2025

Bye, A. P. ORCID: https://orcid.org/0000-0002-2061-2253, Kriek, N., Kempster, C., Dunster, J. L. ORCID: https://orcid.org/0000-0001-8986-4902, Mitchell, J. L., Sage, T., Rawlings, S., Diaz Alonso, M. V., Shpakova, V. ORCID: https://orcid.org/0000-0002-9304-7099, Whyte, A., Dymott, L., Mark, S., Brunton, M., Batista, J., McKinney, H., Thomas, P., Downes, K., Unsworth, A. J., Ruparelia, N., McKenna, C., Jones, C. I. ORCID: https://orcid.org/0000-0001-7537-1509 and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 (2025) TRIPLE score: GPVI and CD36 expression predict a prothrombotic platelet function phenotype. Circulation Research, 136 (4). pp. 439-441. ISSN 0009-7330 doi: 10.1161/CIRCRESAHA.124.325701

Kelly, E. F.A. ORCID: https://orcid.org/0000-0002-1014-5567, Guney-Coskun, M., Weech, M. ORCID: https://orcid.org/0000-0003-1738-877X, Fallaize, R., Hwang, F. ORCID: https://orcid.org/0000-0002-3243-3869 and Lovegrove, J. A. ORCID: https://orcid.org/0000-0001-7633-9455 (2025) Exploring the dietary changes and support required for healthy eating with female students at UK universities: Findings from focus group discussions. PLoS ONE, 20 (4). e0319388. ISSN 1932-6203 doi: 10.1371/journal.pone.0319388

Keovilay, J. A., Howard, K. C., Taylor, K. A. ORCID: https://orcid.org/0000-0002-4599-7727, Khan, S., Wurl, S. E., Szahaj, M. K., Sage, T., Chandrika, N. T., Hou, C., Tsodikov, O. V., Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352, Garneau-Tsodikova, S. and Kennedy, D. R. (2025) Development of zafirlukast analogues for improved anti-thrombotic activity through thiol isomerase inhibition. Arteriosclerosis Thrombosis and Vascular Biology. ISSN 1524-4636 doi: 10.1161/ATVBAHA.124.321579

Lovegrove, J. A. ORCID: https://orcid.org/0000-0001-7633-9455 (2025) Dietary fats and cardiometabolic health—from public health to personalised nutrition: ‘one for all’ and ‘all for one’. Nutrition Bulletin, 50 (1). pp. 132-141. ISSN 1471-9827 doi: 10.1111/nbu.12722

Wuni, R., Curi-Quinto, K., Liu, L., Espinoza, D., Aquino, A. I., del Valle-Mendoza, J., Aguilar-Luis, M. A., Murray, C., Nunes, R. ORCID: https://orcid.org/0000-0003-0829-4130, Methven, L., Lovegrove, J. A. ORCID: https://orcid.org/0000-0001-7633-9455, Penny, M., Favara, M., Sánchez, A. and Santhanakrishnan Vimaleswaran, K. ORCID: https://orcid.org/0000-0002-8485-8930 (2025) Interaction between genetic risk score and dietary carbohydrate intake on high-density lipoprotein cholesterol levels: findings from the study of obesity, nutrition, genes and social factors (SONGS). Clinical Nutrition ESPEN, 66. pp. 83-92. ISSN 2405-4577 doi: 10.1016/j.clnesp.2024.12.027

2024

Al Thunayan, T. (2024) Investigating the effects of Podoplanin signalling on VEGF-C-mediated signalling in human dermal lymphatic endothelial cells. PhD thesis, University of Reading. doi: 10.48683/1926.00117896

Alaajam, F. M. M. (2024) Junctional complexes and the control of platelet function. PhD thesis, University of Reading. doi: 10.48683/1926.00119679

Alboaklah, H. K. M. ORCID: https://orcid.org/0000-0003-0272-5040, McNeish, A. J. ORCID: https://orcid.org/0000-0002-3466-8442 and Leake, D. S. ORCID: https://orcid.org/0000-0002-1742-6134 (2024) Low density lipoprotein oxidized under lysosomal conditions decreases arterial vasodilatation. Free Radical Research. ISSN 1029-2470 doi: 10.1080/10715762.2024.2403038

Authi, K. S., Khan, S., Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 and Brain, S. D. (2024) Evidence that Inositol-1,4,5-trisphosphate-3-kinase and Inositol-1,3,4,5-tetrakisphosphate are negative regulators of platelet function. Research and Practice in Thrombosis and Haemostasis, 8 (1). 102326. ISSN 2475-0379 doi: 10.1016/j.rpth.2024.102326

Bournot, A. R., Darling, A. L., Givens, I. D. ORCID: https://orcid.org/0000-0002-6754-6935, Lovegrove, J. A. ORCID: https://orcid.org/0000-0001-7633-9455 and Lanham-New, S. (2024) Effect of vitamin D status and vitamin D supplementation on immune function and prevention of acute respiratory tract infections in dark-skinned individuals: a systematic review and meta-analysis. Public Health Nutrition, 27 (1). e224. ISSN 1368-9800 doi: 10.1017/S1368980024001861

Bozbas, E., Zhou, R., Soyama, S., Allen-Redpath, K., Mitchell, J. L., Fisk, H. L., Calder, P. C., Jones, C. ORCID: https://orcid.org/0000-0001-7537-1509, Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352, Fischer, R., Hester, S. and Yaqoob, P. ORCID: https://orcid.org/0000-0002-6716-7599 (2024) Dietary n-3 polyunsaturated fatty acids alter the number, fatty acid profile and coagulatory activity of circulating and platelet-derived extracellular vesicles: a randomized, controlled crossover trial. American Journal of Clinical Nutrition, 119 (5). pp. 1175-1186. ISSN 1938-3207 doi: 10.1016/j.ajcnut.2024.03.008

Edmunds, N. S., Genc, A. G. and McGuffin, L. J. ORCID: https://orcid.org/0000-0003-4501-4767 (2024) Benchmarking of AlphaFold2 accuracy self-estimates as indicators of empirical model quality and ranking: a comparison with independent model quality assessment programmes. Bioinformatics, 40 (8). btae491. ISSN 1460-2059 doi: 10.1093/bioinformatics/btae491

Eichelmann, F., Prada, M., Sellem, L., Jackson, K. G. ORCID: https://orcid.org/0000-0002-0070-3203, Salas Salvadó,, J., Razquin Burillo, C., Estruch, R., Friedén,, M., Rosqvist, F., Risérus, U., Rexrode, K. M., Guasch-Ferré, M., Sun, Q., Willett, W. C., Martinez-Gonzalez, M. A., Lovegrove, J. A. ORCID: https://orcid.org/0000-0001-7633-9455, Hu, F. B., Schulze, M. B. and Wittenbecher, C. (2024) Lipidome changes due to improved dietary fat quality inform cardiometabolic risk reduction and precision nutrition. Nature Medicine, 30 (10). pp. 2867-2877. ISSN 1078-8956 doi: 10.1038/s41591-024-03124-1

Franks, S. J., Dunster, J. L. ORCID: https://orcid.org/0000-0001-8986-4902, Carding, S. R., Lord, J. M., Hewison, M., Calder, P. C. and King, J. R. (2024) Modelling the influence of vitamin D and probiotic supplementation on the microbiome and immune response. Mathematical Medicine and Biology: A Journal of the IMA, 41 (4). pp. 304-345. ISSN 1477-8602 doi: 10.1093/imammb/dqae017

Genc, A. G. and McGuffin, L. J. ORCID: https://orcid.org/0000-0003-4501-4767 (2024) Beyond AlphaFold2: the impact of AI for the further improvement of protein structure prediction. In: Kloczkowski, A., Kurgan, L. and Faraggi, E. (eds.) Prediction of Protein Secondary Structure. Methods in molecular biology, 2867. Springer Protocols, New York, NY, pp. 121-139. ISBN 9781071641958 doi: 10.1007/978-1-0716-4196-5_7

Koutsos, A., Griffin, B. A., Antoni, R., Ozen, E. ORCID: https://orcid.org/0000-0001-6203-7018, Sellem, L., Wong, G., Ayyad, H., Fielding, B. A., Robertson, M. D., Swann, J., Jackson, K. G. ORCID: https://orcid.org/0000-0002-0070-3203 and Lovegrove, J. A. ORCID: https://orcid.org/0000-0001-7633-9455 (2024) Variation of LDL-cholesterol in response to the replacement of saturated with unsaturated fatty acids: a nonrandomised, sequential dietary intervention; the Reading, Imperial, Surrey, Saturated fat Cholesterol Intervention (“RISSCI”-1) study. American Journal of Clinical Nutrition, 120 (4). pp. 854-863. ISSN 1938-3207 doi: 10.1016/j.ajcnut.2024.07.032

Lovegrove, J. A. ORCID: https://orcid.org/0000-0001-7633-9455 (2024) Benefits and challenges associated with ‘raising our daily pulses’. Nutrition Bulletin, 49 (4). pp. 425-428. ISSN 1471-9827 doi: 10.1111/nbu.12714

Maharaj, A. V. ORCID: https://orcid.org/0000-0001-8051-3866, Ishida, M., Rybak, A., Elfeky, R., Andrews, A. ORCID: https://orcid.org/0000-0003-2390-657X, Joshi, A., Elmslie, F., Joensuu, A. ORCID: https://orcid.org/0000-0002-7547-7458, Kantojärvi, K., Jia, R. Y., Perry, J. R. B. ORCID: https://orcid.org/0000-0001-6483-3771, O’Toole, E. A. ORCID: https://orcid.org/0000-0002-4084-4836, McGuffin, L. J. ORCID: https://orcid.org/0000-0003-4501-4767, Hwa, V. ORCID: https://orcid.org/0000-0003-0517-9049 and Storr, H. L. ORCID: https://orcid.org/0000-0002-9963-1931 (2024) QSOX2 deficiency-induced short stature, gastrointestinal dysmotility and immune dysfunction. Nature Communications, 15 (1). 8420. ISSN 2041-1723 doi: 10.1038/s41467-024-52587-w

McGuffin, L. J. ORCID: https://orcid.org/0000-0003-4501-4767 and Alharbi, S. M. A. (2024) ModFOLD9: a web server for independent estimates of 3D protein model quality. Journal of Molecular Biology, 436 (17). 168531. ISSN 1089-8638 doi: 10.1016/j.jmb.2024.168531

Ozen, E. ORCID: https://orcid.org/0000-0001-6203-7018, Lovegrove, J. A. ORCID: https://orcid.org/0000-0001-7633-9455 and Jackson, K. G. ORCID: https://orcid.org/0000-0002-0070-3203 (2024) Association between body composition and cardiometabolic disease risk – role of dietary fat intake and APOLIPOPROTEIN E genotype on this relationship. Proceedings of the Nutrition Society. ISSN 0029-6651 doi: 10.1017/S0029665124000053

Protty, M. B., Tyrell, V. J., Allen-Redpath, K., Soyama, S., Hajeyah, A. A., Costa, D., Choudhury, A., Mitra, R., Sharman, A., Yaqoob, P. ORCID: https://orcid.org/0000-0002-6716-7599, Jenkins, P. V., Yousef, Z. ORCID: https://orcid.org/0000-0002-6716-7599, Collins, P. W. and O'Donnell, V. B. (2024) Thrombin generation is associated with extracellular vesicle and leukocyte lipid membranes in atherosclerotic cardiovascular disease. Arteriosclerosis Thrombosis and Vascular Biology, 44 (9). pp. 2038-2052. ISSN 1524-4636 doi: 10.1161/ATVBAHA.124.320902

Sonavane, M. (2024) Novel strategies to treat snake venom induced muscle damage. PhD thesis, University of Reading. doi: 10.48683/1926.00117785

Vogtschmidt, Y. D., Soedamah-Muthu, S. S., Imamura, F., Givens, D. I. ORCID: https://orcid.org/0000-0002-6754-6935 and Lovegrove, J. A. ORCID: https://orcid.org/0000-0001-7633-9455 (2024) Replacement of saturated fatty acids from meat by dairy sources in relation to incident cardiovascular disease: the European prospective investigation into cancer and nutrition (EPIC)-Norfolk study. American Journal of Clinical Nutrition, 119 (6). pp. 1495-1503. ISSN 1938-3207 doi: 10.1016/j.ajcnut.2024.04.007

2023

Adiyaman, R. and McGuffin, L. J. ORCID: https://orcid.org/0000-0003-4501-4767 (2023) Using local protein model quality estimates to guide a molecular dynamics-based refinement strategy. In: Filipek, S. (ed.) Homology Modeling: Methods and Protocols. Methods in Molecular Biology. Springer Nature, New York, pp. 119-140. ISBN 9781071629734 doi: 10.1007/978-1-0716-2974-1_7

Adiyaman, R., Edmunds, N. S., Genc, A. G., Alharbi, S. M. A. and McGuffin, L. ORCID: https://orcid.org/0000-0003-4501-4767 (2023) Improvement of protein tertiary and quaternary structure predictions using the ReFOLD refinement method and the AlphaFold2 recycling process. Bioinformatics Advances, 3 (1). vbad078. ISSN 2635-0041 doi: 10.1093/bioadv/vbad078

AlOuda, S. K., Sasikumar, P., AlThunayan, T., Alaajam, F., Khan, S., Sahli, K. A., Abohassan, M. S., Pollitt, A. ORCID: https://orcid.org/0000-0001-8706-5154, Jung, S. M. and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 (2023) Role of heat shock protein 47 in platelet glycoprotein VI dimerisation and signaling. Research and Practice in Thrombosis and Haemostasis, 7 (6). 102177. ISSN 2475-0379 doi: 10.1016/j.rpth.2023.102177

Aldaghmi, A. S. M. (2023) Understanding the mechanisms of the regulation of platelet function by thiol isomerase enzymes. PhD thesis, University of Reading. doi: 10.48683/1926.00119425

Alharbi, S. M. A. and McGuffin, L. J. ORCID: https://orcid.org/0000-0003-4501-4767 (2023) Machine learning methods for predicting protein contacts. In: Kurgan, L. (ed.) Machine Learning in Bioinformatics of Protein Sequences: Algorithms, Databases and Resources for Modern Protein Bioinformatics. World Scientific, pp. 155-181. ISBN 9789811258572 doi: 10.1142/9789811258589_0006

Bye, A. P. ORCID: https://orcid.org/0000-0002-2061-2253, Kriek, N., Sage, T., Rawlings, S. J., Prodger, C., Kesavan, M., Lees, C., Booth, S., Cowen, L. G., Shefferd, K., Desborough, M. J., Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 and Eyre, T. A. (2023) Pirtobrutinib results in reversible platelet dysfunction compared to ibrutinib and acalabrutinib. Haematologica, 108 (5). ISSN 1592-8721 doi: 10.3324/haematol.2022.281402

Cheung, H. Y. F., Zou, J., Tantiwong, C., Fernandez, D. I., Huang, J., Ahrends, R., Roest, M., Cavill, R., Gibbins, J. ORCID: https://orcid.org/0000-0002-0372-5352 and Heemskerk, J. W. M. (2023) High-throughput assessment identifying major platelet Ca2+ entry pathways via tyrosine kinase-linked and G protein-coupled receptors. Cell Calcium, 112. 102738. ISSN 0143-4160 doi: 10.1016/j.ceca.2023.102738

De Simone, I. (2023) Novel mechanisms of platelet activation and sustained signalling through GPVI and PAR1. PhD thesis, University of Reading. doi: 10.48683/1926.00112631

Dodd, J., Sweby, P. K. ORCID: https://orcid.org/0009-0003-8488-0251, Mayes, S., Murchie, E. H., Karunaratne, A. S., Massawe, F. and Tindall, M. J. (2023) A multiscale mathematical model describing the growth and development of bambara groundnut. Journal of Theoretical Biology, 560. 111373. ISSN 0022-5193 doi: 10.1016/j.jtbi.2022.111373

Edmunds, N. S., Alharbi, S. M.A., Genc, A. G., Adiyaman, R. and McGuffin, L. J. ORCID: https://orcid.org/0000-0003-4501-4767 (2023) Estimation of model accuracy in CASP15 using the ModFOLDdock server. Proteins: Structure, Function, and Bioinformatics, 91 (12). pp. 1871-1878. ISSN 1097-0134 doi: 10.1002/prot.26532

Gelzinis, J. A., Szahaj, M. K., Bekendam, R. H., Wurl, S. E., Pantos, M. M., Verbetsky, C. A., Dufresne, A., Shea, M., Howard, K. C., Tsodikov, O. V., Garneau‐Tsodikova, S., Zwicker, J. I. and Kennedy, D. R. ORCID: https://orcid.org/0000-0002-4359-6911 (2023) Targeting thiol isomerase activity with zafirlukast to treat ovarian cancer from the bench to clinic. The FASEB Journal, 37 (5). e22914. ISSN 1530-6860 doi: 10.1096/fj.202201952r

Gerencer, M. and McGuffin, L. J. ORCID: https://orcid.org/0000-0003-4501-4767 (2023) Are the integrin binding motifs within SARS CoV-2 spike protein and MHC class II alleles playing the key role in COVID-19? Frontiers in Immunology, 14. ISSN 1664-3224 doi: 10.3389/fimmu.2023.1177691

Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 (2023) Adding fuel to the flames in pre-eclampsia: the platelet connection. Journal of Thrombosis and Haemostasis, 21 (7). pp. 1750-1752. ISSN 1538-7933 doi: 10.1016/j.jtha.2023.03.031

Kuravi, S. J., Ahmed, N. S., Taylor, K. A. ORCID: https://orcid.org/0000-0002-4599-7727, Capes, E. M., Bye, A. ORCID: https://orcid.org/0000-0002-2061-2253, Unsworth, A. J., Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 and Pugh, N. (2023) Delineating zinc influx mechanisms during platelet activation. International Journal of Molecular Sciences, 24 (14). 11689. ISSN 1422-0067 doi: 10.3390/ijms241411689

Lovegrove, J. A. ORCID: https://orcid.org/0000-0001-7633-9455, O'Sullivan, D. M. ORCID: https://orcid.org/0000-0003-4889-056X, Tosi, P. ORCID: https://orcid.org/0000-0003-4171-6120, Millan, E. ORCID: https://orcid.org/0000-0002-2421-2855, Todman, L. C. ORCID: https://orcid.org/0000-0003-1232-294X, Bishop, J. ORCID: https://orcid.org/0000-0003-2114-230X, Chatzifragkou, A. ORCID: https://orcid.org/0000-0002-9255-7871, Clegg, M. E., Hammond, J. ORCID: https://orcid.org/0000-0002-6241-3551, Jackson, K. G. ORCID: https://orcid.org/0000-0002-0070-3203, Jones, P. J. ORCID: https://orcid.org/0000-0003-3464-5424, Lignou, S. ORCID: https://orcid.org/0000-0001-6971-2258, Macready, A. L. ORCID: https://orcid.org/0000-0003-0368-9336, McMeel, Y., Parker, J. ORCID: https://orcid.org/0000-0003-4121-5481, Rodriguez-Garcia, J. ORCID: https://orcid.org/0000-0002-4986-3144, Sharp, P., Shaw, L. J., Smith, L. G. ORCID: https://orcid.org/0000-0002-9898-9288 and Tebbit, M. (2023) 'Raising the pulse': the environmental, nutritional and health benefits of pulse-enhanced foods. Nutrition Bulletin, 48 (1). pp. 134-143. ISSN 1471-9827 doi: 10.1111/nbu.12601

Maghrabi, A. H. A., Aldowsari, F. M. F. and McGuffin, L. J. ORCID: https://orcid.org/0000-0003-4501-4767 (2023) Quality estimates for 3D protein models. In: Filipek, S. (ed.) Homology Modeling: Methods and Protocols. Methods in Molecular Biology, 2627. Springer Nature, New York, pp. 101-118. ISBN 9781071629734 doi: 10.1007/978-1-0716-2974-1_6

Markey, O., Garcimartín, A., Vasilopoulou, D., Kliem, K. E. ORCID: https://orcid.org/0000-0002-0058-8225, Fagan, C. C. ORCID: https://orcid.org/0000-0002-2101-8694, Humphries, D. J., Todd, S. ORCID: https://orcid.org/0000-0002-9981-923X, Givens, D. I. ORCID: https://orcid.org/0000-0002-6754-6935, Lovegrove, J. A. ORCID: https://orcid.org/0000-0001-7633-9455 and Jackson, K. G. ORCID: https://orcid.org/0000-0002-0070-3203 (2023) Impact of dairy fat manipulation on endothelial function and lipid regulation in human aortic endothelial cells exposed to human plasma samples: an in vitro investigation from the RESET study. European Journal of Nutrition. ISSN 1436-6215 doi: 10.1007/s00394-023-03284-9

McGuffin, L. J. ORCID: https://orcid.org/0000-0003-4501-4767, Edmunds, N. S., Genc, A. G., Alharbi, S. M. A., Salehe, B. R. and Adiyaman, R. (2023) Prediction of protein structures, functions and interactions using the IntFOLD7, MultiFOLD and ModFOLDdock servers. Nucleic Acids Research, 51 (W1). W274-W280. ISSN 1362-4962 doi: 10.1093/nar/gkad297

Mitchell, J. L., Khan, D., Rana, R. H., Kriek, N., Unsworth, A. J., Sage, T., Bye, A. P. ORCID: https://orcid.org/0000-0002-2061-2253, Laffan, M., Shapiro, S., Thakurta, A., Grech, H., Ramasamy, K. and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 (2023) Multiple myeloma and its treatment contribute to increased platelet reactivity. Platelets, 34 (1). 2264940. ISSN 1369-1635 doi: 10.1080/09537104.2023.2264940

Nelson, M. R., Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 and Dunster, J. L. ORCID: https://orcid.org/0000-0001-8986-4902 (2023) Platelet-driven routes to chaos in a model of hepatitis. Chaos, Solitons & Fractals, 170. 113338. ISSN 1873-2887 doi: 10.1016/j.chaos.2023.113338

Provenzale, I. (2023) The modulatory roles of collagen and endothelial cells on platelet function. PhD thesis, University of Reading. doi: 10.48683/1926.00118921

Pushpass, R.-A. G., Alzoufairi, S., Mancini, A., Quilter, K., Fava, F., Delaiti, S., Vrhovsek, U., Christensen, C., Joyce, S. A., Tuohy, K. M., Jackson, K. G. ORCID: https://orcid.org/0000-0002-0070-3203 and Lovegrove, J. A. ORCID: https://orcid.org/0000-0001-7633-9455 (2023) Chronic consumption of probiotics, oats and apples have differential effects on postprandial bile acid profile and cardiometabolic disease risk markers compared to an isocaloric control (cornflakes): a randomized trial. The American Journal of Clinical Nutrition, 117 (2). ISSN 0002-9165 doi: 10.1016/j.ajcnut.2022.10.013

Ranjbar, J., Njoroge, W. ORCID: https://orcid.org/0009-0003-1365-5129, Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352, Roach, P. ORCID: https://orcid.org/0000-0003-4135-9733, Yang, Y. ORCID: https://orcid.org/0000-0002-1362-6040 and Harper, A. G. S. ORCID: https://orcid.org/0000-0003-2413-4823 (2023) Developing biomimetic hydrogels of the arterial wall as a prothrombotic substrate for in vitro human thrombosis models. Gels, 9 (6). 477. ISSN 2310-2861 doi: 10.3390/gels9060477

Sellem, L., Eichelmann, F., Jackson, K. G. ORCID: https://orcid.org/0000-0002-0070-3203, Wittenbecher, C., Schultze, M. and Lovegrove, J. A. ORCID: https://orcid.org/0000-0001-7633-9455 (2023) Replacement of dietary saturated with unsaturated fatty acids is associated with beneficial effects on lipidome metabolites: a secondary analysis of a randomized trial. American Journal of Clinical Nutrition, 117 (6). pp. 1248-1261. ISSN 0002-9165 doi: 10.1016/j.ajcnut.2023.03.024

Stowell, J. D., Mela, D. J., Coppens, P., Lovegrove, J. A. ORCID: https://orcid.org/0000-0001-7633-9455, McArdle, H. J., van der Sman, F. J. P., Verhagen, H., Young, H. A. and Young, I. S. (2023) Dietary supplements, 'functional' and 'super' foods: Science, regulations and roles in the diet”. Royal Society of Medicine, London, 29 November 2022. In: Meeting on “Dietary supplements, 'functional' and 'super' foods: Science, regulations and roles in the diet”, 29 November 2022, Royal Society of Medicine, London. doi: 10.31219/osf.io/9z3x2

Tantiwong, C., Dunster, J. L. ORCID: https://orcid.org/0000-0001-8986-4902, Cavill, R., Tomlinson, M. G., Wierling, C., Heemskerk, J. W. M. and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 (2023) An agent-based approach for modelling and simulation of glycoprotein VI receptor diffusion, localisation and dimerisation in platelet lipid rafts. Scientific Reports, 13. 3906. ISSN 2045-2322 doi: 10.1038/s41598-023-30884-6

Thienel, M., Müller-Reif, J. B., Zhang, Z., Ehreiser, V., Huth, J., Shchurovska, K., Kilani, B., Schweizer, L., Geyer, P. E., Zweibel, M., Novotny, J., Lüsebrink, E., Little, G., Orban, M., Nicolai, L., El Nemr, S., Titova, A., Spannagl, M., Kindberg, J., Evans, A. L., Mach, O., Vogel, M., Tiedt, S., Ormanns, S., Kessler, B., Dueck, A., Friebe, A., Godsk Jørgensen, P., Majzoub-Altweck, M., Blutke, A., Polzin, A., Stark, K., Kääb, S., Maier, D., Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352, Limper, U., Frobert, O., Mann, M., Massberg, S. and Petzold, T. (2023) Immobility-associated thromboprotection is conserved across mammalian species from bear to human. Science, 380 (6641). pp. 178-187. ISSN 1095-9203 doi: 10.1126/science.abo5044

Tindall, M. J. ORCID: https://orcid.org/0000-0001-6069-5260, Cucurull-Sanchez, L., Mistry, H. and Yates, J. W.T. (2023) Quantitative systems pharmacology and machine learning: a match made in heaven or hell? The Journal of Pharmacology and Experimental Therapeutics, 387 (1). pp. 92-99. ISSN 1521-0103 doi: 10.1124/jpet.122.001551

Verdier, H., Thomas, P., Batista, J. ORCID: https://orcid.org/0000-0001-5406-6353, Kempster, C. ORCID: https://orcid.org/0000-0001-5721-1050, McKinney, H., Gleadall, N. ORCID: https://orcid.org/0000-0002-1132-1059, Danesh, J., Mumford, A. ORCID: https://orcid.org/0000-0002-5523-511X, Heemskerk, J. W. M. ORCID: https://orcid.org/0000-0002-2848-5121, Ouwehand, W. H. ORCID: https://orcid.org/0000-0002-7744-1790, Downes, K., Astle, W. J. ORCID: https://orcid.org/0000-0001-8866-6672 and Turro, E. ORCID: https://orcid.org/0000-0002-1820-6563 (2023) A signature of platelet reactivity in CBC scattergrams reveals genetic predictors of thrombotic disease risk. Blood, 142 (22). pp. 1895-1908. ISSN 1528-0020 doi: 10.1182/blood.2023021100

2022

Albadawi, D. A. I. (2022) Impact of edible plant extracts and isolated compounds on the modulation of platelet function. PhD thesis, University of Reading. doi: 10.48683/1926.00117339

Dorrington, N., Fallaize, R., Hobbs, D., Weech, M. ORCID: https://orcid.org/0000-0003-1738-877X and Lovegrove, J. A. ORCID: https://orcid.org/0000-0001-7633-9455 (2022) Diet Quality Index for older adults (DQI-65): development and use in predicting adherence to dietary recommendations and health markers in the UK National Diet and Nutrition Survey. British Journal of Nutrition, 128 (11). pp. 2139-2207. ISSN 0007-1145 doi: 10.1017/S0007114521005043

Downes, K., Zhao, X., Gleadall, N. S., Antanavicius, N., McKinney, H., Kempster, C., Batista, J., Thomas, P. L., Cooper, M., Michael, J. V., Kreuzhuber, R., Wedderburn, K., Waller, K., Varney, B., Kriek, N., Ashford, S. E., Stirrups, K. E., Dunster, J. L. ORCID: https://orcid.org/0000-0001-8986-4902, McKenzie, S. E., Ouwehand, W. H., Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352, Yang, J., Astle, W. J. and Ma, P. (2022) G protein-coupled receptor kinase 5 regulates thrombin signaling in platelets via PAR-1. Blood Advances, 6 (7). pp. 2319-2330. ISSN 2473-9529 doi: 10.1182/bloodadvances.2021005453

Eichelmann, F., Sellem, L., Wittenbecher, C., Jäger, S., Kuxhaus, O., Prada, M., Cuadrat, R., Jackson, K. G. ORCID: https://orcid.org/0000-0002-0070-3203, Lovegrove, J. A. ORCID: https://orcid.org/0000-0001-7633-9455 and Schulze, M. B. (2022) Deep lipidomics in human plasma – cardiometabolic disease risk and effect of dietary fat modulation. Circulation, 146 (1). pp. 21-35. ISSN 1524-4539 doi: 10.1161/CIRCULATIONAHA.121.056805

Fan, L. M., Liu, F., Du, J., Geng, L. and Li, J.-M. ORCID: https://orcid.org/0000-0002-3294-3818 (2022) Inhibition of endothelial Nox2 activation by LMH001 protects mice from angiotensin II-induced vascular oxidative stress, hypertension and aortic aneurysm. Redox Biology, 51. 102269. ISSN 22132317 doi: 10.1016/j.redox.2022.102269

Jackson, K. G. ORCID: https://orcid.org/0000-0002-0070-3203, Newens, K. J., Fry, M. J., Thompson, A. K. and Williams, C. M. (2022) Differential effects of single fatty acids and fatty acid mixtures on the phosphoinositide 3-kinase/Akt/eNOS pathway in endothelial cells. European Journal of Nutrition, 61. pp. 2463-2473. ISSN 1436-6215 doi: 10.1007/s00394-022-02821-2

Livingstone, K. M., Brayner, B., Celis-Morales, C., Moschonis, G., Manios, Y., Traczyk, I., Drevon, C. A., Daniel, H., Saris, W. H. M., Lovegrove, J. A. ORCID: https://orcid.org/0000-0001-7633-9455, Gibney, M., Gibney, E. R., Brennan, L., Martinez, J. A. and Mathers, J. C. (2022) Associations between dietary patterns, FTO genotype and obesity in adults from seven European countries. European Journal of Nutrition, 61. pp. 2953-2965. ISSN 1436-6215 doi: 10.1007/s00394-022-02858-3

Markey, O., Vasilopoulou, D., Kliem, K. E. ORCID: https://orcid.org/0000-0002-0058-8225, Fagan, C. C. ORCID: https://orcid.org/0000-0002-2101-8694, Grandison, A. S., Sutton, R., Humphries, D. J., Todd, S. ORCID: https://orcid.org/0000-0002-9981-923X, Jackson, K. G. ORCID: https://orcid.org/0000-0002-0070-3203, Givens, D. I. ORCID: https://orcid.org/0000-0002-6754-6935 and Lovegrove, J. A. ORCID: https://orcid.org/0000-0001-7633-9455 (2022) Effect of fat reformulated dairy food consumption on postprandial flow-mediated dilatation and cardiometabolic risk biomarkers compared with conventional dairy: a randomized, controlled trial. American Journal of Clinical Nutrition, 115 (3). pp. 679-693. ISSN 0002-9165 doi: 10.1093/ajcn/nqab428

Mazidi, M., Webb, R. J., George, E. S., Shekoohi, N., Lovegrove, J. A. ORCID: https://orcid.org/0000-0001-7633-9455 and Davies, I. G. (2022) Nutrient patterns are associated with discordant apoB and LDL: a population-based analysis. British Journal of Nutrition, 128 (4). pp. 712-720. ISSN 0007-1145 doi: 10.1017/S000711452100369X

McGuffin, L. J. ORCID: https://orcid.org/0000-0003-4501-4767, Aldowsari, F. M. F., Alharbi, S. M. A. and Adiyaman, R. (2022) ModFOLD8: accurate global and local quality estimates for 3D protein models. Nucleic Acids Research, 49 (W1). W425-W430. ISSN 1362-4962 doi: 10.1093/nar/gkab321

Ojo, O. O. and Leake, D. ORCID: https://orcid.org/0000-0002-1742-6134 (2022) Effects of lysosomal low density lipoprotein oxidation by ferritin on macrophage function. Free Radical Research. GFRR-OM-2022-0211. ISSN 1071-5762 doi: 10.1080/10715762.2022.2133703

Ozen, E. ORCID: https://orcid.org/0000-0001-6203-7018, Mihaylova, R., Weech, M. ORCID: https://orcid.org/0000-0003-1738-877X, Kinsella, S., Lovegrove, J. A. ORCID: https://orcid.org/0000-0001-7633-9455 and Jackson, K. G. ORCID: https://orcid.org/0000-0002-0070-3203 (2022) Association between dietary saturated fat with cardiovascular disease risk markers and body composition in healthy adults- findings from the cross-sectional BODYCON study. Nutrition & Metabolism, 19 (15). ISSN 1743-7075 doi: 10.1186/s12986-022-00650-y

Ozen, E. ORCID: https://orcid.org/0000-0001-6203-7018, Mihaylova, R. G., Lord, N. J., Lovegrove, J. A. ORCID: https://orcid.org/0000-0001-7633-9455 and Jackson, K. G. ORCID: https://orcid.org/0000-0002-0070-3203 (2022) Association between APOE Genotype with Body Composition and Cardiovascular Disease Risk Markers Is Modulated by BMI in Healthy Adults: findings from the BODYCON Study. International Journal of Molecular Sciences, 23 (17). 9766. ISSN 1422-0067 doi: 10.3390/ijms23179766

