2019

Fan, L. M., Geng, L., Cahill-Smith, S., Liu, F., Douglas, G., Mckenzie, C.-A., Smith, C., Brooks, G., Channon, K. M. and Li, J.-m. ORCID: https://orcid.org/0000-0002-3294-3818 (2019) Nox2 contributes to age-related oxidative damage to neurons and the cerebral vasculature. The Journal of Clinical Investigation, 129 (8). pp. 3374-3386. ISSN 1558-8238 doi: https://doi.org/10.1172/JCI125173

Giraldo, A., Talavera López, J., Brooks, G. and Fernández-del-Palacio, M. J. (2019) Transthoracic echocardiographic examination in the rabbit model. Journal of Visualized Experiments : JoVE (148). e59457. ISSN 1940-087X doi: https://doi.org/10.3791/59457

2018

Giraldo, A., Talavera López, J., Fernandez-Del-Palacio, M. J., García-Nicolás, O., Seva, J., Brooks, G. and Moraleda, J. M. (2018) Percutaneous contrast echocardiography-guided intramyocardial injection and cell delivery in a large preclinical model. Journal of visualized experiments, 131. e56699. ISSN 1940-087X doi: https://doi.org/10.3791/56699

2017

Fan, L. M., Cahill-Smith, S., Geng, L., Du, J., Brooks, G. and Li, J.-m. ORCID: https://orcid.org/0000-0002-3294-3818 (2017) Aging-associated metabolic disorder induces Nox2 activation and oxidative damage of endothelial function. Free Radical Biology and Medicine, 108. pp. 940-951. ISSN 0891-5849 doi: https://doi.org/10.1016/j.freeradbiomed.2017.05.008

2016

Meijles, D. N., Fan, L. M., Ghazaly, M. M., Howlin, B., Krönke, M., Brooks, G. and Li, J.-m. ORCID: https://orcid.org/0000-0002-3294-3818 (2016) p22phox C242T SNP inhibits inflammatory oxidative damage to endothelial cells and vessels. Circulation, 133 (24). pp. 2391-2403. ISSN 1524-4539 doi: https://doi.org/10.1161/CIRCULATIONAHA.116.021993

2015

Talavera, J., Giraldo, A., Fernández-Del-Palacio, M. J., García-Nicolás, O., Seva, J., Brooks, G. and Moraleda, J. M. (2015) An upgrade on the rabbit model of anthracycline-induced cardiomyopathy: shorter protocol, reduced mortality, and higher incidence of overt dilated cardiomyopathy. BioMed research international, 2015. 465342. ISSN 2314-6133 doi: https://doi.org/10.1155/2015/465342

2014

Dannoura, A., Giraldo, A., Pereira, I., Gibbins, J. ORCID: https://orcid.org/0000-0002-0372-5352, Dash, P., Bicknell, K. ORCID: https://orcid.org/0000-0002-5888-1424 and Brooks, G. (2014) Ibuprofen inhibits migration and proliferation of human coronary artery smooth muscle cells by inducing a differentiated phenotype: role of peroxisome proliferator-activated receptor y. Journal of Pharmacy and Pharmacology, 66 (6). pp. 779-792. ISSN 0022-3573 doi: https://doi.org/10.1111/jphp.12203

2013

Aravindan, L., Bicknell, K.A. ORCID: https://orcid.org/0000-0002-5888-1424, Brooks, G., Khutoryanskiy, V.V. ORCID: https://orcid.org/0000-0002-7221-2630 and Williams, A.C. ORCID: https://orcid.org/0000-0003-3654-7916 (2013) A comparison of thiolated and disulfide‐crosslinked polyethylenimine for nonviral gene delivery. Macromolecular Bioscience, 13 (9). pp. 1163-1173. ISSN 1616-5187 doi: https://doi.org/10.1002/mabi.201300103

2011

Valasek, P., Theis, S., DeLaurier, A., Hinits, Y., Luke, G. N., Otto, A. M., Minchin, J., He, L., Christ, B., Brooks, G., Sang, H., Evans, D. J., Logan, M., Huang, R. and Patel, K. (2011) Cellular and molecular investigations into the development of the pectoral girdle. Developmental Biology, 357 (1). pp. 108-116. ISSN 0012-1606 doi: https://doi.org/10.1016/j.ydbio.2011.06.031

