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Items where Division is "Institute for Cardiovascular and Metabolic Research (ICMR)" and Year is 2021

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Number of items: 30.

A

Adiyaman, R. and McGuffin, L. ORCID: https://orcid.org/0000-0003-4501-4767 (2021) ReFOLD3: refinement of 3D protein models with gradual restraints based on predicted local quality and residue contacts. Nucleic Acids Research. ISSN 1362-4962 doi: https://doi.org/10.1093/nar/gkab300

Ahmad, F., Mitchell, R., Houben, T., Palo, A., Yasdati, T., Parnell, A., Patel, K., Shiri-Sverdlov, R. and Leake, D. (2021) Cysteamine decreases low density lipoprotein oxidation, causes regression of atherosclerosis and improves liver and muscle function in LDL receptor deficient mice. JAHA: Journal of the American Heart Association. ISSN 2047-9980 doi: https://doi.org/10.1161/JAHA.120.017524

B

Brackenridge, D. and McGuffin, L. ORCID: https://orcid.org/0000-0003-4501-4767 (2021) Proteins and their interacting partners: an introduction to protein–ligand binding site prediction methods with a focus on FunFOLD3. In: Cacace, A., Hickey, C. and Bekes, M. (eds.) Targeted Protein Degradation: Methods and Protocols. Methods in Molecular Biology, 2365. Springer. ISBN 9781071616642 doi: https://doi.org/10.1007/978-1-0716-1665-9 (In Press)

Bye, A. P., Hoepel, W., Mitchell, J. L., Jegouic, S. M., Loureiro, S., Sage, T., Vidarsson, G., Nouta, J., Wuhrer, M., de Taeye, S. W., van Gils, M., Kriek, N., Cooper, N., Jones, I. ORCID: https://orcid.org/0000-0002-7738-2516, den Dunnen, J. and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 (2021) Aberrant glycosylation of anti-SARS-CoV-2 spike IgG is a pro-thrombotic stimulus for platelets. Blood. ISSN 0006-4971 doi: https://doi.org/10.1182/blood.2021011871 (In Press)

C

Cai, H., Sasikumar, P., Little, G., Bihan, D., Hamaia, S. W., Zhou, A., Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 and Farndale, R. W. (2021) Identification of HSP47 binding site on native collagen and its implications on the development of HSP47 inhibitors. Biomolecules, 11 (7). 983. ISSN 2218-273X doi: https://doi.org/10.3390/biom11070983

D

Derrick, D. J. A., Wolton, K., Currie, R. A. and Tindall, M. J. (2021) A mathematical model of the role of aggregation in sonic hedgehog signalling. PLoS computational biology, 17 (2). e1008562. ISSN 1553-7358 doi: https://doi.org/10.1371/journal.pcbi.1008562

Downes, K., Zhao, X., Gleadall, N. S., Antanavicius, N., McKinney, H., Kempster, C., Batista, J., Thomas, P. L., Cooper, M., Michael, J. V., Kreuzhuber, R., Wedderburn, K., Waller, K., Varney, B., Kriek, N., Ashford, S., Stirrups, K., Dunster, J., McKenzie, S., Ouwehand, W. H., Gibbins, J. ORCID: https://orcid.org/0000-0002-0372-5352, Yang, J., Astle, W. J. and Ma, P. (2021) G protein-coupled receptor kinase 5 regulates thrombin signaling in platelets via PAR-1. Blood Advances. ISSN 2473-9529 (In Press)

Dunster, J., Bye, A., Kriek, N., Sage, T., Mitchell, J., Kempster, C., Batista, J., KcKinney, H., Thomas, P., Jones, C., Downes, K., Unsworth, A. and Gibbins, J. ORCID: https://orcid.org/0000-0002-0372-5352 (2021) Multi-parameter phenotyping of platelet reactivity for stratification of human cohorts. Blood Advances. ISSN 2473-9529 (In Press)

E

Edmunds, N. S. and McGuffin, L. J. ORCID: https://orcid.org/0000-0003-4501-4767 (2021) Computational methods for the elucidation of protein structure and interactions. In: Owens, R. J. (ed.) Methods Molecular Biology: Structural Proteomics. Methods Molecular Biology, 2305. Springer Nature, pp. 23-52. ISBN 9781071614068 doi: https://doi.org/10.1007/978-1-0716-1406-8_2

F

Fuller, S. J., Edmunds, N. S., McGuffin, L. J. ORCID: https://orcid.org/0000-0003-4501-4767, Hardyman, M. A., Cull, J. J., Alharbi, H. O., Meijles, D. N., Sugden, P. H. and Clerk, A. ORCID: https://orcid.org/0000-0002-5658-0708 (2021) MAP4K4 expression in cardiomyocytes: multiple isoforms, multiple phosphorylations and interactions with striatins. Biochemical Journal, 478 (11). pp. 2121-2143. ISSN 0264-6021 doi: https://doi.org/10.1042/BCJ20210003