Poston, R. N., Chughtai, J., Ujkaj, D., Louis, H., Leake, D. S. ORCID: https://orcid.org/0000-0002-1742-6134 and Cooper, D. (2022) Monocytic cell adhesion to oxidised ligands: relevance to cardiovascular disease. Biomedicines, 10 (12). 3083. ISSN 2227-9059 doi: 10.3390/biomedicines10123083

Pycraft Hughes, M., Kruchek, E. J., Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352, Griffiths, O. V., Abdal, B. and Labeed, F. H. (2022) The platelet electrome: evidence for a role in regulation of function and surface interaction. Bioelectricity, 4 (3). pp. 153-159. ISSN 2576-3113 doi: 10.1089/bioe.2021.0044

Rajasekaran, M. B., Hussain, R., Siligardi, G., Andrews, S. C. ORCID: https://orcid.org/0000-0003-4295-2686 and Watson, K. A. ORCID: https://orcid.org/0000-0002-9987-8539 (2022) Crystal structure and metal binding properties of the periplasmic iron component EfeM from Pseudomonas syringae EfeUOB/M iron-transport system. BioMetals. ISSN 0966-0844 doi: 10.1007/s10534-022-00389-2

Sellem, L., Antoni, R., Koutsos, A., Ozen, E. ORCID: https://orcid.org/0000-0001-6203-7018, Wong, G., Ayyad, H., Weech, M. ORCID: https://orcid.org/0000-0003-1738-877X, Schulze, M. B., Wernitz, A., Fielding, B. A., Robertson, D., Jackson, K. G. ORCID: https://orcid.org/0000-0002-0070-3203, Griffin, B. A. and Lovegrove, J. A. ORCID: https://orcid.org/0000-0001-7633-9455 (2022) Impact of a food-based dietary fat exchange model for replacing dietary saturated with unsaturated fatty acids in healthy men on plasma phospholipids fatty acid profiles and dietary patterns. European Journal of Nutrition, 61. pp. 3669-3684. ISSN 1436-6215 doi: 10.1007/s00394-022-02910-2

Sellem, L., Srour, B., Jackson, K. G. ORCID: https://orcid.org/0000-0002-0070-3203, Hercberg, S., Galan, P., Kesse-Guyot, E., Julia, C., Fezeu, L., Deschasaux-Tanguy, M., Lovegrove, J. ORCID: https://orcid.org/0000-0001-7633-9455 and Touvier, M. (2022) Consumption of dairy products and cardiovascular disease risk: results from the French prospective cohort NutriNet-Santé. British Journal of Nutrition, 127 (5). pp. 752-762. ISSN 0007-1145 doi: 10.1017/S0007114521001422

Steenson, S., Shojaee-Moradie, F., Lovegrove, J. A. ORCID: https://orcid.org/0000-0001-7633-9455, Umpleby, A. M., Jackson, K. G. ORCID: https://orcid.org/0000-0002-0070-3203 and Fielding, B. A. (2022) Dose dependent effects of fructose and glucose on de novo palmitate and glycerol synthesis in an enterocyte cell model. Molecular Nutrition and Food Research, 66 (1). ISSN 1613-4133 doi: 10.1002/mnfr.202100456

Wright, J. R., Jones, S., Parvathy, S., Kaczmarek, L. K., Forsythe, I., Farndale, R. W., Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 and Mahaut-Smith, M. P. (2022) The voltage-gated K+ channel Kv1.3 modulates platelet motility and α2β1 integrin-dependent adhesion to collagen. Platelets, 33 (3). pp. 451-461. ISSN 0953-7104 doi: 10.1080/09537104.2021.1942818

Zenun Franco, R., Fallaize, R., Weech, M. ORCID: https://orcid.org/0000-0003-1738-877X, Hwang, F. ORCID: https://orcid.org/0000-0002-3243-3869 and Lovegrove, J. A. ORCID: https://orcid.org/0000-0001-7633-9455 (2022) Effectiveness of web-based personalized nutrition advice for adults using the eNutri web app: evidence from the EatWellUK randomized controlled trial. Journal of Medical Internet Research, 24 (4). ISSN 1438-8871 doi: 10.2196/29088

2021

Adiyaman, R. and McGuffin, L. ORCID: https://orcid.org/0000-0003-4501-4767 (2021) ReFOLD3: refinement of 3D protein models with gradual restraints based on predicted local quality and residue contacts. Nucleic Acids Research, 49 (W1). W589-W596. ISSN 1362-4962 doi: 10.1093/nar/gkab300

Ahmad, F., Mitchell, R., Houben, T., Palo, A., Yasdati, T., Parnell, A., Patel, K., Shiri-Sverdlov, R. and Leake, D. ORCID: https://orcid.org/0000-0002-1742-6134 (2021) Cysteamine decreases low density lipoprotein oxidation, causes regression of atherosclerosis and improves liver and muscle function in LDL receptor deficient mice. JAHA: Journal of the American Heart Association, 10 (18). ISSN 2047-9980 doi: 10.1161/JAHA.120.017524

Brackenridge, D. A. and McGuffin, L. J. ORCID: https://orcid.org/0000-0003-4501-4767 (2021) Proteins and their interacting partners: an introduction to protein–ligand binding site prediction methods with a focus on FunFOLD3. In: Cacace, A. M., Hickey, C. M. and Bekes, M. (eds.) Targeted Protein Degradation: Methods and Protocols. Methods in Molecular Biology, 2365. Springer, pp. 43-58. ISBN 9781071616642 doi: 10.1007/978-1-0716-1665-9

Bye, A. P. ORCID: https://orcid.org/0000-0002-2061-2253, Hoepel, W., Mitchell, J. L., Jegouic, S. M., Loureiro, S. ORCID: https://orcid.org/0009-0000-8886-6893, Sage, T., Vidarsson, G., Nouta, J., Wuhrer, M., de Taeye, S. W., van Gils, M., Kriek, N., Cooper, N., Jones, I. ORCID: https://orcid.org/0000-0002-7738-2516, den Dunnen, J. and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 (2021) Aberrant glycosylation of anti-SARS-CoV-2 spike IgG is a pro-thrombotic stimulus for platelets. Blood, 138 (16). pp. 1481-1489. ISSN 0006-4971 doi: 10.1182/blood.2021011871

Cai, H., Sasikumar, P., Little, G., Bihan, D., Hamaia, S. W., Zhou, A., Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 and Farndale, R. W. (2021) Identification of HSP47 binding site on native collagen and its implications on the development of HSP47 inhibitors. Biomolecules, 11 (7). 983. ISSN 2218-273X doi: 10.3390/biom11070983

Chamata, Y., Jackson, K. G. ORCID: https://orcid.org/0000-0002-0070-3203, Watson, K. A. ORCID: https://orcid.org/0000-0002-9987-8539 and Jauregi, P. (2021) Whey-derived peptides at the heart of the COVID-19 pandemic. International Journal of Molecular Sciences, 22 (21). 11662. ISSN 1422-0067 doi: 10.3390/ijms222111662

Derrick, D. J. A., Wolton, K., Currie, R. A. and Tindall, M. J. (2021) A mathematical model of the role of aggregation in sonic hedgehog signalling. PLoS computational biology, 17 (2). e1008562. ISSN 1553-7358 doi: 10.1371/journal.pcbi.1008562

Dunster, J. ORCID: https://orcid.org/0000-0001-8986-4902, Bye, A. ORCID: https://orcid.org/0000-0002-2061-2253, Kriek, N., Sage, T., Mitchell, J., Kempster, C., Batista, J., KcKinney, H., Thomas, P., Jones, C. ORCID: https://orcid.org/0000-0001-7537-1509, Downes, K., Unsworth, A. and Gibbins, J. ORCID: https://orcid.org/0000-0002-0372-5352 (2021) Multi-parameter phenotyping of platelet reactivity for stratification of human cohorts. Blood Advances, 5 (20). pp. 4017-4030. ISSN 2473-9529 doi: 10.1182/bloodadvances.2020003261

Edmunds, N. S. and McGuffin, L. J. ORCID: https://orcid.org/0000-0003-4501-4767 (2021) Computational methods for the elucidation of protein structure and interactions. In: Owens, R. J. (ed.) Methods Molecular Biology: Structural Proteomics. Methods Molecular Biology, 2305. Springer Nature, pp. 23-52. ISBN 9781071614068 doi: 10.1007/978-1-0716-1406-8_2

Fernández, D. I. ORCID: https://orcid.org/0000-0002-5055-9019, Provenzale, I., Cheung, H. Y. F., van Groningen, J., Tullemans, B. M. E., Veninga, A., Dunster, J. L. ORCID: https://orcid.org/0000-0001-8986-4902, Honarnejad, S. ORCID: https://orcid.org/0000-0002-4558-501X, van den Hurk, H., Kuijpers, M. J. E. and Heemskerk, J. W. M. (2021) Ultra-high throughput Ca2+ assay in platelets to distinguish ITAM-linked and G-protein coupled receptor activation. iScience, 25 (1). 103718. ISSN 2589-0042 doi: 10.1016/j.isci.2021.103718

Fuller, S. J., Edmunds, N. S., McGuffin, L. J. ORCID: https://orcid.org/0000-0003-4501-4767, Hardyman, M. A., Cull, J. J., Alharbi, H. O., Meijles, D. N., Sugden, P. H. and Clerk, A. ORCID: https://orcid.org/0000-0002-5658-0708 (2021) MAP4K4 expression in cardiomyocytes: multiple isoforms, multiple phosphorylations and interactions with striatins. Biochemical Journal, 478 (11). pp. 2121-2143. ISSN 0264-6021 doi: 10.1042/BCJ20210003

Gaspar, R. S., Ferreira, P., Mitchell, J. L., Pula, G. and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 (2021) Platelet-derived extracellular vesicles express NADPH oxidase-1 (Nox-1), generate superoxide and modulate platelet function. Free Radical Biology and Medicine, 165. pp. 395-400. ISSN 0891-5849 doi: 10.1016/j.freeradbiomed.2021.01.051

Gaspar, R. S., Mansilla, S., Vieira, V. A., da Silva, L. B., Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352, Castro, L., Trostchansky, A. and de A. Paes, A. M. (2021) The protein disulphide isomerase inhibitor CxxCpep modulates oxidative burst and mitochondrial function in platelets. Free Radical Biology and Medicine, 172. pp. 668-674. ISSN 0891-5849 doi: 10.1016/j.freeradbiomed.2021.07.011

Griffin, B. A. and Lovegrove, J. A. ORCID: https://orcid.org/0000-0001-7633-9455 (2021) Evidence for beneficial associations between isoenergetic macronutrient exchanges and serum non-HDL cholesterol, a measure of all circulating atherogenic, apoB-containing lipoproteins. Journal of Nutrition, 151 (8). pp. 2096-2098. ISSN 1541-6100 doi: 10.1093/jn/nxab127

Griffin, B. A., Mensink, R. P. and Lovegrove, J. A. ORCID: https://orcid.org/0000-0001-7633-9455 (2021) Does variation in serum LDL-cholesterol response to dietary fatty acids help explain the controversy over fat quality and cardiovascular disease risk? Atherosclerosis, 328. pp. 108-113. ISSN 0021-9150 doi: 10.1016/j.atherosclerosis.2021.03.024

Holbrook, L.-M., Keeton, S. J., Sasikumar, P., Nock, S., Gelzinis, J., Brunt, E., Ryan, S., Pantos, M. M., Verbetsky, C. A., Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 and Kennedy, D. R. (2021) Zafirlukast is a broad-spectrum thiol isomerase inhibitor that inhibits thrombosis without altering bleeding times. British Journal of Pharmacology, 178 (3). pp. 550-563. ISSN 1476-5381 doi: 10.1111/bph.15291

Houben, T., Yadati, T., De Kruijf, R., Gijbels, M. J., Luiken, J., Van Zandvoort, M., Kapsokalyvas, D., Lütjohann, D., Westerterp, M., Plat, J., Leake, D. ORCID: https://orcid.org/0000-0002-1742-6134 and Shiri-Sverdlov, R. (2021) Pro-inflammatory implications of 2-hydroxypropyl-β-cyclodextrin treatment. Frontiers in Immunology, 12. 716357. ISSN 1664-3224 doi: 10.3389/fimmu.2021.716357

Jannah, N., Hadjiloucas, S. ORCID: https://orcid.org/0000-0003-2380-6114 and Al-Malki, J. (2021) Arrhythmia detection using multi-lead ECG spectra and Complex Support Vector Machine classifiers. Procedia Computer Science, 194. pp. 69-79. ISSN 1877-0509 doi: 10.1016/j.procs.2021.10.060

Kryshtafovych, A. ORCID: https://orcid.org/0000-0001-5066-7178, Moult, J. ORCID: https://orcid.org/0000-0002-3012-2282, Billings, W. M., Della Corte, D. ORCID: https://orcid.org/0000-0002-8884-9724, Fidelis, K. ORCID: https://orcid.org/0000-0002-8061-412X, Kwon, S., Olechnovič, K. ORCID: https://orcid.org/0000-0003-4918-9505, Seok, C. ORCID: https://orcid.org/0000-0002-1419-9888, Venclovas, Č., Won, J., Adiyaman, R. and McGuffin, L. ORCID: https://orcid.org/0000-0003-4501-4767 (2021) Modeling SARS‐CoV2 proteins in the CASP ‐commons experiment. Proteins: Structure, Function, and Bioinformatics, 89 (12). pp. 1987-1996. ISSN 0887-3585 doi: 10.1002/prot.26231

Livingstone, K. M., Celis-Morales, C., Navas-Carretero, S., San-Cristobal, R., Forster, H., Woolhead, C., O’Donovan, C. B., Moschonis, G., Manios, Y., Traczyk, I., Gundersen, T. E., Drevon, C. A., Marsaux, C. F. M., Fallaize, R., Macready, A. L. ORCID: https://orcid.org/0000-0003-0368-9336, Daniel, H., Saris, W. H. M., Lovegrove, J. A. ORCID: https://orcid.org/0000-0001-7633-9455, Gibney, M., Gibney, E. R., Walsh, M., Brennan, L., Martinez, J. A. and Mathers, J. C. (2021) Personalised nutrition advice reduces intake of discretionary foods and beverages: findings from the Food4Me randomised controlled trial. International Journal of Behavioral Nutrition and Physical Activity, 18 (1). 70. ISSN 1479-5868 doi: 10.1186/s12966-021-01136-5

Markey, O., Vasilopoulou, D., Kliem, K. E. ORCID: https://orcid.org/0000-0002-0058-8225, Fagan, C. C. ORCID: https://orcid.org/0000-0002-2101-8694, Grandison, A. S., Sutton, R., Humphries, D. J., Todd, S. ORCID: https://orcid.org/0000-0002-9981-923X, Jackson, K. G. ORCID: https://orcid.org/0000-0002-0070-3203, Givens, D. I. ORCID: https://orcid.org/0000-0002-6754-6935 and Lovegrove, J. A. ORCID: https://orcid.org/0000-0001-7633-9455 (2021) Postprandial fatty acid profile, but not cardiometabolic risk markers, is modulated by dairy fat manipulation in adults with moderate cardiovascular disease risk: the randomized controlled REplacement of SaturatEd fat in dairy on Total cholesterol (RESET) study. Journal of Nutrition, 151 (7). pp. 1755-1768. ISSN 1541-6100 doi: 10.1093/jn/nxab050

Navas-Carretero, S., San-Cristobal, R., Alvarez-Alvarez, I., Celis-Morales, C., Livingstone, K. M., O'Donovan, C. B., Mavrogianni, C., Lambrinou, C. P., Manios, Y., Traczyck, I., Drevon, C. A., Marsaux, C. F. M., Saris, W. H. M., Fallaize, R., Macready, A. L. ORCID: https://orcid.org/0000-0003-0368-9336, Lovegrove, J. A. ORCID: https://orcid.org/0000-0001-7633-9455, Gundersen, T. E., Walsh, M., Brennan, L., Gibney, E. R., Gibney, M., Mathers, J. C. and Martinez, J. A. (2021) Interactions of carbohydrate intake and physical activity with regulatory genes affecting glycaemia: a Food4Me study analysis. Lifestyle Genomics, 14 (3). pp. 63-72. ISSN 2504-3188 doi: 10.1159/000515068

Nock, S. (2021) The dual kinase and scaffold function of Btk downstream of GPVI and CLEC-2 in platelets. PhD thesis, University of Reading. doi: 10.48683/1926.00101688

Ojo, O. O. and Leake, D. S. ORCID: https://orcid.org/0000-0002-1742-6134 (2021) Vitamins E and C do not effectively inhibit low density lipoprotein oxidation by ferritin at lysosomal pH. Free Radical Research, 55 (5). pp. 525-534. ISSN 1071-5762 doi: 10.1080/10715762.2021.1964494

Rathnayake, K. M., Weech, M. ORCID: https://orcid.org/0000-0003-1738-877X, Lovegrove, J. A. ORCID: https://orcid.org/0000-0001-7633-9455 and Jackson, K. G. ORCID: https://orcid.org/0000-0002-0070-3203 (2021) Glu298Asp (rs1799983) polymorphism influences postprandial vascular reactivity and the insulin response to meals of varying fat composition in postmenopausal women: findings from the randomized, controlled DIVAS-2 study. Journal of Nutrition, 151 (4). pp. 848-856. ISSN 1541-6100 doi: 10.1093/jn/nxaa394

