Article

Keane, P. M. ORCID: https://orcid.org/0000-0003-2828-8512, Zehe, C. ORCID: https://orcid.org/0000-0002-3213-5669, Poynton, F. E., Bright, S. A., Estayalo-Adrián, S. ORCID: https://orcid.org/0000-0002-2896-7059, Devereux, S. J., Donaldson, P. M. ORCID: https://orcid.org/0000-0002-0305-9142, Sazanovich, I. V. ORCID: https://orcid.org/0000-0002-8000-7645, Towrie, M., Botchway, S. W., Cardin, C. J. ORCID: https://orcid.org/0000-0002-2556-9995, Williams, D. C., Gunnlaugsson, T. ORCID: https://orcid.org/0000-0003-4814-6853, Long, C. ORCID: https://orcid.org/0000-0002-9484-8744, Kelly, J. M. ORCID: https://orcid.org/0000-0002-3706-1777 and Quinn, S. J. ORCID: https://orcid.org/0000-0002-7773-8842 (2022) Time-resolved infra-red studies of photo-excited porphyrins in the presence of nucleic acids and in HeLa tumour cells: insights into binding site and electron transfer dynamics. Physical Chemistry Chemical Physics, 24 (44). pp. 27524-27531. ISSN 1463-9076 doi: https://doi.org/10.1039/d2cp04604k

Keane, P. M. ORCID: https://orcid.org/0000-0003-2828-8512, O'Sullivan, K., Poynton, F. E., Poulsen, B. C., Sazanovich, I. V., Towrie, M., Cardin, C. J. ORCID: https://orcid.org/0000-0002-2556-9995, Sun, X.-Z., George, M. W. ORCID: https://orcid.org/0000-0002-7844-1696, Gunnlaugsson, T. ORCID: https://orcid.org/0000-0003-4814-6853, Quinn, S. J. ORCID: https://orcid.org/0000-0002-7773-8842 and Kelly, J. M. ORCID: https://orcid.org/0000-0002-3706-1777 (2020) Understanding the factors controlling the photo-oxidation of natural DNA by enantiomerically pure intercalating ruthenium polypyridyl complexes through TA/TRIR studies with polydeoxynucleotides and mixed sequence oligodeoxynucleotides. Chemical Science, 11 (32). pp. 8600-8609. ISSN 2041-6539 doi: https://doi.org/10.1039/d0sc02413a

Keane, P. M., Tory, J., Towrie, M., Sazanowich, I. V., Cardin, C. J. ORCID: https://orcid.org/0000-0002-2556-9995, Quinn, S. J., Hartl, F. ORCID: https://orcid.org/0000-0002-7013-5360, Kelly, J. M. and Long, C. (2019) Spectro-electrochemical studies on [Ru(TAP)2(dppz)]2+ - insights into the mechanism of its photosensitized oxidation of oligonucleotides. Inorganic Chemistry, 58 (1). pp. 663-671. ISSN 0020-1669 doi: https://doi.org/10.1021/acs.inorgchem.8b02859

Keane, P. M., Hall, J. P. ORCID: https://orcid.org/0000-0003-3716-4378, Poynton, F. E., Poulson, B. C., Gurung, S. P., Clark, I. P., Sazanovich, I. V., Towrie, M., Gunnlaugsson, T., Quinn, S. J., Cardin, C. J. ORCID: https://orcid.org/0000-0002-2556-9995 and Kelly, J. M. (2017) Inosine can increase DNA's susceptibility to photo-oxidation by a Ru(II) complex due to structural change in the minor groove. Chemistry - A European Journal, 23 (43). pp. 10344-10351. ISSN 0947-6539 doi: https://doi.org/10.1002/chem.201701447

Hall, J. P. ORCID: https://orcid.org/0000-0003-3716-4378, Keane, P. M., Beer, H., Buchner, K., Winter, G., Sorensen, T. L., Cardin, D. J., Brazier, J. A. ORCID: https://orcid.org/0000-0002-4952-584X and Cardin, C. J. ORCID: https://orcid.org/0000-0002-2556-9995 (2016) Delta chirality ruthenium ‘light-switch’ complexes can bind in the minor groove of DNA with five different binding modes. Nucleic Acids Research, 44 (19). pp. 9472-9482. ISSN 1362-4962 doi: https://doi.org/10.1093/nar/gkw753

