2022

Khater, M., Watson, K. A. ORCID: https://orcid.org/0000-0002-9987-8539, Boateng, S. Y., Greco, F. and Osborn, H. M. I. ORCID: https://orcid.org/0000-0002-0683-0457 (2022) Halogenated flavonoid derivatives display antiangiogenic activity. Molecules, 27 (15). 4757. ISSN 1420-3049 doi: https://doi.org/10.3390/molecules27154757

Rajasekaran, M. B., Hussain, R., Siligardi, G., Andrews, S. C. ORCID: https://orcid.org/0000-0003-4295-2686 and Watson, K. A. ORCID: https://orcid.org/0000-0002-9987-8539 (2022) Crystal structure and metal binding properties of the periplasmic iron component EfeM from Pseudomonas syringae EfeUOB/M iron-transport system. BioMetals. ISSN 0966-0844 doi: https://doi.org/10.1007/s10534-022-00389-2

2021

Chamata, Y., Jackson, K. G. ORCID: https://orcid.org/0000-0002-0070-3203, Watson, K. A. ORCID: https://orcid.org/0000-0002-9987-8539 and Jauregi, P. (2021) Whey-derived peptides at the heart of the COVID-19 pandemic. International Journal of Molecular Sciences, 22 (21). 11662. ISSN 1422-0067 doi: https://doi.org/10.3390/ijms222111662

Baltulionis, G., Blight, M., Robin, A., Charalampopoulos, D. ORCID: https://orcid.org/0000-0003-1269-8402 and Watson, K. A. ORCID: https://orcid.org/0000-0002-9987-8539 (2021) The role of propeptide-mediated autoinhibition and intermolecular chaperone in the maturation of cognate catalytic domain in leucine aminopeptidase. Journal of Structural Biology, 213 (3). 107741. ISSN 1047-8477 doi: https://doi.org/10.1016/j.jsb.2021.107741

2020

Danson, A. E., McStea, A., Wang, L., Pollitt, A. Y. ORCID: https://orcid.org/0000-0001-8706-5154, Martin-Fernandez, M. L., Moraes, I., Walsh, M. A., MacIntyre, S. and Watson, K. A. ORCID: https://orcid.org/0000-0002-9987-8539 (2020) Super-resolution fluorescence microscopy reveals clustering behaviour of Chlamydia pneumoniae’s major outer membrane protein. Biology, 9 (10). 344. ISSN 2079-7737 doi: https://doi.org/10.3390/biology9100344

Natfji, A. A. ORCID: https://orcid.org/0000-0002-6168-4632, Nikitin, D. O., Semina, I. I., Moustafine, R. I., Khutoryanskiy, V. V. ORCID: https://orcid.org/0000-0002-7221-2630, Lin, H., Stephens, G. J. ORCID: https://orcid.org/0000-0002-8966-4238, Watson, K. A. ORCID: https://orcid.org/0000-0002-9987-8539, Osborn, H. M. I. ORCID: https://orcid.org/0000-0002-0683-0457 and Greco, F. (2020) Conjugation of haloperidol to PEG allows peripheral localisation of haloperidol and eliminates CNS extrapyramidal effects. Journal of Controlled Release, 322. pp. 227-235. ISSN 0168-3659 doi: https://doi.org/10.1016/j.jconrel.2020.02.037

Chamata, Y., Watson, K. A. ORCID: https://orcid.org/0000-0002-9987-8539 and Jauregi, P. (2020) Whey-derived peptides interactions with ACE by molecular docking as a potential predictive tool of natural ACE inhibitors. International Journal of Molecular Sciences, 21 (3). e864. ISSN 1422-0067 doi: https://doi.org/10.3390/ijms21030864

2019

Ravishankar, D., Albadawi, D., Chaggar, V., Patra, P., Williams, H., Salamah, M., Vaiyapuri, R., Dash, P., Patel, K., Watson, K. ORCID: https://orcid.org/0000-0002-9987-8539 and Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517 (2019) Isorhapontigenin, a resveratrol analogue selectively inhibits ADP-stimulated platelet activation. European Journal of Pharmacology, 862. 172627. ISSN 0014-2999 doi: https://doi.org/10.1016/j.ejphar.2019.172627

