Article

Krenkel, Henriette, Brown, Jeffery, Morris, Michael and Cramer, Rainer ORCID: https://orcid.org/0000-0002-8037-2511 (2023) The use of salts, buffers and surfactants in LAP-MALDI MS. International Journal of Mass Spectrometry, 493. 117314. ISSN 1873-2798 doi: https://doi.org/10.1016/j.ijms.2023.117134

Lellman, Sophie E., Reynolds, Christopher K. ORCID: https://orcid.org/0000-0002-4152-1190, Jones, A. K. Barney, Taylor, Nick and Cramer, Rainer ORCID: https://orcid.org/0000-0002-8037-2511 (2023) LAP-MALDI MS profiling and identification of potential biomarkers for the detection of bovine tuberculosis. Journal of Agricultural and Food Chemistry, 71 (37). pp. 13899-13905. ISSN 1520-5118 doi: https://doi.org/10.1021/acs.jafc.3c01879

Challen, Bob, Morris, Michael and Cramer, Rainer ORCID: https://orcid.org/0000-0002-8037-2511 (2023) Ultra-high-throughput and low-volume analysis of intact proteins with LAP-MALDI MS. Journal of the American Society for Mass Spectrometry, 34 (6). pp. 991-994. ISSN 1879-1123 doi: https://doi.org/10.1021/jasms.3c00068

Challen, Bob and Cramer, Rainer ORCID: https://orcid.org/0000-0002-8037-2511 (2022) Advances in ionisation techniques for mass spectrometry‐based omics research. Proteomics, 22 (15-16). 2100394. ISSN 1615-9853 doi: https://doi.org/10.1002/pmic.202100394

Krenkel, Henriette, Brown, Jeffery, Richardson, Keith, Hoyes, Emmy, Morris, Michael and Cramer, Rainer ORCID: https://orcid.org/0000-0002-8037-2511 (2022) Ultrahigh-throughput sample analysis using liquid atmospheric pressure matrix-assisted laser desorption/ionization mass spectrometry. Analytical Chemistry, 94 (10). pp. 4141-4145. ISSN 0003-2700 doi: https://doi.org/10.1021/acs.analchem.1c05614

Piras, Cristian, Hale, Oliver J., Reynolds, Christopher K. ORCID: https://orcid.org/0000-0002-4152-1190, Jones, A. K. (Barney), Taylor, Nick, Morris, Michael and Cramer, Rainer ORCID: https://orcid.org/0000-0002-8037-2511 (2022) LAP-MALDI MS coupled with machine learning: an ambient mass spectrometry approach for high-throughput diagnostics. Chemical Science, 13 (6). pp. 1746-1758. ISSN 1478-6524 doi: https://doi.org/10.1039/D1SC05171G

Piras, Cristian, Hale, Oliver J., Reynolds, Christopher K. ORCID: https://orcid.org/0000-0002-4152-1190, Jones, A. K., Taylor, Nick, Morris, Michael and Cramer, Rainer ORCID: https://orcid.org/0000-0002-8037-2511 (2021) Speciation and milk adulteration analysis by rapid ambient liquid MALDI mass spectrometry profiling using machine learning. Scientific Reports, 11 (1). 3305. ISSN 2045-2322 doi: https://doi.org/10.1038/s41598-021-82846-5

Hale, Oliver J., Ryumin, Pavel, Brown, Jeffery M., Morris, Michael and Cramer, Rainer ORCID: https://orcid.org/0000-0002-8037-2511 (2020) Production and analysis of multiply charged negative ions by liquid atmospheric pressure matrix-assisted laser desorption/ionization mass spectrometry. Rapid Communications in Mass Spectrometry, 35 (S1). ISSN 1097-0231 doi: https://doi.org/10.1002/rcm.8246

Piras, Cristian, Greco, Viviana, Gugliandolo, Enrico, Soggiu, Alessio, Tilocca, Bruno, Bonizzi, Luigi, Zecconi, Alfonso, Cramer, Rainer ORCID: https://orcid.org/0000-0002-8037-2511, Britti, Domenico, Urbani, Andrea and Roncada, Paola (2020) Raw cow milk bacterial consortium as bioindicator of circulating anti-microbial resistance (AMR). Animal Feed Science and Technology, 10 (12). 2378. ISSN 0377-8401 doi: https://doi.org/10.3390/ani10122378

Cramer, Rainer (2020) High-speed analysis of large sample sets – how can this key aspect of the omics be achieved? Molecular and Cellular Proteomics, 19 (11). pp. 1760-1766. ISSN 1535-9484 doi: https://doi.org/10.1074/mcp.P120.001997

Castelletto, Valeria, Seitsonen, Jani, Ruokolainen, Janne, Piras, Cristian, Cramer, Rainer, Edwards-Gayle, Charlotte J. C. and Hamley, Ian W. (2020) Peptide nanotubes self-assembled from leucine-rich alpha helical surfactant-like peptides. Chemical Communications, 56 (80). pp. 11977-11980. ISSN 1359-7345 doi: https://doi.org/10.1039/D0CC04299D

Piras, Cristian, Ceniti, Carlotta, Hartmane, Evita, Costanzo, Nicola, Morittu, Valeria Maria, Roncada, Paola, Britti, Domenico and Cramer, Rainer (2020) Rapid liquid AP-MALDI MS profiling of lipids and proteins from goat and sheep milk for speciation and colostrum analysis. Proteomes, 8 (3). 20. ISSN 2227-7382 doi: https://doi.org/10.3390/proteomes8030020

Scollo, Emanuele, Neville, David C. A., Oruna-Concha, M. Jose, Trotin, Martine, Umaharan, Pathmanathan, Sukha, Darin, Kalloo, Rena and Cramer, Rainer (2020) Proteomic and peptidomic UHPLC-ESI MS/MS analysis of cocoa beans fermented using the Styrofoam-box method. Food Chemistry, 316. 126350. ISSN 0308-8146 doi: https://doi.org/10.1016/j.foodchem.2020.126350

