Number of items: 27.
Article
Khater, M., Brazier, J. ORCID: https://orcid.org/0000-0002-4952-584X, Greco, F. and Osborn, H. ORCID: https://orcid.org/0000-0002-0683-0457
(2023)
Anticancer evaluation of new organometallic ruthenium(II) flavone complexes.
Medicinal Chemistry, 14 (2).
pp. 253-267.
ISSN 2632-8682
doi: https://doi.org/10.1039/D2MD00304J
Hutchins, M., Bovill, R. A., Stephens, P. J., Brazier, J. A. ORCID: https://orcid.org/0000-0002-4952-584X and Osborn, H. M. I. ORCID: https://orcid.org/0000-0002-0683-0457
(2022)
Glycosides of nadifloxacin—synthesis and antibacterial
activities against methicillin-resistant Staphylococcus aureus.
Molecules, 27 (5).
1504.
ISSN 1420-3049
doi: https://doi.org/10.3390/molecules27051504
Baptista, F. R., Devereux, S. J., Gurung, S. P., Hall, J. P. ORCID: https://orcid.org/0000-0003-3716-4378, Sazanovich, I. V., Towrie, M., Cardin, C. J. ORCID: https://orcid.org/0000-0002-2556-9995, Brazier, J. A. ORCID: https://orcid.org/0000-0002-4952-584X, Kelly, J. M. and Quinn, S. J.
(2020)
The influence of loops on the binding of the [Ru(phen)2dppz]2+ light-switch compound to i-motif DNA structures revealed by time-resolved spectroscopy.
Chemical Communications, 56 (67).
pp. 9703-9706.
ISSN 1359-7345
doi: https://doi.org/10.1039/D0CC03702H
Pages, B. J., Gurung, S. P., McQuaid, K. ORCID: https://orcid.org/0000-0002-3222-5584, Hall, J. P. ORCID: https://orcid.org/0000-0003-3716-4378, Cardin, C. J. ORCID: https://orcid.org/0000-0002-2556-9995 and Brazier, J. A. ORCID: https://orcid.org/0000-0002-4952-584X
(2019)
Stabilization of long-looped i-motif DNA by polypyridyl ruthenium complexes.
Frontiers in Chemistry, 7.
744.
ISSN 2296-2646
doi: https://doi.org/10.3389/fchem.2019.00744
McQuaid, K., Abell, H., Gurung, S. P., Allan, D. R., Winter, G., Sorensen, T., Cardin, D. J., Brazier, J. A. ORCID: https://orcid.org/0000-0002-4952-584X, Cardin, C. J. ORCID: https://orcid.org/0000-0002-2556-9995 and Hall, J. P. ORCID: https://orcid.org/0000-0003-3716-4378
(2019)
Structural studies reveal the enantiospecific recognition of a DNA G-quadruplex by a ruthenium polypyridyl complex.
Angewandte Chemie International Edition, 58 (29).
pp. 9881-9885.
ISSN 1433-7851
doi: https://doi.org/10.1002/anie.201814502
McQuaid, K., Hall, J. P. ORCID: https://orcid.org/0000-0003-3716-4378, Brazier, J. A. ORCID: https://orcid.org/0000-0002-4952-584X, Cardin, D. J. and Cardin, C. J. ORCID: https://orcid.org/0000-0002-2556-9995
(2018)
X-ray crystal structures show DNA stacking advantage of terminal nitrile substitution in Ru-dppz complexes.
Chemistry- A European Journal, 24 (59).
pp. 15859-15867.
ISSN 1521-3765
doi: https://doi.org/10.1002/chem.201803021
Takahashi, S., Brazier, J. A. ORCID: https://orcid.org/0000-0002-4952-584X and Sugimoto, N.
(2017)
Topological impact of noncanonical DNA structures on Klenow fragment of DNA polymerase.
Proceedings of the National Academy of Sciences of the United States of America, 114 (36).
pp. 9605-9610.
ISSN 0027-8424
doi: https://doi.org/10.1073/pnas.1704258114
Hall, J. P. ORCID: https://orcid.org/0000-0003-3716-4378, Gurung, S. P., Henle, J., Poidl, P., Andersson, J., Lincoln, P., Winter, G., Sorensen, T., Cardin, D. J., Brazier, J. A. ORCID: https://orcid.org/0000-0002-4952-584X and Cardin, C. J. ORCID: https://orcid.org/0000-0002-2556-9995
(2017)
Guanine can direct binding specificity of Ru-dppz complexes to DNA through steric effects.
Chemistry: A European Journal, 23 (21).
pp. 4981-4985.
