Number of items: 37.
2022
Poston, R. N., Chughtai, J., Ujkaj, D., Louis, H., Leake, D. S.
ORCID: https://orcid.org/0000-0002-1742-6134 and Cooper, D.
(2022)
Monocytic cell adhesion to oxidised ligands: relevance to
cardiovascular disease.
Biomedicines, 10 (12).
3083.
ISSN 2227-9059
doi: https://doi.org/10.3390/biomedicines10123083
Ojo, O. O. and Leake, D.
ORCID: https://orcid.org/0000-0002-1742-6134
(2022)
Effects of lysosomal low density lipoprotein oxidation by ferritin on macrophage function.
Free Radical Research.
GFRR-OM-2022-0211.
ISSN 1071-5762
doi: https://doi.org/10.1080/10715762.2022.2133703
2021
Ahmad, F., Mitchell, R., Houben, T., Palo, A., Yasdati, T., Parnell, A., Patel, K., Shiri-Sverdlov, R. and Leake, D.
ORCID: https://orcid.org/0000-0002-1742-6134
(2021)
Cysteamine decreases low density lipoprotein oxidation, causes regression of atherosclerosis and improves liver and muscle function in LDL receptor deficient mice.
JAHA: Journal of the American Heart Association, 10 (18).
ISSN 2047-9980
doi: https://doi.org/10.1161/JAHA.120.017524
Houben, T., Yadati, T., De Kruijf, R., Gijbels, M. J., Luiken, J., Van Zandvoort, M., Kapsokalyvas, D., Lütjohann, D., Westerterp, M., Plat, J., Leake, D.
ORCID: https://orcid.org/0000-0002-1742-6134 and Shiri-Sverdlov, R.
(2021)
Pro-inflammatory implications of 2-hydroxypropyl-β-cyclodextrin treatment.
Frontiers in Immunology, 12.
716357.
ISSN 1664-3224
doi: https://doi.org/10.3389/fimmu.2021.716357
Ojo, O. O. and Leake, D. S.
ORCID: https://orcid.org/0000-0002-1742-6134
(2021)
Vitamins E and C do not effectively inhibit low density lipoprotein oxidation by ferritin at lysosomal pH.
Free Radical Research, 55 (5).
pp. 525-534.
ISSN 1071-5762
doi: https://doi.org/10.1080/10715762.2021.1964494
2020
Alboaklah, H. K.M. and Leake, D.
ORCID: https://orcid.org/0000-0002-1742-6134
(2020)
Effect of vitamin E on low density lipoprotein oxidation at lysosomal pH.
Free Radical Research, 54 (8-9).
pp. 574-584.
ISSN 1071-5762
doi: https://doi.org/10.1080/10715762.2020.1817912
Bhatti, S. N., Leidi, A., Leake, D.
ORCID: https://orcid.org/0000-0002-1742-6134 and Li, J.-m.
ORCID: https://orcid.org/0000-0002-3294-3818
(2020)
Studying biological science does not lead to adoption of a healthy lifestyle.
Perspectives in Public Health, 140 (4).
pp. 232-239.
ISSN 1757-9139
doi: https://doi.org/10.1177/1757913919890889
2019
Wen, Y., Ahmad, F., Mohri, Z., Weinberg, P. D. and Leake, D. S.
ORCID: https://orcid.org/0000-0002-1742-6134
(2019)
Cysteamine inhibits lysosomal oxidation of low density lipoprotein in human macrophages and reduces atherosclerosis in mice.
Atherosclerosis, 291.
pp. 9-18.
ISSN 0021-9150
doi: https://doi.org/10.1016/j.atherosclerosis.2019.09.019
Ahmad, F. and Leake, D. S.
ORCID: https://orcid.org/0000-0002-1742-6134
(2019)
Lysosomal oxidation of LDL alters lysosomal pH, induces senescence and increases secretion of pro-inflammatory cytokines in human macrophages.
Journal of Lipid Research, 60.
pp. 98-110.
ISSN 1539-7262
doi: https://doi.org/10.1194/jlr.M088245
2018
Ojo, O. O. and Leake, D. S.
ORCID: https://orcid.org/0000-0002-1742-6134
(2018)
Low density lipoprotein oxidation by ferritin at lysosomal pH.
Chemistry and Physics of Lipids, 217.
pp. 51-57.
