Number of items: 177.
2024
Oderberg, D. 
ORCID: https://orcid.org/0000-0001-9585-0515, Hill, J., Austin, C., Bojak, I. ORCID: https://orcid.org/0000-0003-1765-3502, Cinotti, F. ORCID: https://orcid.org/0000-0003-2921-0901 and Gibbins, J. ORCID: https://orcid.org/0000-0002-0372-5352
(2024)
Biological mistake theory and the question of function.
Philosophy of Science.
ISSN 1539-767X
(In Press)
Bozbas, E., Zhou, R., Soyama, S., Allen-Redpath, K., Mitchell, J. L., Fisk, H. L., Calder, P. C., Jones, C. ORCID: https://orcid.org/0000-0001-7537-1509, Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352, Fischer, R., Hester, S. and Yaqoob, P. ORCID: https://orcid.org/0000-0002-6716-7599
(2024)
Dietary n-3 polyunsaturated fatty acids alter the number, fatty acid profile and coagulatory activity of circulating and platelet-derived extracellular vesicles: a randomized, controlled crossover trial.
American Journal of Clinical Nutrition, 119 (5).
pp. 1175-1186.
ISSN 1938-3207
doi: https://doi.org/10.1016/j.ajcnut.2024.03.008
Provenzale, I., Solari, F. A., Schonichen, C., Brouns, S. L.N., Fernandez, D. I., Kuijpers, M. J.E., Van der Meijden, P. E.J., Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352, Sickman, A., Jones, C. ORCID: https://orcid.org/0000-0001-7537-1509 and Heemskerk, J. W.M.
(2024)
Endothelium-mediated regulation of platelet activation: involvement of multiple protein kinases.
FASEB Journal, 38 (4).
e23468.
ISSN 0892-6638
doi: https://doi.org/10.1096/fj.202300360RR
Authi, K. S., Khan, S., Gibbins, J. ORCID: https://orcid.org/0000-0002-0372-5352 and Brain, S. D.
(2024)
Evidence that Inositol-1,4,5-trisphosphate-3-kinase and Inositol-1,3,4,5-tetrakisphosphate are negative regulators of platelet function.
Research and Practice in Thrombosis and Haemostasis.
ISSN 2475-0379
(In Press)
2023
Provenzale, I., De Simone, I., Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352, Heemskerk, J. W. M., van der Meijden, P. E. J. and Jones, C. I. ORCID: https://orcid.org/0000-0001-7537-1509
(2023)
Regulation of glycoprotein VI-dependent platelet activation and thrombus formation by heparan sulfate proteoglycan perlecan.
International Journal of Molecular Sciences, 24 (17).
13352.
ISSN 1422-0067
doi: https://doi.org/10.3390/ijms241713352
AlOuda, S. K., Sasikumar, P., AlThunayan, T., Alaajam, F., Khan, S., Sahli, K. A., Abohassan, M. S., Pollitt, A. ORCID: https://orcid.org/0000-0001-8706-5154, Jung, S. M. and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352
(2023)
Role of heat shock protein 47 in platelet glycoprotein VI dimerisation and signaling.
Research and Practice in Thrombosis and Haemostasis, 7 (6).
102177.
ISSN 2475-0379
doi: https://doi.org/10.1016/j.rpth.2023.102177
Mitchell, J. L., Dunster, J. L. ORCID: https://orcid.org/0000-0001-8986-4902, Kriek, N., Unsworth, A. J., Sage, T., Mohammed, Y. M. M., De Simone, I., Taylor, K. A. ORCID: https://orcid.org/0000-0002-4599-7727, Bye, A. P. ORCID: https://orcid.org/0000-0002-2061-2253, Ólafsson, G., Brunton, M., Mark, S., Dymott, L. D., Whyte, A., Ruparelia, N., Mckenna, C., Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 and Jones, C. I. ORCID: https://orcid.org/0000-0001-7537-1509
(2023)
The rate of platelet activation determines thrombus size and structure at arterial shear.
Journal of Thrombosis and Haemostasis, 21 (8).
pp. 2248-2259.
ISSN 1538-7836
doi: https://doi.org/10.1016/j.jtha.2023.03.044
Kuravi, S. J., Ahmed, N. S., Taylor, K. A. ORCID: https://orcid.org/0000-0002-4599-7727, Capes, E. M., Bye, A. ORCID: https://orcid.org/0000-0002-2061-2253, Unsworth, A. J., Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 and Pugh, N.
(2023)
Delineating zinc influx mechanisms during platelet activation.
International Journal of Molecular Sciences, 24 (14).
11689.
ISSN 1422-0067
doi: https://doi.org/10.3390/ijms241411689
Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352
(2023)
Adding fuel to the flames in pre-eclampsia: the platelet connection.
Journal of Thrombosis and Haemostasis, 21 (7).
pp. 1750-1752.
ISSN 1538-7933
doi: https://doi.org/10.1016/j.jtha.2023.03.031
Mitchell, J. L., Little, G., Bye, A. P. ORCID: https://orcid.org/0000-0002-2061-2253, Gaspar, R. S., Unsworth, A. J., Kriek, N., Sage, T., Stainer, A., Sangowawa, I., Morrow, G. B., Bastos, R. N., Shapiro, S., Desborough, M. J. R., Curry, N., Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352, Whyte, C. S., Mutch, N. J. and Jones, C. I. ORCID: https://orcid.org/0000-0001-7537-1509
(2023)
Platelet factor XIII-A regulates platelet function and promotes clot retraction and stability.
Research and Practice in Thrombosis and Haemostasis, 7 (5).
100200.
ISSN 2475-0379
doi: https://doi.org/10.1016/j.rpth.2023.100200
Ranjbar, J., Njoroge, W. ORCID: https://orcid.org/0009-0003-1365-5129, Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352, Roach, P. ORCID: https://orcid.org/0000-0003-4135-9733, Yang, Y. ORCID: https://orcid.org/0000-0002-1362-6040 and Harper, A. G. S. ORCID: https://orcid.org/0000-0003-2413-4823
(2023)
Developing biomimetic hydrogels of the arterial wall as a prothrombotic substrate for in vitro human thrombosis models.
Gels, 9 (6).
477.
ISSN 2310-2861
doi: https://doi.org/10.3390/gels9060477
Cheung, H. Y. F., Zou, J., Tantiwong, C., Fernandez, D. I., Huang, J., Ahrends, R., Roest, M., Cavill, R., Gibbins, J. ORCID: https://orcid.org/0000-0002-0372-5352 and Heemskerk, J. W. M.
(2023)
High-throughput assessment identifying major platelet Ca2+ entry pathways via tyrosine kinase-linked and G protein-coupled receptors.
Cell Calcium, 112.
102738.
ISSN 0143-4160
doi: https://doi.org/10.1016/j.ceca.2023.102738
Bye, A. P. ORCID: https://orcid.org/0000-0002-2061-2253, Kriek, N., Sage, T., Rawlings, S. J., Prodger, C., Kesavan, M., Lees, C., Booth, S., Cowen, L. G., Shefferd, K., Desborough, M. J., Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 and Eyre, T. A.
(2023)
Pirtobrutinib results in reversible platelet dysfunction compared to ibrutinib and acalabrutinib.
Haematologica, 108 (5).
ISSN 1592-8721
doi: https://doi.org/10.3324/haematol.2022.281402
Nelson, M. R., Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 and Dunster, J. L. ORCID: https://orcid.org/0000-0001-8986-4902
(2023)
Platelet-driven routes to chaos in a model of hepatitis.
Chaos, Solitons & Fractals, 170.
113338.
ISSN 1873-2887
doi: https://doi.org/10.1016/j.chaos.2023.113338
De Simone, I., Baaten, C. C. F. M. J., Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352, Ten Cate, H., Heemskerk, J. W. M., Jones, C. I. ORCID: https://orcid.org/0000-0001-7537-1509 and van der Meijden, P. E. J.
