Article

Ahmad, F. and Leake, D. ORCID: https://orcid.org/0000-0002-1742-6134 (2018) Antioxidants inhibit low density lipoprotein oxidation less at lysosomal pH: a possible explanation as to why the clinical trials of antioxidants might have failed. Chemistry and Physics of Lipids, 213. pp. 13-24. ISSN 0009-3084 doi: https://doi.org/10.1016/j.chemphyslip.2018.03.001

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Bye, A. P. ORCID: https://orcid.org/0000-0002-2061-2253 and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 (2018) Move along, nothing to see here: Btk inhibitors stop platelets sticking to plaques. Journal of Thrombosis and Haemostasis, 16 (8). pp. 1461-1463. ISSN 1538-7933 doi: https://doi.org/10.1111/jth.14201

Dede, E., Tindall, M. J., Cherrie, J. W., Hankin, S. and Collins, C. (2018) Physiologically-based pharmacokinetic and toxicokinetic models for estimating human exposure to five toxic elements through oral ingestion. Environmental toxicology and pharmacology, 57. pp. 104-114. ISSN 1872-7077 doi: https://doi.org/10.1016/j.etap.2017.12.003

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Elofsson, A., Joo, K., Keasar, C., Lee, J., Maghrabi, A. H. A., Manavalan, B., McGuffin, L. J. ORCID: https://orcid.org/0000-0003-4501-4767, Ménendez Hurtado, D., Mirabello, C., Pilstål, R., Sidi, T., Uziela, K. and Wallner, B. (2018) Methods for estimation of model accuracy in CASP12. Proteins: Structure, Function, and Bioinformatics, 86. pp. 361-373. ISSN 1097-0134 doi: https://doi.org/10.1002/prot.25395

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Fekete, A. A., Giromini, C., Chatzidiakou, Y., Givens, D. I. ORCID: https://orcid.org/0000-0002-6754-6935 and Lovegrove, J. A. ORCID: https://orcid.org/0000-0001-7633-9455 (2018) Whey protein lowers systolic blood pressure and Ca-caseinate reduces serum TAG after a high-fat meal in mildly hypertensive adults. Scientific Reports, 8. 5026. ISSN 2045-2322 doi: https://doi.org/10.1038/s41598-018-23333-2

Fuentos, E., Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352, Holbrook, L. M. and Palomo, I. (2018) NADPH oxidase 2 (NOX2): a key target of oxidative stress-mediated platelet activation and thrombosis. Trends in Cardiovascular Medicine, 28 (7). pp. 429-434. ISSN 1050-1738 doi: https://doi.org/10.1016/j.tcm.2018.03.001

Griffin, B. A. and Lovegrove, J. A. ORCID: https://orcid.org/0000-0001-7633-9455 (2018) Butter increases high-density lipoprotein functional capacity: is this compensation for its adverse effect on serum low-density lipoprotein cholesterol? Journal of Nutrition, 148 (7). pp. 1069-1070. ISSN 1541-6100 doi: https://doi.org/10.1093/jn/nxy086

Griffin, B. A., Walker, C. G., Jebb, S. A., Moore, C., Frost, G. S., Goff, L., Sanders, T. A. B., Lewis, F., Griffin, M., Gitau, R. and Lovegrove, J. A. ORCID: https://orcid.org/0000-0001-7633-9455 (2018) APOE4 genotype exerts greater benefit in lowering plasma cholesterol and apolipoprotein B than wild type (E3/E3), after replacement of dietary saturated fats with low glycaemic index carbohydrates. Nutrients, 10 (10). 1524. ISSN 2072-6643 doi: https://doi.org/10.3390/nu10101524

Guo, J., Jackson, K. G. ORCID: https://orcid.org/0000-0002-0070-3203, Givens, D. I. ORCID: https://orcid.org/0000-0002-6754-6935 and Lovegrove, J. A. ORCID: https://orcid.org/0000-0001-7633-9455 (2018) Reply to TR Hill and I Kyriazakis. Journal of Nutrition, 148 (4). p. 665. ISSN 1541-6100 doi: https://doi.org/10.1093/jn/nxy010

