2024

Ablinger, C., Eibl, C., Roznovcova, M., Cottrell, G. S. ORCID: https://orcid.org/0000-0001-9098-7627, Stephens, G. J. ORCID: https://orcid.org/0000-0002-8966-4238 and Obermair, G. J. (2024) The presynaptic α2δ protein family and their therapeutic potential. In: Stephens, G. ORCID: https://orcid.org/0000-0002-8966-4238 and Stevens, E. (eds.) Ion Channels as Targets in Drug Discovery. Springer International Publishing, Cambridge, pp. 57-89. ISBN 9783031521966 doi: https://doi.org/10.1007/978-3-031-52197-3_3

Alboaklah, H. K. M. ORCID: https://orcid.org/0000-0003-0272-5040, McNeish, A. J. ORCID: https://orcid.org/0000-0002-3466-8442 and Leake, D. S. ORCID: https://orcid.org/0000-0002-1742-6134 (2024) Low density lipoprotein oxidized under lysosomal conditions decreases arterial vasodilatation. Free Radical Research. ISSN 1029-2470 doi: https://doi.org/10.1080/10715762.2024.2403038

Bin Haidar, H., Almeida, J. R., Williams, J., Guo, B., Bigot, A., Senthilkumaran, S., Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517 and Patel, K. (2024) Differential effects of the venoms of Russell’s viper and Indian cobra on human myoblasts. Scientific Reports, 14. 3184. ISSN 2045-2322 doi: https://doi.org/10.1038/s41598-024-53366-9

Carden, H., Harper, K. L., Mottram, T. J., Manners, O., Allott, K. L., Dallas, M. L. ORCID: https://orcid.org/0000-0002-5190-0522, Hughes, D. J., Lippiat, J. D., Mankouri, J. and Whitehouse, A. (2024) Kv 1.3-induced hyperpolarization is required for efficient Kaposi’s sarcoma–associated herpesvirus lytic replication. Science Signaling, 17 (845). eadg4124. ISSN 1937-9145 doi: https://doi.org/10.1126/scisignal.adg4124

Chowdhury, A., Fry, B. G., Samuel, S. P., Bhalla, A., Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517, Bhargava, P., Carter, R. W. and Lewin, M. R. (2024) In vitro anticoagulant effects of Bungarus venoms on human plasma which are effectively neutralized by the PLA2-inhibitor varespladib. Toxicon. ISSN 0041-0101 (In Press)

Eyssen, L. E. -A., Ramadurai, S., Abdelkarim, S., Buckle, I., Cornish, K., Lin, H., Jones, A. K., Stephens, G. J. ORCID: https://orcid.org/0000-0002-8966-4238 and Owens, R. J. (2024) From llama to nanobody: a streamlined workflow for the generation of functionalised VHHs. Bio-Protocol, 14 (6). e4962. ISSN 2331-8325 doi: https://doi.org/10.21769/BioProtoc.4962

Feijoo-Coronel, M. L., Mendes, B., Ramírez, D., Peña-Varas, C., Monteros-Silva, N. Q. E. d. l., Proaño-Bolaños, C., Oliveira, L. C. D., Lívio, D. F., Da Silva, J. A., Da Silva, J. M. S. F., Pereira, M. G. A. G., Rodrigues, M. Q. R. B., Teixeira, M. M., Granjeiro, P. A., Patel, K., Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517 and Almeida, J. R. (2024) Antibacterial and antiviral properties of Chenopodin-derived synthetic peptides. Antibiotics, 13 (1). 78. ISSN 2079-6382 doi: https://doi.org/10.3390/antibiotics13010078

Goniotaki, D., Tamagnini, F. ORCID: https://orcid.org/0000-0002-8741-5094, Biasetti, L., Rumpf, S.-L., Troakes, C., Pollack, S. J., Ukwesa, S., Sun, H., Kraev, I., Serpell, L. C., Noble, W., Staras, K. and Hanger, D. P. (2024) Tau-mediated synaptic dysfunction is coupled with HCN channelopathy. Alzheimer's and Dementia: Translational Research and Clinical Interventions, 20 (8). pp. 5629-5646. ISSN 2352-8737 doi: https://doi.org/10.1002/alz.14074

Karunakaran, K. B. (2024) Interactome-based framework to translate disease genetic data into biological and clinical insights. PhD thesis, University of Reading. doi: https://doi.org/10.48683/1926.00119013

Maiarù, M. ORCID: https://orcid.org/0000-0003-0927-6567, Leese, C., Silva-Hucha, S., Fontana-Giusti, S., Tait, L., Tamagnini, F. ORCID: https://orcid.org/0000-0002-8741-5094, Davletov, B. and Hunt, S. P. (2024) Substance P-Botulinum mediates long-term silencing of pain pathways that can be re-instated with a second injection of the construct in mice. The Journal of Pain, 25 (6). 104466. ISSN 1526-5900 doi: https://doi.org/10.1016/j.jpain.2024.01.331

Meng, H., Elliott, A., Mansfield, J., Bailey, M., Frogley, M., Cinque, G., Moger, J., Stone, N., Tamagnini, F. ORCID: https://orcid.org/0000-0002-8741-5094 and Palombo, F. (2024) Identification of tauopathy-associated lipid signatures in Alzheimer’s disease mouse brain using label-free chemical imaging. Communications Biology, 7 (1). 1341. ISSN 2399-3642 doi: https://doi.org/10.1038/s42003-024-07034-3

Mitry, M. M.A., Dallas, M. ORCID: https://orcid.org/0000-0002-5190-0522, Boateng, S. Y., Greco, F. and Osborn, H. M.I. ORCID: https://orcid.org/0000-0002-0683-0457 (2024) Selective activation of prodrugs in breast cancer using metabolic glycoengineering and the tetrazine ligation bioorthogonal reaction. Bioorganic Chemistry, 147. 107304. ISSN 0045-2068 doi: https://doi.org/10.1016/j.bioorg.2024.107304

Papapetropoulos, A., Topouzis, S., Alexander, S. P. H., Cortese-Krott, M., Kendall, D. A., Martemyanov, K. A., Mauro, C., Nagercoil, N., Panettieri Jr, R. A., Patel, H. H., Schulz, R., Stefanska, B., Stephens, G. J. ORCID: https://orcid.org/0000-0002-8966-4238, Teixeira, M. M., Vergnolle, N., Wang, X. and Ferdinandy, P. (2024) Novel drugs approved by the EMA, the FDA, and the MHRA in 2023: a year in review. British Journal of Pharmacology. ISSN 1476-5381 doi: https://doi.org/10.1111/bph.16337

Saghafi, S., Rumbell, T., Gurev, V., Kozloski, J., Tamagnini, F. ORCID: https://orcid.org/0000-0002-8741-5094, Wedgwood, K. C. A. and Diekman, C. O. (2024) Inferring parameters of pyramidal neuron excitability in mouse models of Alzheimer’s disease using biophysical modeling and deep learning. Bulletin of Mathematical Biology, 86 (5). 46. ISSN 1522-9602 doi: https://doi.org/10.1007/s11538-024-01273-5

Salim, A., Chandrasekharuni, G., Almeida, J. R., Vaiyapuri, R., Williams, H. F., Arumugam, S., Senthilkumaran, S., Patel, K., Williams, T., Zsidó, A. N. and Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517 (2024) Snake phobia among the general population of Tamil Nadu, India. PLoS Neglected Tropical Diseases. ISSN 1935-2735 (In Press)

Salim, A., Williams, J., Almeida, J. R., Chandrasekharuni, G., Williams, H. F., Vaiyapuri, R., Vaiyapuri, M., Viswanath, R., Annamalai, T., Patel, K., Thirumalaikolundusubramanian, P., Senthilkumaran, S., Whitaker, R. and Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517 (2024) Challenges in rescuing snakes to protect human lives and promote snake conservation in Tamil Nadu, India. PLoS Neglected Tropical Diseases. ISSN 1935-2735 (In Press)

Senthilkumaran, S., Almeida, J. R., Williams, J., Williams, H., Thirumalaikolundusubramanian, P. and Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517 (2024) Development of squamous cell carcinoma at the bite sites several years following suspected cobra (Naja naja) envenomings. Clinical Toxicology. ISSN 1556-9519 (In Press)

Senthilkumaran, S., Sampath, S., Almeida, J. R. ORCID: https://orcid.org/0000-0002-4637-4468, Williams, J., Williams, H. F., Patel, K., Thirumalaikolundusubramanian, P. and Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517 (2024) Pulmonary thromboembolism following Russell’s viper bites. Toxins, 16 (5). 222. ISSN 2072-6651 doi: https://doi.org/10.3390/toxins16050222

Senthilkumaran, S., Williams, J., Almeida, J. R., Williams, H. F., Patel, K., Thirumalaikolundusubramanian, P. and Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517 (2024) Snakebite-induced reversible cerebral vasoconstriction syndrome: report of three cases. Toxicon, 251. 108161. ISSN 1879-3150 doi: https://doi.org/10.1016/j.toxicon.2024.108161

Skurikhin, E., Ermakova, N., Pan, E., Widera, D. ORCID: https://orcid.org/0000-0003-1686-130X, Sandrikina, L., Pershina, O., Pakhomova, A., Pan, V. Y., Kushlinskii, N., Kubatiev, A., Morozov, S. and Dygai, A. (2024) Effects of reprogrammed splenic CD8+ T-cells in vitro and in mice with spontaneous metastatic Lewis lung carcinoma. BMC Cancer, 24. 522. ISSN 1471-2407 doi: https://doi.org/10.1186/s12885-024-12203-y

Skurikhin, E., Zhukova, M., Ermakova, N., Pan, E., Widera, D. ORCID: https://orcid.org/0000-0003-1686-130X, Sandrikina, L., Kogai, L., Kushlinskii, N., Kubatiev, A., Morozov, S. and Dygai, A. (2024) Age-related features of lung cancer treatment using reprogrammed CD8 positive T cells in mice subjected to injection of Lewis lung carcinoma cells. Thoracic Cancer. ISSN 1759-7714 doi: https://doi.org/10.1111/1759-7714.15426

Stevens, E. B. and Stephens, G. J. ORCID: https://orcid.org/0000-0002-8966-4238 (2024) Ion channels as targets in drug discovery: outlook and perspectives. In: Stephens, G. ORCID: https://orcid.org/0000-0002-8966-4238 and Stevens, E. (eds.) Ion Channels as Targets in Drug Discovery. Springer International Publishing, Cambridge, pp. 1-34. ISBN 9783031521966 doi: https://doi.org/10.1007/978-3-031-52197-3_1

Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517 and Falabella, P., eds. (2024) Venom collection. Scientific Reports. Nature Publishing Group. (In Press) (ISSN: 2045-2322)

Vajaria, R., Davis, D., Thaweepanyaporn, K., Dovey, J., Nasuto, S., Delivopoulos, E. ORCID: https://orcid.org/0000-0001-6156-1133, Tamagnini, F. ORCID: https://orcid.org/0000-0002-8741-5094, Knight, P. ORCID: https://orcid.org/0000-0003-0300-1554 and Vasudevan, N. ORCID: https://orcid.org/0000-0003-4326-3938 (2024) Estrogen and testosterone secretion from the mouse brain. Steroids, 204. 109398. ISSN 1878-5867 doi: https://doi.org/10.1016/j.steroids.2024.109398

Vermeij, W. P., Alyodawi, K., Galen, I. v., Heide, J. L. v. d., Birkisdóttir, M. B., van’t Sant, L. J., Ozinga, R. A., Komninos, D. S.J., Smit, K., Rijksen, Y. M.A., Brandt, R. M.C., Barnhoorn, S., Jaarsma, D., Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517, Ritvos, O., Huber, T. B., Kretz, O. and Patel, K. (2024) Improved health by combining dietary restriction and promoting muscle growth in DNA repair-deficient progeroid mice. Journal of Cachexia, Sarcopenia and Muscle. ISSN 2190-6009 doi: https://doi.org/10.1002/jcsm.13570