Moseley, F. L., Faircloth, M. E., Lockwood, W., Marber, M. S., Bicknell, K. A. ORCID: https://orcid.org/0000-0002-5888-1424, Valasek, P. and Brooks, G. (2011) Limitations of the MRL mouse as a model for cardiac regeneration. Journal of Pharmacy and Pharmacology, 63 (5). pp. 648-656. ISSN 2042-7148 doi: https://doi.org/10.1111/j.2042-7158.2011.01261.x

2009

Aravindan, L., Bicknell, K. A. ORCID: https://orcid.org/0000-0002-5888-1424, Brooks, G., Khutoryanskiy, V. V. ORCID: https://orcid.org/0000-0002-7221-2630 and Williams, A. C. ORCID: https://orcid.org/0000-0003-3654-7916 (2009) Effect of acyl chain length on transfection efficiency and toxicity of polyethylenimine. International Journal of Pharmaceutics, 378 (1-2). pp. 201-210. ISSN 0378-5173 doi: https://doi.org/10.1016/j.ijpharm.2009.05.052

Coxon, C. H., Bicknell, K. A. ORCID: https://orcid.org/0000-0002-5888-1424, Moseley, F. L. and Brooks, G. (2009) Over expression of Plk1 does not induce cell division in rat cardiac myocytes in vitro. PLoS ONE, 4 (8). e6752. ISSN 1932-6203 doi: https://doi.org/10.1371/journal.pone.0006752

2008

Bicknell, K. A. ORCID: https://orcid.org/0000-0002-5888-1424 and Brooks, G. (2008) Reprogramming the cell cycle machinery to treat cardiovascular disease. Current Opinion in Pharmacology, 8 (2). pp. 193-201. ISSN 1471-4892 doi: https://doi.org/10.1016/j.coph.2007.12.015

Emmott, E., Dove, B. K., Howell, G., Chappell, L. A., Reed, M. L., Boyne, J. R., You, J. H., Brooks, G., Whitehouse, A. and Hiscox, J. A. (2008) Viral nucleolar localisation signals determine dynamic trafficking within the nucleolus. Virology, 380 (2). pp. 191-202. ISSN 1096-0341 doi: https://doi.org/10.1016/j.virol.2008.05.032

2007

Bicknell, K.A. ORCID: https://orcid.org/0000-0002-5888-1424, Coxon, C.N.H. and Brooks, G. (2007) Can the cardiomyocyte cell cycle be reprogrammed? Journal of Molecular and Cellular Cardiology, 42 (4). pp. 706-721. ISSN 0022-2828 doi: https://doi.org/10.1016/j.yjmcc.2007.01.006

Harrison, S.M., Dove, B.K., Rothwell, L., Kaiser, P., Tarpey, I., Brooks, G. and Hiscox, J.A. (2007) Characterisation of cyclin D1 down-regulation in coronavirus infected cells. FEBS Letters, 581 (7). pp. 1275-1286. ISSN 0014-5793 doi: https://doi.org/10.1016/j.febslet.2007.02.039

McKoy, G., Bicknell, K. A. ORCID: https://orcid.org/0000-0002-5888-1424, Patel, K. and Brooks, G. (2007) Developmental expression of myostatin in cardiomyocytes and its effect on foetal and neonatal rat cardiomyocyte proliferation. Cardiovascular Research, 74 (2). pp. 304-312. ISSN 0008-6363 doi: https://doi.org/10.1016/j.cardiores.2007.02.023

Li, J.M., Fan, L.M., George, V.T. and Brooks, G. (2007) Nox2 regulates endothelial cell cycle arrest and apoptosis via p21 (cip1) and p53. Free Radical Biology and Medicine, 43 (6). pp. 976-986. ISSN 0891-5849 doi: https://doi.org/10.1016/j.freeradbiomed.2007.06.001

George, V.T., Brooks, G. and Humphrey, T.C. (2007) Regulation of cell cycle and stress responses to hydrostatic pressure in fission yeast. Molecular Biology of the Cel, 18 (10). pp. 4168-4179. ISSN 1059-1524 doi: https://doi.org/10.1091/mbc.E06-12-1141

Moseley, F.L., Bicknell, K.A. ORCID: https://orcid.org/0000-0002-5888-1424, Marber, M.S. and Brooks, G. (2007) The use of proteomics to identify novel therapeutic targets for the treatment of disease. Journal of Pharmacy and Pharmacology, 59 (5). pp. 609-628. ISSN 0022-3573 doi: https://doi.org/10.1211/jpp.59.5.0001