Keasar, C., McGuffin, L. J. ORCID: https://orcid.org/0000-0003-4501-4767, Wallner, B., Chopra, G., Adhikari, B., Bhattacharya, D., Blake, L., Bortot, L. O., Cao, R., Dhanasekaran, B. K., Dimas, I., Faccioli, R. A., Faraggi, E., Ganzynkowicz, R., Ghosh, S., Ghosh, S., Giełdoń, A., Golon, L., He, Y., Heo, L., Hou, J., Khan, M., Khatib, F., Khoury, G. A., Kieslich, C., Kim, D. E., Krupa, P., Lee, G. R., Li, H., Li, J., Lipska, A., Liwo, A., Maghrabi, A. H. A., Mirdita, M., Mirzaei, S., Mozolewska, M. A., Onel, M., Ovchinnikov, S., Shah, A., Shah, U., Sidi, T., Sieradzan, A. K., Ślusarz, M., Ślusarz, R., Smadbeck, J., Tamamis, P., Trieber, N., Wirecki, T., Yin, Y., Zhang, Y., Bacardit, J., Baranowski, M., Chapman, N., Cooper, S., Defelicibus, A., Flatten, J., Koepnick, B., Popović, Z., Zaborowski, B., Baker, D., Cheng, J., Czaplewski, C., Delbem, A. C. B., Floudas, C., Kloczkowski, A., Ołdziej, S., Levitt, M., Scheraga, H., Seok, C., Söding, J., Vishveshwara, S., Xu, D. and Crivelli, S. N. (2018) An analysis and evaluation of the WeFold collaborative for protein structure prediction and its pipelines in CASP11 and CASP12. Scientific Reports, 8 (1). 9939. ISSN 2045-2322 doi: https://doi.org/10.1038/s41598-018-26812-8

Limbu, R., Cottrell, G. S. ORCID: https://orcid.org/0000-0001-9098-7627 and McNeish, A. J. (2018) Characterisation of the vasodilation effects of DHA and EPA, n-3 PUFAs (fish oils), in rat aorta and mesenteric resistance arteries. PLoS ONE, 13 (2). e0192484. ISSN 1932-6203 doi: https://doi.org/10.1371/journal.pone.0192484

Macready, A. ORCID: https://orcid.org/0000-0003-0368-9336, Fallaize, R., Butler, L. T., Ellis, J. A., Kuznesof, S., Frewer, L. J., Celis-Morales, C., Livingstone, K. M., Araújo-Soares, V., Fischer, A. R. H., Stewart-Knox, B. J., Mathers, J. C. and Lovegrove, J. A. ORCID: https://orcid.org/0000-0001-7633-9455 (2018) Application of behavior change techniques in a personalized nutrition Electronic Health intervention study: protocol for the web-based Food4Me randomized controlled trial. JMIR Research Protocols, 7 (4). e87. ISSN 1929-0748 doi: https://doi.org/10.2196/resprot.8703

Maldonado, E. M., Fisher, C. P., Mazzatti, D. J., Barber, A. L., Tindall, M. J., Plant, N. J., Kierzek, A. M. and Moore, J. B. (2018) Multi-scale, whole-system models of liver metabolic adaptation to fat and sugar in non-alcoholic fatty liver disease. NPJ Systems Biology and Applications, 4. 33. ISSN 2056-7189 doi: https://doi.org/10.1038/s41540-018-0070-3

McGuffin, L. ORCID: https://orcid.org/0000-0003-4501-4767, Shuid, A. N., Kempster, R., Maghrabi, A. H.A., Nealon, J. O., Salehe, B. R., Atkins, J. D. and Roche, D. B. (2018) Accurate template-based modeling in CASP12 using the IntFOLD4-TS, ModFOLD6, and ReFOLD methods. Proteins: Structure, Function, and Bioinformatics, 86. pp. 335-344. ISSN 0887-3585 doi: https://doi.org/10.1002/prot.25360

Molica, F., Figueroa, X. F., Kwak, B. R., Isakson, B. E. and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 (2018) Connexins and pannexins in vascular function and disease. International Journal of Molecular Sciences, 19 (6). 1663. ISSN 1422-0067 doi: https://doi.org/10.3390/ijms19061663

Ojo, O. O. and Leake, D. S. ORCID: https://orcid.org/0000-0002-1742-6134 (2018) Low density lipoprotein oxidation by ferritin at lysosomal pH. Chemistry and Physics of Lipids, 217. pp. 51-57. ISSN 0009-3084 doi: https://doi.org/10.1016/j.chemphyslip.2018.09.016

