Items where Author is "Spencer, Professor Jeremy"
Group by: Item Type | No Grouping Number of items: 143. Article
ALbuloshi, Thurayya
Albuloshi, T., Dimala, C. A., Kuhnle, G. G. C.
Huarte, Estíbaliz Turner, Alice L., Michaelson, Louise V., Shewry, Peter R., Lovegrove, Alison and Spencer, Jeremy P. E. (2021) Increased bioavailability of phenolic acids and enhanced vascular function following intake of feruloyl esterase-processed high fibre bread: a randomized, controlled, single blind, crossover human intervention trial. Clinical Nutrition, 40 (3). pp. 788-795. ISSN 0261-5614 doi: https://doi.org/10.1016/j.clnu.2020.07.026
Vauzour, David, Rendeiro, Catarina, D'Amato, Alfonsina, Waffo-Teguo, Pierre, Richard, Tristan, Merillon, Jean Michel, Pontifex, Matthew G., Connell, Emily, Muller, Michael, Butler, Laurie T., Williams, Claire M. Flanagan, Emma, Lamport, Daniel, Brennan, Lorraine, Burnet, Philip, Calabrese, Vittorio, Cunnane, Stephen C., de Wilde, Martijn C., Dye, Louise, Farrimond, Jonathan A., Emerson Lombardo, Nancy, Hartmann, Tobias, Hartung, Thomas, Kalliomäki, Marko, Kuhnle, Gunter G., La Fata, Giorgio, Sala-Vila, Aleix, Samieri, Cécilia, Smith, A. David, Spencer, Jeremy P. E., Thuret, Sandrine, Tuohy, Kieran, Turroni, Silvia, Vanden Berghe, Wim, Verkuijl, Martin, Verzijden, Karin, Yannakoulia, Mary, Geurts, Lucie and Vauzour, David (2020) Nutrition and the ageing brain: moving towards clinical applications. Ageing Research Reviews, 62. 101079. ISSN 1568-1637 doi: https://doi.org/10.1016/j.arr.2020.101079 Alañón, M. E., Castle, S. M., Serra, G., Lévèques, A., Poquet, L., Actis-Goretta, L. and Spencer, J. P. E. (2020) Acute study of dose-dependent effects of (-)-epicatechin on vascular function in healthy male volunteers: a randomized controlled trial. Clinical Nutrition, 39 (3). pp. 746-754. ISSN 0261-5614 doi: https://doi.org/10.1016/j.clnu.2019.03.041
Bell, Lynne, Whyte, Adrian R., Lamport, Daniel J. Soycan, Gulten, Schar, Manuel, Kristek, Angelika, Boberska, Joanna, Alsharif, Sarah N. S., Corona, Giulia, Shewry, Peter R. and Spencer, Jeremy P. E. (2019) Composition and content of phenolic acids and avenanthramides in commercial oat products: are oats an important polyphenol source for consumers? Food Chemistry: X, 3. 100047. ISSN 2590-1575 doi: https://doi.org/10.1016/j.fochx.2019.100047 Dodd, Georgina F., Williams, Claire M., Butler, Laurie T. and Spencer, Jeremy P. E. (2019) Acute effects of flavonoid-rich blueberry on cognitive and vascular function in healthy older adults. Nutrition and Healthy Aging, 5 (2). pp. 119-132. ISSN 2451-9502 doi: https://doi.org/10.3233/nha-180056
Mascal, Mark, Hafezi, Nema, Wang, Deping, Hu, Yuhan, Serra, Gessica, Dallas, Mark L. Kristek, Angelika, Wiese, Maria, Heuer, Patrizia, Kosik, Ondrej, Schar, Manuel Y., Soycan, Gulten, Alsharif, Sarah, Kuhnle, Gunter G. C., Walton, Gemma and Spencer, Jeremy P. E. (2019) Oat bran, but not its isolated bioactive β-glucans or polyphenols, have a bifidogenic effect in an in vitro fermentation model of the gut microbiota. British Journal of Nutrition, 121 (5). pp. 549-559. ISSN 0007-1145 doi: https://doi.org/10.1017/S0007114518003501 Kristek, A., Schar, M. Y., Soycan, G., Alsharif, S., Kuhnle, G. G. C., Walton, G. and Spencer, J. P. E. (2018) The gut microbiota and cardiovascular health benefits: a focus on wholegrain oats. Nutrition Bulletin, 43 (4). pp. 358-373. ISSN 1471-9827 doi: https://doi.org/10.1111/nbu.12354 Baldrick, Francina R, McFadden, Kevin, Ibars, Maria, Sung, Chris, Moffatt, Tanya, Megarry, Kate, Thomas, Keith, Mitchell, Peter, Wallace, Julie M. W., Pourshahidi, L. Kirsty, Ternan, Nigel G., Corona, Giulia, Spencer, Jeremy, Yaqoob, Parveen, Hotchkiss, Sarah, Campbell, Ross, Moreno-Rojas, José Manuel, Cuevas, Francisco Julián, Pereira-Caro, Gema, Rowland, Ian and Gill, Chris I. R. (2018) Impact of a (poly)phenol-rich extract from the brown algae Ascophyllum nodosum on DNA damage and antioxidant activity in an overweight or obese population: a randomized controlled trial. American Journal of Clinical Nutrition, 108 (4). pp. 688-700. ISSN 0002-9165 doi: https://doi.org/10.1093/ajcn/nqy147 Marques, Cláudia, Fernandes, Iva, Meireles, Manuela, Faria, Ana, Spencer, Jeremy, Mateus, Nuno and Calhau, Conceição (2018) Gut microbiota modulation accounts for the neuroprotective properties of anthocyanins. Scientific Reports, 8 (1). 11341. ISSN 2045-2322 doi: https://doi.org/10.1038/s41598-018-29744-5 Vauzour, David, Corsini, Simone, Müller, Michael and Spencer, Jeremy P. E. (2018) Inhibition of PP2A by hesperetin may contribute to Akt and ERK1/2 activation status in cortical neurons. Archives of Biochemistry and Biophysics, 650. pp. 14-21. ISSN 0003-9861 doi: https://doi.org/10.1016/j.abb.2018.04.020 Amini, Anna M., Spencer, Jeremy P. E. and Yaqoob, Parveen (2018) Effects of pelargonidin-3-O-glucoside and its metabolites on lipopolysaccharide-stimulated cytokine production by THP-1 monocytes and macrophages. Cytokine, 103. pp. 29-33. ISSN 1096-0023 doi: https://doi.org/10.1016/j.cyto.2017.12.031 Miquel, Sophie, Champ, Claire, Day, Jon, Aarts, Esther, Bahr, Ben A., Bakker, Martijntje, Bánáti, Diána, Calabrese, Vittorio, Cederholm, Tommy, Cryan, John, Dye, Louise, Farrimond, Jonathan A., Korosi, Aniko, Layé, Sophie, Maudsley, Stuart, Milenkovic, Dragan, Mohajeri, M. Hasan, Sijben, John, Solomon, Alina, Spencer, Jeremy P. E., Thuret, Sandrine, Vanden Berghe, Wim, Vauzour, David, Vellas, Bruno, Wesnes, Keith, Willatts, Peter, Wittenberg, Raphael and Geurts, Lucie (2018) Poor cognitive ageing: vulnerabilities, mechanisms and the impact of nutritional interventions. Ageing research reviews, 42. pp. 40-55. ISSN 1568-1637 doi: https://doi.org/10.1016/j.arr.2017.12.004 Ottaviani, Javier I., Heiss, Christian, Spencer, Jeremy P., Kelm, Malte and Schroeter, Hagen (2018) Recommending flavanols and procyanidins for cardiovascular health: revisited. Molecular Aspects of Medicine. ISSN 0098-2997 doi: https://doi.org/10.1016/j.mam.2018.02.001 Schar, Manuel Y., Corona, Giulia, Soycan, Gulten, Dine, Clemence, Kristek, Angelika, Alsharif, Sarah N. S., Behrends, Volker, Lovegrove, Alison, Shewry, Peter R. and Spencer, Jeremy P. E. (2018) Excretion of avenanthramides, phenolic acids and their major metabolites following intake of oat bran. Molecular Nutrition and Food Research, 62 (2). 