2006

Dove, B., Brooks, G., Bicknell, K. A. ORCID: https://orcid.org/0000-0002-5888-1424, Wurm, T. and Hiscox, J. A. (2006) Cell cycle perturbations induced by infection with the coronavirus infectious bronchitis virus and their effect on virus replication. Journal of Virology, 80 (8). pp. 4147-4156. ISSN 0022-538X doi: https://doi.org/10.1128/jvi.80.8.4147-4156.2006

Dove, B.K., You, J.H., Reed, M.L., Emmett, S.R., Brooks, G. and Hiscox, J.A. (2006) Changes in nucleolar morphology and proteins during infection with the coronavirus infectious bronchitis virus. Cellular Microbiology, 8 (7). pp. 1147-1157. ISSN 1462-5814 doi: https://doi.org/10.1111/j.1462-5822.2006.00698.x

Movassagh, M., Bicknell, K. A. ORCID: https://orcid.org/0000-0002-5888-1424 and Brooks, G. (2006) Characterisation and regulation of E2F-6 and E2F-6b in the rat heart: a potential target for myocardial regeneration? Journal of Pharmacy and Pharmacology, 58 (1). pp. 73-82. ISSN 0022-3573 doi: https://doi.org/10.1211/jpp.58.1.0009

Reed, M.L., Dove, B.K., Jackson, R.M., Collins, R., Brooks, G. and Hiscox, J.A. (2006) Delineation and modelling of a nucleolar retention signal in the coronavirus nucleocapsid protein. Traffic, 7 (7). pp. 833-848. ISSN 1398-9219 doi: https://doi.org/10.1111/j.1600-0854.2006.00424.x

Dove, B.K., Bicknell, K. ORCID: https://orcid.org/0000-0002-5888-1424, Brooks, G., Harrison, S. and Hiscox, J.A. (2006) Infectious bronchitis coronavirus induces cell-cycle perturbations. In: Perlman, S. and Holmes, K.V. (eds.) Nidoviruses: toward control of SARS and other nidovirus diseases. Advances in Experimental Medicine and Biology, 581. Springer-Verlag, Berlin, pp. 357-362. ISBN 9780387262024

Morissette, M.R., Cook, S.A., Foo, S., McKoy, G., Ashida, N., Novikov, M., Scherrer-Crosbie, M., Li, L., Matsui, T., Brooks, G. and Rosenzweig, A. (2006) Myostatin regulates cardiomyocyte growth through modulation of Akt signaling. Circulation Research, 99 (1). pp. 15-24. ISSN 0009-7330 doi: https://doi.org/10.1161/01.RES.0000231290.45676.d4

2005

Brooks, G. (2005) Cyclins, cyclin-dependent kinases, and cyclin-dependent kinase inhibitors: detection methods and activity measurements. In: Humphrey, T. and Brooks, G. (eds.) Cell cycle control: mechanisms and protocols. Methods in molecular biology, 296. Humana Press, New Jersey, pp. 291-298. ISBN 9781588291448 doi: https://doi.org/10.1385/1-59259-857-9:291

Bicknell, K. ORCID: https://orcid.org/0000-0002-5888-1424, Brooks, G., Kaiser, P., Chen, H. Y., Dove, B. K. and Hiscox, J. A. (2005) Nucleolin is regulated both at the level of transcription and translation. Biochemical and Biophysical Research Communications, 332 (3). pp. 817-822. ISSN 0006-291X doi: https://doi.org/10.1016/j.bbrc.2005.05.022

Harper, J.V. and Brooks, G. (2005) The mammalian cell cycle: an overview. In: Humphrey, T. and Brooks, G. (eds.) Cell cycle control: mechanisms and protocols. Methods in molecular biology, 296. Humana Press, New Jersey, pp. 113-153. ISBN 9781588291448 doi: https://doi.org/10.1385/1-59259-857-9:113

2004

Brooks, G. (2004) Cyclins, cyclin-dependent kinases, and cyclin-dependent kinase inhibitors: detection methods and activity measurements. Methods in Molecular Biology, 296. pp. 291-8. ISSN 1064-3745 doi: https://doi.org/10.1385/1592598579