ISSN 0009-3084
doi: https://doi.org/10.1016/j.chemphyslip.2018.09.016
Palmer, C., Peri, F., Neumann, F., Ahmad, F., Leake, D. S.
ORCID: https://orcid.org/0000-0002-1742-6134 and Pirianov, G.
(2018)
The synthetic glycolipid-based TLR4 antagonist FP7 negatively regulates in vitro and in vivo haematopoietic
and non-haematopoietic vascular TLR4 signalling.
Innate Immunity, 24 (7).
pp. 411-421.
ISSN 1753-4267
doi: https://doi.org/10.1177/1753425918798904
Ahmad, F. and Leake, D.
ORCID: https://orcid.org/0000-0002-1742-6134
(2018)
Antioxidants inhibit low density lipoprotein oxidation less at lysosomal pH: a possible explanation as to why the clinical trials of antioxidants might have failed.
Chemistry and Physics of Lipids, 213.
pp. 13-24.
ISSN 0009-3084
doi: https://doi.org/10.1016/j.chemphyslip.2018.03.001
2017
Calabuig-Navarro, M. V., Jackson, K. G.
ORCID: https://orcid.org/0000-0002-0070-3203, Kemp, C. F., Leake, D. S.
ORCID: https://orcid.org/0000-0002-1742-6134, Walden, C. M., Lovegrove, J. A.
ORCID: https://orcid.org/0000-0001-7633-9455 and Minihane, A. M.
(2017)
A randomized trial and novel SPR technique identifies altered lipoprotein-LDL receptor binding as a mechanism underlying elevated LDL-cholesterol in APOE4s.
Scientific Reports, 7.
44119.
ISSN 2045-2322
doi: https://doi.org/10.1038/srep44119
2014
Gerry, A. B. and Leake, D. S.
ORCID: https://orcid.org/0000-0002-1742-6134
(2014)
Effect of low extracellular pH on NF-κB activation in macrophages.
Atherosclerosis, 233 (2).
pp. 537-544.
ISSN 0021-9150
doi: https://doi.org/10.1016/j.atherosclerosis.2014.01.014
2013
Wraith, K. S., Magwenzi, S., Aburima, A., Wen, Y., Leake, D.
ORCID: https://orcid.org/0000-0002-1742-6134 and Naseem, K. M.
(2013)
Oxidised low-density lipoproteins induce rapid platelet activation and shape change through tyrosine kinase and Rho kinase-signaling pathways.
Blood, 122 (4).
pp. 580-589.
ISSN 0006-4971
doi: https://doi.org/10.1182/blood-2013-04-491688
2012
Satchell, L. and Leake, D.
ORCID: https://orcid.org/0000-0002-1742-6134
(2012)
Oxidation of low density lipoprotein by iron at lysosomal pH: implications for atherosclerosis.
Biochemistry, 51 (18).
pp. 3767-3775.
ISSN 0006-2960
doi: https://doi.org/10.1021/bi2017975
2009
Gieseg, S. P., Leake, D. S.
ORCID: https://orcid.org/0000-0002-1742-6134, Flavall, E. M., Amit, Z., Reid, L. and Yang, Y. T.
(2009)
Macrophage antioxidant protection within atherosclerotic plaques.
Frontiers in Bioscience, 1 (14).
pp. 1230-1246.
ISSN 1093-9946
doi: https://doi.org/10.2741/3305
2008
Gomez-Ruiz, J. A., Ames, J. M. and Leake, D. S.
ORCID: https://orcid.org/0000-0002-1742-6134
(2008)
Antioxidant activity and protective effects of green and dark coffee components against human low density lipoprotein oxidation.
European Food Research and Technology, 227 (4).
pp. 1017-1024.
ISSN 1438-2377
doi: https://doi.org/10.1007/s00217-007-0815-5
Gerry, A. B. and Leake, D. S.
ORCID: https://orcid.org/0000-0002-1742-6134
(2008)
A moderate reduction in extracellular pH protects macrophages against apoptosis induced by oxidised low density lipoprotein.
Journal of Lipid Research, 49 (4).
pp. 782-789.
ISSN 1539-7262
doi: https://doi.org/10.1194/jlr.M700349-JLR200
Gerry, A. B., Satchell, L. and Leake, D. S.
ORCID: https://orcid.org/0000-0002-1742-6134
(2008)
A novel method for production of lipid hydroperoxide- or oxysterol-rich low-density lipoprotein.
Atherosclerosis, 197 (2).
pp. 579-587.
