Number of items: 27.
Article
Mitchell, J. L., Dunster, J. L. ORCID: https://orcid.org/0000-0001-8986-4902, Kriek, N., Unsworth, A. J., Sage, T., Mohammed, Y. M. M., De Simone, I., Taylor, K. A. ORCID: https://orcid.org/0000-0002-4599-7727, Bye, A. P. ORCID: https://orcid.org/0000-0002-2061-2253, Ólafsson, G., Brunton, M., Mark, S., Dymott, L. D., Whyte, A., Ruparelia, N., Mckenna, C., Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 and Jones, C. I. ORCID: https://orcid.org/0000-0001-7537-1509
(2023)
The rate of platelet activation determines thrombus size and structure at arterial shear.
Journal of Thrombosis and Haemostasis, 21 (8).
pp. 2248-2259.
ISSN 1538-7836
doi: https://doi.org/10.1016/j.jtha.2023.03.044
Kuravi, S. J., Ahmed, N. S., Taylor, K. A. ORCID: https://orcid.org/0000-0002-4599-7727, Capes, E. M., Bye, A. ORCID: https://orcid.org/0000-0002-2061-2253, Unsworth, A. J., Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 and Pugh, N.
(2023)
Delineating zinc influx mechanisms during platelet activation.
International Journal of Molecular Sciences, 24 (14).
11689.
ISSN 1422-0067
doi: https://doi.org/10.3390/ijms241411689
Mitchell, J. L., Little, G., Bye, A. P. ORCID: https://orcid.org/0000-0002-2061-2253, Gaspar, R. S., Unsworth, A. J., Kriek, N., Sage, T., Stainer, A., Sangowawa, I., Morrow, G. B., Bastos, R. N., Shapiro, S., Desborough, M. J. R., Curry, N., Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352, Whyte, C. S., Mutch, N. J. and Jones, C. I. ORCID: https://orcid.org/0000-0001-7537-1509
(2023)
Platelet factor XIII-A regulates platelet function and promotes clot retraction and stability.
Research and Practice in Thrombosis and Haemostasis, 7 (5).
100200.
ISSN 2475-0379
doi: https://doi.org/10.1016/j.rpth.2023.100200
Mitchell, J. L., Khan, D., Rana, R. H., Kriek, N., Unsworth, A. J., Sage, T., Bye, A. P. ORCID: https://orcid.org/0000-0002-2061-2253, Laffan, M., Shapiro, S., Thakurta, A., Grech, H., Ramasamy, K. and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352
(2023)
Multiple myeloma and its treatment contribute to increased platelet reactivity.
Platelets, 34 (1).
2264940.
ISSN 1369-1635
doi: https://doi.org/10.1080/09537104.2023.2264940
Kriek, N., Nock, S. H., Sage, T., Khalifa, B., Bye, A. P. ORCID: https://orcid.org/0000-0002-2061-2253, Mitchell, J. L., Thomson, S., McLaughlin, M. G., Jones, S., Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 and Unsworth, A. J. ORCID: https://orcid.org/0000-0003-3809-5984
(2022)
Cucurbitacins elicit anti-platelet activity via perturbation of the cytoskeleton and integrin function.
Thrombosis and Haemostasis, 122 (07).
pp. 1115-1129.
ISSN 0340-6245
doi: https://doi.org/10.1055/a-1788-5322
Dunster, J. ORCID: https://orcid.org/0000-0001-8986-4902, Bye, A. ORCID: https://orcid.org/0000-0002-2061-2253, Kriek, N., Sage, T., Mitchell, J., Kempster, C., Batista, J., KcKinney, H., Thomas, P., Jones, C. ORCID: https://orcid.org/0000-0001-7537-1509, Downes, K., Unsworth, A. and Gibbins, J. ORCID: https://orcid.org/0000-0002-0372-5352
(2021)
Multi-parameter phenotyping of platelet reactivity for stratification of human cohorts.
Blood Advances, 5 (20).
pp. 4017-4030.