Wang, X., Izzo, A. A., Papapetropoulos, A., Alexander, S. P. H., Cortese-Krott, M., Kendall, D. A., Martemyanov, K. A., Mauro, C., Panettieri Jr, R. A., Patel, H. H., Schulz, R., Stefanska, B., Stephens, G. J. ORCID: https://orcid.org/0000-0002-8966-4238, Teixeira, M. M., Vergnolle, N. and Ferdinandy, P. (2024) Natural product pharmacology: the British Journal of Pharmacology perspective. British Journal of Pharmacology. ISSN 1476-5381 doi: https://doi.org/10.1111/bph.17300

Widera, D. ORCID: https://orcid.org/0000-0003-1686-130X (2024) Exploring stem cell therapies: an interview with Darius Widera. Regenerative Medicine. ISSN 1746-076X doi: https://doi.org/10.1080/17460751.2024.2375104

2023

Al-Owais, M. M., Hettiarachchi, N. T., Dallas, M. L. ORCID: https://orcid.org/0000-0002-5190-0522, Scragg, J. L., Lippiat, J. D., Holden, A. V., Steele, D. S. and Peers, C. (2023) Inhibition of the voltage-gated potassium channel Kv1.5 by hydrogen sulfide attenuates remodeling through S-nitrosylation-mediated signaling. Communications Biology, 6. 651. ISSN 2399-3642 doi: https://doi.org/10.1038/s42003-023-05016-5

Asadpour, A., Yahaya, B., Bicknell, K. ORCID: https://orcid.org/0000-0002-5888-1424, Cottrell, G. S. ORCID: https://orcid.org/0000-0001-9098-7627 and Widera, D. ORCID: https://orcid.org/0000-0003-1686-130X (2023) Uncovering the gray zone: mapping the global landscape of direct-to-consumer businesses offering interventions based on secretomes, extracellular vesicles, and exosomes. Stem cell research and therapy, 14 (1). 111. ISSN 1757-6512 doi: https://doi.org/10.1186/s13287-023-03335-2

Bermúdez-Puga, S., Dias, M., Freire de Oliveira, T., Mendonça, C. M. N., Yokomizo de Almeida, S. R., Rozas, E. E., do Nascimento, C. A. O., Mendes, M. A., Oliveira De Souza de Azevedo, P., Almeida, J. R. ORCID: https://orcid.org/0000-0002-4637-4468, Proaño-Bolaños, C. and Oliveira, R. P. d. S. (2023) Dual antibacterial mechanism of [K4K15]CZS-1 against Salmonella Typhimurium: a membrane active and intracellular-targeting antimicrobial peptide. Frontiers in Microbiology, 14. 1320154. ISSN 1664-302X doi: https://doi.org/10.3389/fmicb.2023.1320154

Brady, E. S., Griffiths, J., Andrianova, L., Bielska, M. H., Saito, T., Saido, T. C., Randall, A. D., Tamagnini, F. ORCID: https://orcid.org/0000-0002-8741-5094, Witton, J. and Craig, M. T. (2023) Alterations to parvalbumin-expressing interneuron function and associated network oscillations in the hippocampal – medial prefrontal cortex circuit during natural sleep in AppNL-G-F/NL-G-F mice. Neurobiology of disease, 182. 106151. ISSN 1095-953X doi: https://doi.org/10.1016/j.nbd.2023.106151

Courtenay, M., Gillespie, D. and Lim, R. ORCID: https://orcid.org/0000-0003-1705-1480 (2023) Patterns of GP and nurse independent prescriber prescriptions for antibiotics dispensed in the community in England: a retrospective analysis. Journal of Antimicrobial Chemotherapy, 78 (10). pp. 2544-2553. ISSN 1460-2091 doi: https://doi.org/10.1093/jac/dkad267

Dallas, M. L. ORCID: https://orcid.org/0000-0002-5190-0522 and Bell, D. (2023) Advances in ion channel high throughput screening: where are we in 2023? Expert Opinion on Drug Discovery. ISSN 1746-045X doi: https://doi.org/10.1080/17460441.2023.2294948

Day, C., Silva, J.-P., Munro, R., Baker, T. S., Wolff, C., Bithell, A. and Stephens, G. J. ORCID: https://orcid.org/0000-0002-8966-4238 (2023) Anti-AMPA receptor autoantibodies reduce excitatory currents in rat hippocampal neurons. Pharmaceuticals, 16 (1). 77. ISSN 1424-8247 doi: https://doi.org/10.3390/ph16010077

Fareez, I. M., Liew, F. F., Widera, D. ORCID: https://orcid.org/0000-0003-1686-130X, Mayeen, N. F., Mawya, J., Abu Kasim, N. H. and Haque, N. (2023) Application of platelet-rich plasma as a stem cell treatment - an attempt to clarify a common public misconception. Current Molecular Medicine, 23. ISSN 1875-5666 doi: https://doi.org/10.2174/1566524023666230511152646

Ingrande, J., Patel, H. H., Kendall, D., Stefanska, B., Alexander, S., Bakhle, M., Cirino, G., Docherty, J. R., George, C. H., Insel, P. A., Ji, Y., King, B. F., Lilley, E., Panettieri, R. A., Ramage, A. G., Sobey, C. G., Stanford, S. C., Stephens, G. ORCID: https://orcid.org/0000-0002-8966-4238, Teixeira, M., Vergnolle, N. and Ahluwalia, A. (2023) Guidance for the use and reporting of anaesthetic agents in BJP manuscripts involving work with animals. British Journal of Pharmacology, 180 (3). pp. 255-263. ISSN 0007-1188 doi: https://doi.org/10.1111/bph.15992

Leese, C. ORCID: https://orcid.org/0000-0002-3123-0154, Christmas, C. ORCID: https://orcid.org/0009-0009-5129-9982, Mészáros, J. ORCID: https://orcid.org/0000-0002-8196-9061, Ward, S., Maiaru, M. ORCID: https://orcid.org/0000-0003-0927-6567, Hunt, S. P. and Davletov, B. ORCID: https://orcid.org/0000-0003-4658-3275 (2023) New botulinum neurotoxin constructs for treatment of chronic pain. Life Science Alliance, 6 (6). e202201631. ISSN 2575-1077 doi: https://doi.org/10.26508/lsa.202201631

Long, M. M. ORCID: https://orcid.org/0000-0003-3646-2218, Needs, S. H. ORCID: https://orcid.org/0000-0003-3407-9637 and Edwards, A. D. ORCID: https://orcid.org/0000-0003-2369-989X (2023) Dilution reduces sample matrix effects for rapid, direct, and miniaturised phenotypic antibiotic susceptibility tests for bovine mastitis. Antibiotics, 12 (9). 1363. ISSN 2079-6382 doi: https://doi.org/10.3390/antibiotics12091363

Maiarù, M. ORCID: https://orcid.org/0000-0003-0927-6567, Acton, R. J., Woźniak, E. L., Mein, C. A., Bell, C. G. ORCID: https://orcid.org/0000-0003-4601-1242 and Géranton, S. M. ORCID: https://orcid.org/0000-0002-1659-1285 (2023) A DNA methylation signature in the stress driver gene Fkbp5 indicates a neuropathic component in chronic pain. Clinical Epigenetics, 15. 155. ISSN 1868-7083 doi: https://doi.org/10.1186/s13148-023-01569-8

Mitchell, J. L., Khan, D., Rana, R. H., Kriek, N., Unsworth, A. J., Sage, T., Bye, A. P. ORCID: https://orcid.org/0000-0002-2061-2253, Laffan, M., Shapiro, S., Thakurta, A., Grech, H., Ramasamy, K. and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 (2023) Multiple myeloma and its treatment contribute to increased platelet reactivity. Platelets, 34 (1). 2264940. ISSN 1369-1635 doi: https://doi.org/10.1080/09537104.2023.2264940

Palaniyappan, K., S. M. N. Mydin, R. B. ORCID: https://orcid.org/0000-0001-8971-8809, Widera, D. ORCID: https://orcid.org/0000-0003-1686-130X, Noordin, S. S., Harun, N. H., Wan Eddis Effendy, W. N., Hazan, R. and Sreekantan, S. (2023) Double-edged sword of biofouling potentials associated with haemocompatibility behaviour: titania nanotube arrays for medical implant surface technology. Beni-Suef University Journal of Basic and Applied Sciences, 12 (1). 36. ISSN 2314-8543 doi: https://doi.org/10.1186/s43088-023-00363-y

Panettieri, R. A., Stanford, S. C., Alexander, S., Cirino, G., George, C. H., Insel, P. A., Kendall, D., Ji, Y., Patel, H. H., Sobey, C. G., Stefanska, B., Stephens, G. ORCID: https://orcid.org/0000-0002-8966-4238, Teixeira, M., Vergnolle, N., Ferdinandy, P. and Ahluwalia, A. (2023) BJP recommendations for publishing research on tobacco smoke and environmental tobacco smoke exposure. British Journal of Pharmacology, 180 (12). pp. 1537-1541. ISSN 0007-1188 doi: https://doi.org/10.1111/bph.16089

Richards, N. J., Alqallaf, A., Mitchell, R. D., Parnell, A., Haidar, H. B., Almeida, J. R., Williams, J., Vijayakumar, P., Balogun, A., Matsakas, A., Trim, S. A., Patel, K. and Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517 (2023) Indian ornamental tarantula (Poecilotheria regalis) venom affects myoblast function and causes skeletal muscle damage. Cells, 12 (16). 2074. ISSN 2073-4409 doi: https://doi.org/10.3390/cells12162074

Roosterman, D. and Cottrell, G. S. ORCID: https://orcid.org/0000-0001-9098-7627 (2023) Discovery of a second citric acid cycle complex. Heliyon, 9 (5). e15968. ISSN 24058440 doi: https://doi.org/10.1016/j.heliyon.2023.e15968

Salim, A., Williams, J., Wahab, S. A., Adeshokan, T., Almeida, J. R., Williams, H. F., Vaiyapuri, R., Senthilkumaran, S., Thirumalaikolundusubramanian, P., Patel, K., Baksh, M. F. ORCID: https://orcid.org/0000-0003-3107-8815, Lewin, M. R. and Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517 (2023) Identifying key factors contributing to treatment costs for snakebite envenoming in private tertiary healthcare settings in Tamil Nadu, India. PLoS Neglected Tropical Diseases, 17 (10). e0011699. ISSN 1935-2735 doi: https://doi.org/10.1371/journal.pntd.0011699

Samy, R. P., Mackessy, S. P., Jeyasankar, A., Ponraj, M. R., Franco, O. L., Cooper, M. A., Kandasamy, M., Mohanta, T. K., Bhagavathsingh, J. and Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517 (2023) Purification of PaTx-II from the venom of Australian King Brown Snake and characterization of its antimicrobial and wound healing activities. International Journal of Molecular Sciences, 24 (5). 4359. ISSN 1422-0067 doi: https://doi.org/10.3390/ijms24054359

Senthilkumaran, S., Almeida, J. R., Williams, J., Salim, A., Williams, H. F., Thirumalaikolundusubramanian, P., Patel, K. and Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517 (2023) Russell's viper envenomation induces rectus sheath haematoma. Toxicon, 224. 107037. ISSN 0041-0101 doi: https://doi.org/10.1016/j.toxicon.2023.107037

Senthilkumaran, S., Almeida, J. R., Williams, J., Williams, H. F., Thirumalaikolundusubramanian, P., Patel, K. and Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517 (2023) Rapid identification of bilateral adrenal and pituitary haemorrhages induced by Russell's viper envenomation results in positive patient outcome. Toxicon, 225. 107068. ISSN 0041-0101 doi: https://doi.org/10.1016/j.toxicon.2023.107068