ISSN 0947-6539
doi: https://doi.org/10.1002/chem.201605508
Hall, J. P. ORCID: https://orcid.org/0000-0003-3716-4378, Keane, P. M., Beer, H., Buchner, K., Winter, G., Sorensen, T. L., Cardin, D. J., Brazier, J. A. ORCID: https://orcid.org/0000-0002-4952-584X and Cardin, C. J. ORCID: https://orcid.org/0000-0002-2556-9995
(2016)
Delta chirality ruthenium ‘light-switch’ complexes can bind in the minor groove of DNA with five different binding modes.
Nucleic Acids Research, 44 (19).
pp. 9472-9482.
ISSN 1362-4962
doi: https://doi.org/10.1093/nar/gkw753
Keane, P. M., Baptista, F. R., Gurung, S. P., Devereux, S. J., Sazanovich, I. V., Towrie, M., Brazier, J. A. ORCID: https://orcid.org/0000-0002-4952-584X, Cardin, C. J. ORCID: https://orcid.org/0000-0002-2556-9995, Kelly, J. M. and Quinn, S. J.
(2016)
Long-lived excited-state dynamics of i-motif structures probed by time-resolved infrared spectroscopy.
ChemPhysChem, 17 (9).
pp. 1281-1287.
ISSN 1439-7641
doi: https://doi.org/10.1002/cphc.201501183
Parshotam, J. P., Brazier, J. A. ORCID: https://orcid.org/0000-0002-4952-584X, Bovill, R. and Osborn, H. M. I. ORCID: https://orcid.org/0000-0002-0683-0457
(2016)
An efficient and rapid microwave-assisted synthesis of 1-acetyl-1H-indol-3-YL acetates.
Current Microwave Chemistry, 3 (3).
pp. 247-257.
ISSN 2213-3364
doi: https://doi.org/10.2174/2213335603666160108001556
Hall, J. P. ORCID: https://orcid.org/0000-0003-3716-4378, Poynton, F. E., Keane, P. M., Gurung, S. P., Brazier, J. A. ORCID: https://orcid.org/0000-0002-4952-584X, Cardin, D. J., Winter, G., Gunnlaugsson, T., Sazanovich, I. V., Towrie, M., Cardin, C. J. ORCID: https://orcid.org/0000-0002-2556-9995, Kelly, J. M. and Quinn, S. J.
(2015)
Monitoring one-electron photo-oxidation of guanine in DNA crystals using ultrafast infrared spectroscopy.
Nature Chemistry, 7.
pp. 961-967.
ISSN 1755-4330
doi: https://doi.org/10.1038/nchem.2369
Olorunniji, F. J., McPherson, A. L., Pavlou, H. J., McIlwraith, M. J., Brazier, J. ORCID: https://orcid.org/0000-0002-4952-584X, Cosstick, R. and Stark, W. M.
(2015)
Nicked-site substrates for a serine recombinase reveal enzyme–DNA communications and an essential tethering role of covalent enzyme–DNA linkages.
Nucleic Acids Research, 43 (12).
pp. 6134-6143.
ISSN 1362-4962
doi: https://doi.org/10.1093/nar/gkv521
Kikuta, K., Piao, H., Brazier, J. ORCID: https://orcid.org/0000-0002-4952-584X, Taniguchi, Y., Onizuka, K., Nagatsugi, F. and Sasaki, S.
(2015)
Stabilization of the i-motif structure by the intra-strand cross-link formation.
Bioorganic & Medicinal Chemistry Letters, 25 (16).
pp. 3307-3310.
ISSN 0960-894X
doi: https://doi.org/10.1016/j.bmcl.2015.05.064
Gurung, S. P., Schwarz, C., Hall, J. P. ORCID: https://orcid.org/0000-0003-3716-4378, Cardin, C. J. ORCID: https://orcid.org/0000-0002-2556-9995 and Brazier, J. A. ORCID: https://orcid.org/0000-0002-4952-584X
(2015)
The importance of loop length on the stability of i-motif structures.
Chemical Communications, 51 (26).
pp. 5630-5632.
ISSN 1359-7345
doi: https://doi.org/10.1039/C4CC07279K
Hall, J. P. ORCID: https://orcid.org/0000-0003-3716-4378, Sanchez-Weatherby, J., Alberti, C., Hurtado Quimper, C., O'Sullivan, K., Brazier, J. A. ORCID: https://orcid.org/0000-0002-4952-584X, Winter, G., Sorensen, T., Kelly, J. M., Cardin, D. J. and Cardin, C. J. ORCID: https://orcid.org/0000-0002-2556-9995
(2014)
Controlled dehydration of a ruthenium complex-DNA crystal induces reversible DNA kinking.
Journal of the American Chemical Society, 136 (50).
pp. 17505-17512.
ISSN 0002-7863
doi: https://doi.org/10.1021/ja508745x
Hall, J. P., Cook, D., Morte, S. R., McIntyre, P., Buchner, K., Beer, H., Cardin, D., Brazier, J. ORCID: https://orcid.org/0000-0002-4952-584X, Winter, G., Kelly, J. M. and Cardin, C. ORCID: https://orcid.org/0000-0002-2556-9995
(2013)
X‑ray crystal structure of rac-[Ru(phen)2dppz]2+ with d(ATGCAT)2 shows enantiomer orientations and water ordering.