Keane, P. M., Baptista, F. R., Gurung, S. P., Devereux, S. J., Sazanovich, I. V., Towrie, M., Brazier, J. A. ORCID: https://orcid.org/0000-0002-4952-584X, Cardin, C. J. ORCID: https://orcid.org/0000-0002-2556-9995, Kelly, J. M. and Quinn, S. J. (2016) Long-lived excited-state dynamics of i-motif structures probed by time-resolved infrared spectroscopy. ChemPhysChem, 17 (9). pp. 1281-1287. ISSN 1439-7641 doi: https://doi.org/10.1002/cphc.201501183

Poynton, F. E., Hall, J. P. ORCID: https://orcid.org/0000-0003-3716-4378, Keane, P. M., Schwarz, C., Sazanovich, I. V., Towrie, M., Gunnlaugsson, T., Cardin, C. J. ORCID: https://orcid.org/0000-0002-2556-9995, Cardin, D. J., Quinn, S. J., Long, C. and Kelly, J. M. (2016) Direct observation by time-resolved infrared spectroscopy of the bright and the dark excited states of the [Ru(phen)2(dppz)]2+ light-switch compound in solution and when bound to DNA. Chemical Science, 7 (5). pp. 3075-3084. ISSN 1478-6524 doi: https://doi.org/10.1039/C5SC04514B

Keane, P. M., Poynton, F. E., Hall, J. P. ORCID: https://orcid.org/0000-0003-3716-4378, Clark, I. P., Sazanovich, I. V., Towrie, M., Gunnlaugsson, T., Quinn, S. J., Cardin, C. J. ORCID: https://orcid.org/0000-0002-2556-9995 and Kelly, J. M. (2015) Monitoring guanine photo-oxidation by enantiomerically resolved Ru(II) dipyridophenazine complexes using inosine-substituted oligonucleotides. Faraday Discussions, 185. pp. 455-469. ISSN 1364-5498 doi: https://doi.org/10.1039/c5fd00085h

Hall, J. P. ORCID: https://orcid.org/0000-0003-3716-4378, Poynton, F. E., Keane, P. M., Gurung, S. P., Brazier, J. A. ORCID: https://orcid.org/0000-0002-4952-584X, Cardin, D. J., Winter, G., Gunnlaugsson, T., Sazanovich, I. V., Towrie, M., Cardin, C. J. ORCID: https://orcid.org/0000-0002-2556-9995, Kelly, J. M. and Quinn, S. J. (2015) Monitoring one-electron photo-oxidation of guanine in DNA crystals using ultrafast infrared spectroscopy. Nature Chemistry, 7. pp. 961-967. ISSN 1755-4330 doi: https://doi.org/10.1038/nchem.2369

Keane, P. M., Poynton, F. E., Hall, J. P. ORCID: https://orcid.org/0000-0003-3716-4378, Sazanovich, I. V., Towrie, M., Gunnlaugsson, T., Quinn, S. J., Cardin, C. J. ORCID: https://orcid.org/0000-0002-2556-9995 and Kelly, J. M. (2015) Reversal of a single base pair step controls guanine photo-oxidation by an intercalating Ru(II) dipyridophenazine complex. Angewandte Chemie-International Edition, 54 (29). pp. 8364-8368. ISSN 1433-7851 doi: https://doi.org/10.1002/anie.201502608

Keane, P. M., Poynton, F. E., Hall, J. P. ORCID: https://orcid.org/0000-0003-3716-4378, Clark, I. P., Sazanovich, I. V., Towrie, M., Gunnlaugsson, T., Quinn, S. J., Cardin, C. J. ORCID: https://orcid.org/0000-0002-2556-9995 and Kelly, J. M. (2015) Enantiomeric conformation controls rate and yield of photoinduced electron transfer in DNA sensitized by Ru(II) Dipyridophenazine complexes. Journal of Physical Chemistry Letters, 6 (4). pp. 734-738. ISSN 1948-7185 doi: https://doi.org/10.1021/jz502743q

Devereux, S. J., Keane, P. M., Vasudevan, S., Sazanovich, I. V., Towrie, M., Cao, Q., Sun, X.-Z., George, M. W., Cardin, C. J. ORCID: https://orcid.org/0000-0002-2556-9995, Kane-Maguire, N. A. P., Kelly, J. M. and Quinn, S. J. (2014) Study of picosecond processes of an intercalated dipyridophenazine Cr(iii) complex bound to defined sequence DNAs using transient absorption and time-resolved infrared methods. Dalton Transactions, 43 (47). pp. 17606-17609. ISSN 1364-5447 doi: https://doi.org/10.1039/C4DT01989J