Senthilkumaran, S., Arathisenthil, S. V., Williams, J., Almeida, J. R., Williams, H. F., Rajan, E., Thirumalaikolundusubramanian, P., Patel, K. and Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517 (2023) Neutrophil-mediated erythrophagocytosis following Russell's viper (Daboia russelii) bite. Toxicon, 228. 107111. ISSN 0041-0101 doi: https://doi.org/10.1016/j.toxicon.2023.107111

Senthilkumaran, S., Patel, K., Rajan, E., Vijayakumar, P., Miller, S. W., Rucavado, A., Gilabadi, S., Sonavane, M., Richards, N. J., Williams, J., Williams, H. F., Trim, S. A., Thirumalaikolundusubramanian, P., Gutiérrez, J. M. and Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517 (2023) Peripheral arterial thrombosis following Russell’s viper bites. TH Open, 07 (02). e168-e183. ISSN 2512-9465 doi: https://doi.org/10.1055/s-0043-1769625

Senthilkumaran, S., Salim, A., Almeida, J. R., Williams, J., Vijayakumar, P., Thirunavukarasu, A., Christopoulos, M. A., Williams, H. F., Thirumalaikolundusubramanian, P., Patel, K. and Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517 (2023) The effectiveness of antibiotics in managing bacterial infections on bite sites following snakebite envenomation. Toxins, 15 (3). 190. ISSN 2072-6651 doi: https://doi.org/10.3390/toxins15030190

Senthilkumaran, S., Sampath, S., Miller, S. W., Almeida, J. R., Williams, J., Williams, H. F., Thirumalaikolundusubramanian, P., Patel, K. and Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517 (2023) Partial segmental thrombosis of the corpus cavernosum following Russell’s viper bite. Toxicon, 234. 107284. ISSN 0041-0101 doi: https://doi.org/10.1016/j.toxicon.2023.107284

Skurikhin, E. G., Pershina, O. ORCID: https://orcid.org/0000-0002-0468-0272, Zhukova, M. ORCID: https://orcid.org/0000-0002-8146-2279, Pakhomova, A. ORCID: https://orcid.org/0000-0003-0725-1323, Ermakova, N., Widera, D. ORCID: https://orcid.org/0000-0003-1686-130X, Pan, E. ORCID: https://orcid.org/0000-0002-2163-7647, Sandrikina, L., Kogai, L., Kushlinskii, N., Morozov, S., Kubatiev, A. and Dygai, A. (2023) Reprogrammed CD8+ T-cells isolated from the mouse spleen increase the number of immune cells with antitumor activity and decrease the amount of cancer stem cells. Medical Science Forum, 21 (1). 40. ISSN 2673-9992 doi: https://doi.org/10.3390/ecb2023-14132

Sonavane, M., Almeida, J. R. ORCID: https://orcid.org/0000-0002-4637-4468, Rajan, E., Williams, H. F., Townsend, F., Cornish, E., Mitchell, R. D., Patel, K. and Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517 (2023) Intramuscular bleeding and formation of microthrombi during skeletal muscle damage caused by a snake venom metalloprotease and a cardiotoxin. Toxins, 15 (9). 530. ISSN 2072-6651 doi: https://doi.org/10.3390/toxins15090530

Stanford, S. C., Alexander, S., Cirino, G., George, C. H., Insel, P. A., Kendall, D., Ji, Y., Panettieri Jr., R. A., Patel, H. H., Sobey, C. G., Stefanska, B., Stephens, G. ORCID: https://orcid.org/0000-0002-8966-4238, Teixeira, M., Vergnolle, N., Ferdinandy, P. and Ahluwalia, A. (2023) Considering and reporting sex as an experimental variable II: an update on progress in the British Journal of Pharmacology. British Journal of Pharmacology, 180 (9). pp. 1191-1196. ISSN 1476-5381 doi: https://doi.org/10.1111/bph.16049

Stephens, G. J. ORCID: https://orcid.org/0000-0002-8966-4238 (2023) Cannabinoids. In: Gruol, D. L., Koibuchi, N., Manto, M., Molinari, M., Schmahmann, J. D. and Shen, Y. (eds.) Essentials of Cerebellum and Cerebellar Disorders. A Primer for Graduate Students. 2nd edition. Springer, pp. 221-224. ISBN 9783031150692 doi: https://doi.org/10.1007/978-3-031-15070-8_34

Stephens, G. J. ORCID: https://orcid.org/0000-0002-8966-4238 and Bell, D. C., (2023) 19th World Congress of Basic and Clinical Pharmacology, July 2nd–7th, 2023, Glasgow. Report. Mary Ann Liebert, Inc. doi: https://doi.org/10.1089/bioe.2023.0029

Sørensen, C. V., Almeida, J. R. ORCID: https://orcid.org/0000-0002-4637-4468, Bohn, M.-F., Torre, E. R. d., Schoffelen, S., Voldborg, B. G., Ljungars, A., Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517 and Laustsen, A. H. (2023) Discovery of a human monoclonal antibody that cross-neutralizes venom phospholipase A2s from three different snake genera. Toxicon, 234. 107307. ISSN 0041-0101 doi: https://doi.org/10.1016/j.toxicon.2023.107307

Toman, M., Wade, J. J., Verkhratsky, A., Dallas, M. ORCID: https://orcid.org/0000-0002-5190-0522, Bithell, A., Flanagan, B., Harkin, J. and McDaid, L. (2023) The influence of astrocytic leaflet motility on ionic signalling and homeostasis at active synapses. Scientific Reports, 13 (1). 3050. ISSN 2045-2322 doi: https://doi.org/10.1038/s41598-023-30189-8

Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517, Kadam, P., Chandrasekharuni, G., Oliveira, I. S., Senthilkumaran, S., Salim, A., Patel, K., Sachett, J. d. A. G. and Pucca, M. B. (2023) Multifaceted community health education programs as powerful tools to mitigate snakebite-induced deaths, disabilities, and socioeconomic burden. Toxicon: X, 17. 100147. ISSN 2590-1710 doi: https://doi.org/10.1016/j.toxcx.2022.100147

Williams, H. F., Moejes, K., Williams, J., Almeida, J. R. ORCID: https://orcid.org/0000-0002-4637-4468, Savania, R., Senthilkumaran, S., Patel, K. and Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517 (2023) Ashes to eye: a skilled snake handler’s experience with ophthalmic envenomation. PLoS Neglected Tropical Diseases, 17 (4). e0011264. ISSN 1935-2735 doi: https://doi.org/10.1371/journal.pntd.0011264

Williams, J. and Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517 (2023) The value of venom. Biologist, 70 (1). pp. 14-17. ISSN 0006-3347

Zharkova, O., Salamah, M. F., Babak, M. V., Rajan, E., Lim, L. H. K., Andrade, F., Gil, C. D., Oliani, S. M., Moraes, L. and Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517 (2023) Deletion of annexin A1 in mice upregulates the expression of its receptor, Fpr2/3, and reactivity to the AnxA1 mimetic peptide in platelets. International Journal of Molecular Sciences, 24 (4). 3424. ISSN 1422-0067 doi: https://doi.org/10.3390/ijms24043424

2022

Ablinger, C., Eibl, C., Geisler, S. M., Campiglio, M., Stephens, G. J. ORCID: https://orcid.org/0000-0002-8966-4238, Missler, M. and Obermair, G. J. (2022) α2δ-4 and Cachd1 proteins are regulators of presynaptic functions. International Journal of Molecular Sciences, 23 (17). 9885. ISSN 1422-0067 doi: https://doi.org/10.3390/ijms23179885

Albadawi, D. A. I., Ravishankar, D., Vallance, T. M., Patel, K., Osborn, H. M. I. ORCID: https://orcid.org/0000-0002-0683-0457 and Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517 (2022) Impacts of commonly used edible plants on the modulation of platelet function. International Journal of Molecular Sciences, 23 (2). 605. ISSN 1422-0067 doi: https://doi.org/10.3390/ijms23020605

Allman, S., Cordy, J., Hall, J. ORCID: https://orcid.org/0000-0003-3716-4378, Kleanthous, V. and Lander, L. (2022) Exploring the perception of additional information content in 360° 3D VR video for teaching and learning. Virtual Worlds, 1 (1). pp. 1-17. ISSN 2813-2084 doi: https://doi.org/10.3390/virtualworlds1010001

Alqallaf, A., Engelbeen, S., Palo, A., Cutrupi, F., Tanganyika-de Winter, C., Plomp, J., Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517, Aartsma-Rus, A., Patel, K. and Putten, M. v. (2022) The therapeutic potential of soluble activin type IIB receptor treatment in a limb girdle muscular dystrophy type 2D mouse model. Neuromuscular Disorders, 32 (5). pp. 419-435. ISSN 0960-8966 doi: https://doi.org/10.1016/j.nmd.2022.03.002

Arathisenthil, S. V., Senthilkumaran, S., Vijayakumar, P., Savania, R., Williams, H. F., Elangovan, N., Bicknell, A. B., Patel, K., Trim, S. A., Thirumalaikolundusubramanian, P. and Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517 (2022) Rapid development of a salivary calculus in submandibular gland and its potential causes in a young victim following Russell’s viper bite. Toxicon, 206. pp. 85-89. ISSN 0041-0101 doi: https://doi.org/10.1016/j.toxicon.2021.12.018

Banazadeh, M., Olangian-Tehrani, S., Sharifi, M., Malek- Ahmadi, M., Nikzad, F., Doozandeh- Nargesi, N., Mohammadi, A., Stephens, G. J. ORCID: https://orcid.org/0000-0002-8966-4238 and Shabani, M. (2022) Mechanisms of COVID-19-induced cerebellitis. Current medical research and opinion, 38 (12). pp. 2109-2118. ISSN 0300-799 doi: https://doi.org/10.1080/03007995.2022.2141963

Barberio, C., Saez, J., Withers, A., Nair, M., Tamagnini, F. ORCID: https://orcid.org/0000-0002-8741-5094 and Owens, R. M. (2022) Conducting polymer-ECM scaffolds for human neuronal cell differentiation. Advanced HEalthcare Materials, 11 (20). 2200941. ISSN 2192-2659 doi: https://doi.org/10.1002/adhm.202200941

Bell, D. C. and Dallas, M. L. ORCID: https://orcid.org/0000-0002-5190-0522 (2022) Advancing ion channel research with automated patch clamp (APC) electrophysiology platforms. In: Zhou, L. (ed.) Ion Channels in Biophysics and Physiology. Advances in Experimental Medicine and Biology, 1349. Springer, Singapore, pp. 21-32, VI, 413. ISBN 9789811642531 doi: https://doi.org/10.1007/978-981-16-4254-8_2

Bercea, C., Limbu, R., Behnam, K., Ng, K.-E., Aziz, Q., Tinker, A., Tamagnini, F. ORCID: https://orcid.org/0000-0002-8741-5094, Cottrell, G. S. ORCID: https://orcid.org/0000-0001-9098-7627 and McNeish, A. J. (2022) Omega-3 polyunsaturated fatty acid-induced vasodilation in mouse aorta and mesenteric arteries is not mediated by ATP-sensitive potassium channels. Frontiers in Physiology, 13. 1033216. ISSN 1664-042X doi: https://doi.org/10.3389/fphys.2022.1033216

Cogo, S. ORCID: https://orcid.org/0000-0002-5792-6897, Tomkins, J. E., Vavouraki, N., Giusti, V., Forcellato, F., Franchin, C., Tessari, I., Arrigoni, G., Cendron, L., Manzoni, C., Civiero, L., Lewis, P. A. and Greggio, E. (2022) Cytosolic sequestration of spatacsin by Protein Kinase A and 14-3-3 proteins. Neurobiology of Disease, 174. 105858. ISSN 1095-953x doi: https://doi.org/10.1016/j.nbd.2022.105858

Curtis, M. J., Alexander, S. P. H., Cirino, G., George, C. H., Kendall, D. A., Insel, P. A., Izzo, A. A., Ji, Y., Panettieri, R. A., Patel, H. H., Sobey, C. G., Stanford, S. C., Stanley, P., Stefanska, B., Stephens, G. ORCID: https://orcid.org/0000-0002-8966-4238, Teixeira, M. M., Vergnolle, N. and Ahluwalia, A. (2022) Planning experiments: updated guidance on experimental design and analysis and their reporting III. British Journal of Pharmacology, 179 (15). pp. 3907-3913. ISSN 0007-1188 doi: https://doi.org/10.1111/bph.15868