2018

Salamah, M. F., Ravishankar, D., Kodji, X., Moraes, L. A., Williams, H. F., Vallance, T. M., Albadawi, D. A., Vaiyapuri, R., Watson, K. ORCID: https://orcid.org/0000-0002-9987-8539, Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352, Brain, S. D., Perretti, M. and Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517 (2018) The endogenous antimicrobial cathelicidin LL37 induces platelet activation and augments thrombus formation. Blood Advances, 2 (21). pp. 2973-2985. ISSN 2473-9529 doi: https://doi.org/10.1182/bloodadvances.2018021758

2017

Moir, L., Bochukova, E. G., Dumbell, R., Banks, G., Bains, R. S., Nolan, P. M., Scudamore, C., Simon, M., Watson, K. A. ORCID: https://orcid.org/0000-0002-9987-8539, Keogh, J., Henning, E., Hendricks, A., O'Rahilly, S., Barroso, I., UK10K, C., Sullivan, A. E., Bersten, D. C., Whitelaw, M. L., Kirsch, S., Bentley, E., Farooqi, I. S. and Cox, R. D. (2017) Disruption of the homeodomain transcription factor orthopedia homeobox (Otp) is associated with obesity and anxiety. Molecular Metabolism, 6 (11). pp. 1419-1428. ISSN 2212-8778 doi: https://doi.org/10.1016/j.molmet.2017.08.006

2016

Ravishankar, D., Watson, K. A. ORCID: https://orcid.org/0000-0002-9987-8539, Greco, F. and Osborn, H. M. I. ORCID: https://orcid.org/0000-0002-0683-0457 (2016) Novel synthesised flavone derivatives provide significant insight into the structural features required for enhanced anti-proliferative activity. RSC Advances, 6 (69). pp. 64544-64556. ISSN 2046-2069 doi: https://doi.org/10.1039/C6RA11041J

2015

Wright, B., Watson, K. A. ORCID: https://orcid.org/0000-0002-9987-8539, McGuffin, L. J. ORCID: https://orcid.org/0000-0003-4501-4767, Lovegrove, J. ORCID: https://orcid.org/0000-0001-7633-9455 and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 (2015) GRID and docking analyses reveal a molecular basis for flavonoid inhibition of src-family kinase activity. Journal of Nutritional Biochemistry, 26 (11). pp. 1156-1165. ISSN 0955-2863 doi: https://doi.org/10.1016/j.jnutbio.2015.05.004

Swioklo, S., Watson, K. A. ORCID: https://orcid.org/0000-0002-9987-8539, Williamson, E. M., Farrimond, J. A., Putnam, S. E. and Bicknell, K. A. ORCID: https://orcid.org/0000-0002-5888-1424 (2015) Defining key structural determinants for the pro-osteogenic activity of flavonoids. Journal of Natural Products, 78 (11). pp. 2598-2608. ISSN 1520-6025 doi: https://doi.org/10.1021/acs.jnatprod.5b00075

Ravishankar, D., Watson, K. A. ORCID: https://orcid.org/0000-0002-9987-8539, Boateng, S. Y., Green, R. J., Greco, F. and Osborn, H. M.I. ORCID: https://orcid.org/0000-0002-0683-0457 (2015) Exploring quercetin and luteolin derivatives as antiangiogenic agents. European Journal of Medicinal Chemistry, 97. pp. 259-274. ISSN 0223-5234 doi: https://doi.org/10.1016/j.ejmech.2015.04.056

2014

Osman, A., Symeou, S., Trisse, V., Watson, K. A. ORCID: https://orcid.org/0000-0002-9987-8539, Tzortzis, G. and Charalampopoulos, D. ORCID: https://orcid.org/0000-0003-1269-8402 (2014) Synthesis of prebiotic galactooligosaccharides from lactose using bifidobacterial β-galactosidase (BbgIV) immobilised on DEAE-Cellulose, Q-Sepharose and amino-ethyl agarose. Biochemical Engineering Journal, 82. pp. 188-199. ISSN 1369-703X doi: https://doi.org/10.1016/j.bej.2013.11.020