1700499. ISSN 1613-4133 doi: https://doi.org/10.1002/mnfr.201700499 Rees, Amy, Dodd, Georgina F. and Spencer, Jeremy P. E. (2018) The effects of flavonoids on cardiovascular health: a review of human intervention trials and implications for cerebrovascular function. Nutrients, 10 (12). 1852. ISSN 2072-6643 doi: https://doi.org/10.3390/nu10121852 Mills, Charlotte E., Flury, Andreas, Marmet, Cynthia, Poquet, Laura, Rimaldi, Stefano F., Sartori, Claudio, Rexhag, Emrush, Brenner, Roman, Allman, Yves, Zimmerman, Diane, Gibson, Glenn R., Mottram, Don S., Oruna-Concha, Maria-Jose, Actis-Goretta, Lucas and Spencer, Jeremy P. E. (2017) Mediation of coffee-induced improvements in human vascular function by chlorogenic acids and its metabolites: two randomized, controlled, crossover intervention trials. Clinical Nutrition, 36 (6). pp. 1520-1529. ISSN 0261-5614 doi: https://doi.org/10.1016/j.clnu.2016.11.013 Serra, Gessica, Deiana, Monica, Spencer, Jeremy P. E. and Corona, Giulia (2017) Olive oil phenolics prevent oxysterol-induced proinflammatory cytokine secretion and reactive oxygen species production in human peripheral blood mononuclear cells, through modulation of p38 and JNK pathways. Molecular Nutrition & Food Research, 61 (12). 1700283. ISSN 1613-4125 doi: https://doi.org/10.1002/mnfr.201700283 Corona, Giulia, Coman, Maria Magdalena, Guo, Yuxuan, Hotchkiss, Sarah, Gill, Chris, Yaqoob, Parveen, Spencer, Jeremy P. E. and Rowland, Ian (2017) Effect of simulated gastrointestinal digestion and fermentation on polyphenolic content and bioactivity of brown seaweed phlorotannin-rich extracts. Molecular Nutrition and Food Research, 61 (11). 1700223. ISSN 1613-4133 doi: https://doi.org/10.1002/mnfr.201700223 Amini, Anna M., Muzs, Karolin, Spencer, Jeremy P. E. and Yaqoob, Parveen (2017) Pelargonidin-3-O-glucoside and its metabolites have modest anti-inflammatory effects in human whole blood cultures. Nutrition Research, 46. pp. 88-95. ISSN 1879-0739 doi: https://doi.org/10.1016/j.nutres.2017.09.006 Saibandith, Bandhita, Spencer, Jeremy, Rowland, Ian R. and Commane, Daniel M. (2017) Olive polyphenols and the metabolic syndrome. Molecules, 22 (7). 1082. ISSN 1420-3049 doi: https://doi.org/10.3390/molecules22071082 Lockyer, Stacey, Rowland, Ian, Spencer, Jeremy Paul Edward, Yaqoob, Parveen and Stonehouse, Welma (2017) Impact of phenolic-rich olive leaf extract on blood pressure, plasma lipids and inflammatory markers: a randomised controlled trial. European Journal of Nutrition, 5 (4). pp. 1421-1432. ISSN 1436-6215 doi: https://doi.org/10.1007/s00394-016-1188-y Vauzour, David, Camprubi-Robles, Maria, Miquel-Kergoat, Sophie, Andres-Lacueva, Cristina, Bánáti, Diána, Barberger-Gateau, Pascale, Bowman, Gene L., Caberlotto, Laura, Clarke, Robert, Hogervorst, Eef, Kiliaan, Amanda J., Lucca, Ugo, Manach, Claudine, Minihane, Anne-Marie, Mitchell, Ellen Siobhan, Perneczky, Robert, Perry, Hugh, Roussel, Anne-Marie, Schuermans, Jeroen, Sijben, John, Spencer, Jeremy P. E., Thuret, Sandrine, van de Rest, Ondine, Vandewoude, Maurits, Wesnes, Keith, Williams, Robert J., Williams, Robin S. B. and Ramirez, Maria (2017) Nutrition for the ageing brain: towards evidence for an optimal diet. Ageing research reviews, 35. pp. 222-240. ISSN 1568-1637 doi: https://doi.org/10.1016/j.arr.2016.09.010 Esteban-Fernández, A., Rendeiro, C., Spencer, J. P. E., Del Coso, D. Gigorro, de Llano, M. D. González, Bartolomé, B. and Moreno-Arribas, M. V. (2017) Neuroprotective effects of selected microbial-derived phenolic metabolites and aroma compounds from wine in human SH-SY5Y neuroblastoma cells and their putative mechanisms of action. Frontiers in Nutrition, 4. 3. ISSN 2296-861X doi: https://doi.org/10.3389/fnut.2017.00003 Sansone, Roberto, Ottaviani, Javier I., Rodriguez-Mateos, Ana, Heinen, Yvonne, Noske, Dorina, Spencer, Jeremy P., Crozier, Alan, Merx, Marc W., Kelm, Malte, Schroeter, Hagen and Heiss, Christian (2017) Methylxanthines enhance the effects of cocoa flavanols on cardiovascular function: randomized, double-masked controlled studies. American Journal of Clinical Nutrition, 105 (2). pp. 352-360. ISSN 0002-9165 doi: https://doi.org/10.3945/ajcn.116.140046 Dong, Honglin, Sargent, Laura J., Chatzidiakou, Yianna, Saunders, Caroline, Harkness, Laura, Bordenave, Nicolas, Rowland, Ian, Spencer, Jeremy P. E. and Lovegrove, Julie A. (2016) Orange pomace fibre increases a composite scoring of subjective ratings of hunger and fullness in healthy adults. Appetite, 107. pp. 478-405. ISSN 0195-6663 doi: https://doi.org/10.1016/j.appet.2016.08.118 Rendeiro, Catarina, Dong, Honglin, Saunders, Caroline, Harkness, Laura, Blaze, Melvin, Hou, Yanpeng, Belanger, Ronald L., Corona, Giulia, Lovegrove, Julie A. and Spencer, Jeremy P. E. (2016) Flavanone-rich citrus beverages counteract the transient decline in postprandial endothelial function in humans: a randomised, controlled, double-masked, cross-over intervention study. British Journal of Nutrition, 116 (12). pp. 1999-2010. ISSN 0007-1145 doi: https://doi.org/10.1017/S0007114516004219 Lamport, Daniel, Pal, Deepa, Macready, Anna, Barbosa Boucas, Sofia, Fletcher, John, Williams, Claire, Spencer, Jeremy and Butler, Laurie (2016) The effects of flavanone-rich citrus juice on cognitive function and cerebral blood flow: an acute, randomised, placebo controlled crossover trial in healthy young adults. British Journal of Nutrition, 116 (12). pp. 2160-2168. ISSN 1475-2662 doi: https://doi.org/10.1017/S000711451600430X Ravishankar, Divyashree, Corona, Giulia, Hogan, Stephanie M., Spencer, Jeremy P. E., Greco, Francesca and Osborn, Helen M. I. (2016) Thioflavones as novel neuroprotective agents. Bioorganic & Medicinal Chemistry, 24 (21). pp. 5513-5520. ISSN 0968-0896 doi: https://doi.org/10.1016/j.bmc.2016.09.006 Alqurashi, Randah M., Galante, Laura