Diep, T. T. ORCID: https://orcid.org/0000-0001-7166-6369, Ray, P. P. ORCID: https://orcid.org/0000-0001-8375-8279 and Edwards, A. D. ORCID: https://orcid.org/0000-0003-2369-989X (2022) Methods for rapid prototyping novel labware: using CAD and desktop 3D printing in the microbiology laboratory. Letters in Applied Microbiology, 74 (2). pp. 247-257. ISSN 1472-765X doi: https://doi.org/10.1111/lam.13615

Gramignoli, R., Sallustio, F. and Widera, D. ORCID: https://orcid.org/0000-0003-1686-130X, eds. (2022) Tissue repair and regenerative mechanisms by stem/progenitor cells and their secretome, volume II. Frontiers in Medicine. Frontiers. doi: https://doi.org/10.3389/fmed.2022.901003

Haque, N., Widera, D. ORCID: https://orcid.org/0000-0003-1686-130X, Govindasamy, V., Soesilawati, P. and Kasim, N. H. A. (2022) Extracellular vesicles from stem and progenitor cells for cell-free regenerative therapy. Current Molecular Medicine, 22 (2). pp. 120-131. ISSN 1566-5240 doi: https://doi.org/10.2174/1566524021666210125114828

Hernández-Altamirano, J. A., Salazar-Valenzuela, D., Medina-Villamizar, E. J., Quirola, D. R., Patel, K., Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517, Lomonte, B. and Almeida, J. R. (2022) First insights into the venom composition of two Ecuadorian coral snakes. International Journal of Molecular Sciences, 23 (23). 14686. ISSN 1422-0067 doi: https://doi.org/10.3390/ijms232314686

Kaisis, E., Thei, L. J., Stephens, G. J. ORCID: https://orcid.org/0000-0002-8966-4238 and Dallas, M. L. ORCID: https://orcid.org/0000-0002-5190-0522 (2022) Protofibrillar amyloid beta modulation of recombinant hCaV2.2 (N-type) voltage-gated channels. Pharmaceuticals, 15 (12). 1459. ISSN 1424-8247 doi: https://doi.org/10.3390/ph15121459

Kanapeckaitė, A., Mažeikienė, A., Geris, L., Burokienė, N., Cottrell, G. S. ORCID: https://orcid.org/0000-0001-9098-7627 and Widera, D. ORCID: https://orcid.org/0000-0003-1686-130X (2022) Computational pharmacology: new avenues for COVID-19 therapeutics search and better preparedness for future pandemic crises. Biophysical Chemistry, 290. 106891. ISSN 0301-4622 doi: https://doi.org/10.1016/j.bpc.2022.106891

Kluss, J. H. ORCID: https://orcid.org/0000-0002-6262-6661, Lewis, P. A. ORCID: https://orcid.org/0000-0003-4537-0489 and Greggio, E. ORCID: https://orcid.org/0000-0002-8172-3598 (2022) Leucine-rich repeat kinase 2 (LRRK2): an update on the potential therapeutic target for Parkinson's disease. Expert Opinion on Therapeutic Targets, 26 (6). pp. 537-546. ISSN 1744-7631 doi: https://doi.org/10.1080/14728222.2022.2082937

MacMillan, S., Holmes, A. P., Dallas, M. L. ORCID: https://orcid.org/0000-0002-5190-0522, Mahmoud, A. D., Shipston, M. J., Peers, C., Hardie, D. G., Kumar, P. and Evans, A. M. (2022) LKB1 is the gatekeeper of carotid body chemosensing and the hypoxic ventilatory response. Communications Biology, 5. 642. ISSN 2399-3642 doi: https://doi.org/10.1038/s42003-022-03583-7

Mydin, R. S. M. N., Sreekantan, S., Widera, D. ORCID: https://orcid.org/0000-0003-1686-130X, Saharudin, K. A., Hazan, R. and Wajidi, M. F. F. (2022) Genome-nanosurface interaction of Titania Nanotube Arrays: evaluation of telomere, telomerase and NF-κB activities on epithelial cell model. RSC Advances, 12 (4). pp. 2237-2245. ISSN 2046-2069 doi: https://doi.org/10.1039/D1RA05325F

Natarajan, N., Ramprasath, T., Gopas, J., Subbiah, R., Rajendran, P. and Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517, eds. (2022) Development of novel small molecules as therapeutics for inflammatory diseases and delineating their molecular mechanisms. Frontiers in Pharmacology (Special Issue), 13. Frontiers.

Needs, S. H. ORCID: https://orcid.org/0000-0003-3407-9637, Bootman, M. D., Grotzke, J. E., Kramer, H. B. and Allman, S. A. (2022) Off-target inhibition of NGLY1 by the poly-caspase inhibitor Z-VAD-fmk induces cellular autophagy. The FEBS Journal, 289 (11). pp. 3115-3131. ISSN 1742-464X doi: https://doi.org/10.1111/febs.16345

Senthilkumaran, S., Arathisenthil, S. V., Williams, J., Williams, H. F., Thirumalaikolundusubramanian, P., Patel, K. and Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517 (2022) An unnecessary Russell’s Viper bite on the tongue due to live snake worship and dangerous first aid emphasise the urgent need for stringent policies. Toxins, 14 (12). 817. ISSN 2072-6651 doi: https://doi.org/10.3390/toxins14120817

Senthilkumaran, S., Miller, S. W., Williams, H. F., Savania, R., Thirumalaikolundusubramanian, P., Patel, K. and Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517 (2022) Development of Wunderlich Syndrome following a Russell’s viper bite. Toxicon, 215. pp. 11-16. ISSN 0041-0101 doi: https://doi.org/10.1016/j.toxicon.2022.06.004

Senthilkumaran, S., Miller, S. W., Williams, H. F., Thirumalaikolundusubramanian, P., Patel, K. and Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517 (2022) Bilateral simultaneous optic neuritis following envenomations by Indian cobra and common krait. Toxins, 14 (11). 805. ISSN 2072-6651 doi: https://doi.org/10.3390/toxins14110805

Senthilkumaran, S., Miller, S. W., Williams, H. F., Thirumalaikolundusubramanian, P., Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517 and Patel, K. (2022) Hirata’s disease (insulin autoimmune syndrome) following envenomation by a common krait. Toxicon, 219. 106923. ISSN 0041-0101 doi: https://doi.org/10.1016/j.toxicon.2022.09.009

Senthilkumaran, S., Miller, S. W., Williams, H. F., Vaiyapuri, R., Savania, R., Elangovan, N., Thirumalaikolundusubramanian, P., Patel, K. and Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517 (2022) Ultrasound-guided compression method effectively counteracts Russell’s viper bite-induced pseudoaneurysm. Toxins, 14 (4). 260. ISSN 2072-6651 doi: https://doi.org/10.3390/toxins14040260

Skurikhin, E. G., Ermakova, N., Zhukova, M. ORCID: https://orcid.org/0000-0002-8146-2279, Pershina, O. ORCID: https://orcid.org/0000-0002-0468-0272, Pan, E. ORCID: https://orcid.org/0000-0002-2163-7647, Pakhomova, A. ORCID: https://orcid.org/0000-0003-0725-1323, Kogai, L., Goldberg, V., Simolina, E., Skurikhina, V., Widera, D. ORCID: https://orcid.org/0000-0003-1686-130X, Kubatiev, A., Morozov, S. G., Kushlinskii, N. and Dygai, A. (2022) Analysis of circulating tumor and cancer stem cells provides new opportunities in diagnosis and treatment of small cell lung cancer. International Journal of Molecular Sciences, 23 (18). 10853. ISSN 1422-0067 doi: https://doi.org/10.3390/ijms231810853

Skurikhin, E. G., Ermakova, N., Zhukova, M., Pershina, O., Pan, E., Pakhomova, A., Kogai, L., Goldberg, V., Simolina, E., Skurikhina, V., Widera, D. ORCID: https://orcid.org/0000-0003-1686-130X, Kubatiev, A., Morozov, S. G., Kushlinskii, N. and Dygai, A. (2022) Analysis of circulating tumour and cancer stem cells provides new opportunities in diagnosis and treatment of small cell lung cancer. International Journal of Molecular Sciences, 23 (18). 10853. ISSN 1422-0067 doi: https://doi.org/10.3390/ijms231810853

Skurikhin, E. G., Pershina, O., Ermakova, N., Pakhomova, A., Zhukova, M., Pan, E., Sandrikina, L., Widera, D. ORCID: https://orcid.org/0000-0003-1686-130X, Kogai, L., Kushlinskii, N., Kubatiev, A., Morozov, S. and Dygai, A. (2022) Cell therapy with human reprogrammed CD8+ T-cells has antimetastatic effects on Lewis Lung Carcinoma in C57BL/6 mice. International Journal of Molecular Sciences, 23 (24). 15780. ISSN 1422-0067 doi: https://doi.org/10.3390/ijms232415780

Stephens, G. J. ORCID: https://orcid.org/0000-0002-8966-4238 and Shukla, A. K. (2022) Targeting the cell's gatekeepers for novel drug discovery. British Journal of Pharmacology, 179 (14). pp. 3485-3486. ISSN 0007-1188 doi: https://doi.org/10.1111/bph.15831

2021

Alatawi, K., Ravishankar, D., Patra, P., Bye, A. ORCID: https://orcid.org/0000-0002-2061-2253, Stainer, A., Patel, K., Widera, D. ORCID: https://orcid.org/0000-0003-1686-130X and Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517 (2021) 1,8-cineole affects agonists-induced platelet activation, thrombus formation and haemostasis. Cells, 10 (10). 2616. ISSN 2073-4409 doi: https://doi.org/10.3390/cells10102616

Bercea, C.-I., Cottrell, G. S. ORCID: https://orcid.org/0000-0001-9098-7627, Tamagnini, F. ORCID: https://orcid.org/0000-0002-8741-5094 and McNeish, A. J. (2021) Omega-3 polyunsaturated fatty acids (ω-3 PUFAs) and hypertension: a review of vasodilatory mechanisms of DHA and EPA. British Journal of Pharmacology, 178 (4). pp. 860-877. ISSN 0007-1188 doi: https://doi.org/10.1111/bph.15336

Bicer, M. (2021) Developing a novel 3D platform for investigating the osteogenic differentiation and the anti-inflammatory potential of human mesenchymal stem cells and their secretome. PhD thesis, University of Reading. doi: https://doi.org/10.48683/1926.00106616

Bicer, M., Cottrell, G. S. ORCID: https://orcid.org/0000-0001-9098-7627 and Widera, D. ORCID: https://orcid.org/0000-0003-1686-130X (2021) Impact of 3D cell culture on bone regeneration potential of mesenchymal stromal cells. Stem cell research and therapy, 12. 31. ISSN 1757-6512 doi: https://doi.org/10.1186/s13287-020-02094-8

Dallas, M. ORCID: https://orcid.org/0000-0002-5190-0522 and Widera, D. ORCID: https://orcid.org/0000-0003-1686-130X (2021) TLR2 and TLR4-mediated inflammation in Alzheimer`s disease: self-defense or sabotage? Neural Regeneration Research, 16 (8). pp. 1552-1553. ISSN 1876-7958 doi: https://doi.org/10.4103/1673-5374.303016

Dallas, M. L. ORCID: https://orcid.org/0000-0002-5190-0522, Al-Owais, M. M., Hettiarachchi, N. T., Vandiver, M. S., Jarosz-Griffiths, H. H., Scragg, J. L., Boyle, J. P., Dallas, D. and Peers, C. (2021) Hydrogen sulfide regulates hippocampal neuron excitability via S-sulfhydration of Kv2.1. Scientific Reports, 11. 8194. ISSN 2045-2322 doi: https://doi.org/10.1038/s41598-021-87646-5

