2023

Pozza, M. D., Mesdom, P., Abdullrahman, A., Prieto Otoya, T. D., Arnoux, P., Frochot, C. ORCID: https://orcid.org/0000-0002-7659-3864, Niogret, G., Saubaméa, B., Burckel, P., Hall, J. P. ORCID: https://orcid.org/0000-0003-3716-4378, Hollenstein, M. ORCID: https://orcid.org/0000-0003-0263-9206, Cardin, C. J. ORCID: https://orcid.org/0000-0002-2556-9995 and Gasser, G. ORCID: https://orcid.org/0000-0002-4244-5097 (2023) Increasing the π-expansive ligands in ruthenium(II) polypyridyl complexes: synthesis, characterization, and biological evaluation for photodynamic therapy applications. Inorganic Chemistry, 62 (45). pp. 18510-18523. ISSN 1520-510X doi: https://doi.org/10.1021/acs.inorgchem.3c02606

2022

Dalla Pozza, M., Abdullrahman, A., Cardin, C. J. ORCID: https://orcid.org/0000-0002-2556-9995, Gasser, G. and Hall, J. P. ORCID: https://orcid.org/0000-0003-3716-4378 (2022) Three’s a crowd – stabilisation, structure, and applications of DNA triplexes. Chemical Science (35). pp. 10193-10215. ISSN 2041-6539 doi: https://doi.org/10.1039/d2sc01793h

Baker, Y. R., Thorpe, C., Chen, J., Poller, L. M., Cox, L., Kumar, P., Lim, W. F., Lie, L., McClorey, G., Epple, S., Singleton, D., McDonough, M. A., Hardwick, J. S., Christensen, K. E., Wood, M. J. A., Hall, J. P. ORCID: https://orcid.org/0000-0003-3716-4378, El-Sagheer, A. H. and Brown, T. (2022) An LNA-amide modification that enhances the cell uptake and activity of phosphorothioate exon-skipping oligonucleotides. Nature Communications, 13. pp. 1-13. ISSN 2041-1723 doi: https://doi.org/10.1038/s41467-022-31636-2

McQuaid, K. T. ORCID: https://orcid.org/0000-0002-3222-5584, Takahashi, S., Baumgaertner, L., Cardin, D. J., Paterson, N. G., Hall, J. P. ORCID: https://orcid.org/0000-0003-3716-4378, Sugimoto, N. and Cardin, C. J. ORCID: https://orcid.org/0000-0002-2556-9995 (2022) Ruthenium polypyridyl complex bound to a unimolecular chair-form G-quadruplex. Journal of the American Chemical Society, 144 (13). pp. 5956-5964. ISSN 0002-7863 doi: https://doi.org/10.1021/jacs.2c00178

Allman, S., Cordy, J., Hall, J. ORCID: https://orcid.org/0000-0003-3716-4378, Kleanthous, V. and Lander, L. (2022) Exploring the perception of additional information content in 360° 3D VR video for teaching and learning. Virtual Worlds, 1 (1). pp. 1-17. ISSN 2813-2084 doi: https://doi.org/10.3390/virtualworlds1010001

2020

Hall, J. P. ORCID: https://orcid.org/0000-0003-3716-4378 and Allman, S. A. (2020) Blending virtual reality with traditional approaches to encourage engagement with core chemistry concepts relevant to an undergraduate pharmacy curriculum. Pharmacy Education, 20 (1). pp. 365-374. ISSN 1477-2701 doi: https://doi.org/10.46542/pe.2020.201.365374

Baptista, F. R., Devereux, S. J., Gurung, S. P., Hall, J. P. ORCID: https://orcid.org/0000-0003-3716-4378, Sazanovich, I. V., Towrie, M., Cardin, C. J. ORCID: https://orcid.org/0000-0002-2556-9995, Brazier, J. A. ORCID: https://orcid.org/0000-0002-4952-584X, Kelly, J. M. and Quinn, S. J. (2020) The influence of loops on the binding of the [Ru(phen)2dppz]2+ light-switch compound to i-motif DNA structures revealed by time-resolved spectroscopy. Chemical Communications, 56 (67). pp. 9703-9706. ISSN 1359-7345 doi: https://doi.org/10.1039/D0CC03702H

2019

Pages, B. J., Gurung, S. P., McQuaid, K. ORCID: https://orcid.org/0000-0002-3222-5584, Hall, J. P. ORCID: https://orcid.org/0000-0003-3716-4378, Cardin, C. J. ORCID: https://orcid.org/0000-0002-2556-9995 and Brazier, J. A. ORCID: https://orcid.org/0000-0002-4952-584X (2019) Stabilization of long-looped i-motif DNA by polypyridyl ruthenium complexes. Frontiers in Chemistry, 7. 744. ISSN 2296-2646 doi: https://doi.org/10.3389/fchem.2019.00744