Krenkel, Henriette, Hartmane, Evita, Piras, Cristian, Brown, Jeffery, Morris, Michael and Cramer, Rainer (2020) Advancing liquid atmospheric pressure matrix-assisted laser desorption/ionization mass spectrometry toward ultra-high-throughput analysis. Analytical Chemistry, 92 (4). pp. 2931-2936. ISSN 0003-2700 doi: https://doi.org/10.1021/acs.analchem.9b05202

Scollo, Emanuele, Neville, David C. A., Oruna-Concha, M. Jose, Trotin, Martine and Cramer, Rainer (2020) UHPLC-MS/MS analysis of cocoa bean proteomes from four different genotypes. Food Chemistry, 303. 125244. ISSN 0308-8146 doi: https://doi.org/10.1016/j.foodchem.2019.125244

Lambertucci, Sebastien, Orman, Kate Mary, Das Gupta, Shaoli, Fisher, James Paul, Gazal, Snehi, Williamson, Ryan Joshua, Cramer, Rainer and Bindschedler, Laurence Véronique (2019) Analysis of barley leaf epidermis and extrahaustorial proteomes during powdery mildew infection reveals that the PR5 thaumatin-like protein TLP5 is required for susceptibility towards Blumeria graminis f. sp. hordei. Frontiers in Plant Science, 10. 1138. ISSN 1664-462X doi: https://doi.org/10.3389/fpls.2019.01138

Hale, Oliver J., Morris, Michael, Jones, Barney, Reynolds, Christopher K. and Cramer, Rainer (2019) Liquid atmospheric pressure matrix-assisted laser desorption/ionization mass spectrometry adds enhanced functionalities to MALDI MS profiling for disease diagnostics. ACS Omega, 4 (7). pp. 12759-12765. ISSN 2470-1343 doi: https://doi.org/10.1021/acsomega.9b01476

Lellman, Sophie E. and Cramer, Rainer (2019) Bacterial identification by lipid profiling using liquid atmospheric pressure matrix-assisted laser desorption/ionization mass spectrometry. Clinical Chemistry and Laboratory Medicine, 58 (6). pp. 930-938. ISSN 1437-4331 doi: https://doi.org/10.1515/cclm-2019-0908

Hale, Oliver and Cramer, Rainer (2019) Atmospheric pressure ultraviolet laser desorption and ionization from liquid samples for native mass spectrometry. Analytical Chemistry, 91 (22). pp. 14192-14197. ISSN 0003-2700 doi: https://doi.org/10.1021/acs.analchem.9b03875

Hutchinson, Jessica A., Hamley, Ian W., Edwards-Gayle, Charlotte J. C., Castelletto, Valeria, Piras, Cristian, Cramer, Rainer, Kowalczyk, Radoslaw, Seitsonen, Jani, Ruokolainen, Janne and Rambo, Robert P. (2019) Melanin production by tyrosinase activity on a tyrosine-rich peptide fragment and pH-dependent self-assembly of its lipidated analogue. Organic & Biomolecular Chemistry, 17. pp. 4543-4553. ISSN 1477-0520 doi: https://doi.org/10.1039/C9OB00550A

Ryumin, Pavel and Cramer, Rainer (2018) The composition of liquid atmospheric pressure matrix-assisted laser desorption/ionization matrices and its effect on ionization in mass spectrometry. Analytica Chimica Acta, 1013. pp. 43-53. ISSN 1873-4324 doi: https://doi.org/10.1016/j.aca.2018.01.070

Scollo, Emanuele, Neville, David, Oruna-Concha, M. Jose ORCID: https://orcid.org/0000-0001-7916-1592, Trotin, Martine and Cramer, Rainer ORCID: https://orcid.org/0000-0002-8037-2511 (2018) Characterization of the proteome of Theobroma cacao beans by nano-UHPLC-ESI MS/MS. Proteomics, 18 (3-4). 1700339. ISSN 1615-9853 doi: https://doi.org/10.1002/pmic.201700339

Hale, Oliver J. and Cramer, Rainer (2018) Collision-induced dissociation of doubly-charged barium-cationized lipids generated from liquid samples by atmospheric pressure matrix-assisted laser desorption/ionization provides structurally diagnostic product ions. Analytical and Bioanalytical Chemistry, 410 (5). pp. 1435-1444. ISSN 1618-2650 doi: https://doi.org/10.1007/s00216-017-0788-6

Torma, Attila F., Groves, Kate, Biesenbruch, Sabine, Mussell, Chris, Reid, Alan, Ellison, Steve, Cramer, Rainer and Quaglia, Milena (2017) A candidate liquid chromatography mass spectrometry reference method for the quantification of the cardiac marker 1-32 B-type natriuretic peptide. Clinical Chemistry and Laboratory Medicine, 55 (9). pp. 1434-6621. ISSN 1437-4331 doi: https://doi.org/10.1515/cclm-2016-1054

Ryumin, Pavel, Brown, Jeffery, Morris, Michael and Cramer, Rainer (2017) Protein identification using a nanoUHPLC-AP-MALDI MS/MS workflow with CID of multiply charged proteolytic peptides. International Journal of Mass Spectrometry, 416. pp. 20-28. ISSN 1387-3806 doi: https://doi.org/10.1016/j.ijms.2016.12.006

Castelletto, Valeria, Ryumin, Pavel, Cramer, Rainer, Hamley, I. W., Taylor, M., Allsop, D., Reza, M., Ruokolainen, J., Arnold, T., Hermida-Merino, D., Garcia, C. I., Leal, M. C. and Castaño, E. (2017) Self-assembly and anti-amyloid cytotoxicity activity of amyloid beta peptide derivatives. Scientific Reports, 7. 43637. ISSN 2045-2322 doi: https://doi.org/10.1038/srep43637