George, C. H., Alexander, S. P. H., Cirino, G., Insel, P. A., Izzo, A. A., JI, Y., Kendall, D. A., Panettieri, R. A., Patel, H. H., Sobey, C. G., Stanford, S. C., Stefanska, B., Stephens, G. ORCID: https://orcid.org/0000-0002-8966-4238, Teixeira, M. and Ahluwalia, A. (2021) Editorial policy regarding the citation of preprints in the British Journal of Pharmacology (BJP). British Journal of Pharmacology, 178 (18). pp. 3605-3610. ISSN 0007-1188 doi: https://doi.org/10.1111/bph.15589

Kanapeckaitė, A., Burokienė, N., Mažeikienė, A., Cottrell, G. S. ORCID: https://orcid.org/0000-0001-9098-7627 and Widera, D. ORCID: https://orcid.org/0000-0003-1686-130X (2021) Biophysics is reshaping our perception of the epigenome: from changing the landscape of how we study DNA-level epigenetic marks to enabling high-throughput applications. Biophysical Reports, 1 (2). 100028. ISSN 2667-0747 doi: https://doi.org/10.1016/j.bpr.2021.100028

Majeed, K. R., Al-Fahad, D., Jalood, H. H., Hantosh, H. A., Ali, M. K., Sakthivel, S., Williams, H. F., Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352, Patel, K., Baksh, M. F. ORCID: https://orcid.org/0000-0003-3107-8815 and Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517 (2021) RhD blood type significantly influences susceptibility to contract COVID-19 among a study population in Iraq. F1000Research. ISSN 2046-1402 doi: https://doi.org/10.12688/f1000research.27777.1

Pershina, O., Ermakova, N., Pakhomova, A., Widera, D. ORCID: https://orcid.org/0000-0003-1686-130X, Pan, E., Zhukova, M., Slonimskaya, E., Morozov, S. G., Kubatiev, A., Dygai, A. and Skurikhin, E. G. (2021) Cancer stem cells and somatic stem cells as potential new drug targets, prognosis markers, and therapy efficacy predictors in breast cancer treatment. Biomedicines, 9 (9). 1223. ISSN 2227-9059 doi: https://doi.org/10.3390/biomedicines9091223

Poshtkohi, A. ORCID: https://orcid.org/0000-0001-5636-1567, Wade, J. ORCID: https://orcid.org/0000-0003-1300-9429, McDaid, L. ORCID: https://orcid.org/0000-0002-1197-4375, Liu, J. ORCID: https://orcid.org/0000-0002-9790-1571, Dallas, M. ORCID: https://orcid.org/0000-0002-5190-0522 and Bithell, A. ORCID: https://orcid.org/0000-0002-0294-078X (2021) Mathematical modelling of human P2X-mediated plasma membrane electrophysiology and calcium dynamics in microglia. PLOS Computational Biology, 17 (11). e1009520. ISSN 1553-7358 doi: https://doi.org/10.1371/journal.pcbi.1009520

Ridzuan, N., Zakaria, N., Widera, D. ORCID: https://orcid.org/0000-0003-1686-130X, Sheard, J., Morimoto, M., Kiyokawa, H., Azmel Mohd Isa, S., Singh, G. K. C., Then, K.-Y., Ooi, G.-C. and Yahaya, B. H. (2021) Human umbilical cord mesenchymal stem cell-derived extracellular vesicles ameliorate airway inflammation in a rat model of Chronic Obstructive Pulmonary Disease (COPD). Stem cell research and therapy, 12 (1). 54. ISSN 1757-6512 doi: https://doi.org/10.1186/s13287-020-02088-6

Roosterman, D. and Cottrell, G. S. ORCID: https://orcid.org/0000-0001-9098-7627 (2021) The two-cell model of glucose metabolism: a hypothesis of schizophrenia. Molecular Psychiatry, 26. pp. 1738-1747. ISSN 1476-5578 doi: https://doi.org/10.1038/s41380-020-00980-4

Sahli, K. A., Flora, G. D., Sasikumar, P., Maghrabi, A. H., Holbrook, L., AlOuda, S. K., Elgheznawy, A., Sage, T., Stainer, A. R., Adiyaman, R., AboHassan, M., Crescente, M., Kriek, N., Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517, Bye, A. P. ORCID: https://orcid.org/0000-0002-2061-2253, Unsworth, A. J., Jones, C. I. ORCID: https://orcid.org/0000-0001-7537-1509, McGuffin, L. J. ORCID: https://orcid.org/0000-0003-4501-4767 and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 (2021) Structural, functional and mechanistic insights uncover the fundamental role of orphan connexin-62 in platelets. Blood, 137 (6). pp. 830-843. ISSN 0006-4971 doi: https://doi.org/10.1182/blood.2019004575

Senthilkumaran, S., Patel, K., Salim, A., Vijayakumar, P., Williams, H. F., Vaiyapuri, R., Savania, R., Elangovan, N., Thirumalaikolundusubramanian, P., Baksh, M. F. ORCID: https://orcid.org/0000-0003-3107-8815 and Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517 (2021) Neutrophil gelatinase-associated lipocalin acts as a robust early diagnostic marker for renal replacement therapy in patients with Russell’s viper bite-induced acute kidney injuries. Toxins, 13 (11). 797. ISSN 2072-6651 doi: https://doi.org/10.3390/toxins13110797

Senthilkumaran, S., Vijayakumar, P., Savania, R., Vaiyapuri, R., Elangovan, N., Patel, K., Trim, S. A., Thirumalaikolundusubramanian, P. and Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517 (2021) Splenic rupture and subsequent splenectomy in a young healthy victim following Russell’s viper bite. Toxicon, 204. pp. 9-13. ISSN 0041-0101 doi: https://doi.org/10.1016/j.toxicon.2021.10.010

Senthilkumaran, S., Williams, H. F., Patel, K., Trim, S. A., Thirumalaikolundusubramanian, P. and Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517 (2021) Priapism following a juvenile Russell’s viper bite: an unusual case report. PLoS Neglected Tropical Diseases, 15 (3). ISSN 1935-2735 doi: https://doi.org/10.1371/journal.pntd.0009242

Silveirinha, V., Lin, H., Tanifuji, S., Mochida, S., Cottrell, G. ORCID: https://orcid.org/0000-0001-9098-7627, Cimarosti, H. and Stephens, G. ORCID: https://orcid.org/0000-0002-8966-4238 (2021) CaV2.2 (N-type) voltage-gated calcium channels are activated by SUMOylation pathways. Cell Calcium, 93. 102326. ISSN 0143-4160 doi: https://doi.org/10.1016/j.ceca.2020.102326

Skurikhin, E., Madonov, P., Pershina, O., Ermakova, N., Pakhomova, A., Widera, D. ORCID: https://orcid.org/0000-0003-1686-130X, Pan, E., Zhukova, M., Sandrikina, L., Artamonov, A. and Dygai, A. (2021) Micellar Hyaluronidase and Spiperone as a potential treatment for pulmonary fibrosis. International Journal of Molecular Sciences, 22 (11). 5599. ISSN 1422-0067 doi: https://doi.org/10.3390/ijms22115599

Skurikhin, E., Pershina, O., Zhukova, M., Widera, D. ORCID: https://orcid.org/0000-0003-1686-130X, Ermakova, N., Pan, E., Pakhomova, A. V., Morozov, S., Kubatiev, A. and Dygai, A. (2021) Potential of stem cells and CART as a potential polytherapy for small cell lung cancer. Frontiers in Cell and Developmental Biology, 9. 778020. ISSN 2296-634X doi: https://doi.org/10.3389/fcell.2021.778020

Skurikhin, E., Pershina, O., Zhukova, M., Widera, D. ORCID: https://orcid.org/0000-0003-1686-130X, Pan, E., Pakhomova, A., Krupin, V., Ermakova, N., Skurikhina, V., Sandrikina, L., Morozov, S., Kubatiev, A. and Dygai, A. (2021) Spiperone stimulates regeneration in pulmonary endothelium damaged by cigarette smoke and lipopolysaccharide. International Journal of Chronic Obstructive Pulmonary Disease, 16. pp. 3575-3591. ISSN 1178-2005 doi: https://doi.org/10.2147/COPD.S336410

Torre, E. V., Bicer, M., Cottrell, G. ORCID: https://orcid.org/0000-0001-9098-7627, Widera, D. ORCID: https://orcid.org/0000-0003-1686-130X and Tamagnini, F. ORCID: https://orcid.org/0000-0002-8741-5094 (2021) Time-dependent reduction of calcium oscillations in adipose-derived stem cells differentiating towards adipogenic and osteogenic lineage. Biomolecules, 11 (10). 1400. ISSN 2218-273X doi: https://doi.org/10.3390/biom11101400

Vallance, T., Sheard, J., Meng, Y., Torre, E., Patel, K., Widera, D. ORCID: https://orcid.org/0000-0003-1686-130X and Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517 (2021) Development and characterisation of a novel, megakaryocyte NF-κB reporter cell line for investigating inflammatory responses. Journal of Thrombosis and Haemostasis, 19 (1). pp. 107-120. ISSN 1538-7933 doi: https://doi.org/10.1111/jth.15118

Vaughan, D., Mitchell, R., Kretz, O., Chambers, D., Lalowski, M., Amthor, H., Ritvos, O., Pasternack, A., Matsakas, A., Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517, Huber, T. B., Denecke, B., Mukherjee, A., Widera, D. ORCID: https://orcid.org/0000-0003-1686-130X and Patel, K. (2021) A muscle growth promoting treatment based on the attenuation of activin/myostatin signalling in young mice results in long-term testicular abnormalities. Disease Models & Mechanisms, 14 (2). ISSN 1754-8411 doi: https://doi.org/10.1242/dmm.047555

Vavouraki, N. ORCID: https://orcid.org/0000-0003-2581-4935, Tomkins, J. E. ORCID: https://orcid.org/0000-0003-3010-6634, Kara, E. ORCID: https://orcid.org/0000-0001-5428-6743, Houlden, H., Hardy, J., Tindall, M. J., Lewis, P. A. ORCID: https://orcid.org/0000-0003-4537-0489 and Manzoni, C. (2021) Integrating protein networks and machine learning for disease stratification in the Hereditary Spastic Paraplegias. iScience, 24 (5). 102484. ISSN 2589-0042 doi: https://doi.org/10.1016/j.isci.2021.102484

Widera, D. ORCID: https://orcid.org/0000-0003-1686-130X, Ong, W. K. and Sheard, J., eds. (2021) Recent advances in Translational Adipose-Derived Stem Cell Biology. MDPI, Biomolecules. doi: https://doi.org/10.3390/biom11111660

2020

Bianchi, R., Eilers, W., Pellati, F., Corsi, L., Foster, H., Foster, K. and Tamagnini, F. ORCID: https://orcid.org/0000-0002-8741-5094 (2020) Hippocampal synaptic and membrane function in the DBA/2J-mdx mouse model of Duchenne muscular dystrophy. Molecular and Cellular Neuroscience, 104. 103482. ISSN 1044-7431 doi: https://doi.org/10.1016/j.mcn.2020.103482

Bicer, M., Sheard, J., Iandolo, D., Boateng, S. Y., Cottrell, G. S. ORCID: https://orcid.org/0000-0001-9098-7627 and Widera, D. ORCID: https://orcid.org/0000-0003-1686-130X (2020) Electrical stimulation of adipose-derived stem cells in 3D nanofibrillar cellulose increases their osteogenic potential. Biomolecules, 10 (12). ISSN 2218-273X doi: https://doi.org/10.3390/biom10121696

The University of Newcastle Upon Tyne , Newcastle upon Tyne ( GB (2020) Transport of cells in hydrogels. US 10,655,120 B2. doi: US 10,655,120 B2