Bicknell, K. A. ORCID: https://orcid.org/0000-0002-5888-1424, Coxon, C. H. and Brooks, G. (2004) Forced expression of the cyclin B1-CDC2 complex induces proliferation in adult rat cardiomyocytes. The Biochemical Journal, 382 (2). pp. 411-6. ISSN 1470-8728

Harper, J. V. and Brooks, G. (2004) The Mammalian cell cycle: an overview. Methods in Molecular Biology, 296. pp. 113-54. ISSN 1064-3745

Gray, L. S., Perez-Reyes, E., Gamorra, J. C., Haverstick, D. M., Shattock, M., McLatchie, L., Harper, J., Brooks, G., Heady, T. and Macdonald, T. L. (2004) The role of voltage gated T-type Ca2+ channel isoforms in mediating "capacitative" Ca2+ entry in cancer cells. Cell Calcium, 36 (6). pp. 489-97. ISSN 0143-4160 doi: https://doi.org/10.1016/j.ceca.2004.05.001

2003

Li, J. M., Fan, L. M., Shah, A. and Brooks, G. (2003) Targeting αvβ3 and α5β1 for gene delivery to proliferating VSMCs: synergistic effect of TGF-β1. American Journal of Physiology-Heart and Circulatory Physiology, 285 (3). H1123-H1131. ISSN 0363-6135

Vara, D., Bicknell, K. A., Coxon, C. H. and Brooks, G. (2003) Inhibition of E2F abrogates the development of cardiac myocyte hypertrophy. The Journal of Biological Chemistry, 278 (24). pp. 21388-21394. ISSN 1083-351X doi: https://doi.org/10.1074/jbc.M212612200

Wang, Y. Q., Brooks, G., Harper, J., Li, Y. Q., Zhu, C. B., Yuan, W. Z. and Wu, X. S. (2003) Inhibition of vascular smooth muscle cell proliferation by non-steroidal anti-inflammatory drugs. Shi Yan Sheng Wu Xue Bao, 36 (2). pp. 85-90. ISSN 0001-5334

Brooks, G., Yu, X. M., Wang, Y. Q., Crabbe, M. J. C., Shattock, M. J. and Harper, J. V. (2003) Non-steroidal anti-inflammatory drugs (NSAIDs) inhibit vascular smooth muscle cell proliferation via differential effects on the cell cycle. Journal of Pharmacy and Pharmacology, 55 (4). pp. 519-526. ISSN 0022-3573 doi: https://doi.org/10.1211/002235702775

Mulgrew, C. J., Shattock, M. J., Brooks, G. and Hendry, B. M. (2003) Targeting T-type calcium channels in human mesangial cell proliferation. Journal of the American Society of Nephrology, 14. 342A-342A. ISSN 1046-6673

Bicknell, K. A. ORCID: https://orcid.org/0000-0002-5888-1424, Surry, E. L. and Brooks, G. (2003) Targeting the cell cycle machinery for the treatment of cardiovascular disease. Journal of Pharmacy and Pharmacology, 55 (5). pp. 571-591. ISSN 2042-7158 doi: https://doi.org/10.1211/002235703765344487

2002

Chen, H., Wurm, T., Britton, P., Brooks, G. and Hiscox, J.A. (2002) Interaction of the coronavirus nucleoprotein with nucleolar antigens and the host cell. Journal of Virology, 76 (10). pp. 5233-5250. ISSN 0022-538X doi: https://doi.org/10.1128/JVI.76.10.5233-5250.2002

Bicknell, K. A. ORCID: https://orcid.org/0000-0002-5888-1424 and Brooks, G. (2002) Methods for delivering DNA to target tissues and cells. In: Brooks, G. (ed.) Gene Therapy: Use of DNA as a Drug. The Pharmaceutical Press, UK, pp. 23-49. ISBN 9780853694557

Mahadeva, H., Brooks, G., Chong, N.W., Lodwick, D. and Samani, N.J. (2002) ms1, a novel stress-responsive, muscle-specific gene that is up-regulated in the early stages of pressure overload-induced left ventricular hypertrophy. FEBS Letters, 521 (1-3). pp. 100-104. ISSN 0014-5793

2001

Wurm, T., Chen, H., Hodgson, T., Britton, P., Brooks, G. and Hiscox, J.A. (2001) Localization to the nucleolus is a common feature of coronavirus nucleoproteins and the protein may disrupt host cell division. Journal of Virology, 75 (19). pp. 9345-9356. ISSN 0022-538X doi: https://doi.org/10.1128/JVI.75.19.9345-9356.2001