(2023)
Repeated platelet activation and the potential of previously
activated platelets to contribute to thrombus formation.
Journal of Thrombosis and Haemostasis, 21 (5).
pp. 1289-1306.
ISSN 1538-7933
doi: https://doi.org/10.1016/j.jtha.2023.01.006
Thienel, M., Müller-Reif, J. B., Zhang, Z., Ehreiser, V., Huth, J., Shchurovska, K., Kilani, B., Schweizer, L., Geyer, P. E., Zweibel, M., Novotny, J., Lüsebrink, E., Little, G., Orban, M., Nicolai, L., El Nemr, S., Titova, A., Spannagl, M., Kindberg, J., Evans, A. L., Mach, O., Vogel, M., Tiedt, S., Ormanns, S., Kessler, B., Dueck, A., Friebe, A., Godsk Jørgensen, P., Majzoub-Altweck, M., Blutke, A., Polzin, A., Stark, K., Kääb, S., Maier, D., Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352, Limper, U., Frobert, O., Mann, M., Massberg, S. and Petzold, T.
(2023)
Immobility-associated thromboprotection is conserved across mammalian species from bear to human.
Science, 380 (6641).
pp. 178-187.
ISSN 1095-9203
doi: https://doi.org/10.1126/science.abo5044
Tantiwong, C., Dunster, J. L. ORCID: https://orcid.org/0000-0001-8986-4902, Cavill, R., Tomlinson, M. G., Wierling, C., Heemskerk, J. W. M. and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352
(2023)
An agent-based approach for modelling and simulation of glycoprotein VI receptor diffusion, localisation and dimerisation in platelet lipid rafts.
Scientific Reports, 13.
3906.
ISSN 2045-2322
doi: https://doi.org/10.1038/s41598-023-30884-6
Dunster, J. L. ORCID: https://orcid.org/0000-0001-8986-4902, Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 and Nelson, M. R.
(2023)
Exploring the constituent mechanisms of hepatitis: a dynamical systems approach.
Mathematical Medicine and Biology: A Journal of the IMA, 40 (1).
pp. 24-48.
ISSN 1477-8599
doi: https://doi.org/10.1093/imammb/dqac013
Oderberg, D. ORCID: https://orcid.org/0000-0001-9585-0515, Hill, J., Austin, C., Bojak, I. ORCID: https://orcid.org/0000-0003-1765-3502, Cinotti, F. ORCID: https://orcid.org/0000-0003-2921-0901 and Gibbins, J. ORCID: https://orcid.org/0000-0002-0372-5352
(2023)
Biological mistakes: what they are and what they mean for the experimental biologist.
British Journal for the Philosophy of Science.
ISSN 1464-3537
doi: https://doi.org/10.1086/724444
(In Press)
Mitchell, J. L., Khan, D., Rana, R. H., Kriek, N., Unsworth, A. J., Sage, T., Bye, A. P. ORCID: https://orcid.org/0000-0002-2061-2253, Laffan, M., Shapiro, S., Thakurta, A., Grech, H., Ramasamy, K. and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352
(2023)
Multiple myeloma and its treatment contribute to increased platelet reactivity.
Platelets, 34 (1).
2264940.
ISSN 1369-1635
doi: https://doi.org/10.1080/09537104.2023.2264940
2022
Pycraft Hughes, M., Kruchek, E. J., Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352, Griffiths, O. V., Abdal, B. and Labeed, F. H.
(2022)
The platelet electrome: evidence for a role in regulation of function and surface interaction.
Bioelectricity, 4 (3).
pp. 153-159.
ISSN 2576-3113
doi: https://doi.org/10.1089/bioe.2021.0044
Kriek, N., Nock, S. H., Sage, T., Khalifa, B., Bye, A. P. ORCID: https://orcid.org/0000-0002-2061-2253, Mitchell, J. L., Thomson, S., McLaughlin, M. G., Jones, S., Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 and Unsworth, A. J. ORCID: https://orcid.org/0000-0003-3809-5984
(2022)
Cucurbitacins elicit anti-platelet activity via perturbation of the cytoskeleton and integrin function.
Thrombosis and Haemostasis, 122 (07).
pp. 1115-1129.
ISSN 0340-6245
doi: https://doi.org/10.1055/a-1788-5322
Downes, K., Zhao, X., Gleadall, N. S., Antanavicius, N., McKinney, H., Kempster, C., Batista, J., Thomas, P. L., Cooper, M., Michael, J. V., Kreuzhuber, R., Wedderburn, K., Waller, K., Varney, B., Kriek, N., Ashford, S. E., Stirrups, K. E., Dunster, J. L. ORCID: https://orcid.org/0000-0001-8986-4902, McKenzie, S. E., Ouwehand, W. H., Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352, Yang, J., Astle, W. J. and Ma, P.
(2022)
G protein-coupled receptor kinase 5 regulates thrombin signaling in platelets via PAR-1.
Blood Advances, 6 (7).
pp. 2319-2330.
ISSN 2473-9529
doi: https://doi.org/10.1182/bloodadvances.2021005453
Kempster, C., Butler, G., Kuznecova, E., Taylor, K. A. ORCID: https://orcid.org/0000-0002-4599-7727, Kriek, N., Little, G., Sowa, M. A., Sage, T., Johnson, L. J. ORCID: https://orcid.org/0000-0002-0006-1511, Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 and Pollitt, A. Y. ORCID: https://orcid.org/0000-0001-8706-5154
(2022)
Fully automated platelet differential interference contrast image analysis via deep learning.
Scientific Reports, 12.
4614.
ISSN 2045-2322
doi: https://doi.org/10.1038/s41598-022-08613-2
Hill, J., Oderberg, D. ORCID: https://orcid.org/0000-0001-9585-0515, Gibbins, J. ORCID: https://orcid.org/0000-0002-0372-5352 and Bojak, I. ORCID: https://orcid.org/0000-0003-1765-3502
(2022)
Mistake-making: a theoretical framework for generating research questions in biology, with illustrative application to blood clotting.
Quarterly Review of Biology, 97 (1).
ISSN 0033-5770
doi: https://doi.org/10.1086/718736
Waller, A. K., Birch, K., Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 and Clarke, S. R.
(2022)
Activation of Human Platelets by Staphylococcus aureus
Secreted Protease Staphopain A.
Pathogens, 11 (11).
1237.
ISSN 2076-0817
doi: https://doi.org/10.3390/pathogens11111237
De Simone, I., Baaten, C. C. F. M. J., Jandrot-Perrus, M., Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352, ten Cate, H., Heemskerk, J. W. M., Jones, C. I. ORCID: https://orcid.org/0000-0001-7537-1509 and van der Meijden, P. E. J.
(2022)
Coagulation factor XIIIa and activated protein C activate platelets via GPVI and PAR1.
International Journal of Molecular Sciences, 23 (18).
10203.
ISSN 1422-0067
doi: https://doi.org/10.3390/ijms231810203
Wright, J. R., Jones, S., Parvathy, S., Kaczmarek, L. K., Forsythe, I., Farndale, R. W., Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 and Mahaut-Smith, M. P.
(2022)
The voltage-gated K+ channel Kv1.3 modulates platelet motility and α2β1 integrin-dependent adhesion to collagen.
Platelets, 33 (3).
pp. 451-461.
ISSN 0953-7104
doi: https://doi.org/10.1080/09537104.2021.1942818
2021
Dunster, J. ORCID: https://orcid.org/0000-0001-8986-4902, Bye, A. ORCID: https://orcid.org/0000-0002-2061-2253, Kriek, N., Sage, T., Mitchell, J., Kempster, C., Batista, J., KcKinney, H., Thomas, P., Jones, C. ORCID: https://orcid.org/0000-0001-7537-1509, Downes, K., Unsworth, A. and Gibbins, J. ORCID: https://orcid.org/0000-0002-0372-5352
(2021)
Multi-parameter phenotyping of platelet reactivity for stratification of human cohorts.