Journal of the American Chemical Society, 135 (34).
pp. 12652-12659.
ISSN 0002-7863
doi: https://doi.org/10.1021/ja403590e
Brazier, J. A. ORCID: https://orcid.org/0000-0002-4952-584X, Shah, A. and Brown, G. D.
(2012)
I-Motif formation in gene promoters: unusually stable formation in sequences complementary to known G-quadruplexes.
Chemical Communication, 48 (87).
pp. 10739-10741.
ISSN 1359-7345
doi: https://doi.org/10.1039/C2CC30863K
Jayakumar, H.K., Buckingham, J., Brazier, J. A. ORCID: https://orcid.org/0000-0002-4952-584X, Berry, N.G., Cosstick, R. and Fisher, J.
(2007)
NMR studies of the conformational effect of single and double 3'-S-phosphorothiolate substitutions within deoxythymidine trinucleotides.
Magnetic Resonance in Chemistry, 45 (4).
pp. 340-345.
ISSN 1097-458X
doi: https://doi.org/10.1002/mrc.1977
Bentley, J., Brazier, J. ORCID: https://orcid.org/0000-0002-4952-584X, Fisher, J. and Cosstick, R.
(2007)
Duplex stability of DNA.DNA and DNA.RNA duplexes containing 3 '-S-phosphorothiolate linkages.
Organic & Biomolecular Chemistry, 5 (22).
pp. 3698-3702.
ISSN 1477-0520
doi: https://doi.org/10.1039/b713292a
Cosstick, R., Buckingham, J., Brazier, J. ORCID: https://orcid.org/0000-0002-4952-584X and Fisher, J.
(2007)
Stabilization of multi-stranded nucleic acid structures using 3'-S-phosphorothiolate linkages.
Nucleosides Nucleotides & Nucleic Acids, 26 (6-7).
pp. 555-558.
ISSN 1525-7770
doi: https://doi.org/10.1080/15257770701490001
Gaynor, J. W., Brazier, J. ORCID: https://orcid.org/0000-0002-4952-584X and Cosstick, R.
(2007)
Synthesis of 3 '-S-phosphorothiolate oligonucleotides for their potential use in RNA interference.
Nucleosides Nucleotides & Nucleic Acids, 26 (6-7).
pp. 709-712.
ISSN 1525-7770
doi: https://doi.org/10.1080/15257770701490753
Brazier, J. A. ORCID: https://orcid.org/0000-0002-4952-584X, Fisher, J. and Cosstick, R.
(2006)
Stabilization of the DNA I-motif structure by incorporation of 3 '-S-phosphorothiolate linkages.
Angewandte Chemie-International Edition, 45 (1).
pp. 114-117.
ISSN 1521-3773
doi: https://doi.org/10.1002/anie.200503110
Shibata, T., Buurma, N. J., Brazier, J. A. ORCID: https://orcid.org/0000-0002-4952-584X, Thompson, P., Haq, I. and Williams, D. M.
(2006)
7,8-dihydropyrido[2,3-d]pyrimidin-2-one; a bicyclic cytosine analogue capable of enhanced stabilisation of DNA duplexes.
Chemical Communications (33).
pp. 3516-3518.
ISSN 1359-7345
doi: https://doi.org/10.1039/B606058G
Brazier, J. A. ORCID: https://orcid.org/0000-0002-4952-584X, Shibata, T., Townsley, J., Taylor, B. F., Frary, E., Williams, N. H. and Williams, D. M.
(2005)
Amino-functionalized DNA: the properties of C5-amino-alkyl substituted 2′-deoxyuridines and their application in DNA triplex formation.
Nucleic Acids Research, 33 (4).
pp. 1362-1371.
ISSN 1362-4962
doi: https://doi.org/10.1093/nar/gki254
Lee, S.E., Sidorov, A., Gourlain, T., Mignet, N., Thorpe, S.J., Brazier, J.A. ORCID: https://orcid.org/0000-0002-4952-584X, Dickman, M.J., Hornby, D.P., Grasby, J.A. and Williams, D.M.
(2001)
Enhancing the catalytic repertoire of nucleic acids: a systematic study of linker length and rigidity.
Nucleic Acids Research, 29 (7).
pp. 1565-1573.
ISSN 1362-4962
doi: https://doi.org/10.1093/nar/29.7.1565
Conference or Workshop Item
Roberts, J., Bowen, J., Brazier, J. ORCID: https://orcid.org/0000-0002-4952-584X, Lonnen, E. and Walker, G.
(2014)
Discerning the conformation of G-quadruplex forming DNA.
In: 4th EOS Topical Meeting on Terahertz Science & Technology, 2014, Camogli, Italy.
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