Crescente, M., Armstrong, P. C., Kirkby, N. S., Edin, M. L., Chan, M. V., Lih, F. B., Jiao, J., Maffucci, T., Allan, H. E., Mein, C. A., Gaston-Massuet, C., Cottrell, G. S. ORCID: https://orcid.org/0000-0001-9098-7627, Mitchell, J. A., Zeldin, D. C., Herschman, H. R. and Warner, T. D. (2020) Profiling the eicosanoid networks that underlie the anti- and pro-thrombotic effects of aspirin. FASEB Journal, 34 (8). pp. 10027-10040. ISSN 0892-6638 doi: https://doi.org/10.1096/fj.202000312R

Ebanks, K., Lewis, P. A. and Bandopadhyay, R. (2020) Vesicular dysfunction and the pathogenesis of Parkinson's disease: clues from genetic studies. Frontiers in Neuroscience, 13. 1381. ISSN 1662-453X doi: https://doi.org/10.3389/fnins.2019.01381

Iandolo, D., Sheard, J., Katarivas Levy, G., Pitsalidis, C., Tan, E., Dennis, A., Kim, J.-S., Markaki, A., Widera, D. ORCID: https://orcid.org/0000-0003-1686-130X and Owens, R. (2020) Biomimetic and electroactive 3D scaffolds for human neural crest-derived stem cell expansion and osteogenic differentiation. MRS Communications, 10 (1). pp. 179-187. ISSN 2159-6859 doi: https://doi.org/10.1557/mrc.2020.10

Izzo, A. A., Teixeira, M., Alexander, S. P.H., Cirino, G., Docherty, J. R., George, C. H., Insel, P. A., Ji, Y., Kendall, D. A., Panattieri, R. A., Sobey, C. G., Stanford, S. C., Stefanska, B., Stephens, G. ORCID: https://orcid.org/0000-0002-8966-4238 and Ahluwalia, A. (2020) A practical guide for transparent reporting of research on natural products in the British Journal of Pharmacology: reproducibility of natural product research. British Journal of Pharmacology, 177 (10). pp. 2169-2178. ISSN 0007-1188 doi: https://doi.org/10.1111/bph.15054

Karathanasis, C., Medler, J., Fricke, F., Smith, S., Malkusch, S., Widera, D. ORCID: https://orcid.org/0000-0003-1686-130X, Fulda, S., Wajant, H., van Wijk, S. J. L., Dikic, I. and Heilemann, M. (2020) Single-molecule imaging reveals the oligomeric state of functional TNFα-induced plasma membrane TNFR1 clusters in cells. Science Signaling, 13 (614). eaax5647. ISSN 1937-9145 doi: https://doi.org/10.1126/scisignal.aax5647

Knudsen, C., Casewell, N., Lomonte, B., Gutiérrez, J. M., Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517 and Laustsen, A. (2020) Novel snakebite therapeutics must be tested in appropriate rescue models to robustly assess their preclinical efficacy. Toxins, 12 (9). 528. ISSN 2072-6651 doi: https://doi.org/10.3390/toxins12090528

Layfield, H. J., Williams, H. F., Ravishankar, D., Mehmi, A., Sonavane, M., Salim, A., Vaiyapuri, R., Lakshminarayanan, K., Vallance, T. M., Bicknell, A. B., Trim, S. A., Patel, K. and Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517 (2020) Repurposing cancer drugs, batimastat and marimastat, to inhibit the activity of a group I metalloprotease from the venom of the Western Diamondback rattlesnake, Crotalus atrox. Toxins, 12 (5). 309. ISSN 2072-6651 doi: https://doi.org/10.3390/toxins12050309

Lilley, E., Stanford, S. C., Kendall, D. E., Alexander, S. P. H., Cirino, G., Docherty, J. R., George, C. H., Insel, P. A., Izzo, A. A., Ji, Y., Panettieri, R. A., Sobey, C. G., Stefanska, B., Stephens, G. ORCID: https://orcid.org/0000-0002-8966-4238, Teixeira, M. and Ahluwalia, A. (2020) ARRIVE 2.0 and the British Journal of Pharmacology: updated guidance for 2020. British Journal of Pharmacology, 177 (16). pp. 3611-3616. ISSN 0007-1188 doi: https://doi.org/10.1111/bph.15178

Miller, S. W., Osterhoudt, K. C., Korenoski, A. S., Patel, K. and Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517 (2020) Exotic snakebites reported to Pennsylvania poison control centers: lessons learned on the demographics, clinical effects, and treatment of these cases. Toxins, 12 (12). 755. ISSN 2072-6651 doi: https://doi.org/10.3390/toxins12120755

Pakhomova, A., Pershina, O., Vladimir, N., Natalia, E., Vyacheslav, K., Lubov, S., Edgar, P., Widera, D. ORCID: https://orcid.org/0000-0003-1686-130X, Alexander, D. and Evgenii, S. (2020) Bisamide derivative of Dicarboxylic Acid contributes to restoration of testicular tissue function and influences spermatogonial stem cells in metabolic disorders. Frontiers in Cell and Developmental Biology, 8. 562358. ISSN 2296-634X doi: https://doi.org/10.3389/fcell.2020.562358

Pakhomova, V. P., Nebolsin, V. E., Pershina, O. V., Krupin, V. A., Sandrikina, L. A., Pan, E. S., Ermakova, N. N., Vaizova, O. E., Widera, D. ORCID: https://orcid.org/0000-0003-1686-130X, Grimm, W.-D., Kravtsov, V. Y.’e., Afanasiev, S. A., Morozov, S. G., Kubatiev, A. A., Dygai, A. M. and Skurikhin, E. G. (2020) Antidiabetic effects of Bisamide Derivative of Dicarboxylic Acid in metabolic disorders. International Journal of Molecular Sciences, 21 (3). 991. ISSN 1422-0067 doi: https://doi.org/10.3390/ijms21030991

Patra, P. H., Serafeimidou-Pouliou, E., Bazelot, M., Whalley, B. J., Williams, C. M. ORCID: https://orcid.org/0000-0003-4452-671X and McNeish, A. J. (2020) Cannabidiol (CBD) improves survival and behavioural comorbidities of Dravet syndrome in mice. British Journal of Pharmacology, 177 (12). pp. 2779-2792. ISSN 0007-1188 doi: https://doi.org/10.1111/bph.15003

Perry, C. J., Finch, P., Muller-Taubenberger, A., Leung, K.-Y., Warren, E. C., Damstra-Oddy, J., Sharma, D., Patra, P. H., Glyn, S., Boberska, J., Stewart, B., Baldwin, A., Piscitelli, F., Harvey, R. J., Harwood, A., Thompson, C., Claus, S. P., Greene, N. D. E., McNeish, A. J., Williams, C. M. ORCID: https://orcid.org/0000-0003-4452-671X, Whalley, B. J. and Williams, R. S. B. (2020) A new mechanism for Cannabidiol in regulating the one-carbon cycle and methionine levels in Dictyostelium and in mammalian epilepsy models. British Journal of Pharmacology, 177 (4). pp. 912-928. ISSN 0007-1188 doi: https://doi.org/10.1111/bph.14892

Rawlinson, C., Jenkins, S., Thei, L., Dallas, M. L. ORCID: https://orcid.org/0000-0002-5190-0522 and Chen, R. (2020) Post-ischaemic immunological response in the brain: targeting microglia in ischaemic stroke therapy. Brain Sciences, 10 (3). 159. ISSN 2076-3425 doi: https://doi.org/10.3390/brainsci10030159

Roosterman, D. and Cottrell, G. S. ORCID: https://orcid.org/0000-0001-9098-7627 (2020) Astrocytes and neurons communicate via a monocarboxylic acid shuttle. AIMS Neuroscience, 7 (2). pp. 94-106. ISSN 2373-7972 doi: https://doi.org/10.3934/Neuroscience.2020007

Salamah, M., Vallance, T., Kodji, X., Ravishankar, D., Williams, H., Brain, S. and Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517 (2020) The antimicrobial cathelicidin CRAMP augments platelet activation during psoriasis in mice. Biomolecules, 10 (9). 1267. ISSN 2218-273X doi: https://doi.org/10.3390/biom10091267

Samuel, S. P., Chinnaraju, S., Williams, H., Pichamuthu, E., Subharao, M., Vaiyapuri, M., Arumugam, S., Vaiyapuri, R., Baksh, F. ORCID: https://orcid.org/0000-0003-3107-8815, Patel, K., Trim, S., Duncombe, T. ORCID: https://orcid.org/0000-0003-4746-4470 and Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517 (2020) Venomous snakebites: rapid action saves lives - a multifaceted community education programme increases awareness about snakes and snakebites among the rural population of Tamil Nadu, India. PLoS Neglected Tropical Diseases, 14 (12). e0008911. ISSN 1935-2735 doi: https://doi.org/10.1371/journal.pntd.0008911

Skurikhin, E., Nebolsin, V., Widera, D. ORCID: https://orcid.org/0000-0003-1686-130X, Ermakova, N., Pershina, O., Pakhomova, A., Krupin, V., Pan, E., Zhukova, M., Novikov, F., Sandrikina, L., Morozov, S., Kubatiev, A. and Dygai, A. (2020) Antifibrotic and regenerative effects of Treamid in pulmonary fibrosis. International Journal of Molecular Sciences, 21 (21). 8380. ISSN 1422-0067 doi: https://doi.org/10.3390/ijms21218380

Tait, L., Tamagnini, F. ORCID: https://orcid.org/0000-0002-8741-5094, Stothart, G., Barvas, E., Monaldini, C., Frusciante, R., Volpini, M., Guttmann, S., Coulthard, E., Brown, J., Kazanina, N. and Goodfellow, M. (2020) EEG microstate complexity for aiding early diagnosis of Alzheimer’s disease. Scientific Reports, 10. 17627. ISSN 2045-2322 doi: https://doi.org/10.1038/s41598-020-74790-7

Tamagnini, F. ORCID: https://orcid.org/0000-0002-8741-5094 (2020) Nucleated, outside-out, somatic, macropatch recordings in native neurons. In: Mark, D. and Damian, B. (eds.) Patch Clamp Electrophysiology Methods and Protocols. Humana, New York, NY, pp. 229-242. ISBN 9781071608173 doi: https://doi.org/10.1007/978-1-0716-0818-0_11

Trim, S. A., Trim, C. M., Williams, H. F. and Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517 (2020) The failures of ethnobotany and phytomedicine in delivering novel treatments for snakebite envenomation. Toxins, 12 (12). 774. ISSN 2072-6651 doi: https://doi.org/10.3390/toxins12120774

Vaughan, D., Ritvos, O., Mitchell, R., Kretz, O., Lalowski, M., Amthor, H., Chambers, D., Matsakas, A., Pasternack, A., Collins-Hooper, H., Ballesteros, R., Huber, T. B., Denecke, B., Widera, D. ORCID: https://orcid.org/0000-0003-1686-130X, Mukherjee, A. and Patel, K. (2020) Inhibition of Activin/Myostatin signalling induces skeletal muscle hypertrophy but impairs mouse testicular development. European journal of translational myology, 30 (1). pp. 62-78. ISSN 2037-7452 doi: https://doi.org/10.4081/ejtm.2019.8737

Williams, C. ORCID: https://orcid.org/0000-0003-4452-671X and Stephens, G. ORCID: https://orcid.org/0000-0002-8966-4238 (2020) Development of cannabidiol as a treatment for severe childhood epilepsies. British Journal of Pharmacology, 177 (24). pp. 5509-5517. ISSN 0007-1188 doi: https://doi.org/10.1111/bph.15274

Ziegler, K., Kunert, A., Reinmuth-Selzle, K., Leifke, A. L., Widera, D. ORCID: https://orcid.org/0000-0003-1686-130X, Weller, M., Schuppan, D., Fröhlich-Nowoisky, J., Lucas, K. and Pöschl, U. (2020) Chemical modification of pro-inflammatory proteins by peroxynitrite increases activation of TLR4 and NF-κB: implications for the health effects of air pollution and oxidative stress. Redox Biology, 37. 101581. ISSN 2213-2317 doi: https://doi.org/10.1016/j.redox.2020.101581