ISSN 0021-9150
doi: https://doi.org/10.1016/j.atherosclerosis.2007.08.026
2007
Kappler, M., Gerry, A. B., Brown, E., Reid, L., Leake, D. S.
ORCID: https://orcid.org/0000-0002-1742-6134 and Gieseg, S. P.
(2007)
Aqueous peroxyl radical exposure to THP-1 cells causes glutathione loss followed by protein oxidation and cell death without increased caspase-3 activity.
Biochimica Et Biophysica Acta-Molecular Cell Research, 1773 (6).
pp. 945-953.
ISSN 0167-4889
doi: https://doi.org/10.1016/j.bbamcr.2007.04.001
Wong, W. M. R., Gerry, A. B., Putt, W., Roberts, J. L., Weinberg, R. B., Humphries, S. E., Leake, D. S.
ORCID: https://orcid.org/0000-0002-1742-6134 and Talmud, P. J.
(2007)
Common variants of apolipoprotein A-IV differ in their ability to inhibit low density lipoprotein oxidation.
Atherosclerosis, 192 (2).
pp. 266-274.
ISSN 0021-9150
doi: https://doi.org/10.1016/j.atherosclerosis.2006.07.017
Gomez-Ruiz, J. A., Leake, D. S.
ORCID: https://orcid.org/0000-0002-1742-6134 and Ames, J. M.
(2007)
In vitro antioxidant activity of coffee compounds and their metabolites.
Journal of Agricultural and Food Chemistry, 55 (17).
pp. 6962-6969.
ISSN 0021-8561
doi: https://doi.org/10.1021/jf0710985
Wen, Y. and Leake, D. S.
ORCID: https://orcid.org/0000-0002-1742-6134
(2007)
Low density lipoprotein undergoes oxidation within lysosomes in cells.
Circulation Research, 100.
pp. 1337-1343.
ISSN 0009-7330
doi: https://doi.org/10.1161/CIRCRESAHA.107.151704
Horsley, E. T. M., Burkitt, M. J., Jones, C. M.
ORCID: https://orcid.org/0000-0001-7537-1509, Patterson, R. A., Harris, L. K., Moss, N. J., del Rio, J. D. and Leake, D. S.
ORCID: https://orcid.org/0000-0002-1742-6134
(2007)
Mechanism of the antioxidant to pro-oxidant switch in the behavior of dehydroascorbate during LDL oxidation by copper(II) ions.
Archives of Biochemistry and Biophysics, 465 (2).
pp. 303-314.
ISSN 0003-9861
doi: https://doi.org/10.1016/j.abb.2007.07.005
2006
Harris, L. K., Mann, G. E., Ruiz, E., Mushtaq, S. and Leake, D. S.
ORCID: https://orcid.org/0000-0002-1742-6134
(2006)
Ascorbate does not protect macrophages against apoptosis induced by oxidised low density lipoprotein.
Archives of Biochemistry and Biophysics, 455 (1).
pp. 68-76.
ISSN 0003-9861
doi: https://doi.org/10.1016/j.abb.2006.07.019
Tricon, S., Burdge, G.C., Jones, E.L., Russell, J.J., El-Khazen, S., Moretti, E., Hall, W.L., Gerry, A.B., Leake, D.S.
ORCID: https://orcid.org/0000-0002-1742-6134, Grimble, R.F., Williams, C.M., Calder, P.C. and Yaqoob, P.
ORCID: https://orcid.org/0000-0002-6716-7599
(2006)
Effects of dairy products naturally enriched with cis-9,trans-11 conjugated linoleic acid on the blood lipid profile in healthy middle-aged men.
American Journal of Clinical Nutrition, 83 (4).
pp. 744-753.
ISSN 0002-9165
Jackson, K.G.
ORCID: https://orcid.org/0000-0002-0070-3203, Maitin, V., Leake, D.S.
ORCID: https://orcid.org/0000-0002-1742-6134, Yaqoob, P.
ORCID: https://orcid.org/0000-0002-6716-7599 and Williams, C.M.
(2006)
Saturated fat-induced changes in S-f 60-400 particle composition reduces uptake of LDL by HepG2 cells.
Journal of Lipid Research, 47 (2).
pp. 393-403.
ISSN 0022-2275
doi: https://doi.org/10.1194/jlr.M500382-JLR200
2005
Anwar, A. A., Li, F. Y. L., Leake, D. S.
