Article

Toman, M., Wade, J. J., Verkhratsky, A., Dallas, M. ORCID: https://orcid.org/0000-0002-5190-0522, Bithell, A., Flanagan, B., Harkin, J. and McDaid, L. (2023) The influence of astrocytic leaflet motility on ionic signalling and homeostasis at active synapses. Scientific Reports, 13 (1). 3050. ISSN 2045-2322 doi: https://doi.org/10.1038/s41598-023-30189-8

Rosa, E., de Mello, L., Castelletto, V. ORCID: https://orcid.org/0000-0002-3705-0162, Dallas, M. ORCID: https://orcid.org/0000-0002-5190-0522, Accardo, A., Seitsonen, J. and Hamley, I. W. ORCID: https://orcid.org/0000-0002-4549-0926 (2023) Cell adhesion motif-functionalized lipopeptides: nanostructure and selective myoblast cytocompatibility. Biomacromolecules, 24 (1). pp. 213-224. ISSN 1525-7797 doi: https://doi.org/10.1021/acs.biomac.2c01068

Kaisis, E., Thei, L. J., Stephens, G. J. ORCID: https://orcid.org/0000-0002-8966-4238 and Dallas, M. L. ORCID: https://orcid.org/0000-0002-5190-0522 (2022) Protofibrillar amyloid beta modulation of recombinant hCaV2.2 (N-type) voltage-gated channels. Pharmaceuticals, 15 (12). 1459. ISSN 1424-8247 doi: https://doi.org/10.3390/ph15121459

MacMillan, S., Holmes, A. P., Dallas, M. L. ORCID: https://orcid.org/0000-0002-5190-0522, Mahmoud, A. D., Shipston, M. J., Peers, C., Hardie, D. G., Kumar, P. and Evans, A. M. (2022) LKB1 is the gatekeeper of carotid body chemosensing and the hypoxic ventilatory response. Communications Biology, 5. 642. ISSN 2399-3642 doi: https://doi.org/10.1038/s42003-022-03583-7

Poshtkohi, A. ORCID: https://orcid.org/0000-0001-5636-1567, Wade, J. ORCID: https://orcid.org/0000-0003-1300-9429, McDaid, L. ORCID: https://orcid.org/0000-0002-1197-4375, Liu, J. ORCID: https://orcid.org/0000-0002-9790-1571, Dallas, M. ORCID: https://orcid.org/0000-0002-5190-0522 and Bithell, A. ORCID: https://orcid.org/0000-0002-0294-078X (2021) Mathematical modelling of human P2X-mediated plasma membrane electrophysiology and calcium dynamics in microglia. PLOS Computational Biology, 17 (11). e1009520. ISSN 1553-7358 doi: https://doi.org/10.1371/journal.pcbi.1009520

Dallas, M. L. ORCID: https://orcid.org/0000-0002-5190-0522, Al-Owais, M. M., Hettiarachchi, N. T., Vandiver, M. S., Jarosz-Griffiths, H. H., Scragg, J. L., Boyle, J. P., Dallas, D. and Peers, C. (2021) Hydrogen sulfide regulates hippocampal neuron excitability via S-sulfhydration of Kv2.1. Scientific Reports, 11. 8194. ISSN 2045-2322 doi: https://doi.org/10.1038/s41598-021-87646-5

Dallas, M. ORCID: https://orcid.org/0000-0002-5190-0522 and Widera, D. ORCID: https://orcid.org/0000-0003-1686-130X (2021) TLR2 and TLR4-mediated inflammation in Alzheimer`s disease: self-defense or sabotage? Neural Regeneration Research, 16 (8). pp. 1552-1553. ISSN 1876-7958 doi: https://doi.org/10.4103/1673-5374.303016

Rawlinson, C., Jenkins, S., Thei, L., Dallas, M. L. and Chen, R. (2020) Post-ischaemic immunological response in the brain: targeting microglia in ischaemic stroke therapy. Brain Sciences, 10 (3). 159. ISSN 2076-3425 doi: https://doi.org/10.3390/brainsci10030159