Blood Advances, 5 (20).
pp. 4017-4030.
ISSN 2473-9529
doi: https://doi.org/10.1182/bloodadvances.2020003261
Simoes Gaspar, R. and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352
(2021)
Thiol isomerases orchestrate thrombosis and haemostasis.
Antioxidants & Redox Signaling, 35 (13).
ISSN 1523-0864
doi: https://doi.org/10.1089/ars.2021.0086
Bye, A. P. ORCID: https://orcid.org/0000-0002-2061-2253, Hoepel, W., Mitchell, J. L., Jegouic, S. M., Loureiro, S. ORCID: https://orcid.org/0009-0000-8886-6893, Sage, T., Vidarsson, G., Nouta, J., Wuhrer, M., de Taeye, S. W., van Gils, M., Kriek, N., Cooper, N., Jones, I. ORCID: https://orcid.org/0000-0002-7738-2516, den Dunnen, J. and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352
(2021)
Aberrant glycosylation of anti-SARS-CoV-2 spike IgG is a pro-thrombotic stimulus for platelets.
Blood, 138 (16).
pp. 1481-1489.
ISSN 0006-4971
doi: https://doi.org/10.1182/blood.2021011871
Gaspar, R. S., Mansilla, S., Vieira, V. A., da Silva, L. B., Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352, Castro, L., Trostchansky, A. and de A. Paes, A. M.
(2021)
The protein disulphide isomerase inhibitor CxxCpep modulates
oxidative burst and mitochondrial function in platelets.
Free Radical Biology and Medicine, 172.
pp. 668-674.
ISSN 0891-5849
doi: https://doi.org/10.1016/j.freeradbiomed.2021.07.011
Unsworth, A. J., Bye, A. P. ORCID: https://orcid.org/0000-0002-2061-2253, Sage, T., Gaspar, R. S., Eaton, N., Drew, C., Stainer, A., Kriek, N., Volberding, P. J., Hutchinson, J. L., Riley, R., Jones, S., Mundell, S. J., Cui, W., Falet, H. and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352
(2021)
Anti-platelet properties of Pim kinase inhibition is mediated through disruption of thromboxane A2 receptor signalling.
Haematologica, 106 (7).
ISSN 1592-8721
doi: https://doi.org/10.3324/haematol.2019.223529
Taylor, K. A. ORCID: https://orcid.org/0000-0002-4599-7727, Little, G. and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352
(2021)
Mind the gap: connexins and pannexins in platelet function.
Platelets, 32 (7).
pp. 888-894.
ISSN 0953-7104
doi: https://doi.org/10.1080/09537104.2021.1902971
Simoes Gaspar, R., Sage, T., Little, G., Kriek, N., Pula, G. and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352
(2021)
Protein disulphide isomerase and NADPH oxidase 1 cooperate
to control platelet function and are associated with cardiometabolic disease risk factors.
Antioxidants, 10 (3).
497.
ISSN 2076-3921
doi: https://doi.org/10.3390/antiox10030497
Gaspar, R. S., Ferreira, P., Mitchell, J. L., Pula, G. and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352
(2021)
Platelet-derived extracellular vesicles express NADPH oxidase-1 (Nox-1), generate superoxide and modulate platelet function.
Free Radical Biology and Medicine, 165.
pp. 395-400.
ISSN 0891-5849
doi: https://doi.org/10.1016/j.freeradbiomed.2021.01.051
Sahli, K. A., Flora, G. D., Sasikumar, P., Maghrabi, A. H., Holbrook, L., AlOuda, S. K., Elgheznawy, A., Sage, T., Stainer, A. R., Adiyaman, R., AboHassan, M., Crescente, M., Kriek, N., Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517, Bye, A. P. ORCID: https://orcid.org/0000-0002-2061-2253, Unsworth, A. J., Jones, C. I. ORCID: https://orcid.org/0000-0001-7537-1509, McGuffin, L. J. ORCID: https://orcid.org/0000-0003-4501-4767 and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352
(2021)
Structural, functional and mechanistic insights uncover the fundamental role of orphan connexin-62 in platelets.
Blood, 137 (6).
pp. 830-843.
ISSN 0006-4971
doi: https://doi.org/10.1182/blood.2019004575
Holbrook, L.-M., Keeton, S. J., Sasikumar, P., Nock, S., Gelzinis, J., Brunt, E., Ryan, S., Pantos, M. M., Verbetsky, C. A., Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 and Kennedy, D. R.
(2021)
Zafirlukast is a broad-spectrum thiol isomerase inhibitor that inhibits thrombosis without altering bleeding times.
British Journal of Pharmacology, 178 (3).
pp. 550-563.
ISSN 1476-5381
doi: https://doi.org/10.1111/bph.15291
Cai, H., Sasikumar, P., Little, G., Bihan, D., Hamaia, S. W., Zhou, A., Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 and Farndale, R. W.
(2021)
Identification of HSP47 binding site on native collagen and
its implications on the development of HSP47 inhibitors.
Biomolecules, 11 (7).
983.
ISSN 2218-273X
doi: https://doi.org/10.3390/biom11070983
Majeed, K. R., Al-Fahad, D., Jalood, H. H., Hantosh, H. A., Ali, M. K., Sakthivel, S., Williams, H. F., Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352, Patel, K., Baksh, M. F. ORCID: https://orcid.org/0000-0003-3107-8815 and Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517
(2021)
RhD blood type significantly influences susceptibility to contract COVID-19 among a study population in Iraq.
F1000Research.
ISSN 2046-1402
doi: https://doi.org/10.12688/f1000research.27777.1
Dunster, J. ORCID: https://orcid.org/0000-0001-8986-4902, Mitchell, J., Mohammed, Y., Taylor, K. ORCID: https://orcid.org/0000-0002-4599-7727, Gibbins, J. ORCID: https://orcid.org/0000-0002-0372-5352 and Jones, C. ORCID: https://orcid.org/0000-0001-7537-1509
(2021)
Kinetx: a combined flow cytometry assay and analysis software framework to quantitatively measure and categorize platelet activation in real-time.
Journal of Visualized Experiments, 176.
e62947.
ISSN 1940-087X
doi: https://doi.org/10.3791/62947
Gaspar, R. S., Unsworth, A. J., Al-Dibouni, A., Bye, A. P., Sage, T., Stewart, M., Cox, R. D., Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352, Sellayah, D. and Hughes, C. ORCID: https://orcid.org/0000-0002-9790-5820
(2021)
Maternal and offspring high-fat diet leads to platelet hyperactivation in male mice offspring.
Scientific Reports, 11.
1473.
ISSN 2045-2322
doi: https://doi.org/10.1038/s41598-020-80373-3
Soriano Jerez, E. M., Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 and Hughes, C. E. ORCID: https://orcid.org/0000-0002-9790-5820
(2021)
Targeting platelet inhibition receptors for novel therapies: PECAM-1 and G6b-B.
Platelets, 32 (6).
pp. 761-769.
ISSN 0953-7104
doi: https://doi.org/10.1080/09537104.2021.1882668
2020
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Control of platelet CLEC-2-mediated activation by receptor clustering and tyrosine kinase signalling.
Biophysical Journal, 118 (11).
ISSN 0006-3495
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lopes Pires, M. E., Ahmed, N. S., Vara, D., Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352, Pula, G. and Pugh, N.
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Myricetin, the main flavonoid in Syzygium cumini leaf, is a novel inhibitor of platelet thiol isomerases PDI and ERp5.
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A model of the PI cycle reveals the regulating roles of lipid-binding proteins and pitfalls of using mosaic biological data.
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Non-genomic effects of the Pregnane X Receptor negatively regulate platelet functions, thrombosis and haemostasis.
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Gradient-dependent inhibition of stimulatory signaling from platelet G protein-coupled receptors.
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Quercetin and its methylated metabolites possess anti-thrombotic properties that interact with aspirin to enhance its anti-platelet effects.