Sahli, K. A., Flora, G. D., Sasikumar, P., Maghrabi, A. H., Holbrook, L., AlOuda, S. K., Elgheznawy, A., Sage, T., Stainer, A. R., Adiyaman, R., AboHassan, M., Crescente, M., Kriek, N., Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517, Bye, A. P. ORCID: https://orcid.org/0000-0002-2061-2253, Unsworth, A. J., Jones, C. I. ORCID: https://orcid.org/0000-0001-7537-1509, McGuffin, L. J. ORCID: https://orcid.org/0000-0003-4501-4767 and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 (2021) Structural, functional and mechanistic insights uncover the fundamental role of orphan connexin-62 in platelets. Blood, 137 (6). pp. 830-843. ISSN 0006-4971 doi: 10.1182/blood.2019004575

Simoes Gaspar, R. and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 (2021) Thiol isomerases orchestrate thrombosis and haemostasis. Antioxidants & Redox Signaling, 35 (13). ISSN 1523-0864 doi: 10.1089/ars.2021.0086

Simoes Gaspar, R., Sage, T., Little, G., Kriek, N., Pula, G. and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 (2021) Protein disulphide isomerase and NADPH oxidase 1 cooperate to control platelet function and are associated with cardiometabolic disease risk factors. Antioxidants, 10 (3). 497. ISSN 2076-3921 doi: 10.3390/antiox10030497

Simões Gaspar, R. (2021) Investigation of how redox processes regulate platelet function in health and disease. PhD thesis, University of Reading. doi: 10.48683/1926.00107568

Sowa, M. A. (2021) Artificial lipid membranes to study the platelet CLEC-2-podoplanin interaction. PhD thesis, University of Reading. doi: 10.48683/1926.00109189

Taylor, K. A. ORCID: https://orcid.org/0000-0002-4599-7727, Little, G. and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 (2021) Mind the gap: connexins and pannexins in platelet function. Platelets, 32 (7). pp. 888-894. ISSN 0953-7104 doi: 10.1080/09537104.2021.1902971

Unsworth, A. J., Bye, A. P. ORCID: https://orcid.org/0000-0002-2061-2253, Sage, T., Gaspar, R. S., Eaton, N., Drew, C., Stainer, A., Kriek, N., Volberding, P. J., Hutchinson, J. L., Riley, R., Jones, S., Mundell, S. J., Cui, W., Falet, H. and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 (2021) Anti-platelet properties of Pim kinase inhibition is mediated through disruption of thromboxane A2 receptor signalling. Haematologica, 106 (7). ISSN 1592-8721 doi: 10.3324/haematol.2019.223529

Vavouraki, N. ORCID: https://orcid.org/0000-0003-2581-4935, Tomkins, J. E. ORCID: https://orcid.org/0000-0003-3010-6634, Kara, E. ORCID: https://orcid.org/0000-0001-5428-6743, Houlden, H., Hardy, J., Tindall, M. J., Lewis, P. A. ORCID: https://orcid.org/0000-0003-4537-0489 and Manzoni, C. (2021) Integrating protein networks and machine learning for disease stratification in the Hereditary Spastic Paraplegias. iScience, 24 (5). 102484. ISSN 2589-0042 doi: 10.1016/j.isci.2021.102484

Vogtschmidt, Y. D., Raben, A., Faber, I., de Wilde, C., Lovegrove, J. A. ORCID: https://orcid.org/0000-0001-7633-9455, Givens, D. I. ORCID: https://orcid.org/0000-0002-6754-6935, Pfeiffer, A. F. H. and Soedamah-Muthu, S. S. (2021) Is protein the forgotten ingredient: effects of higher compared to lower protein diets on cardiometabolic risk factors. A systematic review and meta-analysis of randomised controlled trials. Atherosclerosis, 328. pp. 124-135. ISSN 0021-9150 doi: 10.1016/j.atherosclerosis.2021.05.011

2020

Alboaklah, H. K.M. and Leake, D. ORCID: https://orcid.org/0000-0002-1742-6134 (2020) Effect of vitamin E on low density lipoprotein oxidation at lysosomal pH. Free Radical Research, 54 (8-9). pp. 574-584. ISSN 1071-5762 doi: 10.1080/10715762.2020.1817912

Baker, E. J., Valenzuela, C. A., van Dooremalen, W. T. M., Martinez-Fernandez, L., Yaqoob, P. ORCID: https://orcid.org/0000-0002-6716-7599, Miles, E. A. and Calder, P. C. (2020) Gamma-linolenic and pinolenic acids exert anti-inflammatory effects in cultured human endothelial cells through their elongation products. Molecular Nutrition and Food Research, 64 (20). 2000382. ISSN 1613-4133 doi: 10.1002/mnfr.202000382

Bhatti, S. N. ORCID: https://orcid.org/0000-0002-3919-8312, Fan, L. M., Collins, A. and Li, J.-M. ORCID: https://orcid.org/0000-0002-3294-3818 (2020) Exploration of alcohol consumption behaviours and health-related influencing factors of young adults in the UK. International Journal of Environmental Research and Public Health, 17 (17). 6282. ISSN 1660-4601 doi: 10.3390/ijerph17176282

Bye, A. P. ORCID: https://orcid.org/0000-0002-2061-2253, Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 and Mahaut-Smith, M. P. (2020) Ca2+ waves coordinate purinergic receptor–evoked integrin activation and polarization. Science Signaling, 13 (615). eaav7354. ISSN 1937-9145 doi: 10.1126/scisignal.aav7354

Darling, T. K., Schenk, M. P., Zhou, C., Maloba, F. M., Mimche, P. N., Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352, Jobe, S. M. and Lamb, T. J. (2020) Platelet alpha-granules contribute to organ-specific pathologies in a mouse model of severe malaria. Blood Advances, 4 (1). pp. 1-8. ISSN 2473-9529 doi: 10.1182/bloodadvances.2019000773

Fallaize, R., Weech, M. ORCID: https://orcid.org/0000-0003-1738-877X, Zenun Franco, R., Kehlbacher, A., Hwang, F. ORCID: https://orcid.org/0000-0002-3243-3869 and Lovegrove, J. ORCID: https://orcid.org/0000-0001-7633-9455 (2020) The eNutri app: using diet quality indices to deliver automated personalised nutrition advice. Agro Food Industry Hi-Tech, 31 (2). ISSN 1722-6996

Fan, L. M., Collins, A., Geng, L. and Li, J.-M. ORCID: https://orcid.org/0000-0002-3294-3818 (2020) Impact of unhealthy lifestyle on cardiorespiratory fitness and heart rate recovery of medical science students. BMC Public Health, 20 (1). 1012. ISSN 1471-2458 doi: 10.1186/s12889-020-09154-x

Ferreira, P., Bozbas, E., Tannetta, D., Alroqaiba, N., Zhou, R., Crawley, J., Gibbins, J. ORCID: https://orcid.org/0000-0002-0372-5352, Jones, C. ORCID: https://orcid.org/0000-0001-7537-1509, Ahnstrom, J. and Yaqoob, P. ORCID: https://orcid.org/0000-0002-6716-7599 (2020) Mode of induction of platelet-derived extracellular vesicles is a critical determinant of their phenotype and function. Scientific Reports, 10 (1). 18061. ISSN 2045-2322 doi: 10.1038/s41598-020-73005-3

Gaspar, R. S., da Silva, S. A., Stapleton, J., Fontelles, J. L. d., Sousa, H. R., Chagas, V. T., Alsufyani, S., Trostchansky, A., Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 and Paes, A. M. (2020) Myricetin, the main flavonoid in Syzygium cumini leaf, is a novel inhibitor of platelet thiol isomerases PDI and ERp5. Frontiers in Pharmacology, 10. 1678. ISSN 1663-9812 doi: 10.3389/fphar.2019.01678

Koutsos, A., Riccadonna, S., Ulaszewska, M., Franceschi, P., Trošt, K., Galvin, A., Braune, T., Fava, F., Perenzoni, D., Mattivi, F., Tuohy, K. and Lovegrove, J. A. ORCID: https://orcid.org/0000-0001-7633-9455 (2020) Two apples a day lower serum cholesterol and improve cardiometabolic biomarkers in mildly hypercholesterolemic adults: a randomized, controlled, crossover trial. American Journal of Clinical Nutrition, 111 (2). pp. 307-318. ISSN 1938-3207 doi: 10.1093/ajcn/nqz282

Liu, F., Fan, L. M., Michael, N. and Li, J.-M. ORCID: https://orcid.org/0000-0002-3294-3818 (2020) In vivo and in silico characterization of apocynin in reducing organ oxidative stress: a pharmacokinetic and pharmacodynamic study. Pharmacology Research & Perspectives, 8 (4). e00635. ISSN 2052-1707 doi: 10.1002/prp2.635

Livingstone, K. M., Celis-Morales, C., Navas-Carretero, S., San-Cristobal, R., Forster, H., Woolhead, C., O’Donovan, C. B., Moschonis, G., Manios, Y., Traczyk, I., Gundersen, T. E., Drevon, C. A., Marsaux, C. F. M., Fallaize, R., Macready, A. ORCID: https://orcid.org/0000-0003-0368-9336, Daniel, H., Saris, W. H. M., Lovegrove, J. ORCID: https://orcid.org/0000-0001-7633-9455, Gibney, M., Gibney, E. R., Walsh, M., Brennan, L., Martinez, J. A. and Mathers, J. C. (2020) Characteristics of participants who benefit most from personalised nutrition: findings from the pan-European Food4Me randomized controlled trial. British Journal of Nutrition, 123 (12). pp. 1396-1405. ISSN 1475-2662 doi: 10.1017/S0007114520000653

Maghrabi, A. H. A. and McGuffin, L. J. ORCID: https://orcid.org/0000-0003-4501-4767 (2020) Estimating the quality of 3D protein models using the ModFOLD7 server. In: Daisuke, K. (ed.) Protein Structure Prediction. Methods in Molecular Biology, 2165. Springer, pp. 69-81. ISBN 978-1-0716-0708-4 doi: 10.1007/978-1-0716-0708-4_4 (Protein Structure Prediction)

Martyanov, A. A., Balabin, F. A., Dunster, J. L. ORCID: https://orcid.org/0000-0001-8986-4902, Panteleev, M. A., Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 and Sveshnikov, A. N. (2020) Control of platelet CLEC-2-mediated activation by receptor clustering and tyrosine kinase signalling. Biophysical Journal, 118 (11). ISSN 0006-3495 doi: 10.1016/j.bpj.2020.04.023

Steenson, S., Shojaee-Moradie, F., Whyte, M. B., Jackson, K. G. ORCID: https://orcid.org/0000-0002-0070-3203, Lovegrove, J. A. ORCID: https://orcid.org/0000-0001-7633-9455, Fielding, B. A. and Umpleby, A. M. (2020) The effect of fructose feeding on intestinal triacylglycerol production and de novo fatty acid synthesis in humans. Nutrients, 12 (6). 1781. ISSN 2072-6643 doi: 10.3390/nu12061781

Tomkins, J. E., Ferrari, R., Vavouraki, N., Hardy, J., Lovering, R. C., Lewis, P. A., McGuffin, L. J. ORCID: https://orcid.org/0000-0003-4501-4767 and Manzoni, C. (2020) PINOT: an intuitive resource for integrating protein-protein interactions. Cell Communication and Signaling, 18 (92). ISSN 1478-811X doi: 10.1186/s12964-020-00554-5

Vallance, T. M. (2020) Role of bacterial lipopolysaccharides in the modulation of platelet and megakaryocyte function. PhD thesis, University of Reading. doi: 10.48683/1926.00108666

Vasilopoulou, D., Markey, O., Kliem, K. E. ORCID: https://orcid.org/0000-0002-0058-8225, Fagan, C. C. ORCID: https://orcid.org/0000-0002-2101-8694, Grandison, A. S., Humphries, D. J., Todd, S. ORCID: https://orcid.org/0000-0002-9981-923X, Jackson, K. G. ORCID: https://orcid.org/0000-0002-0070-3203, Givens, D. I. ORCID: https://orcid.org/0000-0002-6754-6935 and Lovegrove, J. A. ORCID: https://orcid.org/0000-0001-7633-9455 (2020) Reformulation initiative for partial replacement of saturated with unsaturated fats in dairy foods attenuates the increase in LDL cholesterol and improves flow-mediated dilatation compared with conventional dairy: the randomized, controlled REplacement of SaturatEd fat in dairy on Total cholesterol (RESET) study. The American Journal of Clinical Nutrition, 111 (4). pp. 739-748. ISSN 1938-3207 doi: 10.1093/ajcn/nqz344

lopes Pires, M. E., Ahmed, N. S., Vara, D., Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352, Pula, G. and Pugh, N. (2020) Zinc regulates reactive oxygen species generation in platelets. Platelets, 32 (3). pp. 368-377. ISSN 0953-7104 doi: 10.1080/09537104.2020.1742311

2019

Adiyaman, R. and McGuffin, L. J. ORCID: https://orcid.org/0000-0003-4501-4767 (2019) Methods for the refinement of protein structure 3D models. International Journal of Molecular Sciences, 20 (9). 2301. ISSN 1422-0067 doi: 10.3390/ijms20092301

Ahmad, F. and Leake, D. S. ORCID: https://orcid.org/0000-0002-1742-6134 (2019) Lysosomal oxidation of LDL alters lysosomal pH, induces senescence and increases secretion of pro-inflammatory cytokines in human macrophages. Journal of Lipid Research, 60. pp. 98-110. ISSN 1539-7262 doi: 10.1194/jlr.M088245

AlOuda, S. K. (2019) Role of the collagen molecular chaperone heat shock protein (HSP) 47 in platelet-collagen interaction. PhD thesis, University of Reading. doi: 10.48683/1926.00085394

Celis-Morales, C., Livingstone, K. M., Petermann, F., Navas-Carretero, S., San-Cristobal, R., O’Donovan, C. B., Moschonis, G., Manios, Y., Traczyk, I., Drevon, C. A., Daniel, H., Marsaux, C. F., Saris, W. H., Fallaize, R., Macready, A. L. ORCID: https://orcid.org/0000-0003-0368-9336, Lovegrove, J. A. ORCID: https://orcid.org/0000-0001-7633-9455, Gibney, M., Gibney, E. R., Walsh, M., Brennan, L., Martinez, A. and Mathers, J. C. (2019) Frequent nutritional feedback, personalized advice, and behavioral changes: findings from the European Food4Me internet-based RCT. American Journal of Preventive Medicine, 57 (2). pp. 209-219. ISSN 0749-3797 doi: 10.1016/j.amepre.2019.03.024

Cheng, J., Choe, M.‐H., Elofsson, A., Han, K.‐S., Hou, J., Maghrabi, A. H. A., McGuffin, L. J. ORCID: https://orcid.org/0000-0003-4501-4767, Menéndez‐Hurtado, D., Olechnovič, K., Schwede, T., Studer, G., Uziela, K., Venclovas, Č. and Wallner, B. (2019) Estimation of model accuracy in CASP13. Proteins: Structure, Function, and Bioinformatics. ISSN 0887-3585 doi: 10.1002/prot.25767

Cucurull-Sanchez, L., Chappell, M. J., Chelliah, V., Amy Cheung, S. Y., Derks, G., Penney, M., Phipps, A., Malik-Sheriff, R. S., Timmis, J., Tindall, M. J., van der Graaf, P. H., Vicini, P. and Yates, J. W. T. (2019) Best practices to maximize the use and reuse of quantitative and systems pharmacology models: recommendations from the United Kingdom quantitative and systems pharmacology network. CPT: Pharmacometrics & Systems Pharmacology, 8 (5). pp. 259-272. ISSN 2163-8306 doi: 10.1002/psp4.12381

Fan, L. M., Geng, L., Cahill-Smith, S., Liu, F., Douglas, G., Mckenzie, C.-A., Smith, C., Brooks, G., Channon, K. M. and Li, J.-m. ORCID: https://orcid.org/0000-0002-3294-3818 (2019) Nox2 contributes to age-related oxidative damage to neurons and the cerebral vasculature. The Journal of Clinical Investigation, 129 (8). pp. 3374-3386. ISSN 1558-8238 doi: 10.1172/JCI125173

Flora, G. D., Sahli, K. A., Sasikumar, P., Holbrook, L.-M., Stainer, A. R., Alouda, S. K., Crescente, M., Sage, T., Unsworth, A. J. and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 (2019) Non-genomic effects of the Pregnane X Receptor negatively regulate platelet functions, thrombosis and haemostasis. Scientific Reports, 9 (1). 17210. ISSN 2045-2322 doi: 10.1038/s41598-019-53218-x

Hobbs, D. A., Givens, D. I. ORCID: https://orcid.org/0000-0002-6754-6935 and Lovegrove, J. A. ORCID: https://orcid.org/0000-0001-7633-9455 (2019) Yogurt consumption is associated with higher nutrient intake, diet quality and favourable metabolic profile in children: a cross-sectional analysis using data from years 1–4 of the National diet and Nutrition Survey, UK. European Journal of Nutrition, 58 (1). pp. 409-422. ISSN 1436-6215 doi: 10.1007/s00394-017-1605-x