2019

Brierley, D. I., Harman, J. R., Giallourou, N., Leishman, E., Roashan, A. E., Mellows, B. A. D., Bradshaw, H. B., Swann, J. R., Patel, K., Whalley, B. J. and Williams, C. M. ORCID: https://orcid.org/0000-0003-4452-671X (2019) Chemotherapy-induced cachexia dysregulates hypothalamic and systemic lipoamines and is attenuated by cannabigerol. Journal of Cachexia, Sarcopenia and Muscle, 10 (4). pp. 844-859. ISSN 2190-6009 doi: https://doi.org/10.1002/jcsm.12426

Brown, P., RELISH Consortium, , Zhou, Y. and Widera, D. ORCID: https://orcid.org/0000-0003-1686-130X (2019) Large expert-curated database for benchmarking document similarity detection in biomedical literature search. Database, 2019. baz085. ISSN 1758-0463 doi: https://doi.org/10.1093/database/baz085

De Simone, A., Naldi, M., Tedesco, D., Milelli, A., Bartolini, M., Davani, L., Widera, D. ORCID: https://orcid.org/0000-0003-1686-130X, Dallas, M. ORCID: https://orcid.org/0000-0002-5190-0522 and Andrisano, V. (2019) Investigating in vitro amyloid peptide 1-42 aggregation: impact of higher molecular weight stable adducts. ACS Omega, 4 (7). pp. 12308-12318. ISSN 2470-1343 doi: https://doi.org/10.1021/acsomega.9b01531

Docherty, J. R., Stanford, S. C., Panattieri, R. A., Alexander, S. P.H., Cirino, G., George, C. H., Hoyer, D., Izzo, A. A., Ji, Y., Lilley, E., Sobey, C. G., Stanley, P., Stefanska, B., Stephens, G. ORCID: https://orcid.org/0000-0002-8966-4238, Teixeira, M. and Ahluwalia, A. (2019) Sex: a change in our guidelines to authors to ensure that this is no longer an ignored experimental variable. British Journal of Pharmacology, 176 (21). pp. 4081-4086. ISSN 0007-1188 doi: https://doi.org/10.1111/bph.14761

Gramignoli, R., Sallustio, F., Widera, D. ORCID: https://orcid.org/0000-0003-1686-130X and Raschzok, N., eds. (2019) Tissue repair and regenerative mechanisms by stem/progenitor cells and their secretome. Frontiers in Medicine. Frontiers.

Haque, N., Widera, D. ORCID: https://orcid.org/0000-0003-1686-130X and Abu Kasim, N. H. (2019) Stem cells from human extracted deciduous teeth expanded in foetal bovine and human sera express different paracrine factors after exposure to freshly prepared human serum. Advances in Experimental Medicine and Biology. pp. 175-186. ISSN 0065-2598 doi: https://doi.org/10.1007/5584_2018_299

Karampatakis, G. D., Ryan, K., Patel, N. ORCID: https://orcid.org/0000-0002-8600-0663 and Stretch, G. (2019) Capturing pharmacists' impact in general practice: an e-Delphi study to attempt to reach consensus amongst experts about what activities to record. BMC Family Practice, 20 (1). 126. ISSN 1471-2296 doi: https://doi.org/10.1186/s12875-019-1008-6

Karampatakis, G. D., Ryan, K., Patel, N. ORCID: https://orcid.org/0000-0002-8600-0663, Lau, W. M. and Stretch, G. (2019) How do pharmacists in English general practices identify their impact? An exploratory qualitative study of measurement problems. BMC Health Services Research, 19 (34). ISSN 1472-6963 doi: https://doi.org/10.1186/s12913-018-3842-y

Lewis, P. A. (2019) Leucine Rich Repeat Kinase 2: a paradigm for pleiotropy. Journal of Physiology. ISSN 0022-3751 doi: https://doi.org/10.1113/JP276163

Mascal, M., Hafezi, N., Wang, D., Hu, Y., Serra, G., Dallas, M. L. ORCID: https://orcid.org/0000-0002-5190-0522 and Spencer, J. P. E. ORCID: https://orcid.org/0000-0003-2931-7274 (2019) Synthetic, non-intoxicating 8,9-dihydrocannabidiol for the mitigation of seizures. Scientific Reports, 9 (1). 7778. ISSN 2045-2322 doi: https://doi.org/10.1038/s41598-019-44056-y

Mitchell, R., Mellows, B., Sheard, J., Antonioli, M., Kretz, O., Chambers, D., Zeuner, M.-T., Tomkins, J. E., Denecke, B., Musante, L., Joch, B., Debacq-Chainiaux, F., Holthofer, H., Ray, S., Huber, T. B., Dengjel, J., De Coppi, P., Widera, D. ORCID: https://orcid.org/0000-0003-1686-130X and Patel, K. (2019) Secretome of adipose-derived mesenchymal stem cells promotes skeletal muscle regeneration through synergistic action of extracellular vesicle cargo and soluble proteins. Stem Cell Research and Therapy, 10. 116. ISSN 1757-6512 doi: https://doi.org/10.1186/s13287-019-1213-1

Patra, P. H., Barker-Haliski, M., White, H. S., Whalley, B. J., Glyn, S., Sandhu, H., Jones, N., Bazelot, M., Williams, C. M. ORCID: https://orcid.org/0000-0003-4452-671X and McNeish, A. J. (2019) Cannabidiol reduces seizures and associated behavioral comorbidities in a range of animal seizure and epilepsy models. Epilepsia, 60 (2). ISSN 0013-9580 doi: https://doi.org/10.1111/epi.14629

Ravishankar, D., Albadawi, D., Chaggar, V., Patra, P., Williams, H., Salamah, M., Vaiyapuri, R., Dash, P., Patel, K., Watson, K. ORCID: https://orcid.org/0000-0002-9987-8539 and Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517 (2019) Isorhapontigenin, a resveratrol analogue selectively inhibits ADP-stimulated platelet activation. European Journal of Pharmacology, 862. 172627. ISSN 0014-2999 doi: https://doi.org/10.1016/j.ejphar.2019.172627

Ridzuan, R., Widera, D. ORCID: https://orcid.org/0000-0003-1686-130X and Yahaya, B. H. (2019) Secretome of mesenchymal stem cells and its impact on Chronic Obstructive Pulmonary Disease. In: Pham, P. V. (ed.) Stem Cell Transplantation for Autoimmune Diseases and Inflammation. Stem Cells in Clinical Applications. Springer, pp. 139-157. ISBN 978-3-030-23420-1 doi: https://doi.org/10.1007/978-3-030-23421-8_8

Salamah, M. F., Ravishankar, D., Vaiyapuri, R., Moraes, L. A., Patel, K., Perretti, M., Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 and Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517 (2019) The formyl peptide fMLF primes platelet activation and augments thrombus formation. Journal of Thrombosis and Haemostasis, 17 (7). pp. 1120-1133. ISSN 1538-7836 doi: https://doi.org/10.1111/jth.14466

Serra, I., Scheldeman, C., Bazelot, M., Whalley, B. J., Dallas, M. L. ORCID: https://orcid.org/0000-0002-5190-0522, De Witte, P. A. M. and Williams, C. M. ORCID: https://orcid.org/0000-0003-4452-671X (2019) Cannabidiol modulates phosphorylated rpS6 signalling in a zebrafish model of tuberous sclerosis complex. Behavioural Brain Research, 363. pp. 135-144. ISSN 0166-4328 doi: https://doi.org/10.1016/j.bbr.2019.01.040

Sheard, J. J., Bicer, M., Meng, Y., Frigo, A., Martinez Aguilar, R., Vallance, T. M., Iandolo, D. and Widera, D. ORCID: https://orcid.org/0000-0003-1686-130X (2019) Optically transparent anionic nanofibrillar cellulose is cytocompatible with human adipose tissue-derived stem cells and allows simple imaging in 3D. Stem Cells International, 2019. 3106929. ISSN 1687-966X doi: https://doi.org/10.1155/2019/3106929

Stephen, T.-L., Tamagnini, F. ORCID: https://orcid.org/0000-0002-8741-5094, Piegsa, J., Sung, K., Harvey, J., Oliver-Evans, A., Murray, T. K., Ahmed, Z., Hutton, M. L., Randall, A., O' Neill, M. J. and Jackson, J. S. (2019) Imbalance in the response of pre- and post-synaptic components to amyloidopathy. Scientific Reports, 9. 14837. ISSN 2045-2322 doi: https://doi.org/10.1038/s41598-019-50781-1

Stephens, G. J. ORCID: https://orcid.org/0000-0002-8966-4238 and Cottrell, G. S. ORCID: https://orcid.org/0000-0001-9098-7627 (2019) CACHD1: a new activity-modifying protein for voltage-gated calcium channels. Channels, 13 (1). pp. 120-123. ISSN 1933-6969 doi: https://doi.org/10.1080/19336950.2019.1600968

Tabatabaee, S., Baker, D., Selwood, D. L., Whalley, B. J. and Stephens, G. J. ORCID: https://orcid.org/0000-0002-8966-4238 (2019) The Cannabinoid-Like Compound, VSN16R, Acts on Large Conductance, Ca2+-Activated K+ Channels to Modulate Hippocampal CA1 Pyramidal Neuron Firing. Pharmaceuticals, 12 (3). 104. ISSN 1424-8247 doi: https://doi.org/10.3390/ph12030104

Vallance, T. M., Ravishankar, D., Albadawi, D. A. I., Osborn, H. M. I. ORCID: https://orcid.org/0000-0002-0683-0457 and Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517 (2019) Synthetic flavonoids as novel modulators of platelet function and thrombosis. International Journal of Molecular Sciences, 20 (12). e3106. ISSN 1422-0067 doi: https://doi.org/10.3390/ijms20123106

Vallance, T., Ravishankar, D., Albadawi, D., Layfield, H., Sheard, J., Vaiyapuri, R., Dash, P., Patel, K., Widera, D. ORCID: https://orcid.org/0000-0003-1686-130X and Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517 (2019) Effect of ultrapure lipopolysaccharides derived from diverse bacterial species on the modulation of platelet activation. Scientific Reports, 9. 18258. ISSN 2045-2322 doi: https://doi.org/10.1038/s41598-019-54617-w

Wade, J. J., Breslin, K., Wong-Lin, K., Harkin, J., Flanagan, B., Van Zalinge, H., Hall, S., Dallas, M. ORCID: https://orcid.org/0000-0002-5190-0522, Bithell, A., Verkhratsky, A. and McDaid, L. (2019) Calcium microdomain formation at the perisynaptic cradle due to NCX reversal: a computational study. Frontiers in Cellular Neuroscience, 13. 185. ISSN 1662-5102 doi: https://doi.org/10.3389/fncel.2019.00185

Whalley, B. J., Lin, H., Bell, L. ORCID: https://orcid.org/0000-0003-0677-021X, Hill, T., Patel, A., Gray, R. A., Roberts, E., Devinsky, O., Bazelot, M., Williams, C. M. ORCID: https://orcid.org/0000-0003-4452-671X and Stephens, G. J. ORCID: https://orcid.org/0000-0002-8966-4238 (2019) Species-specific susceptibility to cannabis-induced convulsions. British Journal of Pharmacology, 176 (10). pp. 1506-1523. ISSN 0007-1188 doi: https://doi.org/10.1111/bph.14165

Widera, D. ORCID: https://orcid.org/0000-0003-1686-130X, Martinez-Aguilar, R. and Cottrell, G. ORCID: https://orcid.org/0000-0001-9098-7627 (2019) Toll-like 4 and protease-activated receptor 2 in physiology and pathophysiology of the nervous system: more than just receptor cooperation? Neural Regeneration Research, 14 (7). pp. 1196-1201. ISSN 1876-7958 doi: https://doi.org/10.4103/1673-5374.251290