A., Rowland, Ian R., Spencer, Jeremy P. and Commane, Danny M. (2016) Consumption of a flavonoid-rich acai meal is associated with acute improvements in vascular function and a reduction in total oxidative status in healthy overweight men. American Journal of Clinical Nutrition, 104 (5). pp. 1227-1235. ISSN 0002-9165 doi: https://doi.org/10.3945/ajcn.115.128728 Alanon, M. E., Castle, S. M., Siswanto, P. J., Cifuentes-Gomez, T. and Spencer, J. P. E. (2016) Assessment of flavanol stereoisomers and caffeine and theobromine content in commercial chocolates. Food Chemistry, 208. pp. 177-184. ISSN 0308-8146 doi: https://doi.org/10.1016/j.foodchem.2016.03.116 Alharbi, Mudi H., Lamport, Daniel J., Dodd, Georgina F., Saunders, Caroline, Harkness, Laura, Butler, Laurie T. and Spencer, Jeremy P. E. (2016) Flavonoid-rich orange juice is associated with acute improvements in cognitive function in healthy middle-aged males. European Journal of Nutrition, 55 (6). pp. 2021-2029. ISSN 1436-6215 doi: https://doi.org/10.1007/s00394-015-1016-9 Ottaviani, Javier I., Borges, Gina, Momma, Tony Y., Spencer, Jeremy P. E., Keen, Carl L., Crozier, Alan and Schroeter, Hagen (2016) The metabolome of [2-(14)C](-)-epicatechin in humans: implications for the assessment of efficacy, safety, and mechanisms of action of polyphenolic bioactives. Scientific reports, 6. 29034. ISSN 2045-2322 doi: https://doi.org/10.1038/srep29034 Dong, Honglin, Rendeiro, Catarina, Kristek, Angelika, Sargent, Laura J., Saunders, Caroline, Harkness, Laura, Rowland, Ian, Jackson, Kim G., Spencer, Jeremy P. E. and Lovegrove, Julie A. (2016) Addition of orange pomace to orange juice attenuates the increases in peak glucose and insulin concentrations after sequential meal ingestion in men with elevated cardiometabolic risk. Journal of Nutrition, 146 (6). pp. 1197-1203. ISSN 1541-6100 doi: https://doi.org/10.3945/jn.115.226001 Corona, Giulia, Ji, Yang, Anegboonlap, Prapaporn, Hotchkiss, Sarah, Gill, Chris, Yaqoob, Parveen, Spencer, Jeremy P. E. and Rowland, Ian (2016) Gastrointestinal modifications and bioavailability of brown seaweed phlorotannins and effects on inflammatory markers. British Journal of Nutrition, 115 (7). pp. 1240-1253. ISSN 1475-2662 doi: https://doi.org/10.1017/S0007114516000210 Neshatdoust, Sara, Saunders, Caroline, Castle, Sophie M., Vauzour, David, Williams, Claire, Butler, Laurie, Lovegrove, Julie A. and Spencer, Jeremy P. E. (2016) High-flavonoid intake induces cognitive improvement linked to changes in serum brain-derived neurotrophic factor: two randomised,controlled trials. Nutrition and Healthy Ageing, 4 (1). pp. 81-93. ISSN 2451-9502 doi: https://doi.org/10.3233/NHA-1615 Lovegrove, Julie A., Commane, Danny M., Jackson, Kim G., Karani, Vimal, Kennedy, Orla B., Kuhnle, Gunter G., Spencer, Jeremy P. E., Wagstaff, Carol and Yaqoob, Parveen (2015) The Hugh Sinclair Unit of Human Nutrition – 20 years of research 1995–2015. Nutrition Bulletin, 40 (4). pp. 303-314. ISSN 1467-3010 doi: https://doi.org/10.1111/nbu.12176 Lamport, Daniel J., Pal, Deepa, Moutsiana, Christina, Field, David T., Williams, Claire M., Spencer, Jeremy P. E. and Butler, Laurie T. (2015) The effect of flavanol-rich cocoa on cerebral perfusion in healthy older adults during conscious resting state: a placebo controlled, crossover, acute trial. Psychopharmacology, 232 (17). pp. 3327-3234. ISSN 0033-3158 doi: https://doi.org/10.1007/s00213-015-3972-4 Heiss, Christian, Sansone, Roberto, Karimi, Hakima, Krabbe, Moritz, Schuler, Dominik, Rodriguez Mateos, Ana, Krämer, Thomas, Cortese-Krott, Miriam M., Kuhnle, Gunter G. C., Spencer, Jeremy P. E., Schroeter, Hagen, Merx, Marc W. and Kelm, Malte (2015) Impact of cocoa flavanol intake on age-dependent vascular stiffness in healthy men: a randomized, controlled, double-masked trial. AGE, 37 (3). 56. ISSN 0161-9152 doi: https://doi.org/10.1007/s11357-015-9794-9 Mills, Charlotte E., Touzonis, Xenofon, Oruna-Concha, Maria-Jose, Mottram, Don S., Gibson, Glenn R. and Spencer, Jeremy P. E. (2015) In vitro colonic metabolism of coffee and chlorogenic acid results in selective changes in human faecal microbiota growth. British Journal of Nutrition, 113 (8). pp. 1220-1227. ISSN 0007-1145 doi: https://doi.org/10.1017/S0007114514003948 Vogiatzoglou, Anna, Mulligan, Angela A., Bhaniani, Amit, Lentjes, Marleen A. H., McTaggart, Alison, Luben, Robert N., Heiss, Christian, Kelm, Malte, Merx, Marc W., Spencer, Jeremy P. E., Schroeter, Hagen, Khaw, Kay-Tee and Kuhnle, Gunter G. C. (2015) Associations between flavan-3-ol intake and CVD risk in the Norfolk cohort of the European Prospective Investigation into Cancer (EPIC-Norfolk). Free Radical Biology and Medicine, 84. pp. 1-10. ISSN 0891-5849 doi: https://doi.org/10.1016/j.freeradbiomed.2015.03.005 Kean, Rebecca J., Lamport, Daniel J., Dodd, Georgina F., Freeman, Jayne, Williams, Claire, Ellis, Judi, Butler, Laurie and Spencer, Jeremy (2015) Chronic consumption of flavanone-rich orange juice is associated with cognitive benefits: an 8-wk randomised, double-blind, placebo-controlled trial in healthy older adults. American Journal of Clinical Nutrition, 101 (3). pp. 506-514. ISSN 0002-9165 doi: https://doi.org/10.3945/ajcn.114.088518 Cifuentes-Gomez, Tania, Rodriguez-Mateos, Ana, Gonzalez-Salvador, Isidro, Alañon, María Elena and Spencer, Jeremy P. E. (2015) Factors affecting the absorption, metabolism, and excretion of cocoa flavanols in humans. Journal of Agricultural and Food Chemistry, 63 (35). pp. 7615-7623. ISSN 1520-5118 doi: https://doi.org/10.1021/acs.jafc.5b00443 Rodriguez-Mateos, Ana, Hezel, Michael, Aydin, Hilal, Kelm, Malte, Lundberg, Jon O., Weitzberg, Eddie, Spencer, Jeremy P. E. and Heiss, Christian (2015) Interactions between cocoa flavanols and inorganic nitrate: additive effects on endothelial function at achievable dietary amounts. Free Radical Biology and Medicine, 80. pp. 121-128. ISSN 0891-5849 doi: https://doi.org/10.1016/j.freeradbiomed.2014.12.009 Sansone, Roberto, Rodriguez-Mateos, Ana, Heuel, Jan, Falk, David, Schuler, Dominik, Wagstaff, Rabea, Kuhnle, Gunter