Wiangnon, Kanjana and Cramer, Rainer (2016) Liquid MALDI MS analysis of complex peptide and proteome samples. Journal of Proteome Research, 15 (9). pp. 2998-3008. ISSN 1535-3907 doi: https://doi.org/10.1021/acs.jproteome.6b00148

Ryumin, Pavel, Brown, J., Morris, M. and Cramer, Rainer (2016) Investigation and optimization of parameters affecting the multiply charged ion yield in AP-MALDI MS. Methods, 104. pp. 11-20. ISSN 1046-2023 doi: https://doi.org/10.1016/j.ymeth.2016.01.015

Timms, John F., Hale, Oliver J. and Cramer, Rainer (2016) Advances in mass spectrometry-based cancer research and analysis: from cancer proteomics to clinical diagnostics. Expert Review of Proteomics, 13 (6). pp. 593-607. ISSN 1478-9450 doi: https://doi.org/10.1080/14789450.2016.1182431

Bryant, Laura, Patole, Chhaya and Cramer, Rainer (2016) Proteomic analysis of the medicinal plant Artemisia annua: data from leaf and trichome extracts. Data In Brief, 7. pp. 325-331. ISSN 2352-3409 doi: https://doi.org/10.1016/j.dib.2016.02.038

Pennington, H. G., Gheorghe, D. M., Damerum, A., Pliego, C., Spanu, P. D., Cramer, Rainer and Bindschedler, Laurence V. (2016) Interactions between the powdery mildew effector BEC1054 and barley proteins identify candidate host targets. Journal of Proteome Research, 15 (3). pp. 826-839. ISSN 1535-3907 doi: https://doi.org/10.1021/acs.jproteome.5b00732

Bryant, L., Flatley, B., Patole, Chhaya, Brown, Geoffrey and Cramer, Rainer (2015) Proteomic analysis of Artemisia annua – towards elucidating the biosynthetic pathways of the antimalarial pro-drug artemisinin. BMC Plant Biology, 15 (1). 175. ISSN 1471-2229 doi: https://doi.org/10.1186/s12870-015-0565-7

Nouretdinov, I., Devetyarov, D., Vovk, V., Burford, B., Camuzeaux, S., Gentry-Maharaj, A., Tiss, Ali, Smith, Celia, Luo, Z., Chervonenkis, A., Hallett, R., Waterfield, M., Cramer, Rainer, Timms, J. F., Jacobs, I., Menon, U. and Gammerman, A. (2015) Multiprobabilistic prediction in early medical diagnoses. Annals of Mathematics and Artificial Intelligence, 74 (1-2). pp. 203-222. ISSN 1573-7470 doi: https://doi.org/10.1007/s10472-013-9367-5

Flatley, B., Quaye, C., Johnson, E., Freeman, A., Muneer, A., Minhas, S., Paterson, J. C., Musa, F., Malone, P. and Cramer, Rainer (2015) Distribution analysis of the putative cancer marker S100A4 across invasive squamous cell carcinoma penile tissue. EuPA Open Proteomics, 7. pp. 1-10. ISSN 2212-9685 doi: https://doi.org/10.1016/j.euprot.2015.02.001

Wiangnon, Kangana and Cramer, Rainer (2015) Sample preparation: a crucial factor for the analytical performance of rationally designed MALDI matrices. Analytical Chemistry, 87 (3). pp. 1485-1488. ISSN 0003-2700 doi: https://doi.org/10.1021/ac504412p

Flatley, B., Malone, P. and Cramer, Rainer (2014) MALDI mass spectrometry in prostate cancer biomarker discovery. Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 1844 (5). pp. 940-949. ISSN 1570-9639 doi: https://doi.org/10.1016/j.bbapap.2013.06.015

Flatley, Brian, Wilmott, Karen G., Malone, Peter and Cramer, Rainer (2014) MALDI MS profiling of post-DRE urine samples highlights the potential of b-Microseminoprotein as a marker for prostatic diseases. The Prostate, 74 (1). pp. 103-111. ISSN 1097-0045 doi: https://doi.org/10.1002/pros.22736

Cramer, Rainer, Karas, M. and Jaskolla, T.W. (2013) Enhanced MALDI MS sensitivity by weak base additives and glycerol sample coating. Analytical Chemistry, 86 (1). pp. 744-751. ISSN 0003-2700 doi: https://doi.org/10.1021/ac403228d

Agrawal, Ganesh Kumar, Sarkar, Abhijit, Righetti, Pier Giorgio, Pedreschi, Romina, Carpentier, Sebastien, Wang, Tai, Barkla, Bronwyn J., Kohli, Ajay, Ndimba, Bongani Kaiser, Bykova, Natalia V., Rampitsch, Christof, Zolla, Lello, Rafudeen, Mohamed Suhail, Cramer, Rainer, Bindschedler, Laurence, Tsakirpaloglou, Nikolaos, Job, Dominique, Kikuchi, Shoshi and Rakwal, Randeep (2013) A decade of plant proteomics and mass spectrometry: translation of technical advancements to food security and safety issues. Mass Spectrometry Reviews, 32 (5). pp. 335-365. ISSN 1098-2787 doi: https://doi.org/10.1002/mas.21365

Kovaleva, Valentina, Cramer, Rainer, Krynytskyy, Hryhoriy, Gout, Ivan and Gout, Roman (2013) Analysis of tyrosine phosphorylation and phosphotyrosine-binding proteins in germinating seeds from Scots pine. Plant Physiology and Biochemistry, 67. pp. 33-40. ISSN 0981-9428 doi: https://doi.org/10.1016/j.plaphy.2013.02.008

Cramer, Rainer, Pirkl, A., Hillenkamp, F. and Dreisewerd, K. (2013) AP-UV-MALDI mit flüssigen Matrizes: stabile Ionenausbeuten von mehrfach geladenen Peptid- und Proteinionen für die empfindliche Massenspektrometrie. Angewandte Chemie-International Edition, 125 (8). pp. 2420-2424. ISSN 1521-3773 doi: https://doi.org/10.1002/ange.201208628