Macwan, A. S., Boknas, N., Ntzouni, M. P., Ramstrom, S., Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352, Faxalv, L. and Lindahl, T. L. (2019) Gradient-dependent inhibition of stimulatory signaling from platelet G protein-coupled receptors. Haematologica, 104 (7). pp. 1482-1492. ISSN 1592-8721 doi: 10.3324/haematol.2018.205815

McGuffin, L. J. ORCID: https://orcid.org/0000-0003-4501-4767, Adiyaman, R., Maghrabi, A. H. A., Shuid, A. N., Brackenridge, D. A., Nealon, J. O. and Philomina, L. S. (2019) IntFOLD: an integrated web resource for high performance protein structure and function prediction. Nucleic Acids Research. gkz322. ISSN 1362-4962 doi: 10.1093/nar/gkz322

Meijles, D. N., Zoumpoulidou, G., Markou, T., Rostron, K. A., Patel, R., Lay, K., Handa, B. S., Wong, B., Sugden, P. H. and Clerk, A. ORCID: https://orcid.org/0000-0002-5658-0708 (2019) The cardiomyocyte "redox rheostat": Redox signalling via the AMPK-mTOR axis and regulation of gene and protein expression balancing survival and death. Journal of molecular and cellular cardiology, 129. pp. 118-129. ISSN 1095-8584 doi: 10.1016/j.yjmcc.2019.02.006

Navas-Carretero, S., San-Cristobal, R., Livingstone, K. M., Celis-Morales, C., Marsaux, C. F., Macready, A. L. ORCID: https://orcid.org/0000-0003-0368-9336, Fallaize, R., O’Donovan, C. B., Forster, H., Woolhead, C., Moschonis, G., Lambrinou, C. P., Jarosz, M., Manios, Y., Daniel, H., Gibney, E. R., Brennan, L., Walsh, M. C., Drevon, C. A., Gibney, M., Saris, W. H. M., Lovegrove, J. A. ORCID: https://orcid.org/0000-0001-7633-9455, Mathers, J. C. and Martinez, J. A. (2019) Higher vegetable protein consumption, assessed by an isoenergetic macronutrient exchange model, is associated with a lower presence of overweight and obesity in the web-based Food4me European study. International Journal of Food Sciences and Nutrition, 70 (2). pp. 240-253. ISSN 1465-3478 doi: 10.1080/09637486.2018.1492524

Rathnayake, K. M., Weech, M. ORCID: https://orcid.org/0000-0003-1738-877X, Jackson, K. G. ORCID: https://orcid.org/0000-0002-0070-3203 and Lovegrove, J. A. ORCID: https://orcid.org/0000-0001-7633-9455 (2019) Impact of the apolipoprotein E (epsilon) genotype on cardiometabolic risk markers and responsiveness to acute and chronic dietary fat manipulation. Nutrients, 11 (9). 2044. ISSN 2072-6643 doi: 10.3390/nu11092044

Salamah, M. (2019) The role of formyl peptide receptors in the regulation of platelet function. PhD thesis, University of Reading. doi: 10.48683/1926.00084407

Stainer, A., Sasikumar, P., Bye, A. ORCID: https://orcid.org/0000-0002-2061-2253, Unsworth, A., Holbrook, L., Tindall, M., Lovegrove, J. ORCID: https://orcid.org/0000-0001-7633-9455 and Gibbins, J. ORCID: https://orcid.org/0000-0002-0372-5352 (2019) Quercetin and its methylated metabolites possess anti-thrombotic properties that interact with aspirin to enhance its anti-platelet effects. TH Open, 3 (3). e244-e258. ISSN 2512-9465 doi: 10.1055/s-0039-1694028

Stainer, A. R., Sasikumar, P., Bye, A. P. ORCID: https://orcid.org/0000-0002-2061-2253, Unsworth, A. P., Holbrook, L. M., Tindall, M., Lovegrove, J. A. ORCID: https://orcid.org/0000-0001-7633-9455 and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 (2019) The metabolites of the dietary flavonoid quercetin possess potent antithrombotic activity, and interact with aspirin to enhance antiplatelet effects. TH Open, 3 (3). e244-e258. ISSN 2512-9465 doi: 10.1055/s-0039-1694028

Unsworth, A. J., Bombik, I., Pinto-Fernandez, A., McGouran, J. F., Konietzny, R., Zahedi, R. P., Watson, S. P., Kessler, B. M. and Pears, C. J. (2019) Human platelet protein ubiquitylation and changes following GPVI activation. Thrombosis and Haemostasis, 119 (1). pp. 104-116. ISSN 0340-6245 doi: 10.1055/s-0038-1676344

Unsworth, A. J., Bye, A. P. ORCID: https://orcid.org/0000-0002-2061-2253, Kriek, N., Sage, T., Osborne, A. A., Donaghy, D. and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 (2019) Cobimetinib and trametinib inhibit platelet MEK but do not cause platelet dysfunction. Platelets, 30 (6). pp. 762-772. ISSN 0953-7104 doi: 10.1080/09537104.2018.1514107

Ward, J. P., Franks, S. J., Tindall, M. J., King, J. R., Curtis, A. and Evans, G. S. (2019) Mathematical modelling of contact dermatitis from nickel and chromium. Journal of Mathematical Biology, 79 (2). pp. 595-630. ISSN 0303-6812 doi: 10.1007/s00285-019-01371-2

Wen, Y., Ahmad, F., Mohri, Z., Weinberg, P. D. and Leake, D. S. ORCID: https://orcid.org/0000-0002-1742-6134 (2019) Cysteamine inhibits lysosomal oxidation of low density lipoprotein in human macrophages and reduces atherosclerosis in mice. Atherosclerosis, 291. pp. 9-18. ISSN 0021-9150 doi: 10.1016/j.atherosclerosis.2019.09.019

Williams, H., Mellows, B., Mitchell, R., Sfyri, P., Layfield, H., Salamah, M., Vaiyapuri, R., Collins-Hooper, H., Bicknell, A., Matsakas, A., Patel, K. and Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517 (2019) Mechanisms underpinning the permanent muscle damage induced by snake venom metalloprotease. PLoS Neglected Tropical Diseases, 13 (1). e0007041. ISSN 1935-2735 doi: 10.1371/journal.pntd.0007041

Zhou, N., Jiang, Y., Bergquist, T. R., Lee, A. J., Kacsoh, B. Z., Crocker, A. W., Lewis, K. A., Georghiou, G., Nguyen, H. N., Hamid, M. N., Davis, L., Dogan, T., Atalay, V., Rifaioglu, A. S., Dalkiran, A., Cetin-Atalay, R., Zhang, C., Hurto, R. L., Freddolino, P. L., Zhang, Y., Bhat, P., Supek, F., Fernández, J. M., Gemovic, B., Perovic, V. R., Davidović, R. S., Sumonja, N., Veljkovic, N., Asgari, E., Mofrad, M. R. K., Profiti, G., Savojardo, C., Martelli, P. L., Casadio, R., Boecker, F., Kahanda, I., Thurlby, N., McHardy, A. C., Renaux, A., Saidi, R., Gough, J., Freitas, A. A., Antczak, M., Fabris, F., Wass, M. N., Hou, J., Cheng, J., Hou, J., Wang, Z., Romero, A. E., Paccanaro, A., Yang, H., Goldberg, T., Zhao, C., Holm, L., Törönen, P., Medlar, A. J., Zosa, E., Borukhov, I., Novikov, I., Wilkins, A., Lichtarge, O., Chi, P.-H., Tseng, W.-C., Linial, M., Rose, P. W., Dessimoz, C., Vidulin, V., Dzeroski, S., Sillitoe, I., Das, S., Lees, J. G., Jones, D. T., Wan, C., Cozzetto, D., Fa, R., Torres, M., Vesztrocy, A. W., Rodriguez, J. M., Tress, M. L., Frasca, M., Notaro, M., Grossi, G., Petrini, A., Re, M., Valentini, G., Mesiti, M., Roche, D. B., Reeb, J., Ritchie, D. W., Aridhi, S., Alborzi, S. Z., Devignes, M.-D., Emily Koo, D. C., Bonneau, R., Gligorijević, V., Barot, M., Fang, H., Toppo, S., Lavezzo, E., Falda, M., Berselli, M., Tosatto, S. C. E., Carraro, M., Piovesan, D., Rehman, H. U., Mao, Q., Zhang, S., Vucetic, S., Black, G. S., Jo, D., Larsen, D. J., Omdahl, A. R., Sagers, L. W., Suh, E., Dayton, J. B., McGuffin, L. ORCID: https://orcid.org/0000-0003-4501-4767, Brackenridge, D. A., Babbitt, P. C., Yunes, J. M., Fontana, P., Zhang, F., Zhu, S., You, R., Zhang, Z., Dai, S., Yao, S., Tian, W., Cao, R., Chandler, C., Amezola, M., Johnson, D., Chang, J.-M., Liao, W.-H., Liu, Y.-W., Pascarelli, S., Frank, Y., Hoehndorf, R., Kulmanov, M., Boudellioua, I., Politano, G., Di Carlo, S., Benso, A., Hakala, K., Ginter, F., Mehryary, F., Kaewphan, S., Björne, J., Moen, H., Tolvanen, M. E. E., Salakoski, T., Kihara, D., Jain, A., Šmuc, T., Altenhoff, A., Ben-Hur, A., Rost, B., Brenner, S. E., Orengo, C. A., Jeffery, C. J., Bosco, G., Hogan, D. A., Martin, M. J., O’Donovan, C., Mooney, S. D., Greene, C. S., Radivojac, P. and Friedberg, I. (2019) The CAFA challenge reports improved protein function prediction and new functional annotations for hundreds of genes through experimental screens. Genome Biology, 20 (1). 244. ISSN 1474-760X doi: 10.1186/s13059-019-1835-8

2018

Ahmad, F. and Leake, D. ORCID: https://orcid.org/0000-0002-1742-6134 (2018) Antioxidants inhibit low density lipoprotein oxidation less at lysosomal pH: a possible explanation as to why the clinical trials of antioxidants might have failed. Chemistry and Physics of Lipids, 213. pp. 13-24. ISSN 0009-3084 doi: 10.1016/j.chemphyslip.2018.03.001

Barrese, V., Stott, J. B., Figueiredo, H. B., Aubdool, A. A., Hobbs, A. J., Jepps, T. A., McNeish, A. and Greenwood, I. A. (2018) Angiotensin II promotes KV7.4 channels degradation through reduced interaction with HSP90 (heat shock protein 90). Hypertension, 71 (6). pp. 1091-1100. ISSN 1524-4563 doi: 10.1161/HYPERTENSIONAHA.118.11116

Bye, A. P. ORCID: https://orcid.org/0000-0002-2061-2253 and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 (2018) Move along, nothing to see here: Btk inhibitors stop platelets sticking to plaques. Journal of Thrombosis and Haemostasis, 16 (8). pp. 1461-1463. ISSN 1538-7933 doi: 10.1111/jth.14201

Bye, A. P. ORCID: https://orcid.org/0000-0002-2061-2253, Unsworth, A. J. and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 (2018) Screening and high-throughput platelet assays. In: Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 and Mahaut-Smith, M. (eds.) Platelets and Megakaryocytes: Volume 4, Advanced Protocols and Perspectives. Humana Press, New York, pp. 81-94. ISBN 9781493985845 doi: 10.1007/978-1-4939-8585-2_5

Dede, E., Tindall, M. J., Cherrie, J. W., Hankin, S. and Collins, C. (2018) Physiologically-based pharmacokinetic and toxicokinetic models for estimating human exposure to five toxic elements through oral ingestion. Environmental toxicology and pharmacology, 57. pp. 104-114. ISSN 1872-7077 doi: 10.1016/j.etap.2017.12.003

Dunster, J. L. ORCID: https://orcid.org/0000-0001-8986-4902, Panteleev, M. A., Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 and Sveshnikova, A. N. (2018) Mathematical techniques for understanding platelet regulation and the development of new pharmacological approaches. In: Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 and Mahaut-Smith, M. (eds.) Platelets and Megakaryocytes: Volume 4, Advanced Protocols and Perspectives. Methods in Molecular Biology, 1812. Humana Press, New York, pp. 255-279. ISBN 9781493985845 doi: 10.1007/978-1-4939-8585-2_15

Dustin, M. L. and Pollitt, A. Y. ORCID: https://orcid.org/0000-0001-8706-5154 (2018) The study of platelet receptors using artificial lipid bilayers. In: Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 and Mahaut-Smith, M. (eds.) Platelets and Megakaryocytes: Volume 4, Advanced Protocols and Perspectives. Methods in Molecular Biology, 1812. Humana Press, New York, pp. 127-137. ISBN 9781493985845 doi: 10.1007/978-1-4939-8585-2_8

Edgington, M. P. and Tindall, M. J. (2018) Mathematical analysis of the Escherichia coli chemotaxis signalling pathway. Bulletin of Mathematical Biology, 80 (4). pp. 758-787. ISSN 1522-9602 doi: 10.1007/s11538-018-0400-z

Elofsson, A., Joo, K., Keasar, C., Lee, J., Maghrabi, A. H. A., Manavalan, B., McGuffin, L. J. ORCID: https://orcid.org/0000-0003-4501-4767, Ménendez Hurtado, D., Mirabello, C., Pilstål, R., Sidi, T., Uziela, K. and Wallner, B. (2018) Methods for estimation of model accuracy in CASP12. Proteins: Structure, Function, and Bioinformatics, 86. pp. 361-373. ISSN 1097-0134 doi: 10.1002/prot.25395

Fallaize, R. and Lovegrove, J. ORCID: https://orcid.org/0000-0001-7633-9455 (2018) Nutrition in marginalised groups. In: Bonner, A. (ed.) Social Determinants of Health: An Interdisciplinary Approach to Social Inequality and Well-Being. Policy Press, Bristol, pp. 41-53. ISBN 9781447336860

Fallaize, R., Livingstone, K. M., Celis-Morales, C., Macready, A. L. ORCID: https://orcid.org/0000-0003-0368-9336, San-Cristobal, R., Navas-Carretero, S., Marsaux, C. F. M., O’Donovan, C. B., Kolossa, S., Moschonis, G., Walsh, M. C., Gibney, E. R., Brennan, L., Bouwman, J., Manios, Y., Jarosz, M., Martinez, J. A., Daniel, H., Saris, W. H. M., Gundersen, T. E., Drevon, C. A., Gibney, M. J., Mathers, J. C. and Lovegrove, J. A. ORCID: https://orcid.org/0000-0001-7633-9455 (2018) Association between diet-quality scores, adiposity, total cholesterol and markers of nutritional status in European adults: findings from the Food4Me study. Nutrients, 10 (1). pp. 49-64. ISSN 2072-6643 doi: 10.3390/nu10010049

Fekete, A. A., Giromini, C., Chatzidiakou, Y., Givens, D. I. ORCID: https://orcid.org/0000-0002-6754-6935 and Lovegrove, J. A. ORCID: https://orcid.org/0000-0001-7633-9455 (2018) Whey protein lowers systolic blood pressure and Ca-caseinate reduces serum TAG after a high-fat meal in mildly hypertensive adults. Scientific Reports, 8. 5026. ISSN 2045-2322 doi: 10.1038/s41598-018-23333-2

Flora, G. D. (2018) Non-genomic effects of the Pregnane X Receptor (PXR) and Retinoid X Receptor (RXR) in platelets. PhD thesis, University of Reading. doi: 10.17864/1926.80709

Fuentos, E., Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352, Holbrook, L. M. and Palomo, I. (2018) NADPH oxidase 2 (NOX2): a key target of oxidative stress-mediated platelet activation and thrombosis. Trends in Cardiovascular Medicine, 28 (7). pp. 429-434. ISSN 1050-1738 doi: 10.1016/j.tcm.2018.03.001

Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 and Mahaut-Smith, M., eds. (2018) Platelets and Megakaryocytes. Volume 4, Advanced Protocols and Perspectives. Methods in Molecular Biology, 1812. Humana Press, pp304. ISBN 9781493985845 doi: 10.1007/978-1-4939-8585-2

Griffin, B. A. and Lovegrove, J. A. ORCID: https://orcid.org/0000-0001-7633-9455 (2018) Butter increases high-density lipoprotein functional capacity: is this compensation for its adverse effect on serum low-density lipoprotein cholesterol? Journal of Nutrition, 148 (7). pp. 1069-1070. ISSN 1541-6100 doi: 10.1093/jn/nxy086

Griffin, B. A., Walker, C. G., Jebb, S. A., Moore, C., Frost, G. S., Goff, L., Sanders, T. A. B., Lewis, F., Griffin, M., Gitau, R. and Lovegrove, J. A. ORCID: https://orcid.org/0000-0001-7633-9455 (2018) APOE4 genotype exerts greater benefit in lowering plasma cholesterol and apolipoprotein B than wild type (E3/E3), after replacement of dietary saturated fats with low glycaemic index carbohydrates. Nutrients, 10 (10). 1524. ISSN 2072-6643 doi: 10.3390/nu10101524