Mascal, M., Hafezi, N., Wang, D., Hu, Y., Serra, G., Dallas, M. L. ORCID: https://orcid.org/0000-0002-5190-0522 and Spencer, J. P. E. (2019) Synthetic, non-intoxicating 8,9-dihydrocannabidiol for the mitigation of seizures. Scientific Reports, 9 (1). 7778. ISSN 2045-2322 doi: https://doi.org/10.1038/s41598-019-44056-y

Wade, J. J., Breslin, K., Wong-Lin, K., Harkin, J., Flanagan, B., Van Zalinge, H., Hall, S., Dallas, M., Bithell, A., Verkhratsky, A. and McDaid, L. (2019) Calcium microdomain formation at the perisynaptic cradle due to NCX reversal: a computational study. Frontiers in Cellular Neuroscience, 13. 185. ISSN 1662-5102 doi: https://doi.org/10.3389/fncel.2019.00185

Serra, I., Scheldeman, C., Bazelot, M., Whalley, B. J., Dallas, M. L., De Witte, P. A. M. and Williams, C. M. (2019) Cannabidiol modulates phosphorylated rpS6 signalling in a zebrafish model of tuberous sclerosis complex. Behavioural Brain Research, 363. pp. 135-144. ISSN 0166-4328 doi: https://doi.org/10.1016/j.bbr.2019.01.040

De Simone, A., Naldi, M., Tedesco, D., Milelli, A., Bartolini, M., Davani, L., Widera, D., Dallas, M. and Andrisano, V. (2019) Investigating in vitro amyloid peptide 1-42 aggregation: impact of higher molecular weight stable adducts. ACS Omega, 4 (7). pp. 12308-12318. ISSN 2470-1343 doi: https://doi.org/10.1021/acsomega.9b01531

Thei, L., Imm, J., Kaisis, E., Dallas, M. L. and Dallas, T. L. (2018) Microglia in Alzheimer's disease: a role for ion channels. Frontiers in Neuroscience, 12. 676. ISSN 1662-453X doi: https://doi.org/10.3389/fnins.2018.00676

Bell, D. C. and Dallas, M. (2018) Using automated patch clamp electrophysiology platforms in pain-related ion channel research: insights from industry and academia. British Journal of Pharmacology, 175 (12). pp. 2312-2321. ISSN 1476-5381 doi: https://doi.org/10.1111/bph.13916

Hettiarachchi, N. T., Boyle, J. P., Dallas, M., Al-Owais, M. M., Scragg, J. L. and Peers, C. (2017) Heme oxygenase-1 derived carbon monoxide suppresses Aβ1-42 toxicity in astrocytes. Cell Death and Disease, 8 (6). e2884. ISSN 1350-9047 doi: https://doi.org/10.1038/cddis.2017.276

Ugbode, C., Yuhan, H., Whalley, B., Peers, C., Rattray, M. and Dallas, M. L. (2017) Astrocytic transporters in Alzheimer's disease. Biochemical Journal, 474 (3). pp. 333-355. ISSN 1470-8728 doi: https://doi.org/10.1042/BCJ20160505

Al-Owais, M. M., Hettiarachchi, N. T., Boyle, J. P., Scragg, J. L., Elies, J., Dallas, M. L., Lippiat, J., Steele, D. S. and Peers, C. (2017) Multiple mechanisms mediating carbon monoxide inhibition of the voltage-gated K+ channel Kv1.5. Cell Death and Disease, 8. e3163. ISSN 1350-9047 doi: https://doi.org/10.1038/cddis.2017.568

Hover, S., King, B., Hall, B., Loundras, E.-A., Taqi, H., Daly, J., Dallas, M., Peers, C., Schnettler, E., McKimmie, C., Kohl, A., Barr, J. N. and Mankouri, J. (2016) Modulation of potassium channels inhibits bunyavirus infection. The Journal of Biological Chemistry, 291 (7). pp. 3411-3422. ISSN 1083-351X doi: https://doi.org/10.1074/jbc.M115.692673