Cramer, Rainer, Pirkl, Alexander, Hillenkamp, Franz and Dreisewerd, Klaus (2013) Liquid AP-UV-MALDI enables stable ion yields of multiply charged peptide and protein ions for sensitive analysis by mass spectrometry. Angewandte Chemie-International Edition, 52 (8). pp. 2364-2367. ISSN 1521-3773 doi: https://doi.org/10.1002/anie.201208628

Greenland, Barnaby W., Bird, Matthew B., Burattini, Stefano, Cramer, Rainer, O'Reilly, Rachel K., Patterson, Joseph P., Hayes, Wayne, Cardin, Christine J. and Colquhoun, Howard M. (2013) Mutual binding of polymer end-groups by complementary π–π-stacking: a molecular “Roman Handshake”. Chemical Communications, 49 (5). pp. 454-456. ISSN 1359-7345 doi: https://doi.org/10.1039/C2CC35965K

Pedersen, Carsten, van Themaat, Emiel Ver, McGuffin, Liam, Abbott, James C., Burgis, Timothy A., Barton, Geraint, Bindschedler, Laurence V., Lu, Xunli, Maekawa, Takaki, Weßling, Ralf, Cramer, Rainer, Thordal-Christensen, Hans, Panstruga, Ralph and Spanu, Pietro D. (2012) Structure and evolution of barley powdery mildew effector candidates. BMC Genomics, 13 (1). p. 694. ISSN 1471-2164 doi: https://doi.org/10.1186/1471-2164-13-694

Sarsby, J., Towers, M. W., Stain, Chris, Cramer, Rainer and Koroleva, O. A. (2012) Mass spectrometry imaging of glucosinolates in arabidopsis flowers and siliques. Phytochemistry, 77. pp. 110-118. ISSN 0031-9422 doi: https://doi.org/10.1016/j.phytochem.2012.01.026

Agrawal, G. K., Sarkar, A., Agrawal, R., Ndimba, B. K., Tanou, G., Dunn, M. J., Kieselbach, T, Cramer, Rainer, Weinkoop, S., Chen, S., Rafudeen, M. S., Deswal, R., Barkla, B. J., Weckwerth, W., Heazlewood, J. L., Renaut, J., Job, D., Chakraborty, N. and Rakwal, R. (2012) Boosting the globalization of plant proteomics through INPPO: current developments 3 and future prospects. Proteomics, 12 (3). pp. 359-368. ISSN 1615-9853 doi: https://doi.org/10.1002/pmic.201290018

Cramer, Rainer (2011) Editorial for “Advances in Biological Mass Spectrometry and Proteomics”. Methods, 54 (4). pp. 349-350. ISSN 1046-2023 doi: https://doi.org/10.1016/j.ymeth.2011.07.007

Bindschedler, Laurence V., McGuffin, Liam J., Burgis, Timothy A., Spanu, Pietro D. and Cramer, Rainer (2011) Proteogenomics and in silico structural and functional annotation of the barley powdery mildew Blumeria graminis f. sp. hordei. Methods, 54 (4). pp. 432-441. ISSN 1046-2023 doi: https://doi.org/10.1016/j.ymeth.2011.03.006

Koroleva, Olga A. and Cramer, Rainer (2011) Single-cell proteomic analysis of glucosinolate-rich S-cells in Arabidopsis thaliana. Methods, 54 (4). pp. 413-423. ISSN 1046-2023 doi: https://doi.org/10.1016/j.ymeth.2011.06.005

Bindschedler, Laurence V. and Cramer, Rainer (2011) Fully automated software solution for protein quantitation by global metabolic labeling with stable isotopes. Rapid Communications in Mass Spectrometry, 25 (11). pp. 1461-1471. ISSN 1097-0231 doi: https://doi.org/10.1002/rcm.4872

Stringano, Elisabetta, Cramer, Rainer, Hayes, Wayne, Smith, Celia, Gibson, Trevor and Mueller-Harvey, Irene (2011) Deciphering the complexity of sainfoin (Onobrychis viciifolia) proanthocyanidins by MALDI-TOF mass spectrometry with a judicious choice of isotope patterns and matrixes. Analytical Chemistry, 83 (11). pp. 4147-4153. ISSN 0003-2700 doi: https://doi.org/10.1021/ac2003856

Bauer, Chris, Kleinjung, Frank, Smith, Celia J., Towers, Mark W., Tiss, Ali, Chadt, Alexandra, Dreja, Tanja, Beule, Dieter, Al-Hasani, Hadi, Reinert, Knut, Schuchhardt, Johannes and Cramer, Rainer (2011) Biomarker discovery and redundancy reduction towards classification using a multi-factorial MALDI-TOF MS T2DM mouse model dataset. BMC Bioinformatics, 12. 140. ISSN 1471-2105 doi: https://doi.org/10.1186/1471-2105-12-140

Bindschedler, Laurence V and Cramer, Rainer (2011) Quantitative plant proteomics. PROTEOMICS, 11 (4). pp. 756-775. ISSN 1615-9861 doi: https://doi.org/10.1002/pmic.201000426

Timms, John F., Menon, Usha, Devetyarov, Dmitry, Tiss, Ali, Camuzeaux, Stephane, McCurrie, Katherine, Nouretdinov, Ilia, Burford, Brian, Smith, Celia, Gentry-Maharaj, Aleksandra, Hallett, Rachel, Ford, Jeremy, Luo, Zhiyuan, Vovk, Volodya, Gammerman, Alex, Cramer, Rainer and Jacobs, Ian (2011) Early detection of ovarian cancer in samples pre-diagnosis using CA125 and MALDI-MS peaks. Cancer Genomics and Proteomics, 8 (6). pp. 289-305. ISSN 1790-6245

