Article

Zhu, X., Gayathri, R., Sriram Manasa, V., Abirami, K., Bhupathiraju, S. N., Mohan Anjana, R., Givens, D. I. ORCID: https://orcid.org/0000-0002-6754-6935, Wijeyesekera, A. ORCID: https://orcid.org/0000-0001-6151-5065, Sudha, V., Mohan, V. and Vimaleswaran, K. S. ORCID: https://orcid.org/0000-0002-8485-8930 (2025) Effects of lacto-vegetarian and vegan diets on glycemic responses and metabolite profiles in healthy adults: a randomized trial using continuous glucose monitoring and targeted metabolomics. Clinical Nutrition, 49. pp. 138-148. ISSN 1532-1983 doi: 10.1016/j.clnu.2025.04.018

Sanz Morales, P., Wijeyesekera, A. ORCID: https://orcid.org/0000-0001-6151-5065, Robertson, M.D., Kennedy, J., Major, G., Boulange, C.L. and Gibson, G.R. ORCID: https://orcid.org/0000-0002-0566-0476 (2025) A focus group study to assess perspectives of patients with irritable bowel syndrome on human milk oligosaccharides and lifestyle insights. European Journal of Nutrition, 64. 196. ISSN 1436-6215 doi: 10.1007/s00394-025-03719-5

Zhu, X., Ventura, E. F., Bansal, S., Wijeyesekera, A. ORCID: https://orcid.org/0000-0001-6151-5065 and Vimaleswaran, K. S. ORCID: https://orcid.org/0000-0002-8485-8930 (2025) Integrating genetics, metabolites, and clinical characteristics in predicting cardiometabolic health outcomes using machine learning algorithms - a systematic review. Computers in Biology and Medicine, 186. 109661. ISSN 1879-0534 doi: 10.1016/j.compbiomed.2025.109661

Sanz Morales, P. ORCID: https://orcid.org/0000-0002-0719-2282, Wijeyesekera, A. ORCID: https://orcid.org/0000-0001-6151-5065, Robertson, M. D., Major, G., Boulangé, C. L., Jackson, P. P. J. ORCID: https://orcid.org/0000-0003-0098-4719, Poveda Turrado, C. G. and Gibson, G. R. ORCID: https://orcid.org/0000-0002-0566-0476 (2025) An in vitro batch culture study to assess the fermentation of human milk oligosaccharides by faecal microbiota from healthy and irritable bowel syndrome stool donors. Gut Microbiome, 6. e4. ISSN 2632-2897 doi: 10.1017/gmb.2025.2

Farraj, A., Akeredolu, T., Wijeyesekera, A. ORCID: https://orcid.org/0000-0001-6151-5065 and Mills, C. E. ORCID: https://orcid.org/0000-0002-8313-3700 (2024) Coffee and cardiovascular health: a review of literature. Nutrients, 16 (24). 4257. ISSN 2072-6643 doi: 10.3390/nu16244257

Jackson, P. P. J., Wijeyesekera, A. ORCID: https://orcid.org/0000-0001-6151-5065, Williams, C. M. ORCID: https://orcid.org/0000-0003-4452-671X, Theis, S., van Harsselaar, J. and Rastall, R. A. (2023) Inulin-type fructans and 2'fucosyllactose alter both microbial composition and appear to alleviate stress-induced mood state in a working population compared to placebo (maltodextrin): the EFFICAD Trial, a randomized, controlled trial. The American Journal of Clinical Nutrition, 118 (5). pp. 938-955. ISSN 1938-3207 doi: 10.1016/j.ajcnut.2023.08.016

Jackson, P. P. J. ORCID: https://orcid.org/0000-0003-0098-4719, Wijeyesekera, A. ORCID: https://orcid.org/0000-0001-6151-5065 and Rastall, R. A. (2023) Oligofructose alone and in combination with 2'fucosyllactose induces physiologically relevant changes in γ-aminobutyric acid and organic acid production compared to sole 2'fucosyllactose supplementation: an in vitro study. FEMS microbiology ecology, 99 (9). fiad100. ISSN 0168-6496 doi: 10.1093/femsec/fiad100

Monteagudo-Mera, A., Shalunkhe, A., Duhduh, A., Walton, G. ORCID: https://orcid.org/0000-0001-5426-5635, Gibson, G. R. ORCID: https://orcid.org/0000-0002-0566-0476, Pereira, D., Wijeyesekera, A. ORCID: https://orcid.org/0000-0001-6151-5065 and Andrews, S. C. ORCID: https://orcid.org/0000-0003-4295-2686 (2023) Impact of inorganic iron and haem on the human gut microbiota; an in vitro batch-culture approach. Frontiers in Microbiology, 14. 1074637. ISSN 1664-302X doi: 10.3389/fmicb.2023.1074637

Monteagudo-Mera, A., Fanti, V., Rodriguez-Sobstel, C., Gibson, G. ORCID: https://orcid.org/0000-0002-0566-0476, Wijeyesekera, A. ORCID: https://orcid.org/0000-0001-6151-5065, Karatzas, K.-A. and Chakrabarti, B. ORCID: https://orcid.org/0000-0002-6649-7895 (2023) Gamma aminobutyric acid production by commercially available probiotic strains. Journal of Applied Microbiology, 134 (2). lxac066. ISSN 1364-5072 doi: 10.1093/jambio/lxac066

