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Items where Division is "Institute for Cardiovascular and Metabolic Research (ICMR)" and Year is 2018

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Number of items: 42.

A

Ahmad, F. and Leake, D. (2018) Antioxidants inhibit low density lipoprotein oxidation less at lysosomal pH: a possible explanation as to why the clinical trials of antioxidants might have failed. Chemistry and Physics of Lipids, 213. pp. 13-24. ISSN 0009-3084 doi: https://doi.org/10.1016/j.chemphyslip.2018.03.001

B

Barrese, V., Stott, J. B., Figueiredo, H. B., Aubdool, A. A., Hobbs, A. J., Jepps, T. A., McNeish, A. and Greenwood, I. A. (2018) Angiotensin II promotes KV7.4 channels degradation through reduced interaction with HSP90 (heat shock protein 90). Hypertension, 71 (6). pp. 1091-1100. ISSN 1524-4563 doi: https://doi.org/10.1161/HYPERTENSIONAHA.118.11116

Bye, A. P. and Gibbins, J. M. (2018) Move along, nothing to see here: Btk inhibitors stop platelets sticking to plaques. Journal of Thrombosis and Haemostasis, 16 (8). pp. 1461-1463. ISSN 1538-7933 doi: https://doi.org/10.1111/jth.14201

Bye, A. P., Unsworth, A. J. and Gibbins, J. M. (2018) Screening and high-throughput platelet assays. In: Gibbins, J. M. and Mahaut-Smith, M. (eds.) Platelets and Megakaryocytes: Volume 4, Advanced Protocols and Perspectives. Humana Press, New York, pp. 81-94. ISBN 9781493985845 doi: https://doi.org/10.1007/978-1-4939-8585-2_5

D

Dede, E., Tindall, M. J., Cherrie, J. W., Hankin, S. and Collins, C. (2018) Physiologically-based pharmacokinetic and toxicokinetic models for estimating human exposure to five toxic elements through oral ingestion. Environmental toxicology and pharmacology, 57. pp. 104-114. ISSN 1872-7077 doi: https://doi.org/10.1016/j.etap.2017.12.003

Dunster, J. L., Panteleev, M. A., Gibbins, J. M. and Sveshnikova, A. N. (2018) Mathematical techniques for understanding platelet regulation and the development of new pharmacological approaches. In: Gibbins, J. M. and Mahaut-Smith, M. (eds.) Platelets and Megakaryocytes: Volume 4, Advanced Protocols and Perspectives. Methods in Molecular Biology, 1812. Humana Press, New York, pp. 255-279. ISBN 9781493985845 doi: https://doi.org/10.1007/978-1-4939-8585-2_15

Dustin, M. L. and Pollitt, A. Y. (2018) The study of platelet receptors using artificial lipid bilayers. In: Gibbins, J. M. and Mahaut-Smith, M. (eds.) Platelets and Megakaryocytes: Volume 4, Advanced Protocols and Perspectives. Methods in Molecular Biology, 1812. Humana Press, New York, pp. 127-137. ISBN 9781493985845 doi: https://doi.org/10.1007/978-1-4939-8585-2_8

E

Edgington, M. P. and Tindall, M. J. (2018) Mathematical analysis of the Escherichia coli chemotaxis signalling pathway. Bulletin of Mathematical Biology, 80 (4). pp. 758-787. ISSN 1522-9602 doi: https://doi.org/10.1007/s11538-018-0400-z

Elofsson, A., Joo, K., Keasar, C., Lee, J., Maghrabi, A. H. A., Manavalan, B., McGuffin, L. J., Ménendez Hurtado, D., Mirabello, C., Pilstål, R., Sidi, T., Uziela, K. and Wallner, B. (2018) Methods for estimation of model accuracy in CASP12. Proteins: Structure, Function, and Bioinformatics, 86. pp. 361-373. ISSN 1097-0134 doi: https://doi.org/10.1002/prot.25395

F

Fallaize, R. and Lovegrove, J. (2018) Nutrition in marginalised groups. In: Bonner, A. (ed.) Social Determinants of Health: An Interdisciplinary Approach to Social Inequality and Well-Being. Policy Press, Bristol, pp. 41-53. ISBN 9781447336860