Spanu, Pietro D., Abbott, James C., Amselem, Joelle, Burgis, Timothy A., Soanes, Darren M., Stuber, Kurt, Loren van Themaat, Emiel Ver, Brown, James K.M., Butcher, Sarah A., Gurr, Sarah J., Lebrun, Marc-Henri, Ridout, Christopher J., Schulze-Lefert, Paul, Talbot, Nicholas J., Ahmadinejad, Nahal, Ametz, Christian, Barton, Geraint R., Benjdia, Mariam, Bidzinski, Przemyslaw, Bindschedler, Laurence Veronique, Both, Maike, Brewer, Marin T., Cadle-Davidson, Lance, Cadle-Davidson, Molly M., Collemare, Jerome, Cramer, Rainer Karl, Frenkel, Omer, Godfrey, Dale, Harriman, James, Hoede, Claire, King, Brian C., Klages, Sven, Kleemann, Jochen, Knoll, Daniela, Koti, Prasanna S., Kreplak, Jonathan, Lopez-Ruiz, Francisco J., Lu, Xunli, Maekawa, Takaki, Mahanil, Siraprapa, Micali, Cristina, Milgroom, Michael G., Montana, Giovanni, Noir, Sandra, O'Connell, Richard J., Oberhaensli, Simone, Parlange, Francis, Pedersen, Carsten, Quesneville, Hadi, Reinhardt, Richard, Rott, Matthias, Sacristan, Soledad, Schmidt, Sarah M., Schon, Moritz, Skamnioti, Pari, Sommer, Hans, Stephens, Amber, Takahara, Hiroyuki, Thordal-Christensen, Hans, Vigouroux, Marielle, Wessling, Ralf, Wicker, Thomas and Panstruga, Ralph (2010) Genome expansion and gene loss in powdery mildew fungi reveal tradeoffs in extreme parasitism. Science, 330 (6010). pp. 1543-1546. ISSN 1095-9203 doi: https://doi.org/10.1126/science.1194573

Tiss, Ali, Timms, John F., Smith, Celia Jennifer, Devetyarov, Dmitry, Gentry-Maharaj, Aleksandra, Camuzeaux, Stephane, Burford, Brian, Nouretdinov, Iilia, Ford, Jeremy, Luo, Zhiyuan, Jacobs, Ian, Menon, Usha, Gammerman, Alex and Cramer, Rainer Karl (2010) Highly accurate detection of ovarian cancer using CA125 but limited improvement with serum matrix-assisted laser desorption/ionization time-of-flight mass spectrometry profiling. International Journal of Gynecological Cancer, 20 (9). pp. 1518-1524. ISSN 1048-891x doi: https://doi.org/10.1111/IGC.0b013e3181fc1990

Koroleva, Olga A., Gibson, Trevor M., Cramer, Rainer and Stain, Chris (2010) Glucosinolate-accumulating S-cells in Arabidopsis leaves and flower stalks undergo programmed cell death at early stages of differentiation. The Plant Journal, 64 (3). pp. 456-469. ISSN 0960-7412 doi: https://doi.org/10.1111/j.1365-313X.2010.04339.x

Flatley, Brian, Malone, Peter and Cramer, Rainer Karl (2010) MS-based clinical proteomics: biomarker discovery in men’s cancer. European Pharmaceutical Review (5). pp. 53-56. ISSN 1360-8606

Tiss, Ali, Smith, C., Menon, U, Jacobs, I, Timms, J F and Cramer, Rainer (2010) A well-characterised peak identification list of MALDI MS profile peaks for human blood serum. Proteomics, 10 (18). pp. 3388-3392. ISSN 1615-9853 doi: https://doi.org/10.1002/pmic.201000100

Stringano, Elisabetta, Hayot, C., Smith, L., Theodoridou, K., Aufrere, J., Brown, Ronald, Hayes, Wayne, Cramer, Rainer and Mueller-Harvey, Irene (2010) Thiolytic screening method for exploring condensed tannin variation in a unique sainfoin germplasm bank. Planta Medica, 76 (12). 0_3. ISSN 1439-0221 doi: https://doi.org/10.1055/s-0030-1264189

Fenton, Tim R, Gwalter, Jodie, Cramer, Rainer and Gout, Ivan T (2010) S6K1 is acetylated at lysine 516 in response to growth factor stimulation. Biochemical and biophysical research communications, 398 (3). pp. 400-405. ISSN 1090-2104 doi: https://doi.org/10.1016/j.bbrc.2010.06.081

Timms, John F, Cramer, Rainer , Camuzeaux, Stephane, Tiss, Ali, Smith, Celia, Burford, Brian, Nouretdinov, Ilia, Devetyarov, Dmitry, Gentry-Maharaj, Aleksandra, Ford, Jeremy, Luo, Zhiyuan, Gammerman, Alex, Menon, Usha and Jacobs, Ian (2010) Peptides generated ex vivo from serum proteins by tumor-specific exopeptidases are not useful biomarkers in ovarian cancer. Clinical Chemistry, 56 (2). pp. 262-271. ISSN 1530-8561 doi: https://doi.org/10.1373/clinchem.2009.133363

Towers, Mark W., McKendrick, John E. and Cramer, Rainer (2010) Introduction of 4-chloro-alpha-cyanocinnamic acid liquid matrices for high sensitivity UV-MALDI MS. Journal of Proteome Research, 9 (4). pp. 1931-1940. ISSN 1535-3893 doi: https://doi.org/10.1021/pr901089j

Bindschedler, L. V., Burgis, T. A., Mills, D. J. S., Ho, J. T. C., Cramer, R. and Spanu, P. D. (2009) In planta proteomics and proteogenomics of the biotrophic barley fungal pathogen blumeria graminis f. sp hordei. Molecular & Cellular Proteomics, 8 (10). pp. 2368-2381. ISSN 1535-9476 doi: https://doi.org/10.1074/mcp.M900188-MCP200

Palmblad, M., Tiss, A. and Cramer, R. (2009) Mass spectrometry in clinical proteomics - from the present to the future. Proteomics Clinical Applications, 3 (1). pp. 6-17. ISSN 1862-8346 doi: https://doi.org/10.1002/prca.200800090