ISSN 2473-9529
doi: https://doi.org/10.1182/bloodadvances.2020003261
Unsworth, A. J., Bye, A. P. ORCID: https://orcid.org/0000-0002-2061-2253, Sage, T., Gaspar, R. S., Eaton, N., Drew, C., Stainer, A., Kriek, N., Volberding, P. J., Hutchinson, J. L., Riley, R., Jones, S., Mundell, S. J., Cui, W., Falet, H. and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352
(2021)
Anti-platelet properties of Pim kinase inhibition is mediated through disruption of thromboxane A2 receptor signalling.
Haematologica, 106 (7).
ISSN 1592-8721
doi: https://doi.org/10.3324/haematol.2019.223529
Sahli, K. A., Flora, G. D., Sasikumar, P., Maghrabi, A. H., Holbrook, L., AlOuda, S. K., Elgheznawy, A., Sage, T., Stainer, A. R., Adiyaman, R., AboHassan, M., Crescente, M., Kriek, N., Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517, Bye, A. P. ORCID: https://orcid.org/0000-0002-2061-2253, Unsworth, A. J., Jones, C. I. ORCID: https://orcid.org/0000-0001-7537-1509, McGuffin, L. J. ORCID: https://orcid.org/0000-0003-4501-4767 and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352
(2021)
Structural, functional and mechanistic insights uncover the fundamental role of orphan connexin-62 in platelets.
Blood, 137 (6).
pp. 830-843.
ISSN 0006-4971
doi: https://doi.org/10.1182/blood.2019004575
Dunster, J. L. ORCID: https://orcid.org/0000-0001-8986-4902, Unsworth, A. J., Bye, A. P. ORCID: https://orcid.org/0000-0002-2061-2253, Haining, E. J.,, Sowa, M. A., Di, Y., Sage, T., Pallini, C., Pike, J. A., Hardy, A. T., Nieswandt, B., García, Á., Watson, S. P., Poulter, N. S., Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 and Pollitt, A. Y. ORCID: https://orcid.org/0000-0001-8706-5154
(2020)
Interspecies differences in protein expression do not impact the spatiotemporal regulation of glycoprotein VI mediated activation.
Journal of Thrombosis and Haemostasis, 18 (2).
pp. 485-496.
ISSN 1538-7836
doi: https://doi.org/10.1111/jth.14673
Flora, G. D., Sahli, K. A., Sasikumar, P., Holbrook, L.-M., Stainer, A. R., Alouda, S. K., Crescente, M., Sage, T., Unsworth, A. J. and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352
(2019)
Non-genomic effects of the Pregnane X Receptor negatively regulate platelet functions, thrombosis and haemostasis.
Scientific Reports, 9 (1).
17210.
ISSN 2045-2322
doi: https://doi.org/10.1038/s41598-019-53218-x
Stainer, A., Sasikumar, P., Bye, A. ORCID: https://orcid.org/0000-0002-2061-2253, Unsworth, A., Holbrook, L., Tindall, M., Lovegrove, J. ORCID: https://orcid.org/0000-0001-7633-9455 and Gibbins, J. ORCID: https://orcid.org/0000-0002-0372-5352
(2019)
Quercetin and its methylated metabolites possess anti-thrombotic properties that interact with aspirin to enhance its anti-platelet effects.
TH Open, 3 (3).
e244-e258.
ISSN 2512-9465
doi: https://doi.org/10.1055/s-0039-1694028
Unsworth, A. J., Bombik, I., Pinto-Fernandez, A., McGouran, J. F., Konietzny, R., Zahedi, R. P., Watson, S. P., Kessler, B. M. and Pears, C. J.
(2019)
Human platelet protein ubiquitylation and changes
following GPVI activation.
Thrombosis and Haemostasis, 119 (1).
pp. 104-116.
ISSN 0340-6245
doi: https://doi.org/10.1055/s-0038-1676344
Unsworth, A. J., Bye, A. P. ORCID: https://orcid.org/0000-0002-2061-2253, Kriek, N., Sage, T., Osborne, A. A., Donaghy, D. and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352
(2019)
Cobimetinib and trametinib inhibit platelet MEK but do not cause platelet dysfunction.