Fallaize, R., Livingstone, K. M., Celis-Morales, C., Macready, A. L., San-Cristobal, R., Navas-Carretero, S., Marsaux, C. F. M., O’Donovan, C. B., Kolossa, S., Moschonis, G., Walsh, M. C., Gibney, E. R., Brennan, L., Bouwman, J., Manios, Y., Jarosz, M., Martinez, J. A., Daniel, H., Saris, W. H. M., Gundersen, T. E., Drevon, C. A., Gibney, M. J., Mathers, J. C. and Lovegrove, J. A. (2018) Association between diet-quality scores, adiposity, total cholesterol and markers of nutritional status in European adults: findings from the Food4Me study. Nutrients, 10 (1). pp. 49-64. ISSN 2072-6643 doi: https://doi.org/10.3390/nu10010049

Fekete, A. A., Giromini, C., Chatzidiakou, Y., Givens, D. I. and Lovegrove, J. A. (2018) Whey protein lowers systolic blood pressure and Ca-caseinate reduces serum TAG after a high-fat meal in mildly hypertensive adults. Scientific Reports, 8. 5026. ISSN 2045-2322 doi: https://doi.org/10.1038/s41598-018-23333-2

Flora, G. D. (2018) Non-genomic effects of the Pregnane X Receptor (PXR) and Retinoid X Receptor (RXR) in platelets. PhD thesis, University of Reading. doi: https://doi.org/10.17864/1926.80709

Fuentos, E., Gibbins, J. M., Holbrook, L. M. and Palomo, I. (2018) NADPH oxidase 2 (NOX2): a key target of oxidative stress-mediated platelet activation and thrombosis. Trends in Cardiovascular Medicine, 28 (7). pp. 429-434. ISSN 1050-1738 doi: https://doi.org/10.1016/j.tcm.2018.03.001

G

Gibbins, J. M. and Mahaut-Smith, M., eds. (2018) Platelets and Megakaryocytes. Volume 4, Advanced Protocols and Perspectives. Methods in Molecular Biology, 1812. Humana Press, pp304. ISBN 9781493985845 doi: https://doi.org/10.1007/978-1-4939-8585-2

Griffin, B. A. and Lovegrove, J. A. (2018) Butter increases high-density lipoprotein functional capacity: is this compensation for its adverse effect on serum low-density lipoprotein cholesterol? Journal of Nutrition, 148 (7). pp. 1069-1070. ISSN 1541-6100 doi: https://doi.org/10.1093/jn/nxy086

Griffin, B. A., Walker, C. G., Jebb, S. A., Moore, C., Frost, G. S., Goff, L., Sanders, T. A. B., Lewis, F., Griffin, M., Gitau, R. and Lovegrove, J. A. (2018) APOE4 genotype exerts greater benefit in lowering plasma cholesterol and apolipoprotein B than wild type (E3/E3), after replacement of dietary saturated fats with low glycaemic index carbohydrates. Nutrients, 10 (10). 1524. ISSN 2072-6643 doi: https://doi.org/10.3390/nu10101524

Guo, J., Jackson, K. G., Givens, D. I. and Lovegrove, J. A. (2018) Reply to TR Hill and I Kyriazakis. Journal of Nutrition, 148 (4). p. 665. ISSN 1541-6100 doi: https://doi.org/10.1093/jn/nxy010

K

Keasar, C., McGuffin, L. J., Wallner, B., Chopra, G., Adhikari, B., Bhattacharya, D., Blake, L., Bortot, L. O., Cao, R., Dhanasekaran, B. K., Dimas, I., Faccioli, R. A., Faraggi, E., Ganzynkowicz, R., Ghosh, S., Ghosh, S., Giełdoń, A., Golon, L., He, Y., Heo, L., Hou, J., Khan, M., Khatib, F., Khoury, G. A., Kieslich, C., Kim, D. E., Krupa, P., Lee, G. R., Li, H., Li, J., Lipska, A., Liwo, A., Maghrabi, A. H. A., Mirdita, M., Mirzaei, S., Mozolewska, M. A., Onel, M., Ovchinnikov, S., Shah, A., Shah, U., Sidi, T., Sieradzan, A. K., Ślusarz, M., Ślusarz, R., Smadbeck, J., Tamamis, P., Trieber, N., Wirecki, T., Yin, Y., Zhang, Y., Bacardit, J., Baranowski, M., Chapman, N., Cooper, S., Defelicibus, A., Flatten, J., Koepnick, B., Popović, Z., Zaborowski, B., Baker, D., Cheng, J., Czaplewski, C., Delbem, A. C. B., Floudas, C., Kloczkowski, A., Ołdziej, S., Levitt, M., Scheraga, H., Seok, C., Söding, J., Vishveshwara, S., Xu, D. and Crivelli, S. N. (2018) An analysis and evaluation of the WeFold collaborative for protein structure prediction and its pipelines in CASP11 and CASP12. Scientific Reports, 8 (1). 9939. ISSN 2045-2322 doi: https://doi.org/10.1038/s41598-018-26812-8