Guo, J., Jackson, K. G. ORCID: https://orcid.org/0000-0002-0070-3203, Givens, D. I. ORCID: https://orcid.org/0000-0002-6754-6935 and Lovegrove, J. A. ORCID: https://orcid.org/0000-0001-7633-9455 (2018) Reply to TR Hill and I Kyriazakis. Journal of Nutrition, 148 (4). p. 665. ISSN 1541-6100 doi: 10.1093/jn/nxy010

Keasar, C., McGuffin, L. J. ORCID: https://orcid.org/0000-0003-4501-4767, Wallner, B., Chopra, G., Adhikari, B., Bhattacharya, D., Blake, L., Bortot, L. O., Cao, R., Dhanasekaran, B. K., Dimas, I., Faccioli, R. A., Faraggi, E., Ganzynkowicz, R., Ghosh, S., Ghosh, S., Giełdoń, A., Golon, L., He, Y., Heo, L., Hou, J., Khan, M., Khatib, F., Khoury, G. A., Kieslich, C., Kim, D. E., Krupa, P., Lee, G. R., Li, H., Li, J., Lipska, A., Liwo, A., Maghrabi, A. H. A., Mirdita, M., Mirzaei, S., Mozolewska, M. A., Onel, M., Ovchinnikov, S., Shah, A., Shah, U., Sidi, T., Sieradzan, A. K., Ślusarz, M., Ślusarz, R., Smadbeck, J., Tamamis, P., Trieber, N., Wirecki, T., Yin, Y., Zhang, Y., Bacardit, J., Baranowski, M., Chapman, N., Cooper, S., Defelicibus, A., Flatten, J., Koepnick, B., Popović, Z., Zaborowski, B., Baker, D., Cheng, J., Czaplewski, C., Delbem, A. C. B., Floudas, C., Kloczkowski, A., Ołdziej, S., Levitt, M., Scheraga, H., Seok, C., Söding, J., Vishveshwara, S., Xu, D. and Crivelli, S. N. (2018) An analysis and evaluation of the WeFold collaborative for protein structure prediction and its pipelines in CASP11 and CASP12. Scientific Reports, 8 (1). 9939. ISSN 2045-2322 doi: 10.1038/s41598-018-26812-8

Limbu, R., Cottrell, G. S. ORCID: https://orcid.org/0000-0001-9098-7627 and McNeish, A. J. (2018) Characterisation of the vasodilation effects of DHA and EPA, n-3 PUFAs (fish oils), in rat aorta and mesenteric resistance arteries. PLoS ONE, 13 (2). e0192484. ISSN 1932-6203 doi: 10.1371/journal.pone.0192484

Lovegrove, J. ORCID: https://orcid.org/0000-0001-7633-9455 (2018) 30-Second Nutrition. 30 Second. Ivy Press, London, pp160. ISBN 9781782405535

Lovegrove, J. ORCID: https://orcid.org/0000-0001-7633-9455 (2018) Hugh Macdonald Sinclair. In: 30-second Nutrition. 30 Second. Ivy Press, London, United Kingdom, pp. 130-131. ISBN 9781782405535

Lovegrove, J. ORCID: https://orcid.org/0000-0001-7633-9455 (2018) Milk and dairy. In: 30-Second Nutrition. 30 Second. Ivy Press, London, United Kingdom, pp. 60-61. ISBN 9781782405535

Lovegrove, J. ORCID: https://orcid.org/0000-0001-7633-9455 and Griffin, B. (2018) Dietary fats and heart disease. In: 30-Second Nutrition. 30 Second. Ivy Press, London, United Kingdom, pp. 100-101. ISBN 9781782405535

Macready, A. ORCID: https://orcid.org/0000-0003-0368-9336, Fallaize, R., Butler, L. T., Ellis, J. A., Kuznesof, S., Frewer, L. J., Celis-Morales, C., Livingstone, K. M., Araújo-Soares, V., Fischer, A. R. H., Stewart-Knox, B. J., Mathers, J. C. and Lovegrove, J. A. ORCID: https://orcid.org/0000-0001-7633-9455 (2018) Application of behavior change techniques in a personalized nutrition Electronic Health intervention study: protocol for the web-based Food4Me randomized controlled trial. JMIR Research Protocols, 7 (4). e87. ISSN 1929-0748 doi: 10.2196/resprot.8703

Maldonado, E. M., Fisher, C. P., Mazzatti, D. J., Barber, A. L., Tindall, M. J., Plant, N. J., Kierzek, A. M. and Moore, J. B. (2018) Multi-scale, whole-system models of liver metabolic adaptation to fat and sugar in non-alcoholic fatty liver disease. NPJ Systems Biology and Applications, 4. 33. ISSN 2056-7189 doi: 10.1038/s41540-018-0070-3

Mazet, F. and Fry, M. J. (2018) Precise quantification of platelet proteins and their phosphorylation states. In: Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 and Mahaut-Smith, M. (eds.) Platelets and Megakaryocytes: Volume 4, Advanced Protocols and Perspectives. Humana Press, New York, pp. 113-125. ISBN 9781493985845 doi: 10.1007/978-1-4939-8585-2_7

McGuffin, L. ORCID: https://orcid.org/0000-0003-4501-4767, Shuid, A. N., Kempster, R., Maghrabi, A. H.A., Nealon, J. O., Salehe, B. R., Atkins, J. D. and Roche, D. B. (2018) Accurate template-based modeling in CASP12 using the IntFOLD4-TS, ModFOLD6, and ReFOLD methods. Proteins: Structure, Function, and Bioinformatics, 86. pp. 335-344. ISSN 0887-3585 doi: 10.1002/prot.25360

Molica, F., Figueroa, X. F., Kwak, B. R., Isakson, B. E. and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 (2018) Connexins and pannexins in vascular function and disease. International Journal of Molecular Sciences, 19 (6). 1663. ISSN 1422-0067 doi: 10.3390/ijms19061663

Ojo, O. O. and Leake, D. S. ORCID: https://orcid.org/0000-0002-1742-6134 (2018) Low density lipoprotein oxidation by ferritin at lysosomal pH. Chemistry and Physics of Lipids, 217. pp. 51-57. ISSN 0009-3084 doi: 10.1016/j.chemphyslip.2018.09.016

Palmer, C., Peri, F., Neumann, F., Ahmad, F., Leake, D. S. ORCID: https://orcid.org/0000-0002-1742-6134 and Pirianov, G. (2018) The synthetic glycolipid-based TLR4 antagonist FP7 negatively regulates in vitro and in vivo haematopoietic and non-haematopoietic vascular TLR4 signalling. Innate Immunity, 24 (7). pp. 411-421. ISSN 1753-4267 doi: 10.1177/1753425918798904

Pool, F., Currie, R., Sweby, P. K. ORCID: https://orcid.org/0009-0003-8488-0251, Salazar, J. D. and Tindall, M. J. (2018) A mathematical model of the mevalonate cholesterol biosynthesis pathway. Journal of Theoretical Biology, 443. pp. 157-176. ISSN 0022-5193 doi: 10.1016/j.jtbi.2017.12.023

Pool, F., Sweby, P. K. ORCID: https://orcid.org/0009-0003-8488-0251 and Tindall, M. J. (2018) An integrated mathematical model of cellular cholesterol biosynthesis and lipoprotein metabolism. Processes, 6 (8). 134. ISSN 2227-9717 doi: 10.3390/pr6080134

Rathnayake, K. M., Weech, M. ORCID: https://orcid.org/0000-0003-1738-877X, Jackson, K. G. ORCID: https://orcid.org/0000-0002-0070-3203 and Lovegrove, J. A. ORCID: https://orcid.org/0000-0001-7633-9455 (2018) Meal fatty acids have differential effects on postprandial blood pressure and biomarkers of endothelial function but not vascular reactivity in postmenopausal women in the Randomized Controlled Dietary Intervention and VAScular function (DIVAS)-2 Study. Journal of Nutrition, 148 (3). pp. 348-357. ISSN 1541-6100 doi: 10.1093/jn/nxx042

Rathnayake, K., Weech, M. ORCID: https://orcid.org/0000-0003-1738-877X, Jackson, K. ORCID: https://orcid.org/0000-0002-0070-3203 and Lovegrove, J. ORCID: https://orcid.org/0000-0001-7633-9455 (2018) Impact of meal fatty acid composition on postprandial lipaemia, vascular function and blood pressure in postmenopausal women. Nutrition Research Reviews, 31 (2). pp. 193-203. ISSN 0954-4224 doi: 10.1017/S0954422418000033

Roche, D. B., Buenavista, M. T. and McGuffin, L. J. ORCID: https://orcid.org/0000-0003-4501-4767 (2018) Protein structure prediction and structural annotation of proteomes. In: Encyclopedia of Biophysics. Springer. doi: 10.1007/978-3-642-35943-9_418-1

Salamah, M. F., Ravishankar, D., Kodji, X., Moraes, L. A., Williams, H. F., Vallance, T. M., Albadawi, D. A., Vaiyapuri, R., Watson, K. ORCID: https://orcid.org/0000-0002-9987-8539, Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352, Brain, S. D., Perretti, M. and Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517 (2018) The endogenous antimicrobial cathelicidin LL37 induces platelet activation and augments thrombus formation. Blood Advances, 2 (21). pp. 2973-2985. ISSN 2473-9529 doi: 10.1182/bloodadvances.2018021758

Sasikumar, P., AlOuda, K. S., Kaiser, W. J., Holbrook, L. M., Kriek, N., Unsworth, A. J., Bye, A. P. ORCID: https://orcid.org/0000-0002-2061-2253, Sage, T., Ushioda, R. W., Nagata, K., Farndale, R. W. and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 (2018) The chaperone protein HSP47: a platelet collagen binding protein that contributes to thrombosis and haemostasis. Journal of Thrombosis and Haemostasis, 16 (5). pp. 946-959. ISSN 1538-7933 doi: 10.1111/jth.13998

Snowden, T. J., van der Graaf, P. H. and Tindall, M. J. (2018) Model reduction in mathematical pharmacology: integration, reduction and linking of PBPK and systems biology models. Journal of Pharmacokinetics and Pharmacodynamics, 45 (4). pp. 537-555. ISSN 1573-8744 doi: 10.1007/s10928-018-9584-y

Stefanini, L., Lee, R. H., Paul, D. S., O'Shaughnessy, E. C., Ghalloussi, D., Jones, C. I. ORCID: https://orcid.org/0000-0001-7537-1509, Boulaftali, Y., Poe, K. O., Piatt, R., Kechele, D. O., Caron, K. M., Hahn, K. M., Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 and Bergmeier, W. (2018) Functional redundancy between RAP1 isoforms in murine platelet production and function. Blood, 132 (18). pp. 1951-1962. ISSN 0006-4971 doi: 10.1182/blood-2018-03-838714

Tindall, M. J. (2018) System insights into hemostasis: open questions and the role of mathematical modelling: comment on “Modeling thrombosis in silico: Frontiers, challenges, unresolved problems and milestones” by A.V. Belyaev et al. Physics of Life Reviews, 26-27. pp. 106-107. ISSN 1571-0645 doi: 10.1016/j.plrev.2018.06.011

Unsworth, A. J., Flora, G. D. and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 (2018) Non-genomic effects of nuclear receptors: insights from the anucleate platelet. Cardiovascular Research, 114 (5). pp. 645-655. ISSN 0008-6363 doi: 10.1093/cvr/cvy044

2017

Albani, V., Celis-Morales, C., O'Donovan, C. B., Walsh, M. C., Woolhead, C., Forster, H., Fallaize, R., Macready, A. L. ORCID: https://orcid.org/0000-0003-0368-9336, Marsaux, C. F.M., Navas-Carretero, S., San-Cristoba, R., Kolossa, S., Mavrogianni, C., Lambrinou, C. P., Moschonis, G., Godlewska, M., Surwillo, A., Traczyk, I., Gundersen, T. E., Drevon, C. A., Daniel, H., Manios, Y., Martinez, J. A., Saris, W. H.M., Lovegrove, J. A. ORCID: https://orcid.org/0000-0001-7633-9455, Gibney, M. J., Gibney, E. R., Mathers, J. C., Adamson, A. J. and Brennan, L. (2017) Within-person reproducibility and sensitivity to dietary change of C15:0 and C17:0 levels in dried blood spots: data from the European Food4Me Study. Molecular Nutrition & Food Research, 61 (10). 1700142. ISSN 1613-4125 doi: 10.1002/mnfr.201700142

Barrese, V., Cidad, P., Yueng, S. Y., Lopez-Lopez, J. R., McNeish, A., Ohya, S., Perez-Garcia, M. T. and Greenwood, I. A. (2017) Proliferative role of Kv11 channels in murine arteries. Frontiers in Physiology, 8. 500. ISSN 1664-042X doi: 10.3389/fphys.2017.00500

Bye, A. P. ORCID: https://orcid.org/0000-0002-2061-2253, Unsworth, A. J., Desborough, M. J., Hildyard, C. A. T., Appleby, N., Bruce, D., Kriek, N., Nock, S. H., Sage, T., Hughes, C. E. ORCID: https://orcid.org/0000-0002-9790-5820 and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 (2017) Severe platelet dysfunction in NHL patients receiving ibrutinib is absent in patients receiving acalabrutinib. Blood Advances, 1 (26). pp. 2610-2623. ISSN 2473-9529 doi: 10.1182/bloodadvances.2017011999

Calabuig-Navarro, M. V., Jackson, K. G. ORCID: https://orcid.org/0000-0002-0070-3203, Kemp, C. F., Leake, D. S. ORCID: https://orcid.org/0000-0002-1742-6134, Walden, C. M., Lovegrove, J. A. ORCID: https://orcid.org/0000-0001-7633-9455 and Minihane, A. M. (2017) A randomized trial and novel SPR technique identifies altered lipoprotein-LDL receptor binding as a mechanism underlying elevated LDL-cholesterol in APOE4s. Scientific Reports, 7. 44119. ISSN 2045-2322 doi: 10.1038/srep44119

Fallaize, R., Carvalho-Wells, A. L., Tierney, A. C., Marin, C., Kieć-Wilk, B., Dembińska-Kieć, A., Drevon, C. A., DeFoort, C., Lopez-Miranda, J., Risérus, U., Saris, W. H., Blaak, E. E., Roche, H. M. and Lovegrove, J. A. ORCID: https://orcid.org/0000-0001-7633-9455 (2017) APOE genotype influences insulin resistance, apolipoprotein CII and CIII according to plasma fatty acid profile in the Metabolic Syndrome. Scientific Reports, 7 (1). 6274. ISSN 2045-2322 doi: 10.1038/s41598-017-05802-2

Fallaize, R., Seale, J. V., Mortin, C., Armstrong, L. and Lovegrove, J. A. ORCID: https://orcid.org/0000-0001-7633-9455 (2017) Dietary intake, nutritional status and mental wellbeing of homeless adults in Reading, UK. British Journal of Nutrition, 118 (9). pp. 707-714. ISSN 0007-1145 doi: 10.1017/S0007114517002495

Fan, L. M., Cahill-Smith, S., Geng, L., Du, J., Brooks, G. and Li, J.-m. ORCID: https://orcid.org/0000-0002-3294-3818 (2017) Aging-associated metabolic disorder induces Nox2 activation and oxidative damage of endothelial function. Free Radical Biology and Medicine, 108. pp. 940-951. ISSN 0891-5849 doi: 10.1016/j.freeradbiomed.2017.05.008

Giromini, C., Fekete, Á. A., Givens, D. I. ORCID: https://orcid.org/0000-0002-6754-6935, Baldi, A. and Lovegrove, J. A. ORCID: https://orcid.org/0000-0001-7633-9455 (2017) Short-communication: a comparison of the in vitro angiotensin-1-converting enzyme inhibitory capacity of dairy and plant protein supplements. Nutrients, 9 (12). 1352. ISSN 2072-6643 doi: 10.3390/nu9121352

Grimaldi, K. A., van Ommen, B., Ordovas, J. M., Parnell, L. D., Mathers, J. C., Bendik, I., Brennan, L., Celis-Morales, C., Cirillo, E., Daniel, H., de Kok, B., El-Sohemy, A., Fairweather-Tait, S. J., Fallaize, R., Fenech, M., Ferguson, L. R., Gibney, E. R., Gibney, M., Gjelstad, I. M. F., Kaput, J., Karlsen, A. S., Kolossa, S., Lovegrove, J. ORCID: https://orcid.org/0000-0001-7633-9455, Macready, A. L. ORCID: https://orcid.org/0000-0003-0368-9336, Marsaux, C. F. M., Martinez, J. A., Milagro, F., Navas-Carretero, S., Roche, H. M., Saris, W. H. M., Traczyk, I., van Kranen, H., Verschuren, L., Virgili, F., Weber, P. and Bouwman, J. (2017) Proposed guidelines to evaluate scientific validity and evidence for genotype-based dietary advice. Genes & Nutrition, 12. 35. ISSN 1865-3499 doi: 10.1186/s12263-017-0584-0