Platelets, 30 (6).
pp. 762-772.
ISSN 0953-7104
doi: https://doi.org/10.1080/09537104.2018.1514107
Stainer, A. R., Sasikumar, P., Bye, A. P. ORCID: https://orcid.org/0000-0002-2061-2253, Unsworth, A. P., Holbrook, L. M., Tindall, M., Lovegrove, J. A. ORCID: https://orcid.org/0000-0001-7633-9455 and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352
(2019)
The metabolites of the dietary flavonoid quercetin possess potent antithrombotic activity, and interact with aspirin to enhance antiplatelet effects.
TH Open, 3 (3).
e244-e258.
ISSN 2512-9465
doi: https://doi.org/10.1055/s-0039-1694028
Sasikumar, P., AlOuda, K. S., Kaiser, W. J., Holbrook, L. M., Kriek, N., Unsworth, A. J., Bye, A. P. ORCID: https://orcid.org/0000-0002-2061-2253, Sage, T., Ushioda, R. W., Nagata, K., Farndale, R. W. and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352
(2018)
The chaperone protein HSP47: a platelet collagen binding protein that contributes to thrombosis and haemostasis.
Journal of Thrombosis and Haemostasis, 16 (5).
pp. 946-959.
ISSN 1538-7933
doi: https://doi.org/10.1111/jth.13998
Unsworth, A. J., Flora, G. D. and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352
(2018)
Non-genomic effects of nuclear receptors: insights from the anucleate platelet.
Cardiovascular Research, 114 (5).
pp. 645-655.
ISSN 0008-6363
doi: https://doi.org/10.1093/cvr/cvy044
Bye, A. P. ORCID: https://orcid.org/0000-0002-2061-2253, Unsworth, A. J., Desborough, M. J., Hildyard, C. A. T., Appleby, N., Bruce, D., Kriek, N., Nock, S. H., Sage, T., Hughes, C. E. ORCID: https://orcid.org/0000-0002-9790-5820 and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352
(2017)
Severe platelet dysfunction in NHL patients receiving ibrutinib is absent in patients receiving acalabrutinib.
Blood Advances, 1 (26).
pp. 2610-2623.
ISSN 2473-9529
doi: https://doi.org/10.1182/bloodadvances.2017011999
Unsworth, A. J., Bye, A. P. ORCID: https://orcid.org/0000-0002-2061-2253, Tannetta, D. S., Desborough, M. J. R., Kriek, N., Sage, T., Allan, H. E., Crescente, M., Yaqoob, P. ORCID: https://orcid.org/0000-0002-6716-7599, Warner, T. D., Jones, C. I. ORCID: https://orcid.org/0000-0001-7537-1509 and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352
(2017)
Farnesoid X receptor and liver X receptor ligands initiate formation of coated platelets.
Arteriosclerosis, thrombosis, and vascular biology, 37 (8).
pp. 1482-1493.
ISSN 1524-4636
doi: https://doi.org/10.1161/ATVBAHA.117.309135
Unsworth, A. J., Flora, G. D., Sasikumar, P., Bye, A. P. ORCID: https://orcid.org/0000-0002-2061-2253, Sage, T., Kriek, N., Crescente, M. and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352
(2017)
RXR ligands negatively regulate thrombosis and hemostasis.
Arteriosclerosis Thrombosis and Vascular Biology, 37 (5).
pp. 812-822.
ISSN 1524-4636
doi: https://doi.org/10.1161/ATVBAHA.117.309207
Unsworth, A. J., Kriek, N., Bye, A. P. ORCID: https://orcid.org/0000-0002-2061-2253, Naran, K., Sage, T., Flora, G. D. and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352
(2017)
PPARγ agonists negatively regulate αIIbβ3 integrin outside-in signalling and platelet function through upregulation of protein kinase A activity.
