Number of items: 8.
Article
Meijles, D. N., Cull, J. J., Cooper, S. T. E., Markou, T., Hardyman, M. A., Fuller, S. J., Alharbi, H. O., Haines, Z. H. R., Alcantara Alonso, V., Glennon, P. E., Sheppard, M. N., Sugden, P. H. and Clerk, A.
ORCID: https://orcid.org/0000-0002-5658-0708
(2021)
The anti-cancer drug dabrafenib is not cardiotoxic and inhibits cardiac remodelling and fibrosis in a murine model of hypertension.
Clinical Science, 135 (14).
pp. 1631-1647.
ISSN 0143-5221
doi: https://doi.org/10.1042/CS20210192
Meijles, D. N., Fuller, S. J., Cull, J. J., Alharbi, H. O., Cooper, S. T. E., Sugden, P. H. and Clerk, A.
ORCID: https://orcid.org/0000-0002-5658-0708
(2021)
The insulin receptor family and protein kinase B (Akt) are activated in the heart by alkaline pH and α1-adrenergic receptors.
Biochemical Journal, 478 (11).
pp. 2059-2079.
ISSN 1470-8728
doi: https://doi.org/10.1042/BCJ20210144
Novelli, E. M., Little-Ihrig, L., Knupp, H. E., Rogers, N. M., Yao, M., Baust, J. J., Meijles, D., St. Croix, C. M., Ross, M. A., Pagano, P. J., DeVallance, E. R., Miles, G., Potoka, K. P., Isenberg, J. S. and Gladwin, M. T.
(2019)
Vascular TSP1-CD47 signaling promotes sickle cell-associated arterial vasculopathy and pulmonary hypertension in mice.
American Journal of Physiology-Lung Cellular and Molecular Physiology, 316 (6).
L1150-L1164.
ISSN 1522-1504
doi: https://doi.org/10.1152/ajplung.00302.2018
Meijles, D. N., Zoumpoulidou, G., Markou, T., Rostron, K. A., Patel, R., Lay, K., Handa, B. S., Wong, B., Sugden, P. H. and Clerk, A.
(2019)
The cardiomyocyte "redox rheostat": Redox signalling via the AMPK-mTOR axis and regulation of gene and protein expression balancing survival and death.
Journal of molecular and cellular cardiology, 129.
pp. 118-129.
ISSN 1095-8584
doi: https://doi.org/10.1016/j.yjmcc.2019.02.006
Meijles, D. N., Fan, L. M., Ghazaly, M. M., Howlin, B., Krönke, M., Brooks, G. and Li, J.-m.
(2016)
p22phox C242T SNP inhibits inflammatory oxidative damage to endothelial cells and vessels.
Circulation, 133 (24).
pp. 2391-2403.
ISSN 1524-4539
doi: https://doi.org/10.1161/CIRCULATIONAHA.116.021993
Sahoo, S., Meijles, D. N., Al Ghouleh, I., Tandon, M., Cifuentes-Pagano, E., Sembrat, J., Rojas, M., Goncharova, E. and Pagano, P. J.
(2016)
MEF2C-MYOCD and leiomodin1 suppression by miRNA-214 promotes smooth muscle cell phenotype switching in pulmonary arterial hypertension.
PLoS ONE, 11 (5).
e0153780.
ISSN 1932-6203
doi: https://doi.org/10.1371/journal.pone.0153780
Meijles, D. N., Fan, L. M., Howlin, B. J. and Li, J.-m.
(2014)
Molecular insights of p47phox phosphorylation dynamics in the regulation of NADPH oxidase activation and superoxide production.
The Journal of Biological Chemistry, 289 (33).
pp. 22759-22770.
ISSN 1083-351X
doi: https://doi.org/10.1074/jbc.M114.561159
Patent
St George's Hospital Medical School
(2020)
Treatment of fibrosis With RAF inhibitors.
WO 2020/161477.
doi: WO 2020/161477
This list was generated on Mon Jan 30 08:07:39 2023 UTC.