Jackson, P. P. J., Wijeyesekera, A. ORCID: https://orcid.org/0000-0001-6151-5065, van Harsselaar, J., Theis, S. and Rastall, R. A. (2023) Oligofructose, 2'fucosyllactose and β-glucan in combination induce specific changes in microbial composition and short-chain fatty acid production compared to sole supplementation. Journal of Applied Microbiology, 134 (2). lxac069. ISSN 1364-5072 doi: 10.1093/jambio/lxac069

Jackson, P. P. J. ORCID: https://orcid.org/0000-0003-0098-4719, Wijeyesekera, A. ORCID: https://orcid.org/0000-0001-6151-5065 and Rastall, R. A. (2023) Inulin‐type fructans and short‐chain fructooligosaccharides—their role within the food industry as fat and sugar replacers and texture modifiers—what needs to be considered! Food Science & Nutrition, 11 (1). pp. 17-38. ISSN 2048-7177 doi: 10.1002/fsn3.3040

Jackson, P. P. J., Wijeyesekera, A. ORCID: https://orcid.org/0000-0001-6151-5065, Theis, S., Van Harsselaar, J. and Rastall, R. A. ORCID: https://orcid.org/0000-0003-1775-5226 (2023) Effects of food matrix on the prebiotic efficacy of inulin-type fructans: a randomised trial. Beneficial Microbes, 14 (4). pp. 317-334. ISSN 1876-2891 doi: 10.1163/18762891-20220120

Sanz Morales, P., Wijeyesekera, A. ORCID: https://orcid.org/0000-0001-6151-5065, Robertson, M. D., Jackson, P. P. J. and Gibson, G. R. ORCID: https://orcid.org/0000-0002-0566-0476 (2022) The potential role of human milk oligosaccharides in irritable bowel syndrome. Microorganisms, 10 (12). 2338. ISSN 2076-2607 doi: 10.3390/microorganisms10122338

Kean, I. R. L., Wagner, J., Wijeyesekera, A. ORCID: https://orcid.org/0000-0001-6151-5065, De Goffau, M., Thurston, S., Clark, J. A., White, D. K., Ridout, J., Agrawal, S., Kayani, R., O’Donnell, R., Ramnarayan, P., Peters, M. J., Klein, N., Holmes, E., Parkhill, J., Baker, S. and Pathan, N. (2022) Profiling gut microbiota and bile acid metabolism in critically ill children. Scientific Reports, 12 (1). 10432. ISSN 2045-2322 doi: 10.1038/s41598-022-13640-0

Jackson, P. P. J., Wijeyesekera, A. ORCID: https://orcid.org/0000-0001-6151-5065, Theis, S., van Harsselaar, J. and Rastall, R. A. (2022) Food for thought! Inulin-type fructans: does the food matrix matter? Journal of Functional Foods, 90. 104987. ISSN 1756-4646 doi: 10.1016/j.jff.2022.104987

Jackson, P. P. J., Wijeyesekera, A. ORCID: https://orcid.org/0000-0001-6151-5065 and Rastall, R. A. (2022) Determining the metabolic fate of human milk oligosaccharides: it may just be more complex than you think? Gut Microbiome, 3. e9. ISSN 2632-2897 doi: 10.1017/gmb.2022.8

Sayers, B. ORCID: https://orcid.org/0000-0003-2711-238X, Wijeyesekera, A. ORCID: https://orcid.org/0000-0001-6151-5065 and Gibson, G. ORCID: https://orcid.org/0000-0002-0566-0476 (2021) Exploring the potential of prebiotic and polyphenol-based dietary interventions for the alleviation of cognitive and gastrointestinal perturbations associated with military specific stressors. Journal of Functional Foods, 87. 104753. ISSN 1756-4646 doi: 10.1016/j.jff.2021.104753

Curi-Quinto, K., Sanchez, A., Lago-Berrocal, N., Penny, M., Murray, C., Nunes, R. ORCID: https://orcid.org/0000-0003-0829-4130, Favara, M., Wijeyesekera, A. ORCID: https://orcid.org/0000-0001-6151-5065, Lovegrove, J. ORCID: https://orcid.org/0000-0001-7633-9455, Soto-Caceres, V. and Vimaleswaran, K. S. ORCID: https://orcid.org/0000-0002-8485-8930 (2021) Role of government financial support and vulnerability char-acteristics associated with food insecurity during the COVID-19 pandemic among young Peruvians. Nutrients, 13 (10). 3546. ISSN 2072-6643 doi: 10.3390/nu13103546

Newland, G. A. I., Gibson, G. R. ORCID: https://orcid.org/0000-0002-0566-0476, Jackson, F. L. and Wijeyesekera, A. ORCID: https://orcid.org/0000-0001-6151-5065 (2021) Assessment of stool collection and storage conditions for in vitro human gut model studies. Journal of Microbiological Methods, 185. 106230. ISSN 0167-7012 doi: 10.1016/j.mimet.2021.106230