Ibeas Bih, C., Chen, T., Nunn, A. V. W., Bazelot, M., Dallas, M. and Whalley, B. J. (2015) Molecular targets of cannabidiol in neurological disorders. Neurotherapeutics, 12 (4). pp. 699-730. ISSN 1933-7213 doi: https://doi.org/10.1007/s13311-015-0377-3

Peers, C., Boyle, J. P., Scragg, J. L., Dallas, M., Al-Owais, M. M., Hettiarachichi, N. T., Elies, J., Johnson, E., Gamper, N. and Steele, D. (2015) Diverse mechanisms underlying the regulation of ion channels by carbon monoxide. British Journal of Pharmacology, 172 (6). pp. 1546-1556. ISSN 0007-1188 doi: https://doi.org/10.1111/bph.12760

Duckles, H., Boycott, H. E., Al-Owais, M. M., Elies, J., Johnson, E., Dallas, M. L., Porter, K. E., Giuntini, F., Boyle, J. P., Scragg, J. L. and Peers, C. (2015) Heme oxygenase-1 regulates cell proliferation via carbon monoxide-mediated inhibition of T-type Ca2+ channels. Pflugers Archive: European Journal of Physiology, 467 (2). pp. 415-427. ISSN 1432-2013 doi: https://doi.org/10.1007/s00424-014-1503-5

Karttunen, S., Duffield, M., Scrimgeour, N. R., Squires, L., Lim, W. L., Dallas, M. L., Scragg, J. L., Chicher, J., Dave, K. A., Whitelaw, M. L., Peers, C., Gorman, J. J., Gleadle, J. M., Rychkov, G. Y. and Peet, D. J. (2015) Oxygen-dependent hydroxylation by Factor Inhibiting HIF (FIH) regulates the TRPV3 ion channel. Journal of Cell Science, 128 (2). pp. 225-231. ISSN 0021-9533 doi: https://doi.org/10.1242/jcs.158451

Hettiarachchi, N. T., Dallas, M., Al-Owais, M. M., Griffiths, H. H., Hooper, N. M., Scragg, J. L., Boyle, J. P. and Peers, C. (2014) Heme oxygenase-1 protects against Alzheimer’s amyloid-β1-42 induced toxicity via carbon monoxide production. Cell Death and Disease. e1569. ISSN 1350-9047 doi: https://doi.org/10.1038/cddis.2014.529

Elies, J., Scragg, J. L., Huang, S., Dallas, M., Huang, D., MacDougall, D., Boyle, J. P., Gamper, N. and Peers, C. (2014) Hydrogen sulfide inhibits Cav3.2 T-type Ca2+ channels. FASEB Journal, 28 (12). pp. 5376-5387. ISSN 0892-6638 doi: https://doi.org/10.1096/fj.14-257113

Ronzitti, G., Bucci, G., Emanuele, M., Leo, D., Sotnikova, T. D., Mus, L. V., Soubrane, C. H., Dallas, M. L., Thalhammer, A., Cingolani, L. A., Mochida, S., Gainetdinov, R. R., Stephens, G. J. and Chieregatti, E. (2014) Exogenous alpha-Synuclein decreases raft partitioning of Cav2.2 channels inducing dopamine release. Journal of Neuroscience, 34 (32). pp. 10603-10615. ISSN 1529-2401 doi: https://doi.org/10.1523/JNEUROSCI.0608-14.2014

Peers, C., Boyle, J. P., Scragg, J. L., Dallas, M. L., Al-Owais, M. M., Hettiarachichi, N. T., Elies, J., Johnson, E., Gamper, N. and Steele, D. S. (2014) Diverse mechanisms underlying the regulation of ion channels by carbon monoxide. British Journal of Pharmacology, 172 (6). pp. 1546-1556. ISSN 0007-1188 doi: https://doi.org/10.1111/bph.12760

