virus stable signal peptide reveals novel functional domains. Journal of Virology, 81 (11). pp. 5649-57. ISSN 0022-538X doi: https://doi.org/10.1128/JVI.02759-06

Serrano, P., Johnson, M. A., Almeida, M. S., Horst, R., Herrmann, T., Joseph, J. S., Neuman, B. W., Subramanian, V., Saikatendu, K. S., Buchmeier, M. J., Stevens, R. C., Kuhn, P. and Wuthrich, K. (2007) Nuclear magnetic resonance structure of the N-terminal domain of nonstructural protein 3 from the severe acute respiratory syndrome coronavirus. Journal of Virology, 81 (21). pp. 12049-60. ISSN 0022-538X doi: https://doi.org/10.1128/JVI.00969-07

Saikatendu, K. S., Joseph, J. S., Subramanian, V., Neuman, B. W., Buchmeier, M. J., Stevens, R. C. and Kuhn, P. (2007) Ribonucleocapsid formation of severe acute respiratory syndrome coronavirus through molecular action of the N-terminal domain of N protein. Journal of Virology, 81 (8). pp. 3913-21. ISSN 0022-538X doi: https://doi.org/10.1128/JVI.02236-06

Book or Report Section

Neuman, B. W. and Buchmeier, M. J. (2016) Supramolecular architecture of the coronavirus particle. In: Ziebuhr, J. (ed.) Coronaviruses. Advances in Virus Research, 96 (96). Elsevier , Amsterdam, The Netherlands, pp. 1-27. ISBN 9780128047361 doi: https://doi.org/10.1016/bs.aivir.2016.08.005

Conference or Workshop Item

Stuart, A., Prescott, C., MacIntyre, S., Sethar, A., Neuman, B., McCarthy, N. D., Wimalarathna, H. and Maiden, M. C. J. (2011) The role of rodents as carriers of disease on UK farms: a preliminary investigation. In: 8th European Vertebrate Pest Management Conference, 26-30 September 2011, Berlin, Germany, pp. 198-199. (Unpublished) (Proceedings of the 8th European Vertebrate Pest Management Conference)

Patent

Sarepta Pharmaceuticals, The Scripps Research Institute (2014) Oligonucleotide compound and method for treating nidovirus infections. . (USOO8759307B2)