2023

Jackson, P. P. J., Wijeyesekera, A. ORCID: https://orcid.org/0000-0001-6151-5065, Williams, C. M. ORCID: https://orcid.org/0000-0003-4452-671X, Theis, S., van Harsselaar, J. and Rastall, R. A. (2023) Inulin-type fructans and 2'fucosyllactose alter both microbial composition and appear to alleviate stress-induced mood state in a working population compared to placebo (maltodextrin): the EFFICAD Trial, a randomized, controlled trial. The American Journal of Clinical Nutrition, 118 (5). pp. 938-955. ISSN 1938-3207 doi: https://doi.org/10.1016/j.ajcnut.2023.08.016

Jackson, P. P. J. ORCID: https://orcid.org/0000-0003-0098-4719, Wijeyesekera, A. ORCID: https://orcid.org/0000-0001-6151-5065 and Rastall, R. A. (2023) Oligofructose alone and in combination with 2'fucosyllactose induces physiologically relevant changes in γ-aminobutyric acid and organic acid production compared to sole 2'fucosyllactose supplementation: an in vitro study. FEMS microbiology ecology, 99 (9). fiad100. ISSN 0168-6496 doi: https://doi.org/10.1093/femsec/fiad100

Monteagudo-Mera, A., Shalunkhe, A., Duhduh, A., Walton, G. ORCID: https://orcid.org/0000-0001-5426-5635, Gibson, G. R. ORCID: https://orcid.org/0000-0002-0566-0476, Pereira, D., Wijeyesekera, A. ORCID: https://orcid.org/0000-0001-6151-5065 and Andrews, S. C. ORCID: https://orcid.org/0000-0003-4295-2686 (2023) Impact of inorganic iron and haem on the human gut microbiota; an in vitro batch-culture approach. Frontiers in Microbiology, 14. 1074637. ISSN 1664-302X doi: https://doi.org/10.3389/fmicb.2023.1074637

Monteagudo-Mera, A., Fanti, V., Rodriguez-Sobstel, C., Gibson, G. ORCID: https://orcid.org/0000-0002-0566-0476, Wijeyesekera, A. ORCID: https://orcid.org/0000-0001-6151-5065, Karatzas, K.-A. and Chakrabarti, B. ORCID: https://orcid.org/0000-0002-6649-7895 (2023) Gamma aminobutyric acid production by commercially available probiotic strains. Journal of Applied Microbiology, 134 (2). lxac066. ISSN 1364-5072 doi: https://doi.org/10.1093/jambio/lxac066

Jackson, P. P. J., Wijeyesekera, A. ORCID: https://orcid.org/0000-0001-6151-5065, van Harsselaar, J., Theis, S. and Rastall, R. A. (2023) Oligofructose, 2'fucosyllactose and β-glucan in combination induce specific changes in microbial composition and short-chain fatty acid production compared to sole supplementation. Journal of Applied Microbiology, 134 (2). lxac069. ISSN 1364-5072 doi: https://doi.org/10.1093/jambio/lxac069

Jackson, P. P. J. ORCID: https://orcid.org/0000-0003-0098-4719, Wijeyesekera, A. ORCID: https://orcid.org/0000-0001-6151-5065 and Rastall, R. A. (2023) Inulin‐type fructans and short‐chain fructooligosaccharides—their role within the food industry as fat and sugar replacers and texture modifiers—what needs to be considered! Food Science & Nutrition, 11 (1). pp. 17-38. ISSN 2048-7177 doi: https://doi.org/10.1002/fsn3.3040

Jackson, P. P. J., Wijeyesekera, A. ORCID: https://orcid.org/0000-0001-6151-5065, Theis, S., Van Harsselaar, J. and Rastall, R. A. ORCID: https://orcid.org/0000-0003-1775-5226 (2023) Effects of food matrix on the prebiotic efficacy of inulin-type fructans: a randomised trial. Beneficial Microbes, 14 (4). pp. 317-334. ISSN 1876-2891 doi: https://doi.org/10.1163/18762891-20220120

2022

Sanz Morales, P., Wijeyesekera, A. ORCID: https://orcid.org/0000-0001-6151-5065, Robertson, M. D., Jackson, P. P. J. and Gibson, G. R. ORCID: https://orcid.org/0000-0002-0566-0476 (2022) The potential role of human milk oligosaccharides in irritable bowel syndrome. Microorganisms, 10 (12). 2338. ISSN 2076-2607 doi: https://doi.org/10.3390/microorganisms10122338