Guo, J., Astrup, A., Lovegrove, J. A. ORCID: https://orcid.org/0000-0001-7633-9455, Gijsbers, L., Givens, I. ORCID: https://orcid.org/0000-0002-6754-6935 and Soedamah-Muthu, S. S. (2017) Milk and dairy consumption and risk of cardiovascular diseases and all-cause mortality: dose-response meta-analysis of prospective cohort studies. European Journal of Epidemiology, 32 (4). pp. 269-287. ISSN 0393-2990 doi: 10.1007/s10654-017-0243-1

Guo, S., Cockcroft, J. R., Elwood, P. C., Pickering, J. E., Lovegrove, J. A. ORCID: https://orcid.org/0000-0001-7633-9455 and Givens, D. I. ORCID: https://orcid.org/0000-0002-6754-6935 (2017) Vitamin D intake and risk of CVD and all-cause mortality: evidence from the Caerphilly Prospective Cohort Study. Public Health Nutrition, 20 (15). pp. 2744-2753. ISSN 1368-9800 doi: 10.1017/S1368980017001732

Ilkan, Z., Wright, J. R., Goodall, A. H., Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352, Jones, C. I. ORCID: https://orcid.org/0000-0001-7537-1509 and Mahaut-Smith, M. P. (2017) Evidence for shear-mediated Ca2+ entry through mechanosensitive cation channels in human platelets and a megakaryocytic cell line. The Journal of Biological Chemistry, 292 (22). pp. 9204-9217. ISSN 1083-351X doi: 10.1074/jbc.M116.766196

Jackson, K. G. ORCID: https://orcid.org/0000-0002-0070-3203, Lockyer, S., Carvalho-Wells, A. L., Williams, C. M., Minihane, A. M. and Lovegrove, J. A. ORCID: https://orcid.org/0000-0001-7633-9455 (2017) APOLIPOPROTEIN E (epsilon) genotype has a greater impact on apoB-48 than apoB-100 responses to dietary fat manipulation- insights from the SATgenε study. Molecular Nutrition and Food Research, 61 (4). 1600688. ISSN 1613-4133 doi: 10.1002/mnfr.201600688

Lopes Pires, M. E., Clarke, S. R., Marcondes, S. and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 (2017) Lipopolysaccharide potentiates platelet responses via toll-like receptor 4-stimulated Akt-Erk-PLA2 signalling. PLoS ONE, 12 (11). e0186981. ISSN 1932-6203 doi: 10.1371/journal.pone.0186981

Lovegrove, J. A. ORCID: https://orcid.org/0000-0001-7633-9455, Stainer, A. and Hobbs, D. A. (2017) Role of flavonoids and nitrates in cardiovascular health. Proceedings of the Nutrition Society, 76 (2). pp. 83-65. ISSN 0029-6651 doi: 10.1017/S0029665116002871

Maghrabi, A. H. A. and McGuffin, L. J. ORCID: https://orcid.org/0000-0003-4501-4767 (2017) ModFOLD6: an accurate web server for the global and local quality estimation of 3D protein models. Nucleic Acids Research, 45 (W1). W416-W421. ISSN 0305-1048 doi: 10.1093/nar/gkx332

Markey, O., Souroullas, K., Fagan, C. C. ORCID: https://orcid.org/0000-0002-2101-8694, Kliem, K. E. ORCID: https://orcid.org/0000-0002-0058-8225, Vasilopoulou, D., Jackson, K. G. ORCID: https://orcid.org/0000-0002-0070-3203, Humphries, D. J., Grandison, A. S., Givens, D. I. ORCID: https://orcid.org/0000-0002-6754-6935, Lovegrove, J. A. ORCID: https://orcid.org/0000-0001-7633-9455 and Methven, L. (2017) Consumer acceptance of dairy products with a saturated fatty acid-reduced, monounsaturated fatty acid-enriched content. Journal of Dairy Science, 100 (10). pp. 7953-7966. ISSN 0022-0302 doi: 10.3168/jds.2016-12057

Markey, O., Vasilopoulou, D., Kliem, K. E. ORCID: https://orcid.org/0000-0002-0058-8225, Koulman, A., Fagan, C. C. ORCID: https://orcid.org/0000-0002-2101-8694, Summerhill, K., Wang, L. Y., Grandison, A. S., Humphries, D. J., Todd, S. ORCID: https://orcid.org/0000-0002-9981-923X, Jackson, K. G. ORCID: https://orcid.org/0000-0002-0070-3203, Givens, D. I. ORCID: https://orcid.org/0000-0002-6754-6935 and Lovegrove, J. A. ORCID: https://orcid.org/0000-0001-7633-9455 (2017) Plasma phospholipid fatty acid profile confirms compliance to a novel saturated fat-reduced, monounsaturated fat-enriched dairy product intervention in adults at moderate cardiovascular risk: a randomized controlled trial. Nutrition journal, 16 (1). 33. ISSN 1475-2891 doi: 10.1186/s12937-017-0249-2

Mertens, E., Markey, O., Geleijnse, J. M., Givens, D. I. ORCID: https://orcid.org/0000-0002-6754-6935 and Lovegrove, J. A. ORCID: https://orcid.org/0000-0001-7633-9455 (2017) Dietary patterns in relation to cardiovascular disease incidence and risk markers in a middle-aged British male population: data from the Caerphilly prospective study. Nutrients, 9 (1). 75. ISSN 2072-6643 doi: 10.3390/nu9010075

Nealon, J. O., Philomina, L. S. and McGuffin, L. J. ORCID: https://orcid.org/0000-0003-4501-4767 (2017) Predictive and experimental approaches for elucidating protein–protein interactions and quaternary structures. International Journal of Molecular Sciences, 18 (12). 2623. ISSN 1422-0067 doi: 10.3390/ijms18122623

Onetti, Y., Dantas, A. Y., Perez, B., McNeish, A. J., Vila, E. and Jimenez-Altyayo, F. (2017) Peroxynitrate formed during a transient episode of brain ischemia increases endothelium-derived hyperpolarization-type dilations in thromboxane/prostaglandin receptor stimulated rat cerebral arteries. Acta Physiologica, 220 (1). pp. 150-166. ISSN 1748-1716 doi: 10.1111/apha.12809

Ravishankar, D., Salamah, M., Attina, A., Pothi, R., Vallance, T. M., Javed, M., Williams, H. F., Alzahrani, E. M. S., Kabova, E., Vaiyapuri, R., Shankland, K. ORCID: https://orcid.org/0000-0001-6566-0155, Gibbins, J. ORCID: https://orcid.org/0000-0002-0372-5352, Strohfeldt, K., Greco, F., Osborn, H. M. I. ORCID: https://orcid.org/0000-0002-0683-0457 and Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517 (2017) Ruthenium-conjugated chrysin analogues modulate platelet activity, thrombus formation and haemostasis with enhanced efficacy. Scientific Reports, 7. 5738. ISSN 2045-2322 doi: 10.1038/s41598-017-05936-3

Salehe, B. R., Jones, C. I. ORCID: https://orcid.org/0000-0001-7537-1509, Di Fatta, G. and McGuffin, L. ORCID: https://orcid.org/0000-0003-4501-4767 (2017) RAPIDSNPs: A new computational pipeline for rapidly identifying key genetic variants reveals previously unidentified SNPs that are significantly associated with individual platelet responses. PLoS ONE, 12 (4). e0175957. ISSN 1932-6203 doi: 10.1371/journal.pone.0175957

San-Cristobal, R., Navas-Carretero, S., Celis-Morales, C., Livingstone, K., Stewart-Knox, B., Rankin, A., Macready, A. ORCID: https://orcid.org/0000-0003-0368-9336, Fallaize, R., O'Donovan, C., Forster, H., Woolhead, C., Walsh, M., Lambrinou, C., Moschonis, G., Manios, Y., Jarosz, M., Daniel, H., Gibney, E., Brennan, L., Gundersen, T., Drevon, C., Gibney, M., Marsaux, C., Saris, W., Lovegrove, J. ORCID: https://orcid.org/0000-0001-7633-9455, Frewer, L., Mathers, J. and Martinez, J. (2017) Capturing health and eating status through a nutritional perception screening questionnaire (NPSQ9) in a randomised internet-based personalised nutrition intervention: the Food4Me study. International Journal of Behavioral Nutrition and Physical Activity, 14 (1). 168. ISSN 1479-5868 doi: 10.1186/s12966-017-0624-6

Shuid, A. N., Kempster, R. and McGuffin, L. J. ORCID: https://orcid.org/0000-0003-4501-4767 (2017) ReFOLD: a server for the refinement of 3D protein models guided by accurate quality estimates. Nucleic Acids Research, 45 (W1). W422-W428. ISSN 1362-4962 doi: 10.1093/nar/gkx249

Snowden, T. J., van der Graaf, P. H. and Tindall, M. J. (2017) Methods of model reduction for large-scale biological systems: a survey of current methods and trends. Bulletin of Mathematical Biology, 79 (7). pp. 1449-1486. ISSN 1522-9602 doi: 10.1007/s11538-017-0277-2

Snowden, T. J., van der Graaf, P. H. and Tindall, M. J. (2017) A combined model reduction algorithm for controlled biochemical systems. BMC Systems Biology, 11 (1). 17. ISSN 1752-0509 doi: 10.1186/s12918-017-0397-1

Steenson, S., Umpleby, A. M., Lovegrove, J. A. ORCID: https://orcid.org/0000-0001-7633-9455, Jackson, K. G. ORCID: https://orcid.org/0000-0002-0070-3203 and Fielding, B. A. (2017) Role of the enterocyte in fructose-induced hypertriglyceridaemia. Nutrients, 9 (4). 349. ISSN 2072-6643 doi: 10.3390/nu9040349

Unsworth, A. J., Flora, G. D., Sasikumar, P., Bye, A. P. ORCID: https://orcid.org/0000-0002-2061-2253, Sage, T., Kriek, N., Crescente, M. and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 (2017) RXR ligands negatively regulate thrombosis and hemostasis. Arteriosclerosis Thrombosis and Vascular Biology, 37 (5). pp. 812-822. ISSN 1524-4636 doi: 10.1161/ATVBAHA.117.309207

Unsworth, A. J., Kriek, N., Bye, A. P. ORCID: https://orcid.org/0000-0002-2061-2253, Naran, K., Sage, T., Flora, G. D. and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 (2017) PPARγ agonists negatively regulate αIIbβ3 integrin outside-in signalling and platelet function through upregulation of protein kinase A activity. Journal of Thrombosis and Haemostasis, 15 (2). pp. 356-369. ISSN 1538-7933 doi: 10.1111/jth.13578

Webb, M., Tracey, M., Harwin, W. ORCID: https://orcid.org/0000-0002-3928-3381, Tokatli, O., Hwang, F. ORCID: https://orcid.org/0000-0002-3243-3869, Johnson, R., Barrett, N. ORCID: https://orcid.org/0000-0001-9123-1100 and Jones, C. ORCID: https://orcid.org/0000-0001-7537-1509 (2017) The potential for haptic-enabled interaction to support collaborative learning in school biology. In: Resta, P. and Smith, S. (eds.) Proceedings of Society for Information Technology & Teacher Education International Conference 2017. Association for the Advancement of Computing in Education (AACE), Chesapeake VA, pp. 927-935. ISBN 9781939797278

Whiteley, M. S., Dos Santos, S. J., Lee, C. T. and Li, J.-m. ORCID: https://orcid.org/0000-0002-3294-3818 (2017) Mechanochemical ablation causes endothelial and medial damage to the vein wall resulting in deeper penetration of sclerosant compared with sclerotherapy alone in extrafascial great saphenous vein using an ex vivo model. Journal of Vascular Surgery: Venous and Lymphatic Disorders, 5 (3). pp. 370-377. ISSN 2213-3348 doi: 10.1016/j.jvsv.2016.12.009

Williams, H. F., Vaiyapuri, R., Gajjeraman, P., Hutchinson, G., Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352, Bicknell, A. B. and Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517 (2017) Challenges in diagnosing and treating snakebites in a rural population of Tamil Nadu, India: the views of clinicians. Toxicon, 130. pp. 44-46. ISSN 0041-0101 doi: 10.1016/j.toxicon.2017.02.025

Zenun Franco, R., Alawadhi, B., Fallaize, R., Lovegrove, J. A. ORCID: https://orcid.org/0000-0001-7633-9455 and Hwang, F. ORCID: https://orcid.org/0000-0002-3243-3869 (2017) A web-based graphical food frequency assessment system: design, development and usability metrics. Journal of Medical Internet Research Human Factors, 4 (2). e13. ISSN 2292-9495 doi: 10.2196/humanfactors.7287

2016

Ampatzoglou, A., Williams, C. L., Atwal, K. K., Maidens, C. M., Ross, A. B., Thielecke, F., Jonnalagadda, S. S., Kennedy, O. B. ORCID: https://orcid.org/0000-0003-3885-4872 and Yaqoob, P. ORCID: https://orcid.org/0000-0002-6716-7599 (2016) Effects of increased wholegrain consumption on immune and inflammatory markers in healthy low habitual wholegrain consumers. European Journal of Nutrition, 55 (1). pp. 183-195. ISSN 1436-6215 doi: 10.1007/s00394-015-0836-y

Bye, A. P. ORCID: https://orcid.org/0000-0002-2061-2253, Unsworth, A. J. and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 (2016) Platelet signaling: a complex interplay between inhibitory and activatory networks. Journal of Thrombosis and Haemostasis, 14 (5). pp. 918-930. ISSN 1538-7933 doi: 10.1111/jth.13302

Connolly, M. L., Tzounis, X., Tuohy, K. M. and Lovegrove, J. A. ORCID: https://orcid.org/0000-0001-7633-9455 (2016) Hypocholesterolemic and prebiotic effects of a whole-grain oat-based granola breakfast cereal in a cardio-metabolic "At Risk" population. Frontiers in Microbiology, 7. 1675. ISSN 1664-302X doi: 10.3389/fmicb.2016.01675

Crescente, M., Pluthero, F. G., Li, L., Lo, R. W., Walsh, T. G., Schenk, M. P., Holbrook, L. M., Loureiro, S. ORCID: https://orcid.org/0009-0000-8886-6893, Ali, M. S., Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517, Falet, H., Jones, I. M. ORCID: https://orcid.org/0000-0002-7738-2516, Poole, A. W., Kahr, W. H. A. and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 (2016) Intracellular trafficking, localization, and mobilization of platelet-borne thiol isomerases. Arteriosclerosis Thrombosis and Vascular Biology, 36 (6). pp. 1164-1173. ISSN 1079-5642 doi: 10.1161/ATVBAHA.116.307461

Dong, H., Rendeiro, C., Kristek, A., Sargent, L. J., Saunders, C., Harkness, L., Rowland, I., Jackson, K. G. ORCID: https://orcid.org/0000-0002-0070-3203, Spencer, J. P. E. ORCID: https://orcid.org/0000-0003-2931-7274 and Lovegrove, J. A. ORCID: https://orcid.org/0000-0001-7633-9455 (2016) Addition of orange pomace to orange juice attenuates the increases in peak glucose and insulin concentrations after sequential meal ingestion in men with elevated cardiometabolic risk. Journal of Nutrition, 146 (6). pp. 1197-1203. ISSN 1541-6100 doi: 10.3945/jn.115.226001

Forster, H., Walsh, M. C., O'Donovan, C. B., Woolhead, C., McGirr, C., Daly, E. J., O'Riordan, R., Celis-Morales, C., Fallaize, R., Macready, A. L. ORCID: https://orcid.org/0000-0003-0368-9336, Marsaux, C. F.M., Navas-Carretero, S., San-Cristobal, R., Kolossa, S., Hartwig, K., Mavrogianni, C., Tsirigoti, L., Lambrinou, C. P., Godlewska, M., Surwillo, A., Gjelstad, I. M. F., Drevon, C. A., Manios, Y., Traczyk, I., Martinez, J. A., Saris, W. H. M., Daniel, H., Lovegrove, J. A. ORCID: https://orcid.org/0000-0001-7633-9455, Mathers, J. C., Gibney, M. J., Gibney, E. R. and Brenan, L. (2016) A dietary feedback system for the delivery of consistent personalized dietary advice in the web-based multicenter Food4Me study. Journal of Medical Internet Research, 18 (6). e150. ISSN 1438-8871 doi: 10.2196/jmir.5620

Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 (2016) Platelets stop us leaking. Blood, 127 (12). pp. 1528-1529. ISSN 0006-4971 doi: 10.1182/blood-2016-01-692186

Kirwan, L., Walsh, M. C., Brennan, L., Gibney, E. R., Drevon, C. A., Daniel, H., Lovegrove, J. A. ORCID: https://orcid.org/0000-0001-7633-9455, Manios, Y., Martínez, J. A., Saris, W. H., Traczyk, I., Mathers, J. C. and Gibney, M. (2016) Comparison of the portion size and frequency of consumption of 156 foods across seven European countries: insights from the Food4ME study. European Journal of Clinical Nutrition, 70 (5). pp. 642-644. ISSN 0954-3007 doi: 10.1038/ejcn.2015.227