Elies, J., Dallas, M. L., Boyle, J. P., Scragg, J. L., Duke, A., Steele, D. S. and Peers, C. (2014) Inhibition of the cardiac Na+ channel Nav1.5 by carbon monoxide. The Journal of Biological Chemistry, 289 (23). pp. 16421-16429. ISSN 1083-351X doi: https://doi.org/10.1074/jbc.M114.569996

Amako, Y., Igloi, Z., Mankouri, J., Kazlauskas, A., Saksela, K., Dallas, M., Peers, C. and Harris, M. (2013) Hepatitis C virus NS5A inhibits mixed lineage kinase 3 to block apoptosis. The Journal of Biological Chemistry, 288 (34). pp. 24753-24763. ISSN 1083-351X doi: https://doi.org/10.1074/jbc.M113.491985

Boycott, H. E., Dallas, M., Elies, J., Pettinger, L., Boyle, J. P., Scragg, J. L., Gamper, N. and Peers, C. (2013) Carbon monoxide inhibition of Cav3.2 T-type Ca2+ channels reveals tonic modulation by thioredoxin. FASEB Journal, 27 (8). pp. 3395-3407. ISSN 0892-6638 doi: https://doi.org/10.1096/fj.13-227249

Dallas, M. L., Yang, Z., Boyle, J. P., Boycott, H. E., Scragg, J. L., Milligan, C. J., Elies, J., Duke, A., Thireau, J., Reboul, C., Richard, S., Bernus, O., Steele, D. S. and Peers, C. (2012) Carbon monoxide induces cardiac arrhythmia via induction of the late Na+ current. American Journal of Respiratory and Critical Care Medicine, 186 (7). pp. 648-656. ISSN 1535-4970 doi: https://doi.org/10.1164/rccm.201204-0688OC

Hettiarachchi, N. T., Boyle, J. P., Bauer, C. C., Dallas, M. L., Pearson, H. A., Hara, S., Gamper, N. and Peers, C. (2012) Peroxynitrite mediates disruption of Ca2+ homeostasis by carbon monoxide via Ca2+ ATPase degradation. Antioxidants & Redox Signaling, 17 (5). pp. 744-755. ISSN 1523-0864

Al-Owais, M. M. A., Scragg, J. L., Dallas, M. L., Boycott, H. E., Warburton, P., Chakrabarty, A., Boyle, J. P. and Peers, C. (2012) Carbon monoxide mediates the anti-apoptotic effects of heme oxygenase-1 in medulloblastoma DAOY cells via K+ channel inhibition. The Journal of Biological Chemistry, 287 (29). pp. 24754-24764. ISSN 1083-351X doi: https://doi.org/10.1074/jbc.M112.357012

Peers, C., Bauer, C. C., Boyle, J. P., Scragg, J. L. and Dallas, M. L. (2012) Modulation of ion channels by hydrogen sulfide. Antioxidants & Redox Signaling, 17 (1). pp. 95-105. ISSN 1523-0864

Dallas, M. L., Boyle, J. P., Milligan, C. J., Sayer, R., Kerrigan, T. L., McKinstry, C., Lu, P., Mankouri, J., Harris, M., Scragg, J. L., Pearson, H. A. and Peers, C. (2011) Carbon monoxide protects against oxidant-induced apoptosis via inhibition of Kv2.1. FASEB Journal, 25 (5). pp. 1519-1530. ISSN 0892-6638 doi: https://doi.org/10.1096/fj.10-173450

Ikematsu , N., Dallas, M. L., Ross, F. A., Lewis , R. W., Rafferty , J. N., David , J. A., Surman, R., Peers, C., Hardie, D. G. and Evans, A. M. (2011) Phosphorylation of the voltage-gated potassium channel Kv2.1 by AMP-activated protein kinase regulates membrane excitability. Proceedings of the National Academy of Sciences of the United States of America, 108 (44). pp. 18132-18137. ISSN 0027-8424 doi: https://doi.org/10.1073/pnas.1106201108