Kean, I. R. L., Wagner, J., Wijeyesekera, A. ORCID: https://orcid.org/0000-0001-6151-5065, De Goffau, M., Thurston, S., Clark, J. A., White, D. K., Ridout, J., Agrawal, S., Kayani, R., O’Donnell, R., Ramnarayan, P., Peters, M. J., Klein, N., Holmes, E., Parkhill, J., Baker, S. and Pathan, N. (2022) Profiling gut microbiota and bile acid metabolism in critically ill children. Scientific Reports, 12 (1). 10432. ISSN 2045-2322 doi: https://doi.org/10.1038/s41598-022-13640-0

Jackson, P. P. J., Wijeyesekera, A. ORCID: https://orcid.org/0000-0001-6151-5065, Theis, S., van Harsselaar, J. and Rastall, R. A. (2022) Food for thought! Inulin-type fructans: does the food matrix matter? Journal of Functional Foods, 90. 104987. ISSN 1756-4646 doi: https://doi.org/10.1016/j.jff.2022.104987

Jackson, P. P. J., Wijeyesekera, A. ORCID: https://orcid.org/0000-0001-6151-5065 and Rastall, R. A. (2022) Determining the metabolic fate of human milk oligosaccharides: it may just be more complex than you think? Gut Microbiome, 3. e9. ISSN 2632-2897 doi: https://doi.org/10.1017/gmb.2022.8

2021

Sayers, B. ORCID: https://orcid.org/0000-0003-2711-238X, Wijeyesekera, A. ORCID: https://orcid.org/0000-0001-6151-5065 and Gibson, G. ORCID: https://orcid.org/0000-0002-0566-0476 (2021) Exploring the potential of prebiotic and polyphenol-based dietary interventions for the alleviation of cognitive and gastrointestinal perturbations associated with military specific stressors. Journal of Functional Foods, 87. 104753. ISSN 1756-4646 doi: https://doi.org/10.1016/j.jff.2021.104753

Curi-Quinto, K., Sanchez, A., Lago-Berrocal, N., Penny, M., Murray, C., Nunes, R. ORCID: https://orcid.org/0000-0003-0829-4130, Favara, M., Wijeyesekera, A. ORCID: https://orcid.org/0000-0001-6151-5065, Lovegrove, J. ORCID: https://orcid.org/0000-0001-7633-9455, Soto-Caceres, V. and Vimaleswaran, K. S. ORCID: https://orcid.org/0000-0002-8485-8930 (2021) Role of government financial support and vulnerability char-acteristics associated with food insecurity during the COVID-19 pandemic among young Peruvians. Nutrients, 13 (10). 3546. ISSN 2072-6643 doi: https://doi.org/10.3390/nu13103546

Newland, G. A. I., Gibson, G. R. ORCID: https://orcid.org/0000-0002-0566-0476, Jackson, F. L. and Wijeyesekera, A. ORCID: https://orcid.org/0000-0001-6151-5065 (2021) Assessment of stool collection and storage conditions for in vitro human gut model studies. Journal of Microbiological Methods, 185. 106230. ISSN 0167-7012 doi: https://doi.org/10.1016/j.mimet.2021.106230

2020

Lawson, M. A. E., O'Neill, I. J., Kujawska, M., Gowrinadh Javvadi, S., Wijeyesekera, A. ORCID: https://orcid.org/0000-0001-6151-5065, Flegg, Z., Chalklen, L. and Hall, L. J. (2020) Breast milk-derived human milk oligosaccharides promote Bifidobacterium interactions within a single ecosystem. ISME Journal, 14. pp. 635-648. ISSN 1751-7370 doi: https://doi.org/10.1038/s41396-019-0553-2

Scott, K. P., Grimaldi, R., Cunningham, M., Sarbini, S. R., Wijeyesekera, A. ORCID: https://orcid.org/0000-0001-6151-5065, Tang, M. L., Lee, J. C.-Y., Yau, Y. F., Ansell, J., Theis, S., Yang, K., Menon, R., Arfsten, J., Manurung, S., Gourineni, V. and Gibson, G. R. ORCID: https://orcid.org/0000-0002-0566-0476 (2020) Developments in understanding and applying prebiotics in research and practice - an ISAPP conference paper. Journal of Applied Microbiology, 128 (4). pp. 934-948. ISSN 1364-5072 doi: https://doi.org/10.1111/jam.14424