Hiscox, J.A., Wurm, T., Wilson, L., Britton, P., Cavanagh, D. and Brooks, G. (2001) The coronavirus infectious bronchitis virus nucleoprotein localizes to the nucleolus. Journal of Virology, 75 (1). pp. 506-512. ISSN 0022-538X doi: https://doi.org/10.1128/JVI.75.1.506-512.2001

1999

Poolman, R.A., Li, J.-M., Durand, B. and Brooks, G. (1999) Altered expression of cell cycle proteins and prolonged duration of cardiac myocyte hyperplasia in p27KIP1 knockout mice. Circulation Research, 85 (2). pp. 117-127. ISSN 0009-7330

Li, J.-M. and Brooks, G. (1999) Cell regulatory molecules and the cardiovascular system: Potential targets for therapy. European Heart Journal, 20 (6). pp. 406-420. ISSN 0195-668X doi: https://doi.org/10.1053/euhj.1998.1308

Brooks, G. and La Thangue, N.B. (1999) The cell cycle and drug discovery: The promise and the hope. Drug Discovery Today, 4 (10). pp. 455-463. ISSN 1359-6446 doi: https://doi.org/10.1016/S1359-6446(99)01400-2

1998

Poolman, R.A., Gilchrist, R. and Brooks, G. (1998) Cell cycle profiles and expression of p21CIP1 and P27KIP1 during myocyte development. International Journal of Cardiology, 67 (1). pp. 133-142. ISSN 0167-5273 doi: https://doi.org/10.1016/S0167-5273(98)00320-9

Atsumi, T., Khamashta, M.A., Haworth, R.S., Brooks, G., Amengual, O., Ichiawa, K., Koike, T. and Hughes, G.R.V. (1998) Arterial disease and thrombosis in the antiphospholipid syndrome (APS): A pathogenic role for endothelin-1 (ET-1). Arthritis and Rheumatism, 41 (5). pp. 800-807. ISSN 0004-3591 doi: https://doi.org/10.1002/1529-0131(199805)41:5<800::AID-ART5>3.0.CO;2-J

Brooks, G., Poolman, R.A. and Li, J.-M. (1998) Arresting developments in the cardiac myocyte cell cycle: Role of cyclin-dependent kinase inhibitors. Cardiovascular Research, 39 (2). pp. 301-311. ISSN 0008-6363 doi: https://doi.org/10.1016/S0008-6363(98)00125-4

Galinanes, M., Goss, M.W., McGill, C.J., Hearse, D.J. and Brooks, G. (1998) Diacylglycerol-induced protection against injury during ischemia and reperfusion can be achieved without activation of protein kinase C in the rat heart: Comparative studies with ischemic preconditioning. International Journal of Cardiology, 65 (2). pp. 129-138. ISSN 0167-5273 doi: https://doi.org/10.1016/S0167-5273(98)00108-9

Haworth, R.S., Brooks, G., Cummins, P., Dobie, K., Chilton, D.C. and Avkiran, M. (1998) Differential changes in transforming growth factor β isoform expression during postnatal cardiac growth. Biochemical and biophysical research communications, 245 (3). pp. 923-927. ISSN 0006-291X doi: https://doi.org/10.1006/bbrc.1998.8528

Poolman, R.A. and Brooks, G. (1998) Expressions and activities of cell cycle regulatory molecules during the transition from myocyte hyperplasia to hypertrophy. Journal of Molecular and Cellular Cardiology, 30 (10). pp. 2121-2135. ISSN 0022-2828 doi: https://doi.org/10.1006/jmcc.1998.0808

Li, J.-M., Poolman, R.A. and Brooks, G. (1998) Role of G1 phase cyclins and cyclin dependent kinases during hypertrophic growth of adult rat cardiomyocytes. American Journal of Physiology-Heart and Circulatory Physiology, 275 (3 Part 2). H814-H822. ISSN 0363-6135

1997

Li, J.-M. and Brooks, G. (1997) Differential protein expression and subcellular distribution of TGFβ1, β2 and β3 in cardiomyocytes during pressure overload-induced hypertrophy. Journal of Molecular and Cellular Cardiology, 29 (8). pp. 2213-2224. ISSN 0022-2828 doi: https://doi.org/10.1006/jmcc.1997.0457

