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Items where Division is "Institute for Cardiovascular and Metabolic Research (ICMR)" and Year is 2019

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Number of items: 23.

A

Adiyaman, R. and McGuffin, L. J. ORCID: https://orcid.org/0000-0003-4501-4767 (2019) Methods for the refinement of protein structure 3D models. International Journal of Molecular Sciences, 20 (9). 2301. ISSN 1422-0067 doi: https://doi.org/10.3390/ijms20092301

Ahmad, F. and Leake, D. S. ORCID: https://orcid.org/0000-0002-1742-6134 (2019) Lysosomal oxidation of LDL alters lysosomal pH, induces senescence and increases secretion of pro-inflammatory cytokines in human macrophages. Journal of Lipid Research, 60. pp. 98-110. ISSN 1539-7262 doi: https://doi.org/10.1194/jlr.M088245

AlOuda, S. K. (2019) Role of the collagen molecular chaperone heat shock protein (HSP) 47 in platelet-collagen interaction. PhD thesis, University of Reading. doi: https://doi.org/10.48683/1926.00085394

C

Celis-Morales, C., Livingstone, K. M., Petermann, F., Navas-Carretero, S., San-Cristobal, R., O’Donovan, C. B., Moschonis, G., Manios, Y., Traczyk, I., Drevon, C. A., Daniel, H., Marsaux, C. F., Saris, W. H., Fallaize, R., Macready, A. L. ORCID: https://orcid.org/0000-0003-0368-9336, Lovegrove, J. A. ORCID: https://orcid.org/0000-0001-7633-9455, Gibney, M., Gibney, E. R., Walsh, M., Brennan, L., Martinez, A. and Mathers, J. C. (2019) Frequent nutritional feedback, personalized advice, and behavioral changes: findings from the European Food4Me internet-based RCT. American Journal of Preventive Medicine, 57 (2). pp. 209-219. ISSN 0749-3797 doi: https://doi.org/10.1016/j.amepre.2019.03.024

Cheng, J., Choe, M.‐H., Elofsson, A., Han, K.‐S., Hou, J., Maghrabi, A. H. A., McGuffin, L. J. ORCID: https://orcid.org/0000-0003-4501-4767, Menéndez‐Hurtado, D., Olechnovič, K., Schwede, T., Studer, G., Uziela, K., Venclovas, Č. and Wallner, B. (2019) Estimation of model accuracy in CASP13. Proteins: Structure, Function, and Bioinformatics. ISSN 0887-3585 doi: https://doi.org/10.1002/prot.25767

Cucurull-Sanchez, L., Chappell, M. J., Chelliah, V., Amy Cheung, S. Y., Derks, G., Penney, M., Phipps, A., Malik-Sheriff, R. S., Timmis, J., Tindall, M. J., van der Graaf, P. H., Vicini, P. and Yates, J. W. T. (2019) Best practices to maximize the use and reuse of quantitative and systems pharmacology models: recommendations from the United Kingdom quantitative and systems pharmacology network. CPT: Pharmacometrics & Systems Pharmacology, 8 (5). pp. 259-272. ISSN 2163-8306 doi: https://doi.org/10.1002/psp4.12381

F

Fan, L. M., Geng, L., Cahill-Smith, S., Liu, F., Douglas, G., Mckenzie, C.-A., Smith, C., Brooks, G., Channon, K. M. and Li, J.-m. ORCID: https://orcid.org/0000-0002-3294-3818 (2019) Nox2 contributes to age-related oxidative damage to neurons and the cerebral vasculature. The Journal of Clinical Investigation, 129 (8). pp. 3374-3386. ISSN 1558-8238 doi: https://doi.org/10.1172/JCI125173

Flora, G. D., Sahli, K. A., Sasikumar, P., Holbrook, L.-M., Stainer, A. R., Alouda, S. K., Crescente, M., Sage, T., Unsworth, A. J. and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 (2019) Non-genomic effects of the Pregnane X Receptor negatively regulate platelet functions, thrombosis and haemostasis. Scientific Reports, 9 (1). 17210. ISSN 2045-2322 doi: https://doi.org/10.1038/s41598-019-53218-x

H

Hobbs, D. A., Givens, D. I. ORCID: https://orcid.org/0000-0002-6754-6935 and Lovegrove, J. A. ORCID: https://orcid.org/0000-0001-7633-9455 (2019) Yogurt consumption is associated with higher nutrient intake, diet quality and favourable metabolic profile in children: a cross-sectional analysis using data from years 1–4 of the National diet and Nutrition Survey, UK. European Journal of Nutrition, 58 (1). pp. 409-422. ISSN 1436-6215 doi: https://doi.org/10.1007/s00394-017-1605-x

M

Macwan, A. S., Boknas, N., Ntzouni, M. P., Ramstrom, S., Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352, Faxalv, L. and Lindahl, T. L. (2019) Gradient-dependent inhibition of stimulatory signaling from platelet G protein-coupled receptors. Haematologica, 104 (7). pp. 1482-1492. ISSN 1592-8721 doi: https://doi.org/10.3324/haematol.2018.205815