Ortiz-Chao, P., Gomez-Ruiz, J.A., Rastall, R.A., Mills, Davinia, Cramer, R., Pihlanto, A., Korhonen, H. and Jauregi, P. (2009) Production of novel ACE inhibitory peptides from beta-lactoglobulin using Protease N Amano. International Dairy Journal, 19 (2). pp. 69-76. ISSN 0958-6946 doi: https://doi.org/10.1016/j.idairyj.2008.07.011

Kovaleva, V., Kiyamova, R., Cramer, R., Krynytskyy, H., Gout, I., Filonenko, V. and Gout, R. (2009) Purification and molecular cloning of antimicrobial peptides from Scots pine seedlings. Peptides, 30 (12). pp. 2136-2143. ISSN 0196-9781 doi: https://doi.org/10.1016/j.peptides.2009.08.007

Gammerman, A., Vovk, V., Burford, B., Nouretdinov, I., Luo, Z.Y., Chervonenkis, A., Waterfield, M., Cramer, R., Tempst, P., Villanueva, J., Kabir, M., Camuzeaux, S., Timms, J., Menon, U. and Jacobs, I. (2009) Serum proteomic abnormality predating screen detection of ovarian cancer. Computer Journal, 52 (3). pp. 326-333. ISSN 0010-4620 doi: https://doi.org/10.1093/comjnl/bxn021

Timms, J.F. and Cramer, R. (2008) Difference gel electrophoresis. Proteomics, 8 (23-24). pp. 4886-4897. ISSN 1615-9853 doi: https://doi.org/10.1002/pmic.200800298

Bindschedler, L.V., Palmblad, M. and Cramer, R. (2008) Hydroponic isotope labelling of entire plants (HILEP) for quantitative plant proteomics; an oxidative stress case study. Phytochemistry, 69 (10). pp. 1962-1972. ISSN 0031-9422 doi: https://doi.org/10.1016/j.phytochem.2008.04.007

Huang, H.L., Cendan, C.M., Roza, C., Okuse, K., Cramer, R., Timms, J.F. and Wood, J.N. (2008) Proteomic profiling of neuromas reveals alterations in protein composition and local protein synthesis in hyper-excitable nerves. Molecular Pain, 4. p. 33. ISSN 1744-8069 doi: https://doi.org/10.1186/1744-8069-4-33

Palmblad, M., Mills, Davinia J, Bindschedler, L.V. and Cramer, R. (2007) Chromatographic alignment of LC-MS and LC-MS/MS datasets by genetic algorithm feature extraction. Journal of the American Society for Mass Spectrometry, 18 (10). pp. 1835-1843. ISSN 1044-0305 doi: https://doi.org/10.1016/j.jasms.2007.07.018

Towers, M. and Cramer, R. (2007) Liquid matrices for analyses by UV-MALDI mass spectrometry. Spectroscopy, 22 (11). 29-. ISSN 0887-6703

Palmblad, M. and Cramer, Rainer (2007) Liquid matrix deposition on conductive hydrophobic surfaces for tuning and quantitation in UV-MALDI mass spectrometry. Journal of the American Society of Mass Spectrometry, 18 (4). pp. 693-697. ISSN 1044-0305 doi: https://doi.org/10.1016/j.jasms.2006.11.013

Palmblad, M., Bindschedler, L.V. and Cramer, R. (2007) Quantitative proteomics using uniform N-15-labeling, MASCOT, and the trans-proteomic pipeline. Proteomics, 7 (19). pp. 3462-3469. ISSN 1615-9853 doi: https://doi.org/10.1002/pmic.200700180

Tiss, Ali, Smith, Celia, Camuzeaux, S., Kabir, M., Gayther, S., Menon, U., Waterfield, M., Timms, J,, Jacobs, I. and Cramer, Rainer (2007) Serum peptide profiling using MALDI mass spectrometry. Proteomics, 7 (S1). pp. 77-89. ISSN 1615-9853 doi: https://doi.org/10.1002/pmic.200700746

Palmblad, M., Bindschedler, L.V., Gibson, Trevor M and Cramer, R. (2006) Automatic internal calibration in liquid chromatography/Fourier transform ion cyclotron resonance mass spectrometry of protein digests. Rapid Communications in Mass Spectrometry, 20 (20). pp. 3076-3080. ISSN 0951-4198 doi: https://doi.org/10.1002/rcm.2707

Bindschedler, Laurence Veronique, Palmblad, M. and Cramer, Rainer Karl (2006) First-dimension separation with the MicroRotoforTM cell prior to SDS-PAGE and LC-MS/MS analysis. Bio-Rad Bulletin, 5451. pp. 1-4.

Nagano, K., Bornhauser, B.C., Warnasuriya, G., Entwistle, A., Cramer, R., Lindholm, D. and Naaby-Hansen, S. (2006) PDGF regulates the actin cytoskeleton through hnRNP-K-mediated activation of the ubiquitin E-3-ligase MIR. EMBO Journal, 25 (9). pp. 1871-1882. ISSN 0261-4189 doi: https://doi.org/10.1038/sj.emboj.7601059

Jacob, R.J. and Cramer, R. (2006) PIGOK: linking protein identity to gene ontology and function. Journal of Proteome Research, 5 (12). pp. 3429-3432. ISSN 1535-3893 doi: https://doi.org/10.1021/pr0601537

Hastie, C., Saxton, M., Akpan, A., Cramer, R., Masters, J.R. and Naaby-Hans, S. (2005) Combined affinity labelling and mass spectrometry analysis of differential cell surface protein expression in normal and prostate cancer cells. Oncogene, 24 (38). pp. 5905-5913. ISSN 0950-9232 doi: https://doi.org/10.1038/sj.onc.1208747