Brooks, G., Poolman, R.A., McGill, C.J. and Li, J.-M. (1997) Expression and activities of cyclins and cyclin-dependent kinases in developing rat ventricular myocytes. Journal of Molecular and Cellular Cardiology, 29 (8). pp. 2261-2271. ISSN 0022-2828 doi: https://doi.org/10.1006/jmcc.1997.0471

Brooks, G., Goss, M.W., Rozengurt, E. and Galinanes, M. (1997) Phorbol ester, but not ischemic preconditioning, activates protein kinase D in the rat heart. Journal of Molecular and Cellular Cardiology, 29 (8). pp. 2273-2284. ISSN 0022-2828 doi: https://doi.org/10.1006/jmcc.1997.0466

Haworth, R.S., Yasutake, M., Brooks, G. and Avkiran, M. (1997) Cardiac Na+/H+ exchanger during post-natal development in the rat: Changes in mRNA expression and sarcolemmal activity. Journal of Molecular and Cellular Cardiology, 29 (1). pp. 321-332. ISSN 0022-2828 doi: https://doi.org/10.1006/jmcc.1996.0277

Li, J.-M. and Brooks, G. (1997) Downregulation of cyclin-dependent kinase inhibitors p21 and p27 in pressure-overload hypertrophy. American Journal of Physiology-Heart and Circulatory Physiology, 273 (2). H1358-H1367. ISSN 0363-6135

McGill, C.J. and Brooks, G. (1997) Expression and regulation of 80K/MARCKS, a major substrate of protein kinase C, in the developing rat heart. Cardiovascular Research, 34. pp. 368-376. ISSN 0008-6363 doi: https://doi.org/10.1016/S0008-6363(97)00041-2

1996

Brooks, G., Brooks, S.F. and Goss, M.W. (1996) MARCKS functions as a novel growth/tumour suppressor in cells of melanocyte origin. Carcinogenesis, 17 (4). pp. 683-689. ISSN 0143-3334 doi: https://doi.org/10.1093/carcin/17.4.683

Brooks, G. and Hearse, D.J. (1996) Role of protein kinase C in ischemic preconditioning: Player or spectator? Circulation Research, 79 (3). pp. 628-631. ISSN 0009-7330

1995

McGill, C.J. and Brooks, G. (1995) Cell cycle control mechanisms and their role in cardiac growth. Cardiovascular Research, 30 (4). pp. 557-569. ISSN 0008-6363

1994

Brooks, G. (1994) Gene therapy. Pharmaceutical Journal, 252. pp. 256-260. ISSN 0031-6873

Brooks, G. (1994) Transgenic animals. Pharmaceutical Journal, 253 (6802). pp. 227-231. ISSN 0031-6873

Goss, M.W. and Brooks, G. (1994) The polymerase chain reaction. Pharmaceutical Journal, 253. pp. 884-889. ISSN 0031-6873

Brooks, G. (1994) The role of 80K/MARCKS, a specific substrate of protein kinase C, in cell growth and tumour progression. Pigment Cell Research, 7 (6). pp. 451-457. ISSN 0893-5785 doi: https://doi.org/10.1111/j.1600-0749.1994.tb00074.x

1993

Brooks, G., Goss, M.W., East, J.A. and Hart, I.R. (1993) Growth of melanocytic cells is associated with down-regulation of protein kinase C α,δ and ε isoforms: Possible role of diacylglycerol. The Journal of Biological Chemistry, 268. pp. 23868-23875. ISSN 1083-351X

1992

Brooks, G., Goss, M.W. and Hart, I.R. (1992) Differential induction of 12-O-tetradecanoylphorbol 13-acetate sequence gene expression in murine melanocytes and melanoma cells. Molecular Carcinogenesis, 5 (4). pp. 328-333. ISSN 0899-1987 doi: https://doi.org/10.1002/mc.2940050414

1991

Brooks, G., Wilson, R.E., Dooley, T.P., Goss, M.W. and Hart, I.R. (1991) Protein kinase C down-regulation, and not transient activation, correlates with melanocyte growth. Cancer Research, 51. pp. 3281-3288. ISSN 0008-5472

1990

Evans, A.T., Brooks, G. and Evans, F.J. (1990) Non-promoting diterpene esters can induce Epstein-Barr Virus early antigen expression in the Raji cell line. Cancer Letters, 49 (1). pp. 25-29. ISSN 0304-3835 doi: https://doi.org/10.1016/0304-3835(90)90135-K