G. C., Spencer, Jeremy P. E., Schroeter, Hagen, Merx, Marc W., Kelm, Malte and Heiss, Christian (2015) Cocoa flavanol intake improves endothelial function and Framingham Risk Score in healthy men and women: a randomised, controlled, double-masked trial: the Flaviola Health Study. British Journal of Nutrition, 114 (8). pp. 1246-1255. ISSN 0007-1145 doi: https://doi.org/10.1017/S0007114515002822 Eid, Noura, Osmanova, Hristina, Natchez, Cecile, Walton, Gemma, Costabile, Adele, Gibson, Glenn, Rowland, Ian and Spencer, Jeremy P.E. (2015) Impact of palm date consumption on microbiota growth and large intestinal health: a randomised, controlled, cross-over, human intervention study. British Journal of Nutrition, 114 (8). pp. 1226-1236. ISSN 1475-2662 doi: https://doi.org/10.1017/S0007114515002780 Lockyer, Stacey, Corona, Giulia, Yaqoob, Parveen, Spencer, Jeremy P E and Rowland, Ian (2015) Secoiridoids delivered as olive leaf extract induce acute improvements in human vascular function and reduction of an inflammatory cytokine: a randomised, double-blind, placebo-controlled, cross-over trial. British Journal of Nutrition, 114 (01). pp. 75-83. ISSN 0007-1145 doi: https://doi.org/10.1017/S0007114515001269 Toro-Funes, Natalia, Morales-Gutiérrez, Francisco Javier, Veciana-Nogués, M. Teresa, Vidal-Carou, M. Carmen, Spencer, Jeremy P. E. and Rodriguez-Mateos, Ana (2015) The intracellular metabolism of isoflavones in endothelial cells. Food & Function, 6 (1). pp. 97-107. ISSN 2042-650X doi: https://doi.org/10.1039/c4fo00772g Lamport, Daniel J, Saunders, Caroline, Butler, Laurie T. and Spencer, Jeremy P. E. (2014) Fruits, vegetables, 100% juice, and cognitive function. Nutrition Reviews, 72 (12). pp. 774-789. ISSN 1753-4887 doi: https://doi.org/10.1111/nure.12149 Eid, Noura, Enani, Sumia, Walton, Gemma, Corona, Giulia, Costabile, Adele, Gibson, Glenn, Rowland, Ian and Spencer, Jeremy P. E. (2014) The impact of date palm fruits and their component polyphenols, on gut microbial ecology, bacterial metabolites and colon cancer cell proliferation. Journal of nutritional science, 3. e46. ISSN 2048-6790 doi: https://doi.org/10.1017/jns.2014.16 Vauzour, David, Pinto, John T., Cooper, Arthur J. L. and Spencer, Jeremy P. E. (2014) The neurotoxicity of 5-S-cysteinyldopamine is mediated by the early activation of ERK1/2 followed by the subsequent activation of ASK1/JNK1/2 pro-apoptotic signalling. Biochemical Journal, 463 (1). pp. 41-52. ISSN 0264-6021 doi: https://doi.org/10.1042/BJ20131519
Rendeiro, Catarina, Foley, Andrew, Lau, Vera C., Ring, Rebecca, Rodriguez-Mateos, Ana, Vauzour, David, Williams, Claire M. de Jager, Celeste A, Dye, Louise, de Bruin, Eveline A, Butler, Laurie, Fletcher, John, Lamport, Daniel J., Latulippe, Marie E, Spencer, Jeremy P. E. and Wesnes, Keith (2014) Criteria for validation and selection of cognitive tests for investigating the effects of foods and nutrients. Nutrition reviews, 72 (3). pp. 162-179. ISSN 1753-4887 doi: https://doi.org/10.1111/nure.12094
Macready, Anna L. Eid, Noura, Walton, Gemma, Costabile, Adele, Kuhnle, Gunter G. C. and Spencer, Jeremy P. E. (2014) Polyphenols, glucosinolates, dietary fibre and colon cancer: Understanding the potential of specific types of fruit and vegetables to reduce bowel cancer progression. Nutrition and Aging, 2 (1). pp. 45-67. ISSN 1879-7725 doi: https://doi.org/10.3233/NUA-130029 Vogiatzoglou, Anna, Mulligan, Angela A., Luben, Robert N., Lentjes, Marleen A. H., Heiss, Christian, Kelm, Malte, Merx, Marc W., Spencer, Jeremy P.E., Schroeter, Hagen and Kuhnle, Gunter G.C. (2013) Assessment of the dietary intake of total flavan-3-ols, monomeric flavan-3-ols, proanthocyanidins and theaflavins in the European Union. British Journal of Nutrition, 111 (08). pp. 1463-1473. ISSN 0007-1145 doi: https://doi.org/10.1017/S0007114513003930 Wright, Bernice, Spencer, Jeremy P. E., Lovegrove, Julie A. and Gibbins, Jonathan M. (2013) Flavonoid inhibitory pharmacodynamics on platelet function in physiological environments. Food & Function, 4 (12). pp. 1803-1810. ISSN 2042-650X doi: https://doi.org/10.1039/C3FO60272A Savignac, Helene M., Corona, Giulia, Mills, Henrietta, Chen, Li, Spencer, Jeremy P E, Tzortzis, George and Burnet, Philip W.J. (2013) Prebiotic feeding elevates central brain derived neurotrophic factor, N-methyl-D-aspartate receptor subunits and D-serine. Neurochemistry International, 63 (8). pp. 756-764. ISSN 0197-0186 doi: https://doi.org/10.1016/j.neuint.2013.10.006 Rendeiro, Catarina, Vauzour, David, Rattray, Marcus, Waffo-Téguo, Pierre, Mérillon, Jean Michel, Butler, Laurie T., Williams, Claire M. and Spencer, Jeremy P. E. (2013) Dietary levels of pure flavonoids improve spatial memory performance and increase hippocampal brain-derived neurotrophic factor. PLoS ONE, 8 (5). e63535. ISSN 1932-6203 doi: https://doi.org/10.1371/journal.pone.0063535 Corona, Giulia, Vauzour, David, Hercelin, Justine, Williams, Claire M. and Spencer, Jeremy P. E. (2013) Phenolic acid intake, delivered via moderate champagne wine consumption, improves spatial working memory via the modulation of hippocampal and cortical protein expression/activation. Antioxidants & Redox Signaling, 19 (4). pp. 1676-1689. ISSN 1523-0864 doi: https://doi.org/10.1089/ars.2012.5142 Chong, Mary Foong-Fong, George, Trevor, Alimbetov, D., Jin, Y., Weech, Michelle, Macready, Anna, Spencer, Jeremy, Kennedy, Orla, Minihane, Anne Marie, Gordon, Mike and Lovegrove, Julie (2013) Impact of the quantity and flavonoid content of fruits and vegetables on markers of intake in adults with an increased risk of cardiovascular disease: the FLAVURS Trial. European Journal of Nutrition, 52 (1). pp. 361-378. ISSN 1436-6215 doi: https://doi.org/10.1007/s00394-012-0343-3 Eid, Noura M. S., Al-Awadi, Balqees, Vauzour, David, Oruna-Concha, Maria Jose and Spencer, Jeremy P. E. (2013) Effect of cultivar type and ripening on the polyphenol content of date palm fruit. Journal of Agricultural and Food Chemistry, 61 (10). pp. 2453-2460. ISSN 0021-8561 doi: https://doi.org/10.1021/jf303951e Wright, Bernice, Spencer, Jeremy