McGuffin, L. J. ORCID: https://orcid.org/0000-0003-4501-4767, Adiyaman, R., Maghrabi, A. H. A., Shuid, A. N., Brackenridge, D. A., Nealon, J. O. and Philomina, L. S. (2019) IntFOLD: an integrated web resource for high performance protein structure and function prediction. Nucleic Acids Research. gkz322. ISSN 1362-4962 doi: https://doi.org/10.1093/nar/gkz322

Meijles, D. N., Zoumpoulidou, G., Markou, T., Rostron, K. A., Patel, R., Lay, K., Handa, B. S., Wong, B., Sugden, P. H. and Clerk, A. ORCID: https://orcid.org/0000-0002-5658-0708 (2019) The cardiomyocyte "redox rheostat": Redox signalling via the AMPK-mTOR axis and regulation of gene and protein expression balancing survival and death. Journal of molecular and cellular cardiology, 129. pp. 118-129. ISSN 1095-8584 doi: https://doi.org/10.1016/j.yjmcc.2019.02.006

N

Navas-Carretero, S., San-Cristobal, R., Livingstone, K. M., Celis-Morales, C., Marsaux, C. F., Macready, A. L. ORCID: https://orcid.org/0000-0003-0368-9336, Fallaize, R., O’Donovan, C. B., Forster, H., Woolhead, C., Moschonis, G., Lambrinou, C. P., Jarosz, M., Manios, Y., Daniel, H., Gibney, E. R., Brennan, L., Walsh, M. C., Drevon, C. A., Gibney, M., Saris, W. H. M., Lovegrove, J. A. ORCID: https://orcid.org/0000-0001-7633-9455, Mathers, J. C. and Martinez, J. A. (2019) Higher vegetable protein consumption, assessed by an isoenergetic macronutrient exchange model, is associated with a lower presence of overweight and obesity in the web-based Food4me European study. International Journal of Food Sciences and Nutrition, 70 (2). pp. 240-253. ISSN 1465-3478 doi: https://doi.org/10.1080/09637486.2018.1492524

R

Rathnayake, K. M., Weech, M. ORCID: https://orcid.org/0000-0003-1738-877X, Jackson, K. G. ORCID: https://orcid.org/0000-0002-0070-3203 and Lovegrove, J. A. ORCID: https://orcid.org/0000-0001-7633-9455 (2019) Impact of the apolipoprotein E (epsilon) genotype on cardiometabolic risk markers and responsiveness to acute and chronic dietary fat manipulation. Nutrients, 11 (9). 2044. ISSN 2072-6643 doi: https://doi.org/10.3390/nu11092044

S

Salamah, M. (2019) The role of formyl peptide receptors in the regulation of platelet function. PhD thesis, University of Reading. doi: https://doi.org/10.48683/1926.00084407

Stainer, A., Sasikumar, P., Bye, A. ORCID: https://orcid.org/0000-0002-2061-2253, Unsworth, A., Holbrook, L., Tindall, M., Lovegrove, J. ORCID: https://orcid.org/0000-0001-7633-9455 and Gibbins, J. ORCID: https://orcid.org/0000-0002-0372-5352 (2019) Quercetin and its methylated metabolites possess anti-thrombotic properties that interact with aspirin to enhance its anti-platelet effects. TH Open, 3 (3). e244-e258. ISSN 2512-9465 doi: https://doi.org/10.1055/s-0039-1694028

Stainer, A. R., Sasikumar, P., Bye, A. P. ORCID: https://orcid.org/0000-0002-2061-2253, Unsworth, A. P., Holbrook, L. M., Tindall, M., Lovegrove, J. A. ORCID: https://orcid.org/0000-0001-7633-9455 and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 (2019) The metabolites of the dietary flavonoid quercetin possess potent antithrombotic activity, and interact with aspirin to enhance antiplatelet effects. TH Open, 3 (3). e244-e258. ISSN 2512-9465 doi: https://doi.org/10.1055/s-0039-1694028

U

Unsworth, A. J., Bombik, I., Pinto-Fernandez, A., McGouran, J. F., Konietzny, R., Zahedi, R. P., Watson, S. P., Kessler, B. M. and Pears, C. J. (2019) Human platelet protein ubiquitylation and changes following GPVI activation. Thrombosis and Haemostasis, 119 (1). pp. 104-116. ISSN 0340-6245 doi: https://doi.org/10.1055/s-0038-1676344

Unsworth, A. J., Bye, A. P. ORCID: https://orcid.org/0000-0002-2061-2253, Kriek, N., Sage, T., Osborne, A. A., Donaghy, D. and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 (2019) Cobimetinib and trametinib inhibit platelet MEK but do not cause platelet dysfunction. Platelets, 30 (6). pp. 762-772. ISSN 0953-7104 doi: https://doi.org/10.1080/09537104.2018.1514107