Brooks, G. and Brooks, S.F. (1990) Both tumour-promoting and non-promoting phorbol esters inhibit 125I-EGF binding and stimulate the phosphorylation of a 80kd protein kinase C substrate protein in intact Swiss 3T3 cells. Carcinogenesis, 11 (4). pp. 667-672. ISSN 0143-3334 doi: https://doi.org/10.1093/carcin/11.4.667

Brooks, G., Evans, A.T., Aitken, A., Evans, F.J., Rizk, A.-F., Hammouda, F.M., El-Missery, M.M. and Ismail, S.E. (1990) Daphnane diterpenes of Thymelaea hirsuta. Phytochemistry, 29 (7). pp. 2235-2237. ISSN 0031-9422 doi: https://doi.org/10.1016/0031-9422(90)83044-2

Brooks, G. (1990) Drug-induced photosensitivity. Pharmaceutical Journal, 245. pp. 19-21. ISSN 0031-6873

Brooks, G., Birch, M. and Hart, I.R. (1990) Effects of biologically active tumour-promoting and non-promoting phorbol esters on in vivo growth of melanocytic cells. Pigment Cell Research, 3 (2). pp. 98-100. ISSN 0893-5785 doi: https://doi.org/10.1111/j.1600-0749.1990.tb00328.x

Brooks, G., Goss, M.W. and Hart, I.R. (1990) Inhibition of 125I-epidermal growth factor binding to murine fibroblasts and keratinocytes by irradiation with ultraviolet-B light. Carcinogenesis, 11 (7). pp. 1223-1227. ISSN 0143-3334 doi: https://doi.org/10.1093/carcin/11.7.1223

Brooks, G., Evans, A.T., Markby, D.P., Harrison, M.E., Baldwin, M.A. and Evans, F.J. (1990) An ingenane diterpene from Belizian Mabea excelsa. Phytochemistry, 29 (5). pp. 1615-1617. ISSN 0031-9422 doi: https://doi.org/10.1016/0031-9422(90)80132-Z

1989

Brooks, G., Evans, A.T., Aitken, A. and Evans, F.J. (1989) Tumour-promoting and hyperplastic effects of phorbol and daphnane esters in CD-1 mouse skin and a synergistic effect of calcium ionophore with a non-promoting activator of protein kinase C. Carcinogenesis, 10 (2). pp. 283-288. ISSN 0143-3334

Markby, D.P., Brooks, G., Evans, A.T. and Evans, F.J. (1989) The poison sap tree and its pro-inflammatory constituent: a potent activator of protein kinase C. Lancet, 8560. p. 1320. ISSN 0140-6736

1988

Brooks, G., Morrice, N., Aitken, A. and Evans, F.J. (1988) Partial synthesis of the phorbol ester probe, Sapintoxin D. Phytochemistry, 27 (5). pp. 1523-1524. ISSN 0031-9422

1987

Brooks, G., Evans, A.T., Aitken, A. and Evans, F.J. (1987) Sapintoxin A, a fluorescent phorbol ester that is a potent activator of protein kinase C but is not a tumour promoter. Cancer Letters, 38. pp. 165-170. ISSN 0304-3835

Edwards, M.C., Williamson, E.M., Foumokong, E., Brooks, G. and Evans, F.J. (1987) Secretion and properties of a polypeptide factor generated by phorbol ester stimulation of human blood platelets. Biochemical Pharmacology, 36 (14). pp. 2418-2420. ISSN 0006-2952 doi: https://doi.org/10.1016/0006-2952(87)90613-7

Brooks, G., Evans, A.T., Morrice, N., Ellis, C., Aitken, A. and Evans, F.J. (1987) Toxic phorbol esters from Chinese Tallow (Sapium sebiferum L.Roxb.). Toxicon, 25 (11). pp. 1229-1233. ISSN 0041-0101 doi: https://doi.org/10.1016/0041-0101(87)90141-3

Ellis, C.A., Brooks, S.F., Brooks, G., Evans, A.T., Morrice, N., Evans, F.J. and Aitken, A. (1987) The effects of phorbol esters with different activities on protein kinase C. Phytotherapy Research, 1 (4). 187 -192. ISSN 0951-418X doi: https://doi.org/10.1002/ptr.2650010412