P. E., Lovegrove, Julie A. and Gibbins, Jon (2013) Insights into dietary flavonoids as molecular templates for the design of anti-platelet drugs. Cardiovascular Research, 97 (1). pp. 13-22. ISSN 0008-6363 doi: https://doi.org/10.1093/cvr/cvs304 Mills, Charlotte, Oruna-Concha, Maria Jose, Mottram, Donald S., Gibson, Glenn R. and Spencer, Jeremy P. E. (2013) The effect of processing on chlorogenic acid content of commercially available coffee. Food Chemistry, 141 (4). pp. 3335-3340. ISSN 0308-8146 doi: https://doi.org/10.1016/j.foodchem.2013.06.014 Rodriguez Mateos, Ana, Oruna-Concha, Maria Jose, Kwik-Uribe, Catherine, Vidal, Alberto and Spencer, Jeremy P.E. (2012) Influence of sugar type on the bioavailability of cocoa flavanols. British journal of nutrition, 108 (12). pp. 2243-2250. ISSN 1475-2662 doi: https://doi.org/10.1017/S0007114512000475 Rendeiro, Catarina, Vauzour, David, Kean, Rebecca J., Butler, Laurie T., Rattray, Marcus, Spencer, Jeremy P. E. and Williams, Claire M. (2012) Blueberry supplementation induces spatial memory improvements and region-specific regulation of hippocampal BDNF mRNA expression in young rats. Psychopharmacology, 223 (3). pp. 319-330. ISSN 0033-3158 doi: https://doi.org/10.1007/s00213-012-2719-8 Fox, B, Schantz, J. T., Haigh, R., Wood, Mark E., Moore, P. K., Viner, N, Spencer, Jeremy P. E., Winyard, P. G. and Whiteman, M. (2012) Inducible hydrogen sulfide synthesis in chondrocytes and mesenchymal progenitor cells: is H2S a novel cytoprotective mediator in the inflamed joint? Journal of Cellular and Molecular Medicine, 16 (4). pp. 896-910. ISSN 1582-4934 doi: https://doi.org/10.1111/j.1582-4934.2011.01357.x Hidalgo, Maria , Oruna-Concha, M. Jose, Kolida, Sofia, Walton, Gemma E., Kallithraka, Stamatina, Spencer, Jeremy P. E., Gibson, Glenn R. and de Pascual-Teresa, Sonia (2012) Metabolism of anthocyanins by human gut microflora and their influence on gut bacterial growth. Journal of Agricultural and Food Chemistry, 60 (15). pp. 3882-3890. ISSN 0021-8561 doi: https://doi.org/10.1021/jf3002153 Rendeiro, Catarina, Guerreiro, Joao D.T., Williams, Claire and Spencer, Jeremy (2012) Flavonoids as modulators of memory and learning: molecular interactions resulting in behavioural effects. Proceedings of the Nutrition Society, 71 (2). pp. 246-262. ISSN 1475-2719 doi: https://doi.org/10.1017/S0029665112000146 Spilsbury, Alison, Vauzour, David, Spencer, Jeremy P. and Rattray, Marcus (2012) Regulation of NF-κB activity in astrocytes: effects of flavonoids at dietary-relevant concentrations. Biochemical and Biophysical Research Communications, 418. pp. 578-583. ISSN 0006-291X doi: https://doi.org/10.1016/j.bbrc.2012.01.081 Lockyer, Stacey, Yaqoob, Parveen, Spencer, Jeremy and Rowland, Ian (2012) Olive leaf phenolics and cardiovascular risk reduction: Physiological effects and mechanisms of action. Nutrition and Aging, 1 (2). pp. 125-140. ISSN 1879-7725 doi: https://doi.org/10.3233/NUA-2012-0011 Vauzour, David, Corona, Giulia, Hercelin, Justine, Garnotel, Roselyne, Gillery, Philippe, Lovegrove, Julie A., Williams, Claire M. and Spencer, Jeremy P. E. (2011) Potential health effects of Champagne wine consumption. Journal of Wine Research, 22 (2). pp. 175-180. ISSN 1469-9672 doi: https://doi.org/10.1080/09571264.2011.603251 Pinto, Joana, Paiva-Martins, Fátima, Corona, Giulia, Debnam, Edward S., Oruna-Concha, Maria, Vauzour, David, Gordon, Mike and Spencer, Jeremy (2011) Absorption and metabolism of olive oil secoiridoids in the small intestine. British Journal of Nutrition, 105 (11). pp. 1607-1618. ISSN 1475-2662 doi: https://doi.org/10.1017/S000711451000526X Tzounis, X., Rodriguez Mateos, Ana, Vulevic, Jelena, Gibson, Glenn R., Kwik-Uribe, C. and Spencer, Jeremy P. E. (2011) Prebiotic evaluation of cocoa-derived flavanols in healthy humans by using a randomized, controlled, double-blind, crossover intervention study. American Journal of Clinical Nutrition, 93 (1). pp. 62-72. ISSN 1938-3207 doi: https://doi.org/10.3945/ajcn.110.000075 Vauzour, D., Houseman, E.J., George, T.W., Corona, G., Garnotel, R., Jackson, K.G., Sellier, C., Gillery, P., Kennedy, O.B., Lovegrove, J.A. and Spencer, J.P.E. (2010) Moderate Champagne consumption promotes an acute improvement in acute endothelial-independent vascular function in healthy human volunteers. British Journal of Nutrition, 103 (8). pp. 1168-1178. ISSN 0007-1145 doi: https://doi.org/10.1017/S0007114509992959 Wright, Bernice, Gibson, Trevor, Spencer, Jeremy, Lovegrove, Julie A. and Gibbins, Jonathan M. (2010) Platelet-mediated metabolism of the common dietary flavonoid, quercetin. PLoS ONE, 5 (3). e9673. ISSN 1932-6203 doi: https://doi.org/10.1371/journal.pone.0009673 Spencer, Jeremy Paul (2010) Beyond antioxidants: the cellular and molecular interactions of flavonoids and how these underpin their actions on the brain. Proceedings of the Nutrition Society, 69 (2). pp. 244-260. ISSN 0029-6651 doi: https://doi.org/10.1017/S0029665110000054 Vauzour, David, Corona, Giulia and Spencer, Jeremy Paul (2010) Caffeic acid, tyrosol and p-coumaric acid are potent inhibitors of 5-S-cysteinyl-dopamine induced neurotoxicity. Archives of Biochemistry and Biophysics, 501 (1). pp. 106-111. ISSN 0003-9861 doi: https://doi.org/10.1016/j.abb.2010.03.016 Macready, Anna L., Butler, Laurie T., Kennedy, Orla B., Ellis, Judith A., Williams, Claire M. and Spencer, Jeremy P. (2010) Cognitive tests used in chronic adult human randomised controlled trial micronutrient and phytochemical intervention studies. Nutrition Research Reviews, 23 (2). pp. 200-229. ISSN 0954-4224 doi: https://doi.org/10.1017/S0954422410000119 Incani, A., Deiana, M., Corona, Giulia, Vafeiadou, Katerina, Vauzour, David, Dessi, M. A. and Spencer, Jeremy (2010) Involvement of ERK, Akt and JNK signalling in H2O2-induced cell injury and protection by hydroxytyrosol and its metabolite homovanillic alcohol. Molecular Nutrition & Food Research, 54 (6). pp. 788-796. ISSN 1613-4125 doi: https://doi.org/10.1002/mnfr.200900098 Schroeter, H., Heiss, C., Spencer, Jeremy P. E., Keen, C. L., Lupton, J. R. and