Conlon, P. F., Eguaogie, O., Wilson, J., Sweet, J. S. T., Steinhögl, J., Englert, K., Hancox, O. G. A., Law, C. J., Allman, S. A., Tucker, J. H. R., Hall, J. P. ORCID: https://orcid.org/0000-0003-3716-4378 and Vyle, J. S. (2019) Solid-phase synthesis and structural characterisation of phosphoroselenolate-modified DNA: a backbone analogue which does not impose conformational bias and facilitates SAD X-ray crystallography. Chemical Science, 10 (47). pp. 10948-10957. ISSN 1478-6524 doi: https://doi.org/10.1039/C9SC04098F

McQuaid, K., Abell, H., Gurung, S. P., Allan, D. R., Winter, G., Sorensen, T., Cardin, D. J., Brazier, J. A. ORCID: https://orcid.org/0000-0002-4952-584X, Cardin, C. J. ORCID: https://orcid.org/0000-0002-2556-9995 and Hall, J. P. ORCID: https://orcid.org/0000-0003-3716-4378 (2019) Structural studies reveal the enantiospecific recognition of a DNA G-quadruplex by a ruthenium polypyridyl complex. Angewandte Chemie International Edition, 58 (29). pp. 9881-9885. ISSN 1433-7851 doi: https://doi.org/10.1002/anie.201814502

McQuaid, K. ORCID: https://orcid.org/0000-0002-3222-5584, Hall, J. P. ORCID: https://orcid.org/0000-0003-3716-4378, Baumgaertner, L., Cardin, D. J. and Cardin, C. J. ORCID: https://orcid.org/0000-0002-2556-9995 (2019) Three thymine/adenine binding modes of the ruthenium complex Λ-[Ru (TAP)2(dppz)]2+ to the G-quadruplex forming sequence d(TAGGGTT) shown by X-ray crystallography. Chemical Communications, 55. pp. 9116-9119. ISSN 1359-7345 doi: https://doi.org/10.1039/C9CC04316K

2018

McQuaid, K., Hall, J. P. ORCID: https://orcid.org/0000-0003-3716-4378, Brazier, J. A. ORCID: https://orcid.org/0000-0002-4952-584X, Cardin, D. J. and Cardin, C. J. ORCID: https://orcid.org/0000-0002-2556-9995 (2018) X-ray crystal structures show DNA stacking advantage of terminal nitrile substitution in Ru-dppz complexes. Chemistry- A European Journal, 24 (59). pp. 15859-15867. ISSN 1521-3765 doi: https://doi.org/10.1002/chem.201803021

Cardin, C. J. ORCID: https://orcid.org/0000-0002-2556-9995 and Hall, J. P. ORCID: https://orcid.org/0000-0003-3716-4378 (2018) Structural studies of DNA-binding metal complexes of therapeutic importance. In: Waring, M. J. (ed.) DNA-targeting Molecules as Therapeutic Agents. Royal Society of Chemistry, pp. 198-227. ISBN 9781782629924 doi: https://doi.org/10.1039/9781788012928-00198

2017

Keane, P. M., Hall, J. P. ORCID: https://orcid.org/0000-0003-3716-4378, Poynton, F. E., Poulson, B. C., Gurung, S. P., Clark, I. P., Sazanovich, I. V., Towrie, M., Gunnlaugsson, T., Quinn, S. J., Cardin, C. J. ORCID: https://orcid.org/0000-0002-2556-9995 and Kelly, J. M. (2017) Inosine can increase DNA's susceptibility to photo-oxidation by a Ru(II) complex due to structural change in the minor groove. Chemistry - A European Journal, 23 (43). pp. 10344-10351. ISSN 0947-6539 doi: https://doi.org/10.1002/chem.201701447

Hall, J. P. ORCID: https://orcid.org/0000-0003-3716-4378, Gurung, S. P., Henle, J., Poidl, P., Andersson, J., Lincoln, P., Winter, G., Sorensen, T., Cardin, D. J., Brazier, J. A. ORCID: https://orcid.org/0000-0002-4952-584X and Cardin, C. J. ORCID: https://orcid.org/0000-0002-2556-9995 (2017) Guanine can direct binding specificity of Ru-dppz complexes to DNA through steric effects. Chemistry: A European Journal, 23 (21). pp. 4981-4985. ISSN 0947-6539 doi: https://doi.org/10.1002/chem.201605508

2016

Hall, J. P. ORCID: https://orcid.org/0000-0003-3716-4378, Keane, P. M., Beer, H., Buchner, K., Winter, G., Sorensen, T. L., Cardin, D. J., Brazier, J. A. ORCID: https://orcid.org/0000-0002-4952-584X and Cardin, C. J. ORCID: https://orcid.org/0000-0002-2556-9995 (2016) Delta chirality ruthenium ‘light-switch’ complexes can bind in the minor groove of DNA with five different binding modes. Nucleic Acids Research, 44 (19). pp. 9472-9482. ISSN 1362-4962 doi: https://doi.org/10.1093/nar/gkw753