W

Ward, J. P., Franks, S. J., Tindall, M. J., King, J. R., Curtis, A. and Evans, G. S. (2019) Mathematical modelling of contact dermatitis from nickel and chromium. Journal of Mathematical Biology, 79 (2). pp. 595-630. ISSN 0303-6812 doi: https://doi.org/10.1007/s00285-019-01371-2

Wen, Y., Ahmad, F., Mohri, Z., Weinberg, P. D. and Leake, D. S. ORCID: https://orcid.org/0000-0002-1742-6134 (2019) Cysteamine inhibits lysosomal oxidation of low density lipoprotein in human macrophages and reduces atherosclerosis in mice. Atherosclerosis, 291. pp. 9-18. ISSN 0021-9150 doi: https://doi.org/10.1016/j.atherosclerosis.2019.09.019

Williams, H., Mellows, B., Mitchell, R., Sfyri, P., Layfield, H., Salamah, M., Vaiyapuri, R., Collins-Hooper, H., Bicknell, A., Matsakas, A., Patel, K. and Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517 (2019) Mechanisms underpinning the permanent muscle damage induced by snake venom metalloprotease. PLoS Neglected Tropical Diseases, 13 (1). e0007041. ISSN 1935-2735 doi: https://doi.org/10.1371/journal.pntd.0007041

Z

Zhou, N., Jiang, Y., Bergquist, T. R., Lee, A. J., Kacsoh, B. Z., Crocker, A. W., Lewis, K. A., Georghiou, G., Nguyen, H. N., Hamid, M. N., Davis, L., Dogan, T., Atalay, V., Rifaioglu, A. S., Dalkiran, A., Cetin-Atalay, R., Zhang, C., Hurto, R. L., Freddolino, P. L., Zhang, Y., Bhat, P., Supek, F., Fernández, J. M., Gemovic, B., Perovic, V. R., Davidović, R. S., Sumonja, N., Veljkovic, N., Asgari, E., Mofrad, M. R. K., Profiti, G., Savojardo, C., Martelli, P. L., Casadio, R., Boecker, F., Kahanda, I., Thurlby, N., McHardy, A. C., Renaux, A., Saidi, R., Gough, J., Freitas, A. A., Antczak, M., Fabris, F., Wass, M. N., Hou, J., Cheng, J., Hou, J., Wang, Z., Romero, A. E., Paccanaro, A., Yang, H., Goldberg, T., Zhao, C., Holm, L., Törönen, P., Medlar, A. J., Zosa, E., Borukhov, I., Novikov, I., Wilkins, A., Lichtarge, O., Chi, P.-H., Tseng, W.-C., Linial, M., Rose, P. W., Dessimoz, C., Vidulin, V., Dzeroski, S., Sillitoe, I., Das, S., Lees, J. G., Jones, D. T., Wan, C., Cozzetto, D., Fa, R., Torres, M., Vesztrocy, A. W., Rodriguez, J. M., Tress, M. L., Frasca, M., Notaro, M., Grossi, G., Petrini, A., Re, M., Valentini, G., Mesiti, M., Roche, D. B., Reeb, J., Ritchie, D. W., Aridhi, S., Alborzi, S. Z., Devignes, M.-D., Emily Koo, D. C., Bonneau, R., Gligorijević, V., Barot, M., Fang, H., Toppo, S., Lavezzo, E., Falda, M., Berselli, M., Tosatto, S. C. E., Carraro, M., Piovesan, D., Rehman, H. U., Mao, Q., Zhang, S., Vucetic, S., Black, G. S., Jo, D., Larsen, D. J., Omdahl, A. R., Sagers, L. W., Suh, E., Dayton, J. B., McGuffin, L. ORCID: https://orcid.org/0000-0003-4501-4767, Brackenridge, D. A., Babbitt, P. C., Yunes, J. M., Fontana, P., Zhang, F., Zhu, S., You, R., Zhang, Z., Dai, S., Yao, S., Tian, W., Cao, R., Chandler, C., Amezola, M., Johnson, D., Chang, J.-M., Liao, W.-H., Liu, Y.-W., Pascarelli, S., Frank, Y., Hoehndorf, R., Kulmanov, M., Boudellioua, I., Politano, G., Di Carlo, S., Benso, A., Hakala, K., Ginter, F., Mehryary, F., Kaewphan, S., Björne, J., Moen, H., Tolvanen, M. E. E., Salakoski, T., Kihara, D., Jain, A., Šmuc, T., Altenhoff, A., Ben-Hur, A., Rost, B., Brenner, S. E., Orengo, C. A., Jeffery, C. J., Bosco, G., Hogan, D. A., Martin, M. J., O’Donovan, C., Mooney, S. D., Greene, C. S., Radivojac, P. and Friedberg, I. (2019) The CAFA challenge reports improved protein function prediction and new functional annotations for hundreds of genes through experimental screens. Genome Biology, 20 (1). 244. ISSN 1474-760X doi: https://doi.org/10.1186/s13059-019-1835-8

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