Barnouin, K.N., Hart, S.R., Thompson, A.J., Okuyama, M., Waterfield, M. and Cramer, R. (2005) Enhanced phosphopeptide isolation by Fe(III)-IMAC using 1,1,1,3,3,3-hexafluoroisopropanol. Proteomics, 5 (17). pp. 4376-4388. ISSN 1615-9853 doi: https://doi.org/10.1002/pmic.200401323

de Graauw, M., Tijdens, I., Cramer, R., Corless, S., Timms, J.F. and van de Water, B. (2005) Heat shock protein 27 is the major differentially phosphorylated protein involved in renal epithelial cellular stress response and controls focal adhesion organization and apoptosis. The Journal of Biological Chemistry, 280 (33). pp. 29885-29898. ISSN 1083-351X doi: https://doi.org/10.1074/jbc.M412708200

Cramer, R., Gobom, J. and Nordhoff, E. (2005) High-throughput proteomics using matrix-assisted laser desorption/ionization mass spectrometry. Expert Review of Proteomics, 2 (3). pp. 407-420. ISSN 1478-9450 doi: https://doi.org/10.1586/14789450.2.3.407

Cramer, R. and Corless, S. (2005) Liquid ultraviolet matrix-assisted laser desorption/ionization mass spectrometry for automated proteomic analysis. Proteomics, 5 (2). pp. 360-370. ISSN 1615-9853 doi: https://doi.org/10.1002/pmic.200400956

Cutillas, P.R., Biber, J., Marks, J., Jacob, R., Stieger, B., Cramer, R., Waterfield, M., Burlingame, A.L. and Unwin, R.J. (2005) Proteomic analysis of plasma membrane vesicles isolated from the rat renal cortex. Proteomics, 5 (1). pp. 101-112. ISSN 1615-9853

Chan, H.L., Gharbi, S., Gaffney, P.R., Cramer, R. , Waterfield, M.D. and Timms, J.F. (2005) Proteomic analysis of redox- and ErbB2-dependent changes in mammary luminal epithelial cells using cysteine- and lysine-labelling two-dimensional difference gel electrophoresis. Proteomics, 5 (11). pp. 2908-2926. ISSN 1615-9853 doi: https://doi.org/10.1002/pmic.200401300

Weeks, M.E., Sinclair, J., Jacob, R.J., Saxton, M.J., Kirby, S., Jones, J., Waterfield, M.D., Cramer, R. and Timms, J.F. (2005) Stress-induced changes in the Schizosaccharomyces pombe proteome using two-dimensional difference gel electrophoresis, mass spectrometry and a novel integrated robotics platform. Proteomics, 5 (6). pp. 1669-1685. ISSN 1615-9853 doi: https://doi.org/10.1002/pmic.200401241

Book or Report Section

Piras, Cristian and Cramer, Rainer ORCID: https://orcid.org/0000-0002-8037-2511 (2023) Liquid Atmospheric Pressure (LAP) - MALDI MS(/MS) biomolecular profiling for large-scale detection of animal disease and food adulteration and bacterial identification. In: Shah, Haroun N., Gharbia, Saheer E., Shah, Ajit, Tranfield, Erika and Thompson, Clive (eds.) Microbiological Identification using MALDI-TOF and Tandem Mass Spectrometry: Industrial and Environmental Applications. Wiley. ISBN 9781119814054 (In Press)

Wiangnon, Kanjana and Cramer, Rainer (2016) Coupling liquid MALDI MS to liquid chromatography. In: Cramer, Rainer (ed.) Advances in MALDI and Laser-Induced Soft Ionization Mass Spectrometry. Springer, pp. 65-76. ISBN 9783319048185 doi: https://doi.org/10.1007/978-3-319-04819-2_4

Ryumin, Pavel and Cramer, Rainer (2016) Efficient production of multiply charged MALDI ions. In: Cramer, Rainer (ed.) Advances in MALDI and Laser-Induced Soft Ionization Mass Spectrometry. Springer, pp. 37-47. ISBN 9783319048185 doi: https://doi.org/10.1007/978-3-319-04819-2_2

Towers, Mark W. and Cramer, Rainer (2016) Ionic liquids and other liquid matrices for sensitive MALDI MS analysis. In: Cramer, Rainer (ed.) Advances in MALDI and Laser-Induced Soft Ionization Mass Spectrometry. Springer, pp. 51-64. ISBN 9783319048185 doi: https://doi.org/10.1007/978-3-319-04819-2_3

Cramer, Rainer (2016) Preface. In: Cramer, Rainer (ed.) Advances in MALDI and Laser-Induced Soft Ionization Mass Spectrometry. Springer. ISBN 9783319048185

Smith, Celia, Mills, Davinia and Cramer, Rainer (2012) Application of DIGE and mass spectrometry in the study of type 2 Diabetes Mellitus (T2DM) mouse models. In: Cramer, Rainer and Westermeier, Reiner (eds.) Difference Gel Electrophoresis (DIGE). Methods in molecular biology (854). Humana Press / Springer, New York, pp. 299-318. ISBN 9781617795725 doi: https://doi.org/10.1007/978-1-61779-573-2_21

Bindschedler, Laurence Veronique, Smith, Calvin James and Cramer, Rainer Karl (2011) Quantitative plant proteomics using hydroponic isotope labeling of entire plants (HILEP). In: Ivanov, Alexander R. and Lazarev, Alexander V. (eds.) Sample preparation in biological mass spectrometry. Springer, New York. ISBN 9789400707580

Bauer, C., Cramer, Rainer and Schuchhardt, J. (2011) Evaluation of peak-picking algorithms for protein mass spectrometry. In: Hamacher, M., Eisenacher, M. and Stephan, C. (eds.) Data mining in proteomics: from standards to applications. Methods in molecular biology, 696. Humana Press, USA, pp. 341-352. ISBN 9781607619864 doi: https://doi.org/10.1007/978-1-60761-987-1_22

Tiss, Ali, Smith, Celia Jennifer and Cramer, Rainer (2011) MALDI MS-based biomarker profiling of blood samples. In: Ivanov, Alexander R. and Lazarev, Alexander V. (eds.) Sample preparation in biological mass spectrometry. Springer, New York, pp. 733-747. ISBN 9789400707580