ORCID: https://orcid.org/0000-0002-1742-6134, Ishii, T., Mann, G. E. and Siow, R. C. M.
(2005)
Induction of heme oxygenase 1 by moderately oxidized low-density lipoproteins in human vascular smooth muscle cells: role of mitogen-activated protein kinases and Nrf2.
Free Radical Biology and Medicine, 39 (2).
pp. 227-236.
ISSN 0891-5849
doi: https://doi.org/10.1016/j.freeradbiomed.2005.03.012
2004
Anwar, A. A., Leake, D. S.
ORCID: https://orcid.org/0000-0002-1742-6134 and Siow, R. C. M.
(2004)
MAPK pathways mediate induction of heme oxygenase-1 and glutathione by moderately oxidized low density lipoproteins in vascular smooth muscle cells.
Free Radical Biology and Medicine, 36.
S44-S44.
ISSN 0891-5849
Ishii, T., Itoh, K., Ruiz, E., Leake, D. S.
ORCID: https://orcid.org/0000-0002-1742-6134, Unoki, H., Yamamoto, M. and Mann, G. E.
(2004)
Role of Nrf2 in the regulation of CD36 and stress protein expression in murine macrophages - Activation by oxidatively modified LDL and 4-hydroxynonenal.
Circulation Research, 94 (5).
pp. 609-616.
ISSN 0009-7330
doi: https://doi.org/10.1161/01.res.0000119171.44657.45
2003
Kavanagh, I.C., Symes, C.E., Renaudin, P., Nova, E., Mesa, M.D., Boukouvalas, G., Leake, D.S.
ORCID: https://orcid.org/0000-0002-1742-6134 and Yaqoob, P.
ORCID: https://orcid.org/0000-0002-6716-7599
(2003)
Degree of oxidation of low density lipoprotein affects expression of CD36 and PPAR gamma, but not cytokine production, by human monocyte-macrophages.
Atherosclerosis, 168 (2).
pp. 271-282.
ISSN 0021-9150
doi: https://doi.org/10.1016/s0021-9150(03)00148-5
Patterson, R. A., Lamb, D. J. and Leake, D. S.
ORCID: https://orcid.org/0000-0002-1742-6134
(2003)
Mechanisms by which cysteine can inhibit or promote the oxidation of low density lipoprotein by copper.
Atherosclerosis, 169 (1).
pp. 87-94.
ISSN 0021-9150
doi: https://doi.org/10.1016/s0021-9150(03)00154-0
Talbot, R. M., del Rio, J. D., Leake, D. S.
ORCID: https://orcid.org/0000-0002-1742-6134 and Weinberg, P. D.
(2003)
Oxidation affects the flow-induced aggregation of low density lipoprotein and its inhibition by albumin.
Biochimica Et Biophysica Acta-Molecular and Cell Biology of Lipids, 1634 (1-2).
pp. 24-29.
ISSN 1388-1981
doi: https://doi.org/10.1016/j.bbalip.2003.08.002
Patterson, R. A., Horsley, E. T. M. and Leake, D. S.
ORCID: https://orcid.org/0000-0002-1742-6134
(2003)
Prooxidant and antioxidant properties of human serum ultrafiltrates toward LDL: important role of uric acid.
Journal of Lipid Research, 44 (3).
pp. 512-521.
ISSN 0022-2275
doi: https://doi.org/10.1194/jlr.M200407-JLR200
2002
Alderman, C. J. J., Bunyard, P. R., Chain, B. M., Foreman, J. C., Leake, D.
ORCID: https://orcid.org/0000-0002-1742-6134 and Katz, D. R.
(2002)
Effects of oxidised low density lipoprotein on dendritic cells: a possible immunoregulatory component of the atherogenic micro-environment?
Cardiovascular Research, 55 (4).
pp. 806-819.
ISSN 0008-6363
doi: https://doi.org/10.1016/S0008-6363(02)00447-9
Leigh-Firbank, E. C., Minihane, A. M., Leake, D. S.
ORCID: https://orcid.org/0000-0002-1742-6134, Wright, J. W., Murphy, M. C., Griffin, B. A. and Williams, C. M.
(2002)
Eicosapentaenoic acid and docosahexaenoic acid from fish oils: differential associations with lipid responses.
British Journal of Nutrition, 87.
pp. 435-445.
ISSN 0007-1145
doi: https://doi.org/10.1079/BJN2002556
This list was generated on Sat Aug 31 23:11:40 2024 UTC.