TH Open, 3 (3).
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Cobimetinib and trametinib inhibit platelet MEK but do not cause platelet dysfunction.
Platelets, 30 (6).
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Salamah, M. F., Ravishankar, D., Vaiyapuri, R., Moraes, L. A., Patel, K., Perretti, M., Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 and Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517
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The formyl peptide fMLF primes platelet activation and augments thrombus formation.
Journal of Thrombosis and Haemostasis, 17 (7).
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ISSN 1538-7836
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NADPH oxidase 2 (NOX2): a key target of oxidative stress-mediated platelet activation and thrombosis.
Trends in Cardiovascular Medicine, 28 (7).
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Talin is a substrate for SUMOylation in migrating cancer cells.
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Platelets and Megakaryocytes. Volume 4, Advanced Protocols and Perspectives.
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Move along, nothing to see here: Btk inhibitors stop platelets sticking to plaques.
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(2018)
Connexins and pannexins in vascular function and disease.
International Journal of Molecular Sciences, 19 (6).
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The chaperone protein HSP47: a platelet collagen binding protein that contributes to thrombosis and haemostasis.
Journal of Thrombosis and Haemostasis, 16 (5).
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(2018)
Non-genomic effects of nuclear receptors: insights from the anucleate platelet.
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A humanized monoclonal antibody that inhibits platelet-surface ERp72 reveals a role for ERp72 in thrombosis.
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Mathematical techniques for understanding platelet regulation and the development of new pharmacological approaches.
In: Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 and Mahaut-Smith, M. (eds.)
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Screening and high-throughput platelet assays.
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The endogenous antimicrobial cathelicidin LL37 induces platelet activation and augments thrombus formation.
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Severe platelet dysfunction in NHL patients receiving ibrutinib is absent in patients receiving acalabrutinib.
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RXR ligands negatively regulate thrombosis and hemostasis.
Arteriosclerosis Thrombosis and Vascular Biology, 37 (5).
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PPARγ agonists negatively regulate αIIbβ3 integrin outside-in signalling and platelet function through upregulation of protein kinase A activity.
Journal of Thrombosis and Haemostasis, 15 (2).
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Lopes Pires, M. E., Clarke, S. R., Marcondes, S. and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352
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Lipopolysaccharide potentiates platelet responses via toll-like receptor 4-stimulated Akt-Erk-PLA2 signalling.
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Ruthenium-conjugated chrysin analogues modulate platelet activity, thrombus formation and haemostasis with enhanced efficacy.
Scientific Reports, 7.
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Farnesoid X Receptor and its ligands inhibit the function of platelets.
Arteriosclerosis Thrombosis and Vascular Biology, 36 (12).
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(2016)
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Arteriosclerosis Thrombosis and Vascular Biology, 36 (6).
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Journal of Thrombosis and Haemostasis, 14 (5).
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Platelets stop us leaking.
Blood, 127 (12).
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A high-density immunoblotting methodology for quantification of total protein levels and phosphorylation modifications.
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GRID and docking analyses reveal a molecular basis for flavonoid inhibition of src-family kinase activity.
Journal of Nutritional Biochemistry, 26 (11).
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Ibrutinib inhibits platelet integrin αIIbβ3 outside-in signaling and thrombus stability but not adhesion to collagen.
Arteriosclerosis Thrombosis and Vascular Biology, 35 (11).
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Regulation of early steps of GPVI signal transduction by phosphatases: a systems biology approach.
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Syncytiotrophoblast extracellular vesicles from pre-eclampsia placentas differentially affect platelet function.
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Pharmacological actions of nobiletin in the modulation of platelet function.
British Journal of Pharmacology, 172 (16).
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ISSN 0007-1188
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Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517, Sunagar, K., Gibbins, J. ORCID: https://orcid.org/0000-0002-0372-5352, Jackson, T. N. W., Reeks, T. and Fry, B. G.
(2015)
Kallikrein enzymes.
In: Fry, B. (ed.)
Venomous reptiles and their toxins: evolution, pathophysiology and biodiscovery.
Oxford University Press, New York, pp. 267-280.
ISBN 9780199309399
Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517, Flora, G. D. and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352
(2015)
Gap junctions and connexin hemichannels in the regulation of haemostasis and thrombosis.
Biochemical Society Transactions, 43 (3).
pp. 489-494.
ISSN 1470-8752
doi: https://doi.org/10.1042/BST20150055
Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517, Sage, T., Rana, R. H., Schenk, M. P., Ali, M. S., Unsworth, A. J., Jones, C. I. ORCID: https://orcid.org/0000-0001-7537-1509, Stainer, A. R., Kriek, N. K., Moraes, L. A. and Gibbins, J. ORCID: https://orcid.org/0000-0002-0372-5352
(2015)
EphB2 regulates contact-dependent and independent signalling to control platelet function.
Blood, 125 (4).
pp. 720-730.
ISSN 0006-4971
doi: https://doi.org/10.1182/blood-2014-06-585083
2014
Jones, C. I. ORCID: https://orcid.org/0000-0001-7537-1509, Sage, T., Moraes, L. A., Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517, Hussain, U., Tucker, K. L., Barrett, N. E. ORCID: https://orcid.org/0000-0001-9123-1100 and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352
(2014)
Platelet endothelial cell adhesion molecule-1 inhibits platelet response to thrombin and von Willebrand factor by regulating the internalization of glycoprotein Ib via AKT/glycogen synthase kinase-3/dynamin and integrin αIIbβ3.
Arteriosclerosis Thrombosis and Vascular Biology, 34 (9).
pp. 1968-1976.
ISSN 1079-5642
doi: https://doi.org/10.1161/ATVBAHA.114.304097
Jones, C. I. ORCID: https://orcid.org/0000-0001-7537-1509, Tucker, K. L., Sasikumar, P., Sage, T., Kaiser, W. J., Moore, C., Emerson, M. and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352
(2014)
Integrin-linked kinase regulates the rate of platelet activation and is essential for the formation of stable thrombi.
Journal of Thrombosis and Haemostasis, 12 (8).
pp. 1342-1352.
ISSN 1538-7933
doi: https://doi.org/10.1111/jth.12620
Taylor, L., Vasudevan, S. R., Jones, C. I. ORCID: https://orcid.org/0000-0001-7537-1509, Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352, Churchill, G. C., Campbell, R. D. and Coxon, C. H.
(2014)
Discovery of novel GPVI receptor antagonists by structure-based repurposing.
PLoS ONE, 9 (6).
e101209.
ISSN 1932-6203
doi: https://doi.org/10.1371/journal.pone.0101209
Dannoura, A., Giraldo, A., Pereira, I., Gibbins, J. ORCID: https://orcid.org/0000-0002-0372-5352, Dash, P., Bicknell, K. ORCID: https://orcid.org/0000-0002-5888-1424 and Brooks, G.
(2014)
Ibuprofen inhibits migration and proliferation of human coronary artery smooth muscle cells by inducing a differentiated phenotype: role of peroxisome proliferator-activated receptor y.
Journal of Pharmacy and Pharmacology, 66 (6).
pp. 779-792.
ISSN 0022-3573
doi: https://doi.org/10.1111/jphp.12203
Ambily, A., Kaiser, W. J., Pierro, C., Chamberlain, E. V., Li, Z., Jones, C. I. ORCID: https://orcid.org/0000-0001-7537-1509, Kassouf, N., Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 and Authi, K. S.
(2014)
The role of plasma membrane STIM1 and Ca(2+)entry in platelet aggregation. STIM1 binds to novel proteins in human platelets.
Cellular Signalling, 26 (3).
pp. 502-511.
ISSN 0898-6568
doi: https://doi.org/10.1016/j.cellsig.2013.11.025
2013
Waller, A. K., Sage, T., Kumar, C., Carr, T., Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 and Clarke, S. R.
(2013)
Staphylococcus aureus lipoteichoic acid inhibits platelet activation and thrombus formation via the Paf receptor.