Schmitz, H. H. (2010) Recommending flavanols and procyanidins for cardiovascular health: current knowledge and future needs. Molecular Aspects of Medicine, 31 (6). pp. 546-557. ISSN 0098-2997 doi: https://doi.org/10.1016/j.mam.2010.09.008 Vauzour, David, Buonfiglio, M., Corona, Giulia, Chirafisi, J., Vafeiadou, Katerina, Angeloni, C., Hrelia, S., Hrelia, P. and Spencer, Jeremy P E (2010) Sulforaphane protects cortical neurons against 5-S-cysteinyl-dopamine-induced toxicity through the activation of ERK1/2, Nrf-2 and the upregulation of detoxification enzymes. Molecular Nutrition & Food Research, 54 (4). pp. 532-542. ISSN 1613-4125 doi: https://doi.org/10.1002/mnfr.200900197 Spencer, Jeremy P. (2010) The impact of fruit flavonoids on memory and cognition. British Journal of Nutrition, 104 (Supple). S40-S47. ISSN 0007-1145 doi: https://doi.org/10.1017/S0007114510003934 Frank, J., George, T. W., Lodge, J. K., Rodriguez-Mateos, A. M., Spencer, J. P. E., Minihane, A. M. and Rimbach, G. (2009) Daily consumption of an aqueous green tea extract supplement does not impair liver function or alter cardiovascular disease risk biomarkers in healthy men. Journal of Nutrition, 139 (1). pp. 58-62. ISSN 0022-3166 doi: https://doi.org/10.3945/jn.108.096412 Corona, G., Spencer, J. P. E. and Dessi, M. A. (2009) Extra virgin olive oil phenolics: absorption, metabolism, and biological activities in the GI tract. Toxicology and Industrial Health, 25 (4-5). pp. 285-293. ISSN 0748-2337 doi: https://doi.org/10.1177/0748233709102951 Spencer, J. P. E. (2009) Flavonoids and brain health: multiple effects underpinned by common mechanisms. Genes and Nutrition, 4 (4). pp. 243-250. ISSN 1555-8932 doi: https://doi.org/10.1007/s12263-009-0136-3 Spencer, J. P. E., Vauzour, D. and Rendeiro, C. (2009) Flavonoids and cognition: The molecular mechanisms underlying their behavioural effects. Archives of Biochemistry and Biophysics, 492 (1-2). pp. 1-9. ISSN 0003-9861 doi: https://doi.org/10.1016/j.abb.2009.10.003 Macready, Anna L., Kennedy, O. B., Ellis, J. A., Williams, C. M., Spencer, J. P. E. and Butler, L. T. (2009) Flavonoids and cognitive function: a review of human randomized controlled trial studies and recommendations for future studies. Genes and Nutrition, 4 (4). pp. 227-242. ISSN 1555-8932 doi: https://doi.org/10.1007/s12263-009-0135-4 Corona, G., Deiana, M., Incani, A., Vauzour, D., Dessi, M. A. and Spencer, J. P. E. (2009) Hydroxytyrosol inhibits the proliferation of human colon adenocarcinoma cells through inhibition of ERK1/2 and cyclin D1. Molecular Nutrition & Food Research, 53 (7). pp. 897-903. ISSN 1613-4125 doi: https://doi.org/10.1002/mnfr.200800269 Spencer, J. P. E. (2009) Nutrients and brain health: an overview. Genes and Nutrition, 4 (4). pp. 225-226. ISSN 1555-8932 doi: https://doi.org/10.1007/s12263-009-0140-7 Vafeiadou, K., Vauzour, D., Lee, H. Y., Rodriguez-Mateos, A., Williams, R. J. and Spencer, J. P. E. (2009) The citrus flavanone naringenin inhibits inflammatory signalling in glial cells and protects against neuroinflammatory injury. Archives of Biochemistry and Biophysics, 484 (1). pp. 100-109. ISSN 0003-9861 doi: https://doi.org/10.1016/j.abb.2009.01.016 Spencer, J. P. E. (2009) The impact of flavonoids on memory: physiological and molecular considerations. Chemical Society Reviews, 38 (4). pp. 1152-1161. ISSN 0306-0012 doi: https://doi.org/10.1039/b800422f Rendeiro, C., Spencer, J. P. E., Vauzour, D., Butler, L. T., Ellis, J. A. and Williams, C. M. (2009) The impact of flavonoids on spatial memory in rodents: from behaviour to underlying hippocampal mechanisms. Genes and Nutrition, 4 (4). pp. 251-270. ISSN 1555-8932 doi: https://doi.org/10.1007/s12263-009-0137-2 Spencer, J. P. E., Mohsen, M. M. A., Minihane, A. M. and Mathers, J. C. (2008) Biomarkers of the intake of dietary polyphenols: strengths, limitations and application in nutrition research. British Journal of Nutrition, 99 (1). pp. 12-22. ISSN 0007-1145 doi: https://doi.org/10.1017/s0007114507798938 Williams, C. M., El Mohsen, M. A., Vauzour, D., Rendeiro, C., Butler, L. T., Ellis, J. A., Whiteman, M. and Spencer, Jeremy P. E. (2008) Blueberry-induced changes in spatial working memory correlate with changes in hippocampal CREB phosphorylation and brain-derived neurotrophic factor (BDNF) levels. Free Radical Biology and Medicine, 45 (3). pp. 295-305. ISSN 1873-4596 doi: https://doi.org/10.1016/j.freeradbiomed.2008.04.008 Whiteman, M., Spencer, J. P. E., Szeto, H. H. and Armstrong, J. S. (2008) Do mitochondriotropic antioxidants prevent chlorinative stress-induced mitochondrial and cellular injury? Antioxidants & Redox Signaling, 10 (3). pp. 641-650. ISSN 1523-0864 doi: https://doi.org/10.1089/ars.2007.1879 Tzounis, X., Vulevic, J., Kuhnle, G. G. C., George, T., Leonczak, J., Gibson, G. R., Kwik-Uribe, C. and Spencer, J. P. E. (2008) Flavanol monomer-induced changes to the human faecal microflora. British Journal of Nutrition, 99 (4). pp. 782-792. ISSN 0007-1145 doi: https://doi.org/10.1017/s0007114507853384 Spencer, J.P.E. (2008) Food for thought: the role of dietary flavonoids in enhancing human memory, learning and neuro-cognitive performance. Proceedings of the Nutrition Society, 67 (2). pp. 238-252. ISSN 0029-6651 doi: https://doi.org/10.1017/s0029665108007088 Vafeiadou, K., Vauzour, D., Rodriguez-Mateos, A., Whiteman, M., Williams, R. J. and Spencer, J. P. E. (2008) Glial metabolism of quercetin reduces its neurotoxic potential. Archives of Biochemistry and Biophysics, 478 (2). pp. 195-200. ISSN 0003-9861 doi: https://doi.org/10.1016/j.abb.2008.07.014 Whiteman, M. and Spencer, J. P. E. (2008) Loss of 3-chlorotyrosine by inflammatory oxidants: Implications for the use of 3-chlorotyrosine as a bio-marker in vivo. Biochemical and Biophysical Research Communications, 371 (1). pp. 50-53. ISSN 0006-291X doi: https://doi.org/10.1016/j.bbrc.2008.03.153 Rainey-Smith, S., Schroetke, L.W., Bahia, P., Fahmi, A., Skilton, R., Spencer, J.P.E., Rice-Evans, C., Rattray, M. and Williams, R.J. (2008) Neuroprotective effects of hesperetin in mouse primary neurones are