Lawson, M. A. E., O'Neill, I. J., Kujawska, M., Gowrinadh Javvadi, S., Wijeyesekera, A. ORCID: https://orcid.org/0000-0001-6151-5065, Flegg, Z., Chalklen, L. and Hall, L. J. (2020) Breast milk-derived human milk oligosaccharides promote Bifidobacterium interactions within a single ecosystem. ISME Journal, 14. pp. 635-648. ISSN 1751-7370 doi: 10.1038/s41396-019-0553-2

Scott, K. P., Grimaldi, R., Cunningham, M., Sarbini, S. R., Wijeyesekera, A. ORCID: https://orcid.org/0000-0001-6151-5065, Tang, M. L., Lee, J. C.-Y., Yau, Y. F., Ansell, J., Theis, S., Yang, K., Menon, R., Arfsten, J., Manurung, S., Gourineni, V. and Gibson, G. R. ORCID: https://orcid.org/0000-0002-0566-0476 (2020) Developments in understanding and applying prebiotics in research and practice - an ISAPP conference paper. Journal of Applied Microbiology, 128 (4). pp. 934-948. ISSN 1364-5072 doi: 10.1111/jam.14424

Wijeyesekera, A. ORCID: https://orcid.org/0000-0001-6151-5065, Wagner, J., De Goffau, M., Thurston, S., Rodrigues Sabino, A., Zaher, S., White, D., Ridout, J., Peters, M. J., Ramnarayan, P., Branco, R. G., Torok, M. E., Valla, F., Meyer, R., Klein, N., Frost, G., Parkhill, J., Holmes, E. and Pathan, N. (2019) Multi-compartment profiling of cacterial and host metabolites identifies intestinal dysbiosis and its functional consequences in the critically ill child. Critical care medicine, 47 (9). e727-e734. ISSN 1530-0293 doi: 10.1097/CCM.0000000000003841

Parkinson, J. R. C., Wijeyesekera, A. D. ORCID: https://orcid.org/0000-0001-6151-5065, Hyde, M. J., Singhal, A., Lucas, A., Holmes, E. and Modi, N. (2017) Early preterm nutrition and the urinary metabolome in young adult life: follow-up of a randomised controlled trial. BMJ Paediatrics Open, 1 (1). e000192. ISSN 2399-9772 doi: 10.1136/bmjpo-2017-000192

Basson, A. R. and Wijeyesekera, A. ORCID: https://orcid.org/0000-0001-6151-5065 (2017) Metabolic phenotyping for understanding the gut microbiome and host metabolic interplay. Emerging Topics in Life Sciences, 1 (4). pp. 325-332. ISSN 2397-8562 doi: 10.1042/ETLS20170079

Chekmeneva, E., dos Santos Correia, G., Chan, Q., Wijeyesekera, A. ORCID: https://orcid.org/0000-0001-6151-5065, Tin, A., Young, J. H., Elliott, P., Nicholson, J. K. and Holmes, E. (2017) Optimization and application of direct infusion nanoelectrospray HRMS method for large-scale urinary metabolic phenotyping in molecular epidemiology. Journal of Proteome Research, 16 (4). pp. 1646-1658. ISSN 1535-3907 doi: 10.1021/acs.jproteome.6b01003

Jackson, F., Georgakopoulou, N., Kaluarachchi, M., Kyriakides, M., Andreas, N., Przysiezna, N., Hyde, M. J., Modi, N., Nicholson, J. K., Wijeyesekera, A. ORCID: https://orcid.org/0000-0001-6151-5065 and Holmes, E. (2016) Development of a pipeline for exploratory metabolic profiling of infant urine. Journal of Proteome Research, 15 (9). pp. 3432-3440. ISSN 1535-3907 doi: 10.1021/acs.jproteome.6b00234

Baker, L., Lanz, B., Andreola, F., Ampuero, J., Wijeyesekera, A. ORCID: https://orcid.org/0000-0001-6151-5065, Holmes, E. and Deutz, N. (2016) New technologies – new insights into the pathogenesis of hepatic encephalopathy. Metabolic Brain Disease, 31 (6). pp. 1259-1267. ISSN 1573-7365 doi: 10.1007/s11011-016-9906-y

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Amiot, A., Dona, A. C., Wijeyesekera, A. ORCID: https://orcid.org/0000-0001-6151-5065, Tournigand, C., Baumgaertner, I., Lebaleur, Y., Sobhani, I. and Holmes, E. (2015) 1H NMR spectroscopy of fecal extracts enables detection of advanced colorectal neoplasia. Journal of Proteome Research, 14 (9). pp. 3871-3881. ISSN 1535-3907 doi: 10.1021/acs.jproteome.5b00277

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Book or Report Section

Athersuch, T. J. and Wijeyesekera, A. ORCID: https://orcid.org/0000-0001-6151-5065 (2018) NMR in environmental and nutritional research. In: Keun, H. C. (ed.) NMR-based Metabolomics. Royal Society of Chemistry, pp. 168-182. ISBN 9781849736435 doi: 10.1039/9781782627937-00168