L

Limbu, R., Cottrell, G. S. and McNeish, A. J. (2018) Characterisation of the vasodilation effects of DHA and EPA, n-3 PUFAs (fish oils), in rat aorta and mesenteric resistance arteries. PLoS ONE, 13 (2). e0192484. ISSN 1932-6203 doi: https://doi.org/10.1371/journal.pone.0192484

Lovegrove, J. (2018) 30-Second Nutrition. 30 Second. Ivy Press, London, pp160. ISBN 9781782405535

Lovegrove, J. (2018) Hugh Macdonald Sinclair. In: 30-second Nutrition. 30 Second. Ivy Press, London, United Kingdom, pp. 130-131. ISBN 9781782405535

Lovegrove, J. (2018) Milk and dairy. In: 30-Second Nutrition. 30 Second. Ivy Press, London, United Kingdom, pp. 60-61. ISBN 9781782405535

Lovegrove, J. and Griffin, B. (2018) Dietary fats and heart disease. In: 30-Second Nutrition. 30 Second. Ivy Press, London, United Kingdom, pp. 100-101. ISBN 9781782405535

M

Macready, A., Fallaize, R., Butler, L. T., Ellis, J. A., Kuznesof, S., Frewer, L. J., Celis-Morales, C., Livingstone, K. M., Araújo-Soares, V., Fischer, A. R. H., Stewart-Knox, B. J., Mathers, J. C. and Lovegrove, J. A. (2018) Application of behavior change techniques in a personalized nutrition Electronic Health intervention study: protocol for the web-based Food4Me randomized controlled trial. JMIR Research Protocols, 7 (4). e87. ISSN 1929-0748 doi: https://doi.org/10.2196/resprot.8703

Maldonado, E. M., Fisher, C. P., Mazzatti, D. J., Barber, A. L., Tindall, M. J., Plant, N. J., Kierzek, A. M. and Moore, J. B. (2018) Multi-scale, whole-system models of liver metabolic adaptation to fat and sugar in non-alcoholic fatty liver disease. NPJ Systems Biology and Applications, 4. 33. ISSN 2056-7189 doi: https://doi.org/10.1038/s41540-018-0070-3

Mazet, F. and Fry, M. J. (2018) Precise quantification of platelet proteins and their phosphorylation states. In: Gibbins, J. M. and Mahaut-Smith, M. (eds.) Platelets and Megakaryocytes: Volume 4, Advanced Protocols and Perspectives. Humana Press, New York, pp. 113-125. ISBN 9781493985845 doi: https://doi.org/10.1007/978-1-4939-8585-2_7

McGuffin, L., Shuid, A. N., Kempster, R., Maghrabi, A. H.A., Nealon, J. O., Salehe, B. R., Atkins, J. D. and Roche, D. B. (2018) Accurate template-based modeling in CASP12 using the IntFOLD4-TS, ModFOLD6, and ReFOLD methods. Proteins: Structure, Function, and Bioinformatics, 86. pp. 335-344. ISSN 0887-3585 doi: https://doi.org/10.1002/prot.25360

Molica, F., Figueroa, X. F., Kwak, B. R., Isakson, B. E. and Gibbins, J. M. (2018) Connexins and pannexins in vascular function and disease. International Journal of Molecular Sciences, 19 (6). 1663. ISSN 1422-0067 doi: https://doi.org/10.3390/ijms19061663

O

Ojo, O. O. and Leake, D. S. (2018) Low density lipoprotein oxidation by ferritin at lysosomal pH. Chemistry and Physics of Lipids, 217. pp. 51-57. ISSN 0009-3084 doi: https://doi.org/10.1016/j.chemphyslip.2018.09.016

P

Palmer, C., Peri, F., Neumann, F., Ahmad, F., Leake, D. S. and Pirianov, G. (2018) The synthetic glycolipid-based TLR4 antagonist FP7 negatively regulates in vitro and in vivo haematopoietic and non-haematopoietic vascular TLR4 signalling. Innate Immunity, 24 (7). pp. 411-421. ISSN 1753-4267 doi: https://doi.org/10.1177/1753425918798904