independent of CREB activation. Neuroscience Letters, 438 (1). pp. 29-33. ISSN 0304-3940 doi: https://doi.org/10.1016/j.neulet.2008.04.056 Vauzour, D., Ravaioli, G., Vafeiadou, K., Rodriguez-Mateos, A., Angeloni, C. and Spencer, J. P. E. (2008) Peroxynitrite induced formation of the neurotoxins 5-S-cysteinyl-dopamine and DHBT-1: implications for Parkinson's disease and protection by polyphenols. Archives of Biochemistry and Biophysics, 476 (2). pp. 145-151. ISSN 0003-9861 doi: https://doi.org/10.1016/j.abb.2008.03.011 Cooper, A. J. L., Pinto, J. T., Krasnikov, B. F., Niatsetskaya, Z. V., Han, Q., Li, J. Y., Vauzour, D. and Spencer, J. P. E. (2008) Substrate specificity of human glutamine transaminase K as an aminotransferase and as a cysteine S-conjugate beta-lyase. Archives of Biochemistry and Biophysics, 474 (1). pp. 72-81. ISSN 0003-9861 doi: https://doi.org/10.1016/j.abb.2008.02.038 Vauzour, D., Vafeiadou, K., Rodriguez-Mateos, A., Rendeiro, C. and Spencer, J.P.E. (2008) The neuroprotective potential of flavonoids: a multiplicity of effects. Genes and Nutrition, 3 (3-4). pp. 115-126. ISSN 1555-8932 doi: https://doi.org/10.1007/s12263-008-0091-4 Vauzour, D., Vafeiadou, K., Rice-Evans, C., Williams, R. J. and Spencer, J. P. E. (2007) Activation of pro-survival Akt and ERK1/2 signalling pathways underlie the anti-apoptotic effects of flavanones in cortical neurons. Journal of Neurochemistry, 103 (4). pp. 1355-1367. ISSN 0022-3042 doi: https://doi.org/10.1111/j.1471-4159.2007.04841.x Vauzour, D., Vafeiadou, K., Corona, G., Pollard, S. E., Tzounis, X. and Spencer, J. P. E. (2007) Champagne wine polyphenols protect primary cortical neurons against peroxynitrite-induced injury. Journal of Agricultural and Food Chemistry, 55 (8). pp. 2854-2860. ISSN 0021-8561 doi: https://doi.org/10.1021/jf063304z Schroeter, H., Bahia, P., Spencer, J.P.E., Sheppard, O., Rattray, M., Cadenas, E., Rice-Evans, C. and Williams, R.J. (2007) (-)Epicatechin stimulates ERK-dependent cyclic AMP response element activity and up-regulates GluR2 in cortical neurons. Journal of Neurochemistry, 101 (6). pp. 1596-1606. ISSN 0022-3042 doi: https://doi.org/10.1111/j.1471-4159.2006.04434.x Vauzour, D., Vafeiadou, K., Rice-Evans, C., Cadenas, E. and Spencer, J. P. E. (2007) Inhibition of cellular proliferation by the genistein metabolite 5,7,3',4'-tetrahydroxyisoflavone is mediated by DNA damage and activation of the ATR signalling pathway. Archives of Biochemistry and Biophysics, 468 (2). pp. 159-166. ISSN 0003-9861 doi: https://doi.org/10.1016/j.abb.2007.09.021 Corona, G., Deiana, M., Incani, A., Vauzour, D., Dessi, M.A. and Spencer, J.P.E. (2007) Inhibition of p38/CREB phosphorylation and COX-2 expression by olive oil polyphenols underlies their anti-proliferative effects. Biochemical and Biophysical Research Communications, 362 (3). pp. 606-611. ISSN 0006-291X doi: https://doi.org/10.1016/j.bbrc.2007.08.049 Vauzour, D., Vafeiadou, K. and Spencer, J. P. E. (2007) Inhibition of the formation of the neurotoxin 5-S-cysteinyl-dopamine by polyphenols. Biochemical and Biophysical Research Communications, 362 (2). pp. 340-346. ISSN 0006-291X doi: https://doi.org/10.1016/j.bbrc.2007.07.153 Vafeiadou, K., Vauzour, D. and Spencer, J. P. E. (2007) Neuroinflammation and its modulation by flavonoids. Endocrine, Metabolic & Immune Disorders - Drug Targets, 7 (3). pp. 211-224. ISSN 2212-3873 Angeloni, C., Spencer, J.P.E., Leoncini, E., Biagi, P.L. and Hrelia, S. (2007) Role of quercetin and its in vivo metabolites in protecting H9c2 cells against oxidative stress. Biochimie, 89 (1). pp. 73-82. ISSN 0300-9084 doi: https://doi.org/10.1016/j.biochi.2006.09.006 Spencer, J.P.E. (2007) The interactions of flavonoids within neuronal signalling pathways. Genes and Nutrition, 2 (3). pp. 257-273. ISSN 1555-8932 doi: https://doi.org/10.1007/s12263-007-0056-z Whiteman, M., Chu, S. H., Siau, J. L., Rose, P., Sabapathy, K., Schantz, J. T., Cheung, N. S., Spencer, J.P.E. and Armstrong, J. S. (2007) The pro-inflammatory oxidant hypochlorous acid induces Bax-dependent mitochondrial permeabilisation and cell death through AIF-/EndoG-dependent pathways. Cellular Signalling, 19 (4). pp. 705-714. ISSN 0898-6568 doi: https://doi.org/10.1016/j.cellsig.2006.08.019 El Mohsen, M.A., Marks, J., Kuhnle, Gunter, Moore, K., Debnam, E., Srai, S.K., Rice-Evans, C. and Spencer, Jeremy (2006) Absorption, tissue distribution and excretion of pelargonidin and its metabolites following oral administration to rats. British Journal of Nutrition, 95 (1). pp. 51-58. ISSN 1475-2662 doi: https://doi.org/10.1079/BJN20051596 Hernandez-Montes, E., Pollard, S.E., Vauzour, D., Jofre-Montseny, L., Rota, C., Rimbach, G., Weinberg, P.D. and Spencer, J.P.E. (2006) Activation of glutathione peroxidase via Nrf1 mediates genistein's protection against oxidative endothelial cell injury. Biochemical and Biophysical Research Communications, 346 (3). pp. 851-859. ISSN 0006-291X doi: https://doi.org/10.1016/j.bbrc.2006.05.197 El Mohsen, M.A., Bayele, H., Kuhnle, G., Gibson, G., Debnam, E., Srai, S.K., Rice-Evans, C. and Spencer, J.P.E. (2006) Distribution of [H-3]trans-resveratrol in rat tissues following oral administration. British Journal of Nutrition, 96 (1). pp. 62-70. ISSN 0007-1145 doi: https://doi.org/10.1079/bjn20061810 Spencer, J.P.E., Abd El Mohsen, M. and Minihane, A.M. (2006) Metabolism of dietary phytochemicals: a review of the metabolic forms identified in humans. Current Topics in Nutraceutical Research, 4 (3-4). pp. 187-203. ISSN 1540-7535 Pollard, S. E., Whiteman, M. and Spencer, J. P. E. (2006) Modulation of peroxynitrite-induced fibroblast injury by hesperetin: a role for intracellular scavenging and modulation of ERK signalling. Biochemical and Biophysical Research Communications, 347 (4). pp. 916-923. ISSN 0006-291X doi: https://doi.org/10.1016/j.bbrc.2006.06.153 Whiteman, M., Spencer, J.P.E., Zhu, Y.Z., Armstrong, J.S. and Schantz, J.T. (2006) Peroxynitrite-modified collagen-II induces p38/ERK and NF-kappa B-dependent synthesis of prostaglandin E-2 and nitric oxide in chondrogenically