Poynton, F. E., Hall, J. P. ORCID: https://orcid.org/0000-0003-3716-4378, Keane, P. M., Schwarz, C., Sazanovich, I. V., Towrie, M., Gunnlaugsson, T., Cardin, C. J. ORCID: https://orcid.org/0000-0002-2556-9995, Cardin, D. J., Quinn, S. J., Long, C. and Kelly, J. M. (2016) Direct observation by time-resolved infrared spectroscopy of the bright and the dark excited states of the [Ru(phen)2(dppz)]2+ light-switch compound in solution and when bound to DNA. Chemical Science, 7 (5). pp. 3075-3084. ISSN 1478-6524 doi: https://doi.org/10.1039/C5SC04514B

2015

Keane, P. M., Poynton, F. E., Hall, J. P. ORCID: https://orcid.org/0000-0003-3716-4378, Clark, I. P., Sazanovich, I. V., Towrie, M., Gunnlaugsson, T., Quinn, S. J., Cardin, C. J. ORCID: https://orcid.org/0000-0002-2556-9995 and Kelly, J. M. (2015) Monitoring guanine photo-oxidation by enantiomerically resolved Ru(II) dipyridophenazine complexes using inosine-substituted oligonucleotides. Faraday Discussions, 185. pp. 455-469. ISSN 1364-5498 doi: https://doi.org/10.1039/c5fd00085h

Hall, J. P. ORCID: https://orcid.org/0000-0003-3716-4378, Poynton, F. E., Keane, P. M., Gurung, S. P., Brazier, J. A. ORCID: https://orcid.org/0000-0002-4952-584X, Cardin, D. J., Winter, G., Gunnlaugsson, T., Sazanovich, I. V., Towrie, M., Cardin, C. J. ORCID: https://orcid.org/0000-0002-2556-9995, Kelly, J. M. and Quinn, S. J. (2015) Monitoring one-electron photo-oxidation of guanine in DNA crystals using ultrafast infrared spectroscopy. Nature Chemistry, 7. pp. 961-967. ISSN 1755-4330 doi: https://doi.org/10.1038/nchem.2369

Keane, P. M., Poynton, F. E., Hall, J. P. ORCID: https://orcid.org/0000-0003-3716-4378, Sazanovich, I. V., Towrie, M., Gunnlaugsson, T., Quinn, S. J., Cardin, C. J. ORCID: https://orcid.org/0000-0002-2556-9995 and Kelly, J. M. (2015) Reversal of a single base pair step controls guanine photo-oxidation by an intercalating Ru(II) dipyridophenazine complex. Angewandte Chemie-International Edition, 54 (29). pp. 8364-8368. ISSN 1433-7851 doi: https://doi.org/10.1002/anie.201502608

Keane, P. M., Poynton, F. E., Hall, J. P. ORCID: https://orcid.org/0000-0003-3716-4378, Clark, I. P., Sazanovich, I. V., Towrie, M., Gunnlaugsson, T., Quinn, S. J., Cardin, C. J. ORCID: https://orcid.org/0000-0002-2556-9995 and Kelly, J. M. (2015) Enantiomeric conformation controls rate and yield of photoinduced electron transfer in DNA sensitized by Ru(II) Dipyridophenazine complexes. Journal of Physical Chemistry Letters, 6 (4). pp. 734-738. ISSN 1948-7185 doi: https://doi.org/10.1021/jz502743q

Gurung, S. P., Schwarz, C., Hall, J. P. ORCID: https://orcid.org/0000-0003-3716-4378, Cardin, C. J. ORCID: https://orcid.org/0000-0002-2556-9995 and Brazier, J. A. ORCID: https://orcid.org/0000-0002-4952-584X (2015) The importance of loop length on the stability of i-motif structures. Chemical Communications, 51 (26). pp. 5630-5632. ISSN 1359-7345 doi: https://doi.org/10.1039/C4CC07279K

Hall, J. P. ORCID: https://orcid.org/0000-0003-3716-4378, Beer, H., Buchner, K., Cardin, D. J. and Cardin, C. J. ORCID: https://orcid.org/0000-0002-2556-9995 (2015) The structural effect of Methyl substitution on the binding of Polypyridyl Ru-dppz Complexes to DNA. Organometallics, 34 (11). pp. 2481-2486. ISSN 1520-6041 doi: https://doi.org/10.1021/om501208x

2014

Hall, J. P. ORCID: https://orcid.org/0000-0003-3716-4378, Sanchez-Weatherby, J., Alberti, C., Hurtado Quimper, C., O'Sullivan, K., Brazier, J. A. ORCID: https://orcid.org/0000-0002-4952-584X, Winter, G., Sorensen, T., Kelly, J. M., Cardin, D. J. and Cardin, C. J. ORCID: https://orcid.org/0000-0002-2556-9995 (2014) Controlled dehydration of a ruthenium complex-DNA crystal induces reversible DNA kinking. Journal of the American Chemical Society, 136 (50). pp. 17505-17512. ISSN 0002-7863 doi: https://doi.org/10.1021/ja508745x