Journal of Infectious Diseases, 208 (12).
pp. 2046-2057.
ISSN 1537-6613
doi: https://doi.org/10.1093/infdis/jit398
Wright, B., Spencer, J. P. E. ORCID: https://orcid.org/0000-0003-2931-7274, Lovegrove, J. A. ORCID: https://orcid.org/0000-0001-7633-9455 and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352
(2013)
Flavonoid inhibitory pharmacodynamics on platelet function in physiological environments.
Food & Function, 4 (12).
pp. 1803-1810.
ISSN 2042-650X
doi: https://doi.org/10.1039/C3FO60272A
Wright, B., Tindall, M. J., Lovegrove, J. A. ORCID: https://orcid.org/0000-0001-7633-9455 and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352
(2013)
Investigating flavonoids as molecular templates for the design of small-molecule inhibitors of cell signaling.
Journal of Food Science, 78 (12).
N1921-N1928.
ISSN 1750-3841
doi: https://doi.org/10.1111/1750-3841.12293
Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517, Ali, M. S., Moraes, L. A., Sage, T., Lewis, K. R., Jones, C. I. ORCID: https://orcid.org/0000-0001-7537-1509 and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352
(2013)
Tangeretin regulates platelet function through inhibition of phosphoinositide 3-Kinase and cyclic nucleotide signaling.
Arteriosclerosis Thrombosis and Vascular Biology, 33 (12).
pp. 2740-2749.
ISSN 1079-5642
doi: https://doi.org/10.1161/ATVBAHA.113.301988
Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517, Vaiyapuri, R., Ashokan, R., Ramasamy, K., Nattamaisundar, K., Jeyaraj, A., Chandran, V., Gajjeraman, P., Baksh, M. F. ORCID: https://orcid.org/0000-0003-3107-8815, Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 and Hutchinson, E. G.
(2013)
Snakebite and its socio-economic impact on the rural population of Tamil Nadu, India.
PLoS ONE, 8 (11).
e80090.
ISSN 1932-6203
doi: https://doi.org/10.1371/journal.pone.0080090
Gibbins, J. ORCID: https://orcid.org/0000-0002-0372-5352
(2013)
Platelets using proteins creatively.
Blood, 122 (22).
pp. 3553-3554.
ISSN 0006-4971
doi: https://doi.org/10.1182/blood-2013-09-527663
Moraes, L. A., Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517, Sasikumar, P., Ali, M. S., Kriek, N. K., Sage, T. and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352
(2013)
Antithrombotic actions of statins involve PECAM-1 signalling.
Blood, 122 (18).
pp. 3188-3196.
ISSN 0006-4971
doi: https://doi.org/10.1182/blood-2013-04-491845
Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517, Moraes, L. A., Sage, T., Ali, M. S., Lewis, K. R., Mayhaut-Smith, M. P., Oviedo-Orta, E., Simon, A. M. and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352
(2013)
Connexin40 regulates platelet function.
Nature Communications, 4.
pp. 2564-2572.
ISSN 2041-1723
doi: https://doi.org/10.1038/ncomms3564
Kim, K., Hahm, E., Li, J., Holbrook, L.-M., Sasikumar, P., Stanley, R. G., Ushio-Fukai, M., Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 and Cho, J.
(2013)
Platelet protein disulfide isomerase is required for thrombus formation but not essential for hemostasis in mice.
Blood, 122 (6).
pp. 1052-1061.
ISSN 0006-4971
doi: https://doi.org/10.1182/blood-2013-03-492504
Wright, B., Stanley, R. G., Kaiser, W. J. and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352
(2013)
The integration of proteomics and systems approaches to map regulatory mechanisms underpinning platelet function.
Proteomics, Clinical Applications, 7 (1-2).
pp. 144-154.
ISSN 1862-8354
doi: https://doi.org/10.1002/prca.201200095
Wright, B., Spencer, J. P. E. ORCID: https://orcid.org/0000-0003-2931-7274, Lovegrove, J. A. ORCID: https://orcid.org/0000-0001-7633-9455 and Gibbins, J. ORCID: https://orcid.org/0000-0002-0372-5352
(2013)
Insights into dietary flavonoids as molecular templates for the design of anti-platelet drugs.
Cardiovascular Research, 97 (1).
pp. 13-22.
ISSN 0008-6363
doi: https://doi.org/10.1093/cvr/cvs304
2012
Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517, Thiyagarajan, N., Hutchinson, E. G. and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352
(2012)
Sequence and phylogenetic analysis of viper venom
serine proteases.
Bioinformation, 8 (16).
pp. 763-772.
ISSN 0973-2063
Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517, Hutchinson, E. G., Ali, M. S., Dannoura, A., Stanley, R. G., Harrison, R. A., Bicknell, A. B. and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352
(2012)
Rhinocetin, a venom-derived integrin-specific antagonist inhibits collagen-induced platelet and endothelial cell functions.
The Journal of Biological Chemistry, 287 (31).
pp. 26235-26244.
ISSN 1083-351X
doi: https://doi.org/10.1074/jbc.M112.381483
Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517, Jones, C. I. ORCID: https://orcid.org/0000-0001-7537-1509, Sasikumar, P., Moraes, L. A., Munger, S. J., Wright, J. R., Ali, M. S., Sage, T., Kaiser, W. J., Tucker, K. L., Stain, C. J., Bye, A. P., Jones, S., Oviedo-Orta, E., Simon, A. M., Mahaut-Smith, M. P. and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352
(2012)
Gap junctions and connexin hemichannels underpin hemostasis and thrombosis.
Circulation, 125 (20).
pp. 2479-2491.
ISSN 0009-7322
doi: https://doi.org/10.1161/CIRCULATIONAHA.112.101246
Gibbins, J. ORCID: https://orcid.org/0000-0002-0372-5352
(2012)
JAMming the signals.
Blood, 119 (14).
pp. 3197-3198.
ISSN 1528-0020
doi: https://doi.org/10.1182/blood-2012-02-409060
Holbrook, L.-M., Sasikumar, P., Stanley, R. G., Simmonds, A. D., Bicknell, A. B. and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352
(2012)
The platelet-surface thiol isomerase enzyme ERp57 modulates platelet function.
Journal of Thrombosis and Haemostasis, 10 (2).
pp. 278-288.
ISSN 1538-7933
doi: https://doi.org/10.1111/j.1538-7836.2011.04593.x
Coxon, C. H., Lewis, A. M., Sadler, A. J., Vasudevan, S. R., Thomas, A., Dundas, K. A., Taylor, L., Campbell, R.D., Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352, Churchill, G. C. and Tucker, K. L.
(2012)
NAADP regulates human platelet function.
Biochemical Journal, 441 (1).
pp. 435-442.
ISSN 0264-6021
doi: https://doi.org/10.1042/BJ20111175
Mitchell, H. L., Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352, Griffin, B. A., Lovegrove, J. A. ORCID: https://orcid.org/0000-0001-7633-9455, Stowell, J. D. and Foot, E.
(2012)
Food and Health Forum meeting - nutritional approaches to cardiovascular health: workshop report.
Nutrition Bulletin, 37 (3).
pp. 270-284.
ISSN 1471-9827
doi: https://doi.org/10.1111/j.1467-3010.2012.01984.x
Jones, C. I. ORCID: https://orcid.org/0000-0001-7537-1509, Moraes, L. A. and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352
(2012)
Regulation of platelet biology by platelet endothelial cell adhesion molecule-1.
Platelets, 23 (5).
pp. 331-335.
ISSN 1369-1635
doi: https://doi.org/10.3109/09537104.2011.626091
Bertling, A., Niemann, S., Hussain, M., Holbrook, L., Stanley, R. G., Brodde, M. F., Pohl, S., Schifferdecker, T., Roth, J., Jurk, K., Müller, A., Lahav, J., Peters, G., Heilmann, C., Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 and Kehrel, B. E.