2013

Antaloae, A. V., Montigny, C., le Maire, M., Watson, K. A. ORCID: https://orcid.org/0000-0002-9987-8539 and Sorensen, T. L.-M. (2013) Optimisation of recombinant production of active human cardiac SERCA2a ATPase. PLoS ONE, 8 (8). e71842. ISSN 1932-6203 doi: https://doi.org/10.1371/journal.pone.0071842

Atanu, F. O., Oviedo-Orta, E. and Watson, K. A. ORCID: https://orcid.org/0000-0002-9987-8539 (2013) A novel transport mechanism for MOMP in Chlamydophila pneumoniae and its putative role in immune-therapy. PLoS ONE, 8 (4). e61139. ISSN 1932-6203 doi: https://doi.org/10.1371/journal.pone.0061139

2011

Sarsam, S. W., Nutt, D. R., Strohfeldt, K. and Watson, K. A. ORCID: https://orcid.org/0000-0002-9987-8539 (2011) Titanocene anticancer complexes and their binding mode of action to human serum albumin: a computational study. Metallomics, 3 (2). pp. 152-161. ISSN 1756-5901 doi: https://doi.org/10.1039/c0mt00041h

2010

Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517, Wagstaff, S. C., Watson, K. A. ORCID: https://orcid.org/0000-0002-9987-8539, Harrison, R. A., Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 and Hutchinson, E. G. (2010) Purification and functional characterisation of rhiminopeptidase A, a novel aminopeptidase from the venom of Bitis gabonica rhinoceros. PLoS Neglected Tropical Diseases, 4 (8). e796. ISSN 1935-2735 doi: https://doi.org/10.1371/journal.pntd.0000796

Rajasekaran, M. B., Mitchell, S. A., Gibson, T. M., Hussain, R., Siligardi, G., Andrews, S. C. ORCID: https://orcid.org/0000-0003-4295-2686 and Watson, K. A. ORCID: https://orcid.org/0000-0002-9987-8539 (2010) Isolation and characterisation of EfeM, a periplasmic component of the putative EfeUOBM iron transporter of Pseudomonas syringae pv. syringae. Biochemical and Biophysical Research Communications, 398 (3). pp. 366-371. ISSN 0006-291X doi: https://doi.org/10.1016/j.bbrc.2010.06.072

Zhou, H. G., Standfuss, J., Watson, K. A. ORCID: https://orcid.org/0000-0002-9987-8539 and Krasel, C. (2010) Structure of full-length arrestin2 in a dimeric crystal form. In: 51st Annual Meeting of the Deutsche-Gesellschaft-fur-Experimentelle-und-Klinische-Pharmakologie-und-Toxikologie, 23-25 Mar 2010, Mainz, Germany.

Rajasekaran, M. B., Nilapwar, S., Andrews, S. C. ORCID: https://orcid.org/0000-0003-4295-2686 and Watson, K. A. ORCID: https://orcid.org/0000-0002-9987-8539 (2010) EfeO-cupredoxins: major new members of the cupredoxin superfamily with roles in bacterial iron transport. BioMetals, 23 (1). pp. 1-17. ISSN 0966-0844 doi: https://doi.org/10.1007/s10534-009-9262-z

2008

Pugazhendhi, D., Watson, K. A. ORCID: https://orcid.org/0000-0002-9987-8539, Mills, S., Botting, N., Pope, G. S. and Darbre, P. D. (2008) Effect of sulphation on the oestrogen agonist activity of the phytoestrogens genistein and daidzein in MCF-7 human breast cancer cells. Journal of Endocrinology, 197 (3). pp. 503-515. ISSN 0022-0795 doi: https://doi.org/10.1677/joe-07-0384