Cramer, R. (2009) MALDI MS. In: Reinders, J. and Sickmann, A. (eds.) Proteomics: methods and protocols. Methods in molecular biology, 564. Humana Press, Totowa, New Jersey, pp. 85-103. ISBN 9781607611561 doi: https://doi.org/10.1007/978-1-60761-157-8_5

Cramer, Rainer and Dreisewerd, K (2007) UV matrix-assisted laser desorption ionization: principles instrumentation and applications. In: Gross, M L and Capriolo, R M (eds.) The encyclopedia of mass spectrometry. Elsevier. ISBN 9780080438016

Naaby-Hansen, S., Warnasuriya, G.D., Hastie, C., Gallney, P. and Cramer, R. (2005) Proteomic approaches in the analysis of hypertension. In: Fennell, J.P. and Baker, A.H. (eds.) Hypertension: methods and protocols. Methods in molecular medicine, 108. Humana Press, New Jersey, pp. 275-296. ISBN 9781588293237

Conference or Workshop Item

Hale, Oliver J., Morris, Mike and Cramer, Rainer (2017) AP-MALDI-Q-IMS-TOF MS as a liquid sample mass profiling platform for food authenticity tests. In: 65th ASMS Conference on Mass Spectrometry, June 4 – 8, 2017, Indianapolis, IN, USA.

Brown, Jeff, Morris, Michael and Cramer, Rainer (2017) Liquid AP-MALDI: ion signal intensity and persistence at laser repetition rates between 1 Hz and 5 kHz. In: 65th ASMS Conference on Mass Spectrometry, June 4 – 8, 2017, Indianapolis, IN, USA.

Stringano, Elisabetta, Gea, A., Cramer, Rainer , Hayes, Wayne and Mueller-Harvey, Irene (2010) Structural diversity of sainfoin (Onobrychis viciifolia) tannins. In: 25th International Conference on Polyphenols, 24th - 27th August 2010, Montpellier, France.

Bindschedler, Laurence Veronique, Towers, M and Cramer, Rainer Karl (2009) Hydroponic isotope labeling of entire plants (HILEP) for quantitative plant proteomics. In: 55th ASMS Conference on Mass Spectrometry, 3rd - 7th June 2007, Indianapolis, USA.

Bindschedler, Laurence Veronique, Burgis, T, Mills, Davinia Joanne Susan, Ho, J, Spanu, P D and Cramer, Rainer K (2009) In planta proteomics and proteogenomics of the biotrophic barley fungal pathogen blumeria f.sp. hordei. In: 57th ASMS Conference on Mass Spectrometry, 31st May - 4th June 2009, Philadelphia, Pennsylvania, USA.

Towers, M.W., McKendrick, John Ennis and Cramer, R. (2009) High Sensitivity α-cyano-4-Chlorocinnamic Acid Liquid Matrices for UV-MALDI MS. In: Proceedings of the 57th ASMS Conference on Mass Spectrometry, Philadelphia, PA, USA.

Towers, M.W., Rollin, K., Tiss, A. and Cramer, R. (2009) Is liquid UV-MALDI a real alternative to solid state UV-MALDI? In: 57th ASMS Conference on Mass Spectrometry, Philadelphia, Pennsylvania, USA.

Tiss, A., Smith, C., Menon, U., Jacobs, I., Timms, J.F. and Cramer, R. (2009) An extensive peptide identification list of MALDI MS profile peaks from the analysis of human blood serum. In: 57th ASMS Conference on Mass Spectrometry, Philadelphia, Pennsylvania, USA.

Bindschedler, L.V. and Cramer, R. (2008) Equalisation of protein amounts for overcoming the high dynamic protein expression range in the analysis of plant proteomes. In: 56th ASMS Conference on Mass Spectrometry, Denver, Colorado, USA, MP 573.

Towers, M. and Cramer, R. (2008) High-sensitivity liquid UV-MALDI-MS analysis. In: 56th ASMS Conference on Mass Spectrometry, Denver, Colorado, USA, TP 047.

Tiss, A., Smith, C., Timms, J., Luo, A., Gammerman, A., Waterfield, M., Menon, U., Jacobs, I. and Cramer, R. (2008) A robust and sensitive automated method for MS-based serum pattern diagnostics using well-established ZipTip technology and ultrafiltration. In: 56th ASMS Conference on Mass Spectrometry, Denver, Colorado, USA, MP 624.

Palmbland, M., Towers, M. and Cramer, Rainer (2007) Investigation of liquid MALDI and optimization for instrument tuning and quantitative measurements. In: 55th ASMS Conference on Mass Spectrometry, 3- 7 June 2007, Indianapolis, USA.

Palmblad, M., Towers, M. and Cramer, Rainer (2007) Multiplexed quantitative proteomics using differential metabolic 15N-labeling. In: 55th ASMS Conference on Mass Spectrometry, 3-7 June 2007, Indianapolis, USA.

Palmblad, M., Bindschedler, Laurence Veronique, Gibson, Trevor Michael and Cramer, Rainer Karl (2006) Comparison of bottom-up protein identification methods. In: 54th ASMS Conference on Mass Spectrometry, 28th May - 1st June 2006, Seattle USA.

Jacob, R. J., Thompson, A. and Cramer, R. (2005) A preliminary comparative analysis of the H. sapiens saliva proteome between cysteine fractionation,performic acid oxidation LC/MALDI/MS/MS and LC/ESI/MS/MS. In: 53rd ASMS conference on mass spectrometry and allied topics, 5-9 Jun 2005, San Antonio, TX. (Unpublished)

Book

Cramer, Rainer, ed. (2016) Advances in MALDI and laser-induced soft ionization mass spectrometry. Springer. ISBN 9783319048185

Cramer, Rainer and Westermeier, Reiner, eds. (2012) Difference Gel Electrophoresis (DIGE). Humana Press. ISBN 9781617795725 doi: https://doi.org/10.1007/978-1-61779-573-2