Hettiarachchi, N. T., Dallas, M. L., Pearson, H. A., Bruce, G., Deuchars, S., Boyle, J. P. and Peers, C. (2010) Gap junction-mediated spontaneous Ca(2+) waves in differentiated cholinergic SN56 cells. Biochemical and Biophysical Research Communications, 397 (3). pp. 564-568. ISSN 0006-291X doi: https://doi.org/10.1016/j.bbrc.2010.05.159

Mankouri, J., Tedbury, P. R., Gretton, S., Hughes, M. E., Griffin, S. D. C., Dallas, M. L., Green, K. A., Hardie, D. G., Peers, C. and Harris, M. (2010) Enhanced hepatitis C virus genome replication and lipid accumulation mediated by inhibition of AMP-activated protein kinase. Proceedings of the National Academy of Sciences of the United States of America, 107 (25). pp. 11549-11554. ISSN 0027-8424 doi: https://doi.org/10.1073/pnas.0912426107

Dallas, M. L., Deuchars, S. A. and Deuchars, J. (2010) Immunopharmacology: utilizing antibodies as ion channel modulators. Expert Review of Clinical Pharmacology, 3 (3). pp. 281-289. ISSN 1751-2433 doi: https://doi.org/10.1586/ecp.10.18

Hettiarachchi, N. T., Parker, A., Dallas, M. L., Pennington, K., Hung, C.-C., Pearson, H. A., Boyle, J. P., Robinson, P. and Peers, C. (2009) Alpha-synuclein modulation of Ca2+ signaling in human neuroblastoma (SH-SY5Y) cells. Journal of Neurochemistry, 111 (5). pp. 1192-1201. ISSN 0022-3042 doi: https://doi.org/10.1111/j.1471-4159.2009.06411.x

Mankouri, J., Dallas, M. L., Hughes, M. E., Griffin, S. D. C., Macdonald, A., Peers, C. and Harris, M. (2009) Suppression of a pro-apoptotic K+ channel as a mechanism for hepatitis C virus persistence. Proceedings of the National Academy of Sciences of the United States of America, 106 (37). pp. 15903-15908. ISSN 0027-8424 doi: https://doi.org/10.1073/pnas.0906798106

Peers, C., Dallas, M. L. and Scragg, J. L. (2009) Ion channels as effectors in carbon monoxide signaling. Communicative & Integrative Biology, 2 (3). pp. 241-242. ISSN 1942-0889 doi: https://doi.org/10.1074/jbc.M8030372

Aley, P. K., Bauer, C. C., Dallas, M. L., Boyle, J. P., Porter, K. E. and Peers, C. (2009) Hypoxic modulation of ca(2+) signaling in human venous and arterial endothelial cells. The Journal of Membrane Biology, 227 (3). pp. 151-158. ISSN 1432-1424 doi: https://doi.org/10.1007/s00232-008-9147-z

Milligan, C. J., Li, J., Sukumar, P., Majeed, Y., Dallas, M. L., English, A., Emery, P., Porter, K. E., Smith, A. M., McFadzean, I., Beccano-Kelly, D., Bahnasi, Y., Cheong, A., Naylor, J., Zeng, F., Liu, X., Gamper, N., Jiang, L.-H., Pearson, H. A., Peers, C., Robertson, B. and Beech, D. J. (2009) Robotic multiwell planar patch-clamp for native and primary mammalian cells. Nature Protocols, 4 (2). pp. 244-255. ISSN 1750-2799 doi: https://doi.org/10.1038/nprot.2008.230

Scragg, J. L., Dallas, M. L., Wilkinson, J. A., Varadi, G. and Peers, C. (2008) Carbon monoxide inhibits L-type Ca2+ channels via redox modulation of key cysteine residues by mitochondrial reactive oxygen species. The Journal of Biological Chemistry, 283 (36). pp. 24412-24419. ISSN 1083-351X doi: https://doi.org/10.1074/jbc.M803037200