Li, X. and Lovegrove, J. ORCID: https://orcid.org/0000-0001-7633-9455 (2016) Genetics and hyperlipidaemia. In: Lawrence, J., Douglas, P. and Gandy, J. (eds.) Dietetic and nutrition case studies. Wiley-Blackwell, Chichester, pp. 55-61. ISBN 9781118897102

Livingstone, K., Celis-Morales, C., Navas-Carretero, S., San-Cristobal, R., O’Donovan, C., Forster, H., Woolhead, C., Marsaux, C., Macready, A. ORCID: https://orcid.org/0000-0003-0368-9336, Fallaize, R., Kolossa, S., Tsirigoti, L., Lambrinou, C., Moschonis, G., Godlewska, M., Surwiłło, A., Drevon, C., Manios, Y., Traczyk, I., Gibney, E., Brennan, L., Walsh, M., Lovegrove, J. ORCID: https://orcid.org/0000-0001-7633-9455, Martinez, J., Saris, W., Daniel, H., Gibney, M. and Mathers, J. (2016) Profile of European adults interested in internet-based personalized nutrition: The Food4Me Study. European Journal of Nutrition, 55 (2). pp. 759-769. ISSN 1436-6215 doi: 10.1007/s00394-015-0897-y

Lovegrove, J. A. ORCID: https://orcid.org/0000-0001-7633-9455 and Hobbs, D. A. (2016) Plenary Lecture 2: Milk and dairy produce and CVD: new perspectives on dairy and cardiovascular health. Proceedings of the Nutrition Society, 75 (3). pp. 247-258. ISSN 0029-6651 doi: 10.1017/S002966511600001X

Markey, O., Le Jeurne, J. and Lovegrove, J. A. ORCID: https://orcid.org/0000-0001-7633-9455 (2016) Energy compensation following consumption of sugar-reduced products: a randomized controlled trial. European Journal of Nutrition, 55 (6). pp. 2137-2149. ISSN 1436-6215 doi: 10.1007/s00394-015-1028-5

Marsaux, C. F. M., Celis-Morales, C., Hoonhout, J., Claassen, A., Goris, A., Forster, H., Fallaize, R., Macready, A. L. ORCID: https://orcid.org/0000-0003-0368-9336, Navas-Carretero, S., Kolossa, S., Walsh, M. C., Lambrinou, C.-P., Manios, Y., Godlewska, M., Traczyk, I., Lovegrove, J. A. ORCID: https://orcid.org/0000-0001-7633-9455, Martinez, J. A., Daniel, H., Gibney, M., Mathers, J. C. and Saris, W. H. M. (2016) Objectively measured physical activity in European adults: cross-sectional findings from the Food4Me study. PLoS ONE, 11 (3). e0150902. ISSN 1932-6203 doi: 10.1371/journal.pone.0150902

Meijles, D. N., Fan, L. M., Ghazaly, M. M., Howlin, B., Krönke, M., Brooks, G. and Li, J.-m. ORCID: https://orcid.org/0000-0002-3294-3818 (2016) p22phox C242T SNP inhibits inflammatory oxidative damage to endothelial cells and vessels. Circulation, 133 (24). pp. 2391-2403. ISSN 1524-4539 doi: 10.1161/CIRCULATIONAHA.116.021993

Moraes, L. A., Unsworth, A. J., Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517, Ali, M. S., Sasikumar, P., Sage, T., Flora, G. D., Bye, A. P. ORCID: https://orcid.org/0000-0002-2061-2253, Kriek, N., Dorchies, E., Molendi-Coste, O., Dombrowicz, D., Staels, B., Bishop-Bailey, D. and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 (2016) Farnesoid X Receptor and its ligands inhibit the function of platelets. Arteriosclerosis Thrombosis and Vascular Biology, 36 (12). pp. 2324-2333. ISSN 1524-4636 doi: 10.1161/ATVBAHA.116.308093

Nettleton, J. A., Lovegrove, J. A. ORCID: https://orcid.org/0000-0001-7633-9455, Mensink, R. P. and Schwab, U. (2016) Dietary fatty acids: is it time to change the recommendations. Annals of Nutrition and Metabolism, 68 (4). pp. 249-257. ISSN 1421-9697 doi: 10.1159/000446865

O'Donovan, C. B., Walsh, M. C., Forster, H., Woolhead, C., Celis-Morales, C., Fallaize, R., Macready, A. ORCID: https://orcid.org/0000-0003-0368-9336, Marsaux, C. F. M., Navas-Carretero, S., San-Cristobal, R., Kolossa, S., Mavrogianni, C., Lambrinou, C. P., Moschonis, G., Godlewska, M., Surwillo, A., Bouwman, J., Grimaldi, K., Traczyk, I., Drevon, C. A., Daniel, H., Manios, Y., Martinez, J. A., Saris, W. H. M., Lovegrove, J. A. ORCID: https://orcid.org/0000-0001-7633-9455, Mathers, J. C., Gibney, M. J., Brennan, L. and Gibney, E. R. (2016) The impact of MTHFR 677C → T risk knowledge on changes in folate intake: findings from the Food4Me study. Genes & Nutrition, 11 (1). 25. ISSN 1865-3499 doi: 10.1186/s12263-016-0539-x

Roche, D. B. and McGuffin, L. J. ORCID: https://orcid.org/0000-0003-4501-4767 (2016) In silico identification and characterization of protein-ligand binding sites. In: Computational design of ligand binding proteins. Methods in Molecular Biology, 1414. Springer, pp. 1-21. ISBN 9781493935673 doi: 10.1007/978-1-4939-3569-7_1

Roche, D. B. and McGuffin, L. J. ORCID: https://orcid.org/0000-0003-4501-4767 (2016) Toolbox for protein structure prediction. In: Sanchez-Diaz, A. and Perez, P. (eds.) Yeast Cytokinesis. Methods in Molecular Biology, 1369. Springer, pp. 363-377. ISBN 9781493931453 doi: 10.1007/978-1-4939-3145-3_23

Sahoo, S., Meijles, D. N., Al Ghouleh, I., Tandon, M., Cifuentes-Pagano, E., Sembrat, J., Rojas, M., Goncharova, E. and Pagano, P. J. (2016) MEF2C-MYOCD and leiomodin1 suppression by miRNA-214 promotes smooth muscle cell phenotype switching in pulmonary arterial hypertension. PLoS ONE, 11 (5). e0153780. ISSN 1932-6203 doi: 10.1371/journal.pone.0153780

San-Cristobal, R., Navas-Carretero, S., Milagro, F. I., Riezu-Boj, J. I., Guruceaga, E., Celis-Morales, C., Livingstone, K. M., Brennan, L., Lovegrove, J. A. ORCID: https://orcid.org/0000-0001-7633-9455, Daniel , H., Saris , W. H., Traczyk, I., Manios, Y., Gibney, E. R., Gibney, M. J., Mathers , J. C. and Martinez, J. A. (2016) Gene methylation parallelisms between peripheral blood cells and oral mucosa samples in relation to overweight. Journal of Physiology and Biochemistry, 73 (3). pp. 465-474. ISSN 1877-8755 doi: 10.1007/s13105-017-0560-6

Shatwan, I., Minihane, A.-M., William, C., Lovegrove, J. ORCID: https://orcid.org/0000-0001-7633-9455, Jackson, K. ORCID: https://orcid.org/0000-0002-0070-3203 and Vimaleswaran, K. S. ORCID: https://orcid.org/0000-0002-8485-8930 (2016) Impact of lipoprotein lipase gene polymorphism, S447X, on postprandial triacylglycerol and glucose response to sequential meal ingestion. International Journal of Molecular Sciences, 17 (3). 397. ISSN 1422-0067 doi: 10.3390/ijms17030397

Ulaszewska, M. M., Trost, K., Stanstrup, J., Tuohy, K. M., Franceschi, P., Chong, M. F.-F., George, T., Minihane, A. M., Lovegrove, J. A. ORCID: https://orcid.org/0000-0001-7633-9455 and Mattivi, F. (2016) Urinary metabolomic profiling to identify biomarkers of a flavonoid-rich and flavonoid-poor fruits and vegetables diet: the FLAVURS trial in adults: the FLAVURS trial. Metabolomics, 12 (2). 32. ISSN 1573-3890 doi: 10.1007/s11306-015-0935-z

2015

Ampatzoglou, A., Atwal, K., Maidens, C., Williams, C., Ross, A., Thielecke, F., Jonnalagadda, S., Kennedy, O. ORCID: https://orcid.org/0000-0003-3885-4872 and Yaqoob, P. ORCID: https://orcid.org/0000-0002-6716-7599 (2015) Increased whole grain consumption does not affect blood biochemistry, body composition or gut microbiology in healthy low habitual whole grain consumers. Journal of Nutrition, 145 (2). pp. 215-221. ISSN 1541-6100 doi: 10.3945/jn.114.202176

Armah, C. N., Derdemezis, C., Traka, M. H., Dainty, J. R., Doleman, J. F., Saha, S., Leung, W., Potter, J. F., Lovegrove, J. ORCID: https://orcid.org/0000-0001-7633-9455 and Mithen, R. F. (2015) Diet rich in high glucoraphanin broccoli reduces plasma LDL cholesterol: evidence from randomised controlled trials. Molecular Nutrition & Food Research, 59 (5). pp. 918-926. ISSN 1613-4125 doi: 10.1002/mnfr.201400863

Atkins, J. D., Boateng, S. Y., Sorensen, T. and McGuffin, L. J. ORCID: https://orcid.org/0000-0003-4501-4767 (2015) Disorder prediction methods, their applicability to different protein targets and their usefulness for guiding experimental studies. International Journal of Molecular Sciences, 16 (8). pp. 19040-19054. ISSN 1422-0067 doi: 10.3390/ijms160819040

Bye, A. P. ORCID: https://orcid.org/0000-0002-2061-2253, Unsworth, A. J., Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517, Stainer, A. R., Fry, M. J. and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 (2015) Ibrutinib inhibits platelet integrin αIIbβ3 outside-in signaling and thrombus stability but not adhesion to collagen. Arteriosclerosis Thrombosis and Vascular Biology, 35 (11). pp. 2326-2335. ISSN 1524-4636 doi: 10.1161/ATVBAHA.115.306130

Celis-Morales, C., Livingstone, K. M., Marsaux, C. F., Forster, H., O'Donovan, C. B., Woolhead, C., Macready, A. ORCID: https://orcid.org/0000-0003-0368-9336, Fallaize, R., Navas-Carretero, S., San-Cristobal, R., Kolossa, S., Hartwig, K., Tsirigoti, L., Lambrinou, C. P., Moschonis, G., Godlewska, M., Surwiłło, A., Grimaldi, K., Bouwman, J., Daly, E. J., Akujobi, V., O'Riordan, R., Hoonhout, J., Claassen, A., Hoeller, U., Gundersen, T. E., Kaland, S. E., Matthews, J. N., Manios, Y., Traczyk, I., Drevon, C. A., Gibney, E. R., Brennan, L., Walsh, M. C., Lovegrove, J. ORCID: https://orcid.org/0000-0001-7633-9455, Alfredo Martinez, J., Saris, W. H., Daniel, H., Gibney, M. and Mathers, J. C. (2015) Design and baseline characteristics of the Food4Me study: a web-based randomised controlled trial of personalised nutrition in seven European countries. Genes & Nutrition, 10 (1). 450. ISSN 1865-3499 doi: 10.1007/s12263-014-0450-2

Chouinard-Watkins, R., Conway, V., Minihane, A. M., Jackson, K. G. ORCID: https://orcid.org/0000-0002-0070-3203, Lovegrove, J. A. ORCID: https://orcid.org/0000-0001-7633-9455 and Plourde, M. (2015) Interaction between BMI and APOE genotype is associated with changes in the plasma long-chain-PUFA response to a fish-oil supplement in healthy participants. American Journal of Clinical Nutrition, 102 (2). pp. 505-513. ISSN 0002-9165 doi: 10.3945/ajcn.114.103507

Dunster, J. L. ORCID: https://orcid.org/0000-0001-8986-4902, Mazet, F., Fry, M. J., Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 and Tindall, M. J. (2015) Regulation of early steps of GPVI signal transduction by phosphatases: a systems biology approach. PLoS Computational Biology, 11 (11). e1004589. ISSN 1553-734X doi: 10.1371/journal.pcbi.1004589

Edgington, M. P. and Tindall, M. J. (2015) Understanding the link between single cell and population scale responses of Escherichia coli in differing ligand gradients. Computational and Structural Biotechnology Journal, 13. pp. 528-538. ISSN 2001-0370 doi: 10.1016/j.csbj.2015.09.003

Fallaize, R., Macready, A. L. ORCID: https://orcid.org/0000-0003-0368-9336, Butler, L. T., Ellis, J. A., Berezowska, A., Fischer, A. R. H., Walsch, M. C., Gallagher, C., Stewart-Knox, B. J., Kuznesof, S., Frewer, L. J., Gibney, M. J. and Lovegrove, J. A. ORCID: https://orcid.org/0000-0001-7633-9455 (2015) The perceived impact of the National Health Service on personalised nutrition service delivery among the UK public. British Journal of Nutrition, 113 (8). pp. 1271-1279. ISSN 0007-1145 doi: 10.1017/S0007114515000045

Fekete, Á. A., Givens, D. I. ORCID: https://orcid.org/0000-0002-6754-6935 and Lovegrove, J. A. ORCID: https://orcid.org/0000-0001-7633-9455 (2015) Casein-derived lactotripeptides reduce systolic and diastolic blood pressure in a meta-analysis of randomised clinical trials. Nutrients, 7 (1). pp. 659-681. ISSN 2072-6643 doi: 10.3390/nu7010659

Hoeller, U., Baur, M., Roos, F. F., Brennan, L., Daniel, H., Fallaize, R., Forster, H., Gibney, E. R., Gibney, M., Godlewska, M., Hartwig, K., Kolossa, S., Lambrinou, C.-P., Livingstone, K. M., Lovegrove, J. A. ORCID: https://orcid.org/0000-0001-7633-9455, Macready, A. L. ORCID: https://orcid.org/0000-0003-0368-9336, Manios, Y., Marsaux, C. F. M., Martinez, J. A., Celis-Morales, C., Moschonis, G., Navas-Carretero, S., O Donovan, C. B., San-Cristobal, R., Saris, W. H. M., Surwiłło, A., Traczyk, I., Tsirigoti, L., Walsh, M. C., Woolhead, C., Mathers, J. C. and Weber, P. (2015) Application of dried blood spots to determine vitamin D status in a large nutritional study with unsupervised sampling: the Food4Me project. British Journal of Nutrition, 115 (2). pp. 202-211. ISSN 0007-1145 doi: 10.1017/S0007114515004298

Koutsos, A. and Lovegrove, J. A. ORCID: https://orcid.org/0000-0001-7633-9455 (2015) An apple a day keeps the doctor away: inter-relationship between apple consumption, the gut microbiota and cardio-metabolic disease risk reduction. In: Tuohy, K. and Del Rio, D. (eds.) Diet-microbe interactions in the gut: effects on human health and disease. Academic Press, London, pp. 173-194. ISBN 9780124078253

Koutsos, A., Tuohy, K. M. and Lovegrove, J. ORCID: https://orcid.org/0000-0001-7633-9455 (2015) Apples and cardiovascular health: is the gut microbiota a core consideration? Nutrients, 7 (6). pp. 3959-3998. ISSN 2072-6643 doi: 10.3390/nu7063959

Livingstone, K., Celis-Morales, C., Lara, J., Ashor, A., Lovegrove, J. ORCID: https://orcid.org/0000-0001-7633-9455, Martinez, J., Saris, W., Gibney, M., Manios, Y., Traczyk, I., Drevon, C., Daniel, H., Gibney, E., Brennan, L., Bouwman, J., Grimaldi, K. and Mathers, J. (2015) Associations between FTO genotype and total energy and macronutrients intake: a systematic review and meta-analysis. Obesity Reviews, 16 (8). pp. 666-678. ISSN 1467-789x doi: 10.1111/obr.12290

Lovegrove, J. A. ORCID: https://orcid.org/0000-0001-7633-9455, Hodson, L., Sharma, S., Lanham-New, S. A. and Krebs, J., eds. (2015) Nutrition research methodologies. The Nutrition Society Text Book Series. Wiley Blackwell, Chichester, pp356. ISBN 9781118554678

Mazet, F., Dunster, J. L. ORCID: https://orcid.org/0000-0001-8986-4902, Jones, C. I. ORCID: https://orcid.org/0000-0001-7537-1509, Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517, Tindall, M. J., Fry, M. J. and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 (2015) A high-density immunoblotting methodology for quantification of total protein levels and phosphorylation modifications. Scientific Reports, 5. 16995. ISSN 2045-2322 doi: 10.1038/srep16995

McGuffin, L. J. ORCID: https://orcid.org/0000-0003-4501-4767, Atkins, J. D., Salehe, B. R., Shuid, A. N. and Roche, D. B. (2015) IntFOLD: an integrated server for modelling protein structures and functions from amino acid sequences. Nucleic Acids Research, 43 (W1). W169-W173. ISSN 1362-4962 doi: 10.1093/nar/gkv236