Palmer, C., Peri, F., Neumann, F., Ahmad, F., Leake, D. S. ORCID: https://orcid.org/0000-0002-1742-6134 and Pirianov, G. (2018) The synthetic glycolipid-based TLR4 antagonist FP7 negatively regulates in vitro and in vivo haematopoietic and non-haematopoietic vascular TLR4 signalling. Innate Immunity, 24 (7). pp. 411-421. ISSN 1753-4267 doi: https://doi.org/10.1177/1753425918798904

Pool, F., Currie, R., Sweby, P. K. ORCID: https://orcid.org/0009-0003-8488-0251, Salazar, J. D. and Tindall, M. J. (2018) A mathematical model of the mevalonate cholesterol biosynthesis pathway. Journal of Theoretical Biology, 443. pp. 157-176. ISSN 0022-5193 doi: https://doi.org/10.1016/j.jtbi.2017.12.023

Pool, F., Sweby, P. K. ORCID: https://orcid.org/0009-0003-8488-0251 and Tindall, M. J. (2018) An integrated mathematical model of cellular cholesterol biosynthesis and lipoprotein metabolism. Processes, 6 (8). 134. ISSN 2227-9717 doi: https://doi.org/10.3390/pr6080134

Rathnayake, K. M., Weech, M. ORCID: https://orcid.org/0000-0003-1738-877X, Jackson, K. G. ORCID: https://orcid.org/0000-0002-0070-3203 and Lovegrove, J. A. ORCID: https://orcid.org/0000-0001-7633-9455 (2018) Meal fatty acids have differential effects on postprandial blood pressure and biomarkers of endothelial function but not vascular reactivity in postmenopausal women in the Randomized Controlled Dietary Intervention and VAScular function (DIVAS)-2 Study. Journal of Nutrition, 148 (3). pp. 348-357. ISSN 1541-6100 doi: https://doi.org/10.1093/jn/nxx042

Rathnayake, K., Weech, M. ORCID: https://orcid.org/0000-0003-1738-877X, Jackson, K. ORCID: https://orcid.org/0000-0002-0070-3203 and Lovegrove, J. ORCID: https://orcid.org/0000-0001-7633-9455 (2018) Impact of meal fatty acid composition on postprandial lipaemia, vascular function and blood pressure in postmenopausal women. Nutrition Research Reviews, 31 (2). pp. 193-203. ISSN 0954-4224 doi: https://doi.org/10.1017/S0954422418000033

Salamah, M. F., Ravishankar, D., Kodji, X., Moraes, L. A., Williams, H. F., Vallance, T. M., Albadawi, D. A., Vaiyapuri, R., Watson, K. ORCID: https://orcid.org/0000-0002-9987-8539, Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352, Brain, S. D., Perretti, M. and Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517 (2018) The endogenous antimicrobial cathelicidin LL37 induces platelet activation and augments thrombus formation. Blood Advances, 2 (21). pp. 2973-2985. ISSN 2473-9529 doi: https://doi.org/10.1182/bloodadvances.2018021758

Sasikumar, P., AlOuda, K. S., Kaiser, W. J., Holbrook, L. M., Kriek, N., Unsworth, A. J., Bye, A. P. ORCID: https://orcid.org/0000-0002-2061-2253, Sage, T., Ushioda, R. W., Nagata, K., Farndale, R. W. and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 (2018) The chaperone protein HSP47: a platelet collagen binding protein that contributes to thrombosis and haemostasis. Journal of Thrombosis and Haemostasis, 16 (5). pp. 946-959. ISSN 1538-7933 doi: https://doi.org/10.1111/jth.13998

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Stefanini, L., Lee, R. H., Paul, D. S., O'Shaughnessy, E. C., Ghalloussi, D., Jones, C. I. ORCID: https://orcid.org/0000-0001-7537-1509, Boulaftali, Y., Poe, K. O., Piatt, R., Kechele, D. O., Caron, K. M., Hahn, K. M., Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 and Bergmeier, W. (2018) Functional redundancy between RAP1 isoforms in murine platelet production and function. Blood, 132 (18). pp. 1951-1962. ISSN 0006-4971 doi: https://doi.org/10.1182/blood-2018-03-838714