Journal of Thrombosis and Haemostasis, 15 (2).
pp. 356-369.
ISSN 1538-7933
doi: https://doi.org/10.1111/jth.13578
Moraes, L. A., Unsworth, A. J., Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517, Ali, M. S., Sasikumar, P., Sage, T., Flora, G. D., Bye, A. P. ORCID: https://orcid.org/0000-0002-2061-2253, Kriek, N., Dorchies, E., Molendi-Coste, O., Dombrowicz, D., Staels, B., Bishop-Bailey, D. and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352
(2016)
Farnesoid X Receptor and its ligands inhibit the function of platelets.
Arteriosclerosis Thrombosis and Vascular Biology, 36 (12).
pp. 2324-2333.
ISSN 1524-4636
doi: https://doi.org/10.1161/ATVBAHA.116.308093
Bye, A. P. ORCID: https://orcid.org/0000-0002-2061-2253, Unsworth, A. J. and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352
(2016)
Platelet signaling: a complex interplay between inhibitory and activatory networks.
Journal of Thrombosis and Haemostasis, 14 (5).
pp. 918-930.
ISSN 1538-7933
doi: https://doi.org/10.1111/jth.13302
Bye, A. P. ORCID: https://orcid.org/0000-0002-2061-2253, Unsworth, A. J., Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517, Stainer, A. R., Fry, M. J. and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352
(2015)
Ibrutinib inhibits platelet integrin αIIbβ3 outside-in signaling and thrombus stability but not adhesion to collagen.
Arteriosclerosis Thrombosis and Vascular Biology, 35 (11).
pp. 2326-2335.
ISSN 1524-4636
doi: https://doi.org/10.1161/ATVBAHA.115.306130
Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517, Roweth, H., Ali, M., Unsworth, A., Stainer, A., Flora, G., Crescente, M., Jones, C. ORCID: https://orcid.org/0000-0001-7537-1509, Moraes, L. and Gibbins, J. ORCID: https://orcid.org/0000-0002-0372-5352
(2015)
Pharmacological actions of nobiletin in the modulation of platelet function.
British Journal of Pharmacology, 172 (16).
pp. 4133-4145.
ISSN 0007-1188
doi: https://doi.org/10.1111/bph.13191
Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517, Sage, T., Rana, R. H., Schenk, M. P., Ali, M. S., Unsworth, A. J., Jones, C. I. ORCID: https://orcid.org/0000-0001-7537-1509, Stainer, A. R., Kriek, N. K., Moraes, L. A. and Gibbins, J. ORCID: https://orcid.org/0000-0002-0372-5352
(2015)
EphB2 regulates contact-dependent and independent signalling to control platelet function.
Blood, 125 (4).
pp. 720-730.
ISSN 0006-4971
doi: https://doi.org/10.1182/blood-2014-06-585083
Book or Report Section
Bye, A. ORCID: https://orcid.org/0000-0002-2061-2253, Ilkan, Z., Unsworth, A. and Jones, C. ORCID: https://orcid.org/0000-0001-7537-1509
(2018)
Immobilization of nonactivated unfixed platelets for real-time single-cell analysis.
In: Gibbins, J. ORCID: https://orcid.org/0000-0002-0372-5352 and Mahaut-Smith, M. (eds.)
Platelets and Megakaryocytes (Volume 4, Advanced Protocols and Perspectives).
Methods in Molecular Biology, 1812.
Springer Protocols, pp. 1-11.
ISBN 9781493985845
Bye, A. P. ORCID: https://orcid.org/0000-0002-2061-2253, Unsworth, A. J. and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352
(2018)
Screening and high-throughput platelet assays.
In: Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 and Mahaut-Smith, M. (eds.)
Platelets and Megakaryocytes: Volume 4, Advanced Protocols and Perspectives.
Humana Press, New York, pp. 81-94.
ISBN 9781493985845
doi: https://doi.org/10.1007/978-1-4939-8585-2_5
This list was generated on Wed Dec 4 21:39:37 2024 UTC.