Pool, F., Currie, R., Sweby, P. K., Salazar, J. D. and Tindall, M. J. (2018) A mathematical model of the mevalonate cholesterol biosynthesis pathway. Journal of Theoretical Biology, 443. pp. 157-176. ISSN 0022-5193 doi: https://doi.org/10.1016/j.jtbi.2017.12.023

Pool, F., Sweby, P. K. and Tindall, M. J. (2018) An integrated mathematical model of cellular cholesterol biosynthesis and lipoprotein metabolism. Processes, 6 (8). 134. ISSN 2227-9717 doi: https://doi.org/10.3390/pr6080134

R

Rathnayake, K. M., Weech, M., Jackson, K. G. and Lovegrove, J. A. (2018) Meal fatty acids have differential effects on postprandial blood pressure and biomarkers of endothelial function but not vascular reactivity in postmenopausal women in the Randomized Controlled Dietary Intervention and VAScular function (DIVAS)-2 Study. Journal of Nutrition, 148 (3). pp. 348-357. ISSN 1541-6100 doi: https://doi.org/10.1093/jn/nxx042

Rathnayake, K., Weech, M., Jackson, K. and Lovegrove, J. (2018) Impact of meal fatty acid composition on postprandial lipaemia, vascular function and blood pressure in postmenopausal women. Nutrition Research Reviews, 31 (2). pp. 193-203. ISSN 0954-4224 doi: https://doi.org/10.1017/S0954422418000033

Roche, D. B., Buenavista, M. T. and McGuffin, L. J. (2018) Protein structure prediction and structural annotation of proteomes. In: Encyclopedia of Biophysics. Springer. doi: https://doi.org/10.1007/978-3-642-35943-9_418-1

S

Salamah, M. F., Ravishankar, D., Kodji, X., Moraes, L. A., Williams, H. F., Vallance, T. M., Albadawi, D. A., Vaiyapuri, R., Watson, K., Gibbins, J. M., Brain, S. D., Perretti, M. and Vaiyapuri, S. (2018) The endogenous antimicrobial cathelicidin LL37 induces platelet activation and augments thrombus formation. Blood Advances, 2 (21). pp. 2973-2985. ISSN 2473-9529 doi: https://doi.org/10.1182/bloodadvances.2018021758

Sasikumar, P., AlOuda, K. S., Kaiser, W. J., Holbrook, L. M., Kriek, N., Unsworth, A. J., Bye, A. P., Sage, T., Ushioda, R. W., Nagata, K., Farndale, R. W. and Gibbins, J. M. (2018) The chaperone protein HSP47: a platelet collagen binding protein that contributes to thrombosis and haemostasis. Journal of Thrombosis and Haemostasis, 16 (5). pp. 946-959. ISSN 1538-7933 doi: https://doi.org/10.1111/jth.13998

Snowden, T. J., van der Graaf, P. H. and Tindall, M. J. (2018) Model reduction in mathematical pharmacology: integration, reduction and linking of PBPK and systems biology models. Journal of Pharmacokinetics and Pharmacodynamics, 45 (4). pp. 537-555. ISSN 1573-8744 doi: https://doi.org/10.1007/s10928-018-9584-y

Stefanini, L., Lee, R. H., Paul, D. S., O'Shaughnessy, E. C., Ghalloussi, D., Jones, C. I., Boulaftali, Y., Poe, K. O., Piatt, R., Kechele, D. O., Caron, K. M., Hahn, K. M., Gibbins, J. M. and Bergmeier, W. (2018) Functional redundancy between RAP1 isoforms in murine platelet production and function. Blood, 132 (18). pp. 1951-1962. ISSN 0006-4971 doi: https://doi.org/10.1182/blood-2018-03-838714

T

Tindall, M. J. (2018) System insights into hemostasis: open questions and the role of mathematical modelling: comment on “Modeling thrombosis in silico: Frontiers, challenges, unresolved problems and milestones” by A.V. Belyaev et al. Physics of Life Reviews, 26-27. pp. 106-107. ISSN 1571-0645 doi: https://doi.org/10.1016/j.plrev.2018.06.011

U

Unsworth, A. J., Flora, G. D. and Gibbins, J. M. (2018) Non-genomic effects of nuclear receptors: insights from the anucleate platelet. Cardiovascular Research, 114 (5). pp. 645-655. ISSN 0008-6363 doi: https://doi.org/10.1093/cvr/cvy044

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