(2012)
Staphylococcal extracellular adherence protein induces platelet activation by stimulation of thiol isomerases.
Arteriosclerosis Thrombosis and Vascular Biology, 32.
pp. 1979-1990.
ISSN 1079-5642
doi: https://doi.org/10.1161/ATVBAHA.112.246249
2011
Wright, B., Stanley, R. G., Kaiser, W. J., Mills, D. J. and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352
(2011)
Analysis of protein networks in resting and collagen receptor (GPVI)-stimulated platelet sub-proteomes.
Proteomics, 11 (23).
pp. 4588-4592.
ISSN 1615-9853
doi: https://doi.org/10.1002/pmic.201100410
Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517, Wagstaff, S. C., Harrison, R. A., Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 and Hutchinson, G.
(2011)
Evolutionary analysis of novel serine proteases in the
venom gland transcriptome of Bitis gabonica rhinoceros.
PLoS ONE, 6 (6).
e21532.
ISSN 1932-6203
doi: https://doi.org/10.1371/journal.pone.0021532
Spyridon, M., Moraes, L. A., Jones, C. I. ORCID: https://orcid.org/0000-0001-7537-1509, Sage, T., Sasikumar, P., Bucci, G. and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352
(2011)
LXR as a novel antithrombotic target.
Blood, 117 (21).
pp. 5751-5761.
ISSN 1528-0020
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Stanley, R., Tucker, K., Barrett, N. E. ORCID: https://orcid.org/0000-0001-9123-1100 and Gibbins, J. ORCID: https://orcid.org/0000-0002-0372-5352
(2011)
Platelets and their role in thrombotic and cardiovascular disease: the impact of proteomic analysis.
In: Garcia, A. and Senis, Y. (eds.)
Platelet Proteomics: Principles, Analysis and Applications.
Mass Spectrometry .
Wiley, pp. 3-26.
ISBN 9780470463376
Tucker, K. L., Sage, T. and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352
(2011)
Clot retraction.
In: Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 and Mahaut-Smith, M. P. (eds.)
Platelets and Megakaryocytes. vol. 3, Additional Protocols and Perspectives.
Methods in Molecular Biology, vol. 788.
Humana Press, pp. 101-108.
ISBN 9781617793066
Jones, C. I. ORCID: https://orcid.org/0000-0001-7537-1509, Barrett, N. E. ORCID: https://orcid.org/0000-0001-9123-1100, Moraes, L. A., Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 and Jackson, D. E.
(2011)
Endogenous inhibitory mechanisms and the regulation platelet function.
In: Gibbins, J. ORCID: https://orcid.org/0000-0002-0372-5352 and Mahaut-Smith, M. (eds.)
Platelets and Megakaryocytes. vol. 3, Additional Protocols and Perspectives.
Methods in Molecular Biology, vol. 788.
Humana Press, pp. 341-366.
ISBN 9781617793066
2010
Moraes, L. A., Barrett, N. E. ORCID: https://orcid.org/0000-0001-9123-1100, Jones, C. ORCID: https://orcid.org/0000-0001-7537-1509, Holbrook, L. M., Spyridon, M., Sage, T., Newman, D. K. and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352
(2010)
Platelet endothelial cell adhesion molecule-1 regulates collagen-stimulated platelet function by modulating the association of phosphatidylinositol 3-kinase with Grb-2-associated binding protein-1 and linker for activation of T cells.
Journal of Thrombosis and Haemostasis, 8 (11).
pp. 2530-2541.
ISSN 1538-7933
doi: https://doi.org/10.1111/j.1538-7836.2010.04025.x
Glen, A., Evans, C. A., Gan, C. S., Cross, S. S., Hamdy, F. C., Gibbins, J. ORCID: https://orcid.org/0000-0002-0372-5352, Lippitt, J., Eaton, C. L., Noirel, J., Wright, P. C. and Rehman, I.
(2010)
Eight-plex iTRAQ analysis of variant metastatic human prostate cancer cells identifies candidate biomarkers of progression: an exploratory study.
The Prostate, 70 (12).
pp. 1313-1332.
ISSN 1097-0045
doi: https://doi.org/10.1002/pros.21167
Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517, Wagstaff, S. C., Watson, K. A. ORCID: https://orcid.org/0000-0002-9987-8539, Harrison, R. A., Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 and Hutchinson, E. G.
(2010)
Purification and functional characterisation of rhiminopeptidase A, a novel aminopeptidase from the venom of Bitis gabonica rhinoceros.
PLoS Neglected Tropical Diseases, 4 (8).
e796.
ISSN 1935-2735
doi: https://doi.org/10.1371/journal.pntd.0000796
Wright, B., Gibson, T., Spencer, J. ORCID: https://orcid.org/0000-0003-2931-7274, Lovegrove, J. A. ORCID: https://orcid.org/0000-0001-7633-9455 and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352
(2010)
Platelet-mediated metabolism of the common dietary flavonoid, quercetin.
PLoS ONE, 5 (3).
e9673.
ISSN 1932-6203
doi: https://doi.org/10.1371/journal.pone.0009673
Moraes, L. A., Spyridon, M., Kaiser, W. J., Jones, C. ORCID: https://orcid.org/0000-0001-7537-1509, Sage, T., Atherton, R. E. and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352
(2010)
Non-genomic effects of PPARgamma ligands: inhibition of GPVI-stimulated platelet activation.
Journal of Thrombosis and Haemostasis, 8 (3).
pp. 577-587.
ISSN 1538-7933
doi: https://doi.org/10.1111/j.1538-7836.2009.03732.x
Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517, Harrison, R. A., Bicknell, A., Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 and Hutchinson, E. G.
(2010)
Purification and functional characterisation of Rhinocerase, a novel serine protease from the venom of Bitis gabonica rhinoceros.
PLoS ONE, 5 (3).
e9687.
ISSN 1932-6203
doi: https://doi.org/10.1371/journal.pone.0009687
Wright, B., Moraes, L. A., Kemp, C. F., Mullen, W., Crozier, A., Lovegrove, J. A. ORCID: https://orcid.org/0000-0001-7633-9455 and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352
(2010)
A structural basis for the inhibition of collagen-stimulated platelet function by quercetin and structurally related flavonoids.
British Journal of Pharmacology, 159.
pp. 1312-1325.
ISSN 1476-5381
doi: https://doi.org/10.1111/j.1476-5381.2009.00632.x
Holbrook, L. M., Watkins, N. A., Simmonds, A. D., Jones, C. ORCID: https://orcid.org/0000-0001-7537-1509, Ouwehand, W. H. and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352
(2010)
Platelets release novel thiol isomerase enzymes which are recruited to the cell surface following activation.
British Journal of Haematology, 148 (4).
pp. 627-637.
ISSN 0007-1048
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Jones, C. I. ORCID: https://orcid.org/0000-0001-7537-1509, Garner, S. F., Moraes, L. A., Kaiser, W. J., Rankin, A., Bloodomics Consortium, , Ouwehand, W. H., Goodall, A. H. and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352
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PECAM-1 expression and activity negatively regulate multiple platelet signaling pathways.
FEBS Letters, 583 (22).
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Tucker, K. L., Kaiser, W. J., Bergeron, A. L., Hu, H. B., Dong, J. F., Tan, T. H. and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352
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Proteomic analysis of resting and thrombin-stimulated platelets reveals the translocation and functional relevance of HIP-55 in platelets.
Proteomics, 9 (18).
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Tweaking the gain on platelet regulation: The tachykinin connection.
Atherosclerosis, 206 (1).
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A functional proteomic method for the enrichment of peripheral membrane proteins reveals the collagen binding protein Hsp47 is exposed on the surface of activated human platelets.
Journal of Proteome Research, 8 (6).
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Barrett, N. E. ORCID: https://orcid.org/0000-0001-9123-1100, Holbrook, L., Jones, S., Kaiser, W. J., Moraes, L. A., Rana, R., Sage, T., Stanley, R. G., Tucker, K. L., Wright, B. and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352
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Future innovations in anti-platelet therapies.