G

Gaspar, R. S., Ferreira, P., Mitchell, J. L., Pula, G. and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 (2021) Platelet-derived extracellular vesicles express NADPH oxidase-1 (Nox-1), generate superoxide and modulate platelet function. Free Radical Biology and Medicine, 165. pp. 395-400. ISSN 0891-5849 doi: https://doi.org/10.1016/j.freeradbiomed.2021.01.051

Gaspar, R. S., Mansilla, S., Vieira, V. A., da Silva, L. B., Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352, Castro, L., Trostchansky, A. and de A. Paes, A. M. (2021) The protein disulphide isomerase inhibitor CxxCpep modulates oxidative burst and mitochondrial function in platelets. Free Radical Biology and Medicine, 172. pp. 668-674. ISSN 0891-5849 doi: https://doi.org/10.1016/j.freeradbiomed.2021.07.011

Griffin, B. A. and Lovegrove, J. A. (2021) Evidence for beneficial associations between Isoenergetic Macronutrient Exchanges and serum non-HDL cholesterol, a measure of all circulating atherogenic, apoB-containing lipoproteins. Journal of Nutrition, 151 (8). pp. 2096-2098. ISSN 1541-6100 doi: https://doi.org/10.1093/jn/nxab127

Griffin, B. A., Mensink, R. P. and Lovegrove, J. A. (2021) Does variation in serum LDL-cholesterol response to dietary fatty acids help explain the controversy over fat quality and cardiovascular disease risk? Atherosclerosis, 328. pp. 108-113. ISSN 0021-9150 doi: https://doi.org/10.1016/j.atherosclerosis.2021.03.024

H

Holbrook, L.-M., Keeton, S. J., Sasikumar, P., Nock, S., Gelzinis, J., Brunt, E., Ryan, S., Pantos, M. M., Verbetsky, C. A., Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 and Kennedy, D. R. (2021) Zafirlukast is a broad-spectrum thiol isomerase inhibitor that inhibits thrombosis without altering bleeding times. British Journal of Pharmacology, 178 (3). pp. 550-563. ISSN 1476-5381 doi: https://doi.org/10.1111/bph.15291

Houben, T., Yadati, T., De Kruijf, R., Gijbels, M. J., Luiken, J., Van Zandvoort, M., Kapsokalyvas, D., Lütjohann, D., Westerterp, M., Plat, J., Leake, D. and Shiri-Sverdlov, R. (2021) Pro-inflammatory implications of 2-hydroxypropyl-β-cyclodextrin treatment. Frontiers in Immunology, 12. 716357. ISSN 1664-3224 doi: https://doi.org/10.3389/fimmu.2021.716357

K

Kryshtafovych, A. ORCID: https://orcid.org/0000-0001-5066-7178, Moult, J. ORCID: https://orcid.org/0000-0002-3012-2282, Billings, W. M., Della Corte, D. ORCID: https://orcid.org/0000-0002-8884-9724, Fidelis, K. ORCID: https://orcid.org/0000-0002-8061-412X, Kwon, S., Olechnovič, K. ORCID: https://orcid.org/0000-0003-4918-9505, Seok, C. ORCID: https://orcid.org/0000-0002-1419-9888, Venclovas, Č., Won, J., Adiyaman, R. and McGuffin, L. ORCID: https://orcid.org/0000-0003-4501-4767 (2021) Modeling SARS‐CoV2 proteins in the CASP ‐commons experiment. Proteins: Structure, Function, and Bioinformatics. ISSN 0887-3585 doi: https://doi.org/10.1002/prot.26231

L

Livingstone, K. M., Celis-Morales, C., Navas-Carretero, S., San-Cristobal, R., Forster, H., Woolhead, C., O’Donovan, C. B., Moschonis, G., Manios, Y., Traczyk, I., Gundersen, T. E., Drevon, C. A., Marsaux, C. F. M., Fallaize, R., Macready, A. L. ORCID: https://orcid.org/0000-0003-0368-9336, Daniel, H., Saris, W. H. M., Lovegrove, J. A., Gibney, M., Gibney, E. R., Walsh, M., Brennan, L., Martinez, J. A. and Mathers, J. C. (2021) Personalised nutrition advice reduces intake of discretionary foods and beverages: findings from the Food4Me randomised controlled trial. International Journal of Behavioral Nutrition and Physical Activity, 18 (1). 70. ISSN 1479-5868 doi: https://doi.org/10.1186/s12966-021-01136-5

M

Markey, O., Vasilopoulou, D., Kliem, K. E., Fagan, C. C., Grandison, A. S., Sutton, R., Humphries, D. J., Todd, S. ORCID: https://orcid.org/0000-0002-9981-923X, Jackson, K. G. ORCID: https://orcid.org/0000-0002-0070-3203, Givens, D. I. and Lovegrove, J. A. (2021) Postprandial fatty acid profile, but not cardiometabolic risk markers, is modulated by dairy fat manipulation in adults with moderate cardiovascular disease risk: the randomized controlled REplacement of SaturatEd fat in dairy on Total cholesterol (RESET) study. Journal of Nutrition, 151 (7). pp. 1755-1768. ISSN 1541-6100 doi: https://doi.org/10.1093/jn/nxab050