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Book or Report Section

Bye, A. P. ORCID: https://orcid.org/0000-0002-2061-2253, Unsworth, A. J. and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 (2018) Screening and high-throughput platelet assays. In: Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 and Mahaut-Smith, M. (eds.) Platelets and Megakaryocytes: Volume 4, Advanced Protocols and Perspectives. Humana Press, New York, pp. 81-94. ISBN 9781493985845 doi: https://doi.org/10.1007/978-1-4939-8585-2_5

Dunster, J. L. ORCID: https://orcid.org/0000-0001-8986-4902, Panteleev, M. A., Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 and Sveshnikova, A. N. (2018) Mathematical techniques for understanding platelet regulation and the development of new pharmacological approaches. In: Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 and Mahaut-Smith, M. (eds.) Platelets and Megakaryocytes: Volume 4, Advanced Protocols and Perspectives. Methods in Molecular Biology, 1812. Humana Press, New York, pp. 255-279. ISBN 9781493985845 doi: https://doi.org/10.1007/978-1-4939-8585-2_15

Dustin, M. L. and Pollitt, A. Y. ORCID: https://orcid.org/0000-0001-8706-5154 (2018) The study of platelet receptors using artificial lipid bilayers. In: Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 and Mahaut-Smith, M. (eds.) Platelets and Megakaryocytes: Volume 4, Advanced Protocols and Perspectives. Methods in Molecular Biology, 1812. Humana Press, New York, pp. 127-137. ISBN 9781493985845 doi: https://doi.org/10.1007/978-1-4939-8585-2_8

Fallaize, R. and Lovegrove, J. ORCID: https://orcid.org/0000-0001-7633-9455 (2018) Nutrition in marginalised groups. In: Bonner, A. (ed.) Social Determinants of Health: An Interdisciplinary Approach to Social Inequality and Well-Being. Policy Press, Bristol, pp. 41-53. ISBN 9781447336860

Lovegrove, J. ORCID: https://orcid.org/0000-0001-7633-9455 (2018) Hugh Macdonald Sinclair. In: 30-second Nutrition. 30 Second. Ivy Press, London, United Kingdom, pp. 130-131. ISBN 9781782405535

Lovegrove, J. ORCID: https://orcid.org/0000-0001-7633-9455 (2018) Milk and dairy. In: 30-Second Nutrition. 30 Second. Ivy Press, London, United Kingdom, pp. 60-61. ISBN 9781782405535

Lovegrove, J. ORCID: https://orcid.org/0000-0001-7633-9455 and Griffin, B. (2018) Dietary fats and heart disease. In: 30-Second Nutrition. 30 Second. Ivy Press, London, United Kingdom, pp. 100-101. ISBN 9781782405535

Mazet, F. and Fry, M. J. (2018) Precise quantification of platelet proteins and their phosphorylation states. In: Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 and Mahaut-Smith, M. (eds.) Platelets and Megakaryocytes: Volume 4, Advanced Protocols and Perspectives. Humana Press, New York, pp. 113-125. ISBN 9781493985845 doi: https://doi.org/10.1007/978-1-4939-8585-2_7

Roche, D. B., Buenavista, M. T. and McGuffin, L. J. ORCID: https://orcid.org/0000-0003-4501-4767 (2018) Protein structure prediction and structural annotation of proteomes. In: Encyclopedia of Biophysics. Springer. doi: https://doi.org/10.1007/978-3-642-35943-9_418-1

Book

Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 and Mahaut-Smith, M., eds. (2018) Platelets and Megakaryocytes. Volume 4, Advanced Protocols and Perspectives. Methods in Molecular Biology, 1812. Humana Press, pp304. ISBN 9781493985845 doi: https://doi.org/10.1007/978-1-4939-8585-2

Lovegrove, J. ORCID: https://orcid.org/0000-0001-7633-9455 (2018) 30-Second Nutrition. 30 Second. Ivy Press, London, pp160. ISBN 9781782405535

Thesis

Flora, G. D. (2018) Non-genomic effects of the Pregnane X Receptor (PXR) and Retinoid X Receptor (RXR) in platelets. PhD thesis, University of Reading. doi: https://doi.org/10.17864/1926.80709