British Journal of Pharmacology, 154 (5).
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Peripheral tachykinins and the neurokinin receptor NK1 are required for platelet thrombus formation.
Blood, 111 (2).
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A dual role for integrin-linked kinase in platelets: regulating integrin function and alpha-granule secretion.
Blood, 112 (12).
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ISSN 0006-4971
doi: https://doi.org/10.1182/blood-2008-03-148502
Jones, S. and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352
(2008)
The neurokinin 1 receptor: a potential new target for anti-platelet therapy?
Current Opinion in Pharmacology, 8 (2).
pp. 114-119.
ISSN 1471-4892
doi: https://doi.org/10.1016/j.coph.2008.01.004
2007
Guerrero, J. A., Navarro-Nunez, L., Lozano, M. L., Martinez, C., Vicente, V., Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 and Rivera, J.
(2007)
Flavonoids inhibit the platelet TxA(2) signalling pathway and antagonize TxA(2) receptors (TP) in platelets and smooth muscle cells.
British Journal of Clinical Pharmacology, 64 (2).
pp. 133-144.
ISSN 0306-5251
doi: https://doi.org/10.1111/j.1365-2125.2007.02881.x
Gumireddy, K., Sun, F. X., Klein-Szanto, A. J., Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352, Gimotty, P. A., Saunders, A. J., Schultz, P. G. and Huang, Q. H.
(2007)
In vivo selection for metastasis promoting genes in the mouse.
Proceedings of the National Academy of Sciences of the United States of America, 104 (16).
pp. 6696-6701.
ISSN 0027-8424
doi: https://doi.org/10.1073/pnas.0701145104
Moraes, L. A., Bishop-Bailey, D. and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352
(2007)
Non-genomic signalling of the retinoic X receptor through inhibition of Gq signalling in human platelets.
Heart, 93 (11).
pp. 371-374.
ISSN 1355-6037
Moraes, L. A., Swales, K. E., Wray, J. A., Damazo, A., Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352, Warner, T. D. and Bishop-Bailey, D.
(2007)
Nongenomic signaling of the retinoid X receptor through binding and inhibiting Gq in human platelets.
Blood, 109 (9).
pp. 3741-3744.
ISSN 0006-4971
doi: https://doi.org/10.1182/blood-2006-05-022566
2006
Hubbard, G. P., Wolffram, S., de Vos, R., Bovy, A., Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 and Lovegrove, J. A. ORCID: https://orcid.org/0000-0001-7633-9455
(2006)
Ingestion of onion soup high in quercetin inhibits platelet aggregation and essential components of the collagen-stimulated platelet activation pathway in man: a pilot study.
British Journal of Nutrition, 96 (3).
pp. 482-488.
ISSN 0007-1145
Jordan, P. A. and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352
(2006)
Extracellular disulfide exchange and the regulation of cellular function.
Antioxidants & Redox Signaling, 8 (3-4).
pp. 312-324.
ISSN 1523-0864
Falati, S., Patil, S., Gross, P. L., Stapleton, M., Merrill-Skoloff, G., Barrett, N. E. ORCID: https://orcid.org/0000-0001-9123-1100, Pixton, K. L., Weiler, H., Cooley, B., Newman, D. K., Newman, P. J., Furie, B. C., Furie, B. and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352
(2006)
Platelet PECAM-1 inhibits thrombus formation in vivo.
Blood, 107 (2).
pp. 535-541.
ISSN 0006-4971
doi: https://doi.org/10.1182/blood-2005-04-1512
Patel, B., Sharifi, M., Milward, A. D., Oberprieler, N. G., Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352, Parkin, S. and Naseem, K. M.
(2006)
Platelet nitric oxide synthase is activated by tyrosine dephosphorylation: possible role for SHP-1 phosphatase.
Journal of Thrombosis and Haemostasis, 4 (11).
pp. 2423-2432.
ISSN 1538-7933
doi: https://doi.org/10.1111/j.1538-7836.2006.02160.x
2005
Jordan, P. A., Stevens, J. M., Hubbard, G. P., Barrett, N. E. ORCID: https://orcid.org/0000-0001-9123-1100, Sage, T., Authi, K. S. and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352
(2005)
A role for the thiol isomerase. protein ERP5 in platelet function.
Blood, 105 (4).
pp. 1500-1507.
ISSN 0006-4971
doi: https://doi.org/10.1182/blood-2004-02-0608
2004
Hubbard, G.P., Wolffram, S., Lovegrove, J.A. ORCID: https://orcid.org/0000-0001-7633-9455 and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352
(2004)
Ingestion of quercetin inhibits platelet aggregation and essential components of the collagen-stimulated platelet activation pathway in humans.
Journal of Thrombosis and Haemostasis, 2 (12).
pp. 2138-2145.
ISSN 1538-7933
doi: https://doi.org/10.1111/j.1538-7836.2004.01067.x
Coffey, M.J., Jarvis, G.E., Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352, Coles, B., Barrett, N.E. ORCID: https://orcid.org/0000-0001-9123-1100, Wylie, O.R.E. and O'Donnell, V.B.
(2004)
Platelet 12-lipoxygenase activation via glycoprotein VI:
involvement of multiple signaling pathways in agonist control of H(P)ETE synthesis.
Circulation Research, 94 (12).
pp. 1598-1605.
ISSN 0009-7330
doi: https://doi.org/10.1161/01.RES.0000132281.78948.65
Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352
(2004)
Platelet adhesion signalling and the regulation of thrombus formation.
Journal of Cell Science, 117 (16).
pp. 3415-3425.
ISSN 0021-9533
doi: https://doi.org/10.1242/jcs.01325
Jones, M. L., Craik, J. D., Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 and Poole, A. W.
(2004)
Regulation of SHP-1 tyrosine phosphatase in human platelets by serine phosphorylation at its C terminus.
The Journal of Biological Chemistry, 279 (39).
pp. 40475-40483.
ISSN 1083-351X
doi: https://doi.org/10.1074/jbc.M402970200
Batuwangala, T., Leduc, M., Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352, Bon, C. and Jones, E. Y.
(2004)
Structure of the snake-venom toxin convulxin.
Acta Crystallographica Section D- Biological Crystallography, 60 (1).
pp. 46-53.
ISSN 0907-4449
doi: https://doi.org/10.1107/s0907444903021620
Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352
(2004)
Study of tyrosine kinases and protein tyrosine phosphorylation.
Methods in Molecular Biology, 273.
pp. 153-168.
ISSN 1064-3745
doi: https://doi.org/10.1385/1-59259-783-1:153
Graham, G. J., Stevens, J. M., Page, N. M., Grant, A. D., Brain, S. D., Lowry, P. J. and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352
(2004)
Tachykinins regulate the function of platelets.
Blood, 104 (4).
pp. 1058-1065.
ISSN 0006-4971
doi: https://doi.org/10.1182/blood-2003-11-3979
Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352
(2004)
Techniques for analysis of proteins by SDS-polyacrylamide gel electrophoresis and Western blotting.
Methods in Molecular Biology, 273.
pp. 139-152.
ISSN 1064-3745
doi: https://doi.org/10.1385/1592597831
Stevens, J. M., Jordan, P. A., Sage, T. and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352
(2004)
The regulation of integrin-linked kinase in human platelets: evidence for involvement in the regulation of integrin alpha(2)beta(1).
Journal of Thrombosis and Haemostasis, 2 (8).
pp. 1443-1452.
ISSN 1538-7933
doi: https://doi.org/10.1111/j.1538-7836.2004.00870.x
2003
Polanowska-Grabowska, R., Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 and Gear, A. R. L.
(2003)
Platelet adhesion to collagen and collagen-related peptide under flow. Roles of the alpha(2)beta(1) integrin, GPVI, and Src tyrosine kinases.