McGuffin, L. J. ORCID: https://orcid.org/0000-0003-4501-4767, Aldowsari, F. M. F., Alharbi, S. M. A. and Adiyaman, R. (2021) ModFOLD8: accurate global and local quality estimates for 3D protein models. Nucleic Acids Research. ISSN 1362-4962 doi: https://doi.org/10.1093/nar/gkab321

N

Navas-Carretero, S., San-Cristobal, R., Alvarez-Alvarez, I., Celis-Morales, C., Livingstone, K. M., O'Donovan, C. B., Mavrogianni, C., Lambrinou, C. P., Manios, Y., Traczyck, I., Drevon, C. A., Marsaux, C. F. M., Saris, W. H. M., Fallaize, R., Macready, A. L. ORCID: https://orcid.org/0000-0003-0368-9336, Lovegrove, J. A., Gundersen, T. E., Walsh, M., Brennan, L., Gibney, E. R., Gibney, M., Mathers, J. C. and Martinez, J. A. (2021) Interactions of carbohydrate intake and physical activity with regulatory genes affecting glycaemia: a Food4Me study analysis. Lifestyle Genomics. ISSN 2504-3188 doi: https://doi.org/10.1159/000515068

O

Ojo, O. O. and Leake, D. S. (2021) Vitamins E and C do not effectively inhibit low density lipoprotein oxidation by ferritin at lysosomal pH. Free Radical Research. ISSN 1071-5762 doi: https://doi.org/10.1080/10715762.2021.1964494

R

Rathnayake, K. M., Weech, M., Lovegrove, J. A. and Jackson, K. G. ORCID: https://orcid.org/0000-0002-0070-3203 (2021) Glu298Asp (rs1799983) polymorphism influences postprandial vascular reactivity and the insulin response to meals of varying fat composition in postmenopausal women: findings from the randomized, controlled DIVAS-2 study. Journal of Nutrition, 151 (4). pp. 848-856. ISSN 1541-6100 doi: https://doi.org/10.1093/jn/nxaa394

S

Sahli, K. A., Flora, G. D., Sasikumar, P., Maghrabi, A. H., Holbrook, L., AlOuda, S. K., Elgheznawy, A., Sage, T., Stainer, A. R., Adiyaman, R., AboHassan, M., Crescente, M., Kriek, N., Vaiyapuri, S., Bye, A. P., Unsworth, A. J., Jones, C. I., McGuffin, L. J. and Gibbins, J. M. (2021) Structural, functional and mechanistic insights uncover the fundamental role of orphan connexin-62 in platelets. Blood, 137 (6). pp. 830-843. ISSN 0006-4971 doi: https://doi.org/10.1182/blood.2019004575

Sellem, L., Srour, B., Jackson, K. G. ORCID: https://orcid.org/0000-0002-0070-3203, Hercberg, S., Galan, P., Kesse-Guyot, E., Julia, C., Fezeu, L., Deschasaux-Tanguy, M., Lovegrove, J. and Touvier, M. (2021) Consumption of dairy products and cardiovascular disease risk: results from the French prospective cohort NutriNet-Santé. British Journal of Nutrition. ISSN 0007-1145 doi: https://doi.org/10.1017/S0007114521001422

Simoes Gaspar, R. and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 (2021) Thiol isomerases orchestrate thrombosis and haemostasis. Antioxidants & Redox Signaling. ISSN 1523-0864 doi: https://doi.org/10.1089/ars.2021.0086

Simoes Gaspar, R., Sage, T., Little, G., Kriek, N., Pula, G. and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 (2021) Protein disulphide isomerase and NADPH oxidase 1 cooperate to control platelet function and are associated with cardiometabolic disease risk factors. Antioxidants, 10 (3). 497. ISSN 2076-3921 doi: https://doi.org/10.3390/antiox10030497

T

Taylor, K. A., Little, G. and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 (2021) Mind the gap: connexins and pannexins in platelet function. Platelets. ISSN 0953-7104

U

Unsworth, A. J., Bye, A. P., Sage, T., Gaspar, R. S., Eaton, N., Drew, C., Stainer, A., Kriek, N., Volberding, P. J., Hutchinson, J. L., Riley, R., Jones, S., Mundell, S. J., Cui, W., Falet, H. and Gibbins, J. M. (2021) Anti-platelet properties of Pim kinase inhibition is mediated through disruption of thromboxane A2 receptor signalling. Haematologica, 106 (7). ISSN 1592-8721 doi: https://doi.org/10.3324/haematol.2019.223529

V

Vavouraki, N. ORCID: https://orcid.org/0000-0003-2581-4935, Tomkins, J. E. ORCID: https://orcid.org/0000-0003-3010-6634, Kara, E. ORCID: https://orcid.org/0000-0001-5428-6743, Houlden, H., Hardy, J., Tindall, M. J., Lewis, P. A. ORCID: https://orcid.org/0000-0003-4537-0489 and Manzoni, C. (2021) Integrating protein networks and machine learning for disease stratification in the Hereditary Spastic Paraplegias. iScience, 24 (5). 102484. ISSN 2589-0042 doi: https://doi.org/10.1016/j.isci.2021.102484

This list was generated on Sun Oct 24 10:12:42 2021 UTC.

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