Dallas, M. L., Scragg, J. L. and Peers, C. (2008) Modulation of hTREK-1 by carbon monoxide. Neuroreport, 19 (3). pp. 345-348. ISSN 1473-558X doi: https://doi.org/10.1097/WNR.0b013e3282f51045

Dallas, M. L., Morris, N. P., Lewis, D. I., Deuchars, S. A. and Deuchars, J. (2008) Voltage-gated potassium currents within the dorsal vagal nucleus: inhibition by BDS toxin. Brain Research, 1189. pp. 51-57. ISSN 0006-8993 doi: https://doi.org/10.1016/j.brainres.2007.10.090

Boycott, H. E., Dallas, M., Boyle, J. P., Pearson, H. A. and Peers, C. (2007) Hypoxia suppresses astrocyte glutamate transport independently of amyloid formation. Biochemical and Biophysical Research Communications, 364 (1). pp. 100-104. ISSN 0006-291X doi: https://doi.org/10.1016/j.bbrc.2007.09.102

Edwards, I. J., Dallas, M. L., Poole, S. L., Milligan, C. J., Yanagawa, Y., Szabó, G., Erdélyi, F., Deuchars, S. A. and Deuchars, J. (2007) The neurochemically diverse intermedius nucleus of the medulla as a source of excitatory and inhibitory synaptic input to the nucleus tractus solitarii. The Journal of Neuroscience, 27 (31). pp. 8324-8333. ISSN 1529-2401 doi: https://doi.org/10.1523/JNEUROSCI.0638-07.2007

Scragg, J. L., Dallas, M. L. and Peers, C. (2007) Molecular requirements for L-type Ca2+ channel blockade by testosterone. Cell Calcium, 42 (1). pp. 11-15. ISSN 0143-4160 doi: https://doi.org/10.1016/j.ceca.2006.11.003

Dallas, M., Boycott, H. E., Atkinson, L., Miller, A., Boyle, J. P., Pearson, H. A. and Peers, C. (2007) Hypoxia suppresses glutamate transport in astrocytes. The Journal of Neuroscience, 27 (15). pp. 3946-55. ISSN 1529-2401

Dallas, M. L., Atkinson, L., Milligan, C. J., Morris, N. P., Lewis, D. I., Deuchars, S. A. and Deuchars, J. (2005) Localization and function of the Kv3.1b subunit in the rat medulla oblongata: focus on the nucleus tractus solitarii. Journal of Physiology, 562 (Pt 3). pp. 655-72. ISSN 0022-3751

Dallas, M., Deuchars, S. A. and Deuchars, J. (2005) Immunopharmacology - antibodies for specific modulation of proteins involved in neuronal function. Journal of Neuroscience Methods, 146 (2). pp. 133-48. ISSN 0165-0270 doi: https://doi.org/10.1016/j.jneumeth.2005.04.015

Book or Report Section

Bell, D. C. and Dallas, M. L. ORCID: https://orcid.org/0000-0002-5190-0522 (2022) Advancing ion channel research with automated patch clamp (APC) electrophysiology platforms. In: Zhou, L. (ed.) Ion Channels in Biophysics and Physiology. Advances in Experimental Medicine and Biology, 1349. Springer, Singapore, pp. 21-32, VI, 413. ISBN 9789811642531 doi: https://doi.org/10.1007/978-981-16-4254-8_2

Peers, C., Dallas, M. L., Boycott, H. E., Scragg, J. L., Pearson, H. A. and Boyle, J. P. (2009) Hypoxia and neurodegeneration. In: Peers, C., Haddad, G. G. and Chandel, N. S. (eds.) Hypoxia and Consequences: From Molecule to Malady. Annals of the New York Academy of Sciences (1177). New York Academy of Sciences, New York, pp. 169-177.

Dallas, M. L., Deuchars, S. A. and Deuchars, J. (2008) Modulation of potassium ion channel proteins utilising antibodies. In: Lippiat, J. D. (ed.) Potassium Channels. Methods in Molecular Biology, 491. Springer, pp. 247-55. ISBN 9781597455268