Arteriosclerosis Thrombosis and Vascular Biology, 23 (10).
pp. 1934-1940.
ISSN 1079-5642
doi: 01.ATV.0000086937.46974.70v1
Hubbard, G.P., Stevens, J.M., Cicmil, M., Sage, T., Jordan, P.A., Williams, C.M., Lovegrove, J.A. ORCID: https://orcid.org/0000-0001-7633-9455 and Gibbins, J.M. ORCID: https://orcid.org/0000-0002-0372-5352
(2003)
Quercetin inhibits collagen-stimulated platelet activation through inhibition of multiple components of the glycoprotein VI signaling pathway.
Journal of Thrombosis and Haemostasis, 1 (5).
pp. 1079-1088.
ISSN 1538-7933
doi: https://doi.org/10.1046/j.1538-7836.2003.00212.x
Barry, F. A., Graham, G. J., Fry, M. J. and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352
(2003)
Regulation of glycogen synthase kinase 3 in human platelets: a possible role in platelet function?
FEBS Letters, 553 (1-2).
pp. 173-178.
ISSN 0014-5793
doi: https://doi.org/10.1016/s0014-5793(03)01015-9
Hubbard, G. P., Wolffram, S., Lovegrove, J. A. ORCID: https://orcid.org/0000-0001-7633-9455 and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352
(2003)
The role of polyphenolic compounds in the diet as inhibitors of platelet function.
Proceedings of the Nutrition Society, 62 (2).
pp. 469-478.
ISSN 0029-6651
doi: https://doi.org/10.1079/pns2003253
2002
Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352
(2002)
The negative regulation of platelet function: extending the role of the ITIM.
Trends in Cardiovascular Medicine, 12 (5).
pp. 213-219.
ISSN 1050-1738
Barry, F. A. and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352
(2002)
Protein kinase B is regulated in platelets by the collagen receptor glycoprotein VI.
The Journal of Biological Chemistry, 277 (15).
pp. 12874-12878.
ISSN 1083-351X
doi: https://doi.org/10.1074/jbc.M200482200
Cicmil, M., Thomas, J., Leduc, M., Bon, C. and Gibbins, J. ORCID: https://orcid.org/0000-0002-0372-5352
(2002)
Platelet endothelial cell adhesion molecule-1 signaling inhibits the activation of human platelets.
Blood, 99 (1).
pp. 137-144.
ISSN 0006-4971
doi: https://doi.org/10.1182/blood.V99.1.137
2000
Berlanga, O., Bobe, R., Becker, M., Murphy, G., Leduc, M., Bon, C., Barry, F., Gibbins, J. ORCID: https://orcid.org/0000-0002-0372-5352, Garcia, P., Frampton, J. and Watson, S. P.
(2000)
Expression of the collagen receptor glycoprotein VI during megakaryocyte differentiation.
Blood, 96 (8).
pp. 2740-2745.
ISSN 0006-4971
Cicmil, M., Thomas, J. M., Sage, T., Barry, F. A., Leduc, M., Bon, C. and Gibbins, J. ORCID: https://orcid.org/0000-0002-0372-5352
(2000)
Collagen, convulxin, and thrombin stimulate aggregation-independent tyrosine phosphorylation of CD31 in platelets. Evidence for the involvement of Src family kinases.
The Journal of biological chemistry, 275 (35).
pp. 27339-27347.
ISSN 0021-9258
doi: https://doi.org/10.1074/jbc.M003196200
1999
Mountford, J. C., Melford, S. K., Bunce, C. M., Gibbins, J. ORCID: https://orcid.org/0000-0002-0372-5352 and Watson, S. P.
(1999)
Collagen or collagen-related peptide cause (Ca2+)i elevation and increased tyrosine phosphorylation in human megakaryocytes.
Thrombosis and haemostasis, 82 (3).
pp. 1153-1159.
ISSN 0340-6245
1998
Gibbins, J. ORCID: https://orcid.org/0000-0002-0372-5352, Briddon, S., Shutes, A., van Vugt, M. J., van de Winkel, J. G., Saito, T. and Watson, S. P.
(1998)
The p85 subunit of phosphatidylinositol 3-kinase associates with the Fc receptor gamma-chain and linker for activitor of T cells (LAT) in platelets stimulated by collagen and convulxin.
The Journal of biological chemistry, 273 (51).
pp. 34437-34443.
ISSN 0021-9258
Watson, S. P. and Gibbins, J. ORCID: https://orcid.org/0000-0002-0372-5352
(1998)
Collagen receptor signalling in platelets: extending the role of the ITAM.
Immunology today, 19 (6).
pp. 260-264.
ISSN 0167-5699
1997
Gibbins, J. ORCID: https://orcid.org/0000-0002-0372-5352, Okuma, M., Farndale, R., Barnes, M. and Watson, S. P.
(1997)
Glycoprotein VI is the collagen receptor in platelets which underlies tyrosine phosphorylation of the Fc receptor gamma-chain.
FEBS letters, 413 (2).
pp. 255-259.
ISSN 0014-5793
Poole, A., Gibbins, J. ORCID: https://orcid.org/0000-0002-0372-5352, Turner, M., van Vugt, M. J., van de Winkel, J. G., Saito, T., Tybulewicz, V. L. and Watson, S. P.
(1997)
The Fc receptor gamma-chain and the tyrosine kinase Syk are essential for activation of mouse platelets by collagen.
The EMBO journal, 16 (9).
pp. 2333-2341.
ISSN 0261-4189
Asselin, J., Gibbins, J. ORCID: https://orcid.org/0000-0002-0372-5352, Achison, M., Lee, Y. H., Morton, L. F., Farndale, R. W., Barnes, M. J. and Watson, S. P.
(1997)
A collagen-like peptide stimulates tyrosine phosphorylation of syk and phospholipase C gamma2 in platelets independent of the integrin alpha2beta1.
Blood, 89 (4).
pp. 1235-1242.
ISSN 0006-4971
1996
Gibbins, J. ORCID: https://orcid.org/0000-0002-0372-5352, Woods, R. and Lowry, P.
(1996)
Affinity purification of 61- and 65-kDa rat brain corticotropin-releasing factor receptors and receptor-associated G proteins.
The international journal of biochemistry & cell biology, 28 (9).
pp. 1017-1029.
ISSN 1357-2725
Gibbins, J. ORCID: https://orcid.org/0000-0002-0372-5352, Asselin, J., Farndale, R., Barnes, M., Law, C. L. and Watson, S. P.
(1996)
Tyrosine phosphorylation of the Fc receptor gamma-chain in collagen-stimulated platelets.
The Journal of biological chemistry, 271 (30).
pp. 18095-18099.
ISSN 0021-9258
Robinson, A., Gibbins, J. ORCID: https://orcid.org/0000-0002-0372-5352, Rodríguez-Liñares, B., Finan, P. M., Wilson, L., Kellie, S., Findell, P. and Watson, S. P.
(1996)
Characterization of Grb2-binding proteins in human platelets activated by Fc gamma RIIA cross-linking.
Blood, 88 (2).
pp. 522-530.
ISSN 0006-4971
Woods, R., David, J., Baigent, S., Gibbins, J. ORCID: https://orcid.org/0000-0002-0372-5352 and Lowry, P.
(1996)
Elevated levels of corticotrophin-releasing factor binding protein in the blood of patients suffering from arthritis and septicaemia and the presence of novel ligands in synovial fluid.
British journal of rheumatology, 35 (2).
pp. 120-124.
ISSN 0263-7103
1994
Woods, R., Kennedy, K. M., Gibbins, J. ORCID: https://orcid.org/0000-0002-0372-5352, Behan, D., Vale, W. and Lowry, P.
(1994)
Corticotropin-releasing factor binding protein dimerizes after association with ligand.
Endocrinology, 135 (2).
pp. 768-773.
ISSN 0013-7227
This list was generated on Fri Nov 8 21:12:42 2024 UTC.