2019

Wijeyesekera, A. ORCID: https://orcid.org/0000-0001-6151-5065, Wagner, J., De Goffau, M., Thurston, S., Rodrigues Sabino, A., Zaher, S., White, D., Ridout, J., Peters, M. J., Ramnarayan, P., Branco, R. G., Torok, M. E., Valla, F., Meyer, R., Klein, N., Frost, G., Parkhill, J., Holmes, E. and Pathan, N. (2019) Multi-compartment profiling of cacterial and host metabolites identifies intestinal dysbiosis and its functional consequences in the critically ill child. Critical care medicine, 47 (9). e727-e734. ISSN 1530-0293 doi: https://doi.org/10.1097/CCM.0000000000003841

2018

Athersuch, T. J. and Wijeyesekera, A. ORCID: https://orcid.org/0000-0001-6151-5065 (2018) NMR in environmental and nutritional research. In: Keun, H. C. (ed.) NMR-based Metabolomics. Royal Society of Chemistry, pp. 168-182. ISBN 9781849736435 doi: https://doi.org/10.1039/9781782627937-00168

2017

Parkinson, J. R. C., Wijeyesekera, A. D. ORCID: https://orcid.org/0000-0001-6151-5065, Hyde, M. J., Singhal, A., Lucas, A., Holmes, E. and Modi, N. (2017) Early preterm nutrition and the urinary metabolome in young adult life: follow-up of a randomised controlled trial. BMJ Paediatrics Open, 1 (1). e000192. ISSN 2399-9772 doi: https://doi.org/10.1136/bmjpo-2017-000192

Basson, A. R. and Wijeyesekera, A. ORCID: https://orcid.org/0000-0001-6151-5065 (2017) Metabolic phenotyping for understanding the gut microbiome and host metabolic interplay. Emerging Topics in Life Sciences, 1 (4). pp. 325-332. ISSN 2397-8562 doi: https://doi.org/10.1042/ETLS20170079

Chekmeneva, E., dos Santos Correia, G., Chan, Q., Wijeyesekera, A. ORCID: https://orcid.org/0000-0001-6151-5065, Tin, A., Young, J. H., Elliott, P., Nicholson, J. K. and Holmes, E. (2017) Optimization and application of direct infusion nanoelectrospray HRMS method for large-scale urinary metabolic phenotyping in molecular epidemiology. Journal of Proteome Research, 16 (4). pp. 1646-1658. ISSN 1535-3907 doi: https://doi.org/10.1021/acs.jproteome.6b01003

2016

Jackson, F., Georgakopoulou, N., Kaluarachchi, M., Kyriakides, M., Andreas, N., Przysiezna, N., Hyde, M. J., Modi, N., Nicholson, J. K., Wijeyesekera, A. ORCID: https://orcid.org/0000-0001-6151-5065 and Holmes, E. (2016) Development of a pipeline for exploratory metabolic profiling of infant urine. Journal of Proteome Research, 15 (9). pp. 3432-3440. ISSN 1535-3907 doi: https://doi.org/10.1021/acs.jproteome.6b00234

Baker, L., Lanz, B., Andreola, F., Ampuero, J., Wijeyesekera, A. ORCID: https://orcid.org/0000-0001-6151-5065, Holmes, E. and Deutz, N. (2016) New technologies – new insights into the pathogenesis of hepatic encephalopathy. Metabolic Brain Disease, 31 (6). pp. 1259-1267. ISSN 1573-7365 doi: https://doi.org/10.1007/s11011-016-9906-y

2015

Andreas, N. J., Hyde, M. J., Gomez‐Romero, M., Lopez-Gonzalvez, M. A., Villaseñor, A., Wijeyesekera, A. ORCID: https://orcid.org/0000-0001-6151-5065, Barbas, C., Modi, N., Holmes, E. and Garcia-Perez, I. (2015) Multiplatform characterization of dynamic changes in breast milk during lactation. Electrophoresis, 36 (18). pp. 2269-2285. ISSN 0173-0835 doi: https://doi.org/10.1002/elps.201500011

Holmes, E., Wijeyesekera, A. ORCID: https://orcid.org/0000-0001-6151-5065, Taylor-Robinson, S. D. and Nicholson, J. K. (2015) The promise of metabolic phenotyping in gastroenterology and hepatology. Nature Reviews in Gastroenterology and Hepatology, 12 (8). pp. 458-471. ISSN 1759-5045 doi: https://doi.org/10.1038/nrgastro.2015.114