Baba-Dikwa, A., Thompson, D., Spencer, N. J., Andrews, S. C. ORCID: https://orcid.org/0000-0003-4295-2686 and Watson, K. A. ORCID: https://orcid.org/0000-0002-9987-8539 (2008) Overproduction, purification and preliminary X-ray diffraction analysis of YncE, an iron-regulated Sec-dependent periplasmic protein from Escherichia coli. Acta Crystallographica Section F-Structural Biology and Crystallization Communications, 64. pp. 966-969. ISSN 1744-3091 doi: https://doi.org/10.1107/s1744309108029515

Bamford, V. A., Armour, M., Mitchell, S. A., Cartron, M., Andrews, S. C. ORCID: https://orcid.org/0000-0003-4295-2686 and Watson, K. A. ORCID: https://orcid.org/0000-0002-9987-8539 (2008) Preliminary X-ray diffraction analysis of YqjH from Escherichia coli: a putative cytoplasmic ferri-siderophore reductase. Acta Crystallographica Section F-Structural Biology and Crystallization Communications, 64 (9). pp. 792-796. ISSN 1744-3091 doi: https://doi.org/10.1107/S174430910802352X

2007

Lamanna, C., Catalano, A., Carocci, A., Di Mola, A., Franchini, C., Tortorella, V., Vanderheyden, P. M., Sinicropi, M. S., Watson, K. A. ORCID: https://orcid.org/0000-0002-9987-8539 and Sciabola, S. (2007) AT(1) receptor ligands: virtual-screening-based design with TOPP descriptors, synthesis, and biological evaluation of pyrrolidine derivatives. ChemMedChem, 2 (9). pp. 1298-310. ISSN 1860-7179 doi: https://doi.org/10.1002/cmdc.200700082

Cartron, M. L., Mitchell, S., Woodhall, M. R., Andrews, S. C. ORCID: https://orcid.org/0000-0003-4295-2686 and Watson, K. A. ORCID: https://orcid.org/0000-0002-9987-8539 (2007) Preliminary X-ray diffraction analysis of YcdB from Escherichia coli: a novel haem-containing and Tat-secreted periplasmic protein with a potential role in iron transport. Acta Crystallographica Section F-Structural Biology and Crystallization Communications, 63. pp. 37-41. ISSN 1744-3091 doi: https://doi.org/10.1107/s174430910604509x

Armour, M., Cartron, M. L., Mitchell, S. A., Bamford, V. A., Watson, K. A. ORCID: https://orcid.org/0000-0002-9987-8539 and Andrews, S. C. ORCID: https://orcid.org/0000-0003-4295-2686 (2007) YqjH: a novel cytopolasmic siderophore reductase found in eschericia coli. American Journal of Hematology, 82 (6). p. 582. ISSN 0361-8609

2005

Archontis, G., Watson, K. A. ORCID: https://orcid.org/0000-0002-9987-8539, Xie, Q., Andreou, G., Chrysina, E. D., Zographos, S. E., Oikonomakos, N. G. and Karplus, M. (2005) Glycogen phosphorylase inhibitors: a free energy perturbation analysis of glucopyranose spirohydantoin analogues. Proteins, 61 (4). pp. 984-98. ISSN 0887-3585

Watson, K. A. ORCID: https://orcid.org/0000-0002-9987-8539 (2005) How China and Japan are solving the protein puzzle. Global Watch, 44. pp. 4-7.

Watson, K. A. ORCID: https://orcid.org/0000-0002-9987-8539, Chrysina, E. D., Tsitsanou, K. E., Zographos, S. E., Archontis, G., Fleet, G. W. and Oikonomakos, N. G. (2005) Kinetic and crystallographic studies of glucopyranose spirohydantoin and glucopyranosylamine analogs inhibitors of glycogen phosphorylase. Proteins: Structure, Function and Bioinformatics, 61 (4). pp. 966-83. ISSN 0887-3585 doi: https://doi.org/10.1002/prot.20653

2003

Browning, K., Carpenter, E., Watson, K. ORCID: https://orcid.org/0000-0002-9987-8539, Coggins, J., Hawkins, A., Koch, M. and Svergun, D. (2003) Twists and turns: a tale of two shikimate-pathway enzymes. Biochemical Society Transactions, 31 (3). pp. 543-547. ISSN 1470-8752