differentiated mesenchyrnal progenitor cells. Osteoarthritis and Cartilage, 14 (5). pp. 460-470. ISSN 1063-4584 doi: https://doi.org/10.1016/j.joca.2005.11.002 Corona, G., Tzounis, X., Dessi, M.A., Deiana, M., Debnam, E.S., Visioli, F. and Spencer, J.P.E. (2006) The fate of olive oil polyphenols in the gastrointestinal tract: implications of gastric and colonic microflora-dependent biotransformation. Free Radical Research, 40 (6). pp. 647-658. ISSN 1071-5762 doi: https://doi.org/10.1080/10715760500373000 Nguyen, D.T., Hemandez-Montes, E., Vauzour, D., Schonthal, A.H., Rice-Evans, C., Cadenas, E. and Spencer, J.P.E. (2006) The intracellular genistein metabolite 5,7,3 ',4 '-tetrahydroxyisoflavone mediates G2-M cell cycle arrest in cancer cells via modulation of the p38 signaling pathway. Free Radical Biology and Medicine, 41 (8). pp. 1225-1239. ISSN 0891-5849 doi: https://doi.org/10.1016/j.freeradbiomed.2006.06.026 Lee, S.Y.H., Munerol, B., Pollard, S., Youdim, K.A., Pannala, A.S., Kuhnle, G.G.C., Debnam, E.S., Rice-Evans, C. and Spencer, J.P.E. (2006) The reaction of flavanols with nitrous acid protects against N-nitrosamine formation and leads to the formation of nitroso derivatives which inhibit cancer cell growth. Free Radical Biology and Medicine, 40 (2). pp. 323-334. ISSN 0891-5849 doi: https://doi.org/10.1016/j.freeradbiomed.2005.08.031 Pollard, S.E., Kuhnle, G.G.C., Vauzour, D., Vafeiadou, K., Tzounis, X., Whiteman, M., Rice-Evans, C. and Spencer, J.P.E. (2006) The reaction of flavonoid metabolites with peroxynitrite. Biochemical and Biophysical Research Communications, 350 (4). pp. 960-968. ISSN 0006-291X doi: https://doi.org/10.1016/j.bbrc.2006.09.131 El Mohsen, M.M.A., Iravani, M.M., Spencer, J.P.E., Rose, S., Fahim, A.T., Motawi, T.M.K., Ismail, N.A.F. and Jenner, P. (2005) Age-associated changes in protein oxidation and proteasome activities in rat brain: modulation by antioxidants. Biochemical and Biophysical Research Communications, 336 (2). pp. 386-391. ISSN 0006-291X doi: https://doi.org/10.1016/j.bbrc.2005.07.201 Spencer, J. P. E., Kuhnle, G. G. C., Hajirezaei, M., Mock, H. P., Sonnewald, U. and Rice-Evans, C. (2005) The genotypic variation of the antioxidant potential of different tomato varieties. Free Radical Research, 39 (9). pp. 1005-1016. ISSN 1071-5762 doi: https://doi.org/10.1080/10715760400022293 Spencer, J. P. E., El Mohsen, M. M. A. and Rice-Evans, C. (2004) Cellular uptake and metabolism of flavonoids and their metabolites: implications for their bioactivity. Archives of Biochemistry and Biophysics, 423 (1). pp. 148-161. ISSN 0003-9861 doi: https://doi.org/10.1016/j.abb.2003.11.010 Tortarolo, M., Crossthwaite, A.J., Conforti, L., Spencer, J.P.E., Williams, R.J. , Bendotti, C. and Rattray, M. (2004) Expression of SOD1 G93A or wild-type SOD1 in primary cultures of astrocytes down-regulates the glutamate transporter GLT-1: lack of involvement of oxidative stress. Journal of Neurochemistry, 88 (2). pp. 481-493. ISSN 0022-3042 doi: https://doi.org/10.1046/j.1471-4159.2003.02208.x Williams, R.J., Spencer, J.P.E. and Rice-Evans, C. (2004) Flavonoids: antioxidants or signalling molecules? Free Radical Biology and Medicine, 36 (7). pp. 838-849. ISSN 0891-5849 doi: https://doi.org/10.1016/j.freeradbiomed.2004.01.001 Williams, R.J., Spencer, J.P.E., Goni, F.M. and Rice-Evans, C.A. (2004) Zinc-histidine complex protects cultured cortical neurons against oxidative stress-induced damage. Neuroscience Letters, 371 (2-3). pp. 106-110. ISSN 0304-3940 doi: https://doi.org/10.1016/j.neulet.2004.08.054 Basu-Modak, S., Gordon, M.J., Dobson, L.H., Spencer, Jeremy, Rice-Evans, C. and Tyrrell, R.M. (2003) Epicatechin and its methylated metabolite attenuate UVA-induced oxidative damage to human skin fibroblasts. Free Radical Biology and Medicine, 35 (8). pp. 910-921. ISSN 0891-5849 doi: https://doi.org/10.1016/S0891-5849(03)00436-2 Spencer, Jeremy (2003) Metabolism of tea flavonoids in the gastrointestinal tract. Journal of Nutrition, 133 (10). 3255S-3261S. ISSN 1541-6100 Spencer, Jeremy, Rice-Evans, C. and Williams, R.J. (2003) Modulation of pro-survival Akt/protein kinase B and ERK1/2 signaling cascades by quercetin and its in vivo metabolites underlie their action on neuronal viability. The Journal of Biological Chemistry, 278 (37). pp. 34783-34793. ISSN 1083-351X doi: https://doi.org/10.1074/jbc.M305063200 Schroeter, H., Boyd, C., Ahmed, R., Spencer, Jeremy, Duncan, R., Rice-Evans, C. and Cadenas, E. (2003) c-Jun N-terminal kinase (JNK)-mediated modulation of brain mitochondria function: new target proteins for JNK signalling in mitochondrion-dependent apoptosis. Biochemical Journal, 372 (2). pp. 359-369. ISSN 0264-6021 doi: https://doi.org/10.1042/BJ20030201 Spencer, Jeremy, Kuhnle, Gunter G., Williams, R.J. and Rice-Evans, C. (2003) Intracellular metabolism and bioactivity of quercetin and its in vivo metabolites. Biochemical Journal, 372 (1). pp. 173-181. ISSN 0264-6021 doi: https://doi.org/10.1042/BJ20021972 Book or Report SectionEsteban-Fernández, Adelaida, Corona, Giulia, Vauzour, David and Spencer, Jeremy P. E. (2016) Neuroprotective effects associated with wine and its phenolic constituents. In: Moreno-Arribas, M. Victoria and Bartolomé Suáldea, Begoña (eds.) Wine Safety, Consumer Preference, and Human Health. Springer, pp. 279-292. ISBN 9783319245126 doi: https://doi.org/10.1007/978-3-319-24514-0_14 Vauzour, David, Spilsbury, Alison, Vafeiadou, Katerina, Rattray, Marcus and Spencer, Jeremy (2012) Modulation of neuroinflammation by dietary flavonoids. In: Gemma, Carmelina (ed.) Neuroinflammation: Pathogenesis, Mechanisms and Management. Nova, pp. 213-236. ISBN 9781619424623 Conference or Workshop ItemEsteban-Fernández, A., Gigorro del Coso, D., González de Llano, D., Spencer, Jeremy, Bartolomé, B. and Moreno-Arribas, M. V. (2016) Understanding the protective effects of wine components and their metabolites in the brain function. In: 39th World Congress of Vine and Wine, 23 - 28 Oct 2016, Bento Gonçalves, Brazil, 04008. doi: https://doi.org/10.1051/bioconf/20160704008 |