Correia, G. D., Ng, K. W., Wijeyesekera, A. ORCID: https://orcid.org/0000-0001-6151-5065, Gala-Peralta, S., Williams, R., MacCarthy-Morrogh, S., Jiménez, B., Inwald, D., Macrae, D., Frost, G., Holmes, E. and Pathan, N. (2015) Metabolic profiling of children undergoing surgery for congenital heart disease. Critical Care Medicine, 43 (7). pp. 1467-1476. ISSN 1530-0293 doi: https://doi.org/10.1097/CCM.0000000000000982

Elliott, P., Posma, J. M., Chan, Q., Garcia-Perez, I., Wijeyesekera, A. ORCID: https://orcid.org/0000-0001-6151-5065, Bictash, M., Ebbels, T. M.D., Ueshima, H., Zhao, L., van Horn, L., Daviglus, M., Stamler, J., Holmes, E. and Nicholson, J. K. (2015) Urinary metabolic signatures of human adiposity. Science Translational Medicine, 7 (285). 285ra62. ISSN 1946-6242 doi: https://doi.org/10.1126/scitranslmed.aaa5680

Amiot, A., Dona, A. C., Wijeyesekera, A. ORCID: https://orcid.org/0000-0001-6151-5065, Tournigand, C., Baumgaertner, I., Lebaleur, Y., Sobhani, I. and Holmes, E. (2015) 1H NMR spectroscopy of fecal extracts enables detection of advanced colorectal neoplasia. Journal of Proteome Research, 14 (9). pp. 3871-3881. ISSN 1535-3907 doi: https://doi.org/10.1021/acs.jproteome.5b00277

Chekmeneva, E., Correia, G., Denes, J., Gomez-Romero, M., Wijeyesekera, A. ORCID: https://orcid.org/0000-0001-6151-5065, Perenyi, D. R., Koot, Y., Boomsma, C., Want, E. J., Dixon, P. H., Macklon, N. S., Chan, Q., Takats, Z., Nicholson, J. K. and Holmes, E. (2015) Development of nanoelectrospray high resolution isotope dilution mass spectrometry for targeted quantitative analysis of urinary metabolites: application to population profiling and clinical studies. Analytical Methods, 7 (12). pp. 5122-5133. ISSN 1759-9679 doi: https://doi.org/10.1039/c5ay00850f

2014

Ladep, N. G., Dona, A. C., Lewis, M. R., Crossey, M. M. E., Lemoine, M., Okeke, E., Shimakawa, Y., Duguru, M., Njai, H. F., Fye, H. K. S., Taal, M., Chetwood, J., Kasstan, B., Khan, S. A., Garside, D. A., Wijeyesekera, A. ORCID: https://orcid.org/0000-0001-6151-5065, Thillainayagam, A. V., Banwat, E., Thursz, M. R., Nicholson, J. K., Njie, R., Holmes, E. and Taylor-Robinson, S. D. (2014) Discovery and validation of urinary metabotypes for the diagnosis of hepatocellular carcinoma in West Africans. Hepatology, 60 (4). pp. 1291-1301. ISSN 1527-3350 doi: https://doi.org/10.1002/hep.27264

Klootwijk, E. D., Reichold, M., Helip-Wooley, A., Tolaymat, A., Broeker, C., Robinette, S. L., Reinders, J., Peindl, D., Renner, K., Eberhart, K., Assmann, N., Oefner, P. J., Dettmer, K., Sterner, C., Schroeder, J., Zorger, N., Witzgall, R., Reinhold, S. W., Stanescu, H. C., Bockenhauer, D., Jaureguiberry, G., Courtneidge, H., Hall, A. M., Wijeyesekera, A. ORCID: https://orcid.org/0000-0001-6151-5065, Holmes, E., Nicholson, J. K., O'Brien, K., Bernardini, I., Krasnewich, D., Arcos-Burgos, M., Izumi, Y., Nonoguchi, H., Jia, Y., Reddy, J. K., Ilyas, M., Unwin, R. J., Gahl, W. A., Warth, R. and Kleta, R. (2014) Mistargeting of peroxisomal EHHADH and inherited renal Fanconi's syndrome. The New England Journal of Medicine, 370 (2). pp. 129-138. ISSN 1533-4406 doi: https://doi.org/10.1056/NEJMoa1307581