Williams, H. F., Layfield, H. J., Vallance, T., Patel, K., Bicknell, A. B., Trim, S. A. and Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517 (2019) The urgent need to develop novel strategies for the diagnosis and treatment of snakebites. Toxins, 11 (6). 363. ISSN 2072-6651 doi: https://doi.org/10.3390/toxins11060363

Williams, H., Mellows, B., Mitchell, R., Sfyri, P., Layfield, H., Salamah, M., Vaiyapuri, R., Collins-Hooper, H., Bicknell, A., Matsakas, A., Patel, K. and Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517 (2019) Mechanisms underpinning the permanent muscle damage induced by snake venom metalloprotease. PLoS Neglected Tropical Diseases, 13 (1). e0007041. ISSN 1935-2735 doi: https://doi.org/10.1371/journal.pntd.0007041

2018

Arjmand, S. , Behzadi, M., Stephens, G. J. ORCID: https://orcid.org/0000-0002-8966-4238, Ezzatabadipou, S. , Seifaddini, R. , Arjmand, S. and Shabani, M. (2018) A brain on a roller coaster: can the dopamine reward system act as a protagonist to subdue the ups and downs of bipolar disorder? The Neuroscientist, 24 (5). pp. 423-439. ISSN 1073-8584 doi: https://doi.org/10.1177/1073858417714226

Barrese, V., Stott, J. B., Figueiredo, H. B., Aubdool, A. A., Hobbs, A. J., Jepps, T. A., McNeish, A. and Greenwood, I. A. (2018) Angiotensin II promotes KV7.4 channels degradation through reduced interaction with HSP90 (heat shock protein 90). Hypertension, 71 (6). pp. 1091-1100. ISSN 1524-4563 doi: https://doi.org/10.1161/HYPERTENSIONAHA.118.11116

Bell, D. C. and Dallas, M. ORCID: https://orcid.org/0000-0002-5190-0522 (2018) Using automated patch clamp electrophysiology platforms in pain-related ion channel research: insights from industry and academia. British Journal of Pharmacology, 175 (12). pp. 2312-2321. ISSN 1476-5381 doi: https://doi.org/10.1111/bph.13916

Centeno, E. G. Z., Cimarosti, H. and Bithell, A. (2018) 2D versus 3D human induced pluripotent stem cell-derived cultures for neurodegenerative disease modelling. Molecular Neurodegeneration, 13 (1). 27. ISSN 1750-1326 doi: https://doi.org/10.1186/s13024-018-0258-4

Cottrell, G. S. ORCID: https://orcid.org/0000-0001-9098-7627 (2018) CGRP receptor signalling pathways. In: Handbook of Experimental Pharmacology. Springer. doi: https://doi.org/10.1007/164_2018_130

Cottrell, G. S. ORCID: https://orcid.org/0000-0001-9098-7627, Soubrane, C. H., Hounshell, J. A., Lin, H., Owenson, V., Rigby, M., Cox, P. J., Barker, B. S., Ottolini, M., Ince, S., Bauer, C. C., Perez-Reyes, E., Patel, M. K., Stevens, E. B. and Stephens, G. J. ORCID: https://orcid.org/0000-0002-8966-4238 (2018) CACHD1 is an α2δ-like protein that modulates CaV3 voltage-gated calcium channel activity. The Journal of Neuroscience, 38 (4). pp. 9186-9201. ISSN 1529-2401 doi: https://doi.org/10.1523/JNEUROSCI.3572-15.2018

Ferrari, R., Kia, D. A., Tomkins, J. E., Hardy, J., Wood, N. W., Lovering, R. C., Lewis, P. A. and Manzoni, C. (2018) Stratification of candidate genes for Parkinson’s disease using weighted protein interaction network analysis. BMC Genomics, 19. 452. ISSN 1471-2164 doi: https://doi.org/10.1186/s12864-018-4804-9

Giacomina, R., Redaelli, V., Contiero, P., Fabiano, S., Tagliabue, G., Perego, P., Benussi, L., Bruni, A., Filippini, G., Farinotti, M., Giaccone, G., Buitatiotis, S., Manzoni, C., Ferrari, R. and Tagliavini, F. (2018) Tau mutations serve as a novel risk factor for cancer. Cancer Research, 78 (13). pp. 3731-3739. ISSN 0008-5472 doi: https://doi.org/10.1158/0008-5472.CAN-17-3175

Hackl, E., Darkwah, J., Smith, G. and Ermolina, I. (2018) Effect of arginine on the aggregation of protein in freeze-dried Formulations containing sugars and polyol: 1-formulation development. AAPS PharmSciTech, 19 (2). pp. 896-911. ISSN 1530-9932 doi: https://doi.org/10.1208/s12249-017-0884-0

Hackl, E., Darkwah, J., Smith, G. and Ermolina, I. (2018) Effect of arginine on the aggregation of protein in freeze-dried formulations containing sugars and polyol: II. BSA reconstitution and aggregation. AAPS PharmSciTech, 19 (7). pp. 2934-2947. ISSN 1530-9932 doi: https://doi.org/10.1208/s12249-018-1114-0

Hartlova, A., Herbst, S., Peltier, J., Rodgers, A., Bilkei-Gorzo, O., Fearns, A., Dill, B. D., Lee, H., Rowan, F., Cowley, S. A., Davies, P., Lewis, P. A., Ganley, I. G., Martinez, J., Alessi, D. R., Reith, A. D., Trost, M. and Gutierrez, M. G. (2018) LRRK2 is a negative regulator of Mycobacterium tuberculosis phagosome maturation in macrophages. The EMBO Journal, 37 (12). e98694. ISSN 0261-4189 doi: https://doi.org/10.15252/embj.201798694

Jammal, L., Whalley, B. and Barkai, E. (2018) Learning-induced modulation of the effect of neuroglial transmission onsynaptic plasticity. Journal of Neurophysiology, 119 (6). pp. 2373-2379. ISSN 0022-3077 doi: https://doi.org/10.1152/jn.00101.2018

Limbu, R., Cottrell, G. S. ORCID: https://orcid.org/0000-0001-9098-7627 and McNeish, A. J. (2018) Characterisation of the vasodilation effects of DHA and EPA, n-3 PUFAs (fish oils), in rat aorta and mesenteric resistance arteries. PLoS ONE, 13 (2). e0192484. ISSN 1932-6203 doi: https://doi.org/10.1371/journal.pone.0192484

Maiarù, M. ORCID: https://orcid.org/0000-0003-0927-6567, Leese, C., Certo, M., Echeverria-Altuna, I., Mangione, A. S., Arsenault, J., Davletov, B. and Hunt, S. P. (2018) Selective neuronal silencing using synthetic botulinum molecules alleviates chronic pain in mice. Science Translational Medicine, 10 (450). eaar7384. ISSN 1946-6234 doi: https://doi.org/10.1126/scitranslmed.aar7384

Maiarù, M. ORCID: https://orcid.org/0000-0003-0927-6567, Morgan, O. B., Mao, T., Breitsamer, M., Bamber, H., Pöhlmann, M., Schmidt, M. V., Winter, G., Hausch, F. and Géranton, S. M. (2018) The stress regulator FKBP51: a novel and promising druggable target for the treatment of persistent pain states across sexes. Pain, 159 (7). pp. 1224-1234. ISSN 1872-6623 doi: https://doi.org/10.1097/j.pain.0000000000001204

Mamais, A., Manzoni, C., Nazish, I., Arber, C., Sonustun, B., Wray, S., Warner, T. T., Cookson, M. R., Lewis, P. A. and Bandopadhyay, R. (2018) Analysis of macroautophagy related proteins in G2019S LRRK2 Parkinson's disease brains with Lewy body pathology. Brain Research, 1701. pp. 75-84. ISSN 0006-8993 doi: https://doi.org/10.1016/j.brainres.2018.07.023

Manzoni, C., Kia, D. A., Vandrovcova, J., Hardy, J., Wood, N. W., Lewis, P. A. and Ferrari, R. (2018) Genome, transcriptome and proteome: the rise of omics data and their integration in biomedical sciences. Briefings In Bioinformatics, 19 (2). pp. 286-302. ISSN 1467-5463 doi: https://doi.org/10.1093/bib/bbw114

Manzoni, C., Mamais, A., Dihanich, S., Soutar, M. P. M., Plun-Favreau, H., Bandopadhyay, R., Abeti, R., Giunti, P., Hardy, J., Cookson, M. R., Tooze, S. A. and Lewis, P. A. (2018) mTOR independent alteration in ULK1 Ser758 phosphorylation following chronic LRRK2 kinase inhibition. Bioscience Reports, 38 (2). BSR20171669. ISSN 0144-8463 doi: https://doi.org/10.1042/BSR20171669

McQuaid, K., Hall, J. P. ORCID: https://orcid.org/0000-0003-3716-4378, Brazier, J. A. ORCID: https://orcid.org/0000-0002-4952-584X, Cardin, D. J. and Cardin, C. J. ORCID: https://orcid.org/0000-0002-2556-9995 (2018) X-ray crystal structures show DNA stacking advantage of terminal nitrile substitution in Ru-dppz complexes. Chemistry- A European Journal, 24 (59). pp. 15859-15867. ISSN 1521-3765 doi: https://doi.org/10.1002/chem.201803021

Palombo, F., Masia, F., Mattana, S., Tamagnini, F. ORCID: https://orcid.org/0000-0002-8741-5094, Borri, P., Langbein, W. and Fioretto, D. (2018) Hyperspectral analysis applied to micro-Brillouin maps of amyloid-beta plaques in Alzheimer’s disease brains. Analysis, 143 (24). pp. 6095-6102. ISSN 1467-8284 doi: https://doi.org/10.1039/C8AN01291A

Palombo, F., Tamagnini, F. ORCID: https://orcid.org/0000-0002-8741-5094, Jeynes, C., Mattana, S., Swift, I., Nallala, J., Hancock, J., Brown, J. T., Randall, A. D. and Stone, N. (2018) Detection of Aβ plaque-associated astrogliosis in Alzheimer’s disease brain by spectroscopic imaging and immunohistochemistry. Analyst, 143 (4). pp. 850-857. ISSN 0003-2654 doi: https://doi.org/10.1039/c7an01747b

Price, A., Manzoni, C., Cookson, M. R. and Lewis, P. A. (2018) The LRRK2 signalling system. Cell and Tissue Research, 373 (1). pp. 39-50. ISSN 0302-766X doi: https://doi.org/10.1007/s00441-017-2759-9

Ravishankar, D., Salamah, M., Akimbaev, A., Williams, H. F., Albadawi, D. A. I., Vaiyapuri, R., Greco, F., Osborn, H. M. I. ORCID: https://orcid.org/0000-0002-0683-0457 and Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517 (2018) Impact of specific functional groups in flavonoids on the modulation of platelet activation. Scientific Reports, 8. 9528. ISSN 2045-2322 doi: https://doi.org/10.1038/s41598-018-27809-z

Roosterman, D., Meyerhof, W. and Cottrell, G. S. ORCID: https://orcid.org/0000-0001-9098-7627 (2018) Proton transport chains in glucose metabolism: mind the proton. Frontiers in Neuroscience, 12. 404. ISSN 1662-453X doi: https://doi.org/10.3389/fnins.2018.00404

Salamah, M. F., Ravishankar, D., Kodji, X., Moraes, L. A., Williams, H. F., Vallance, T. M., Albadawi, D. A., Vaiyapuri, R., Watson, K. ORCID: https://orcid.org/0000-0002-9987-8539, Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352, Brain, S. D., Perretti, M. and Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517 (2018) The endogenous antimicrobial cathelicidin LL37 induces platelet activation and augments thrombus formation. Blood Advances, 2 (21). pp. 2973-2985. ISSN 2473-9529 doi: https://doi.org/10.1182/bloodadvances.2018021758

Sheard, J., Ramasamy, T. S. and Widera, D. ORCID: https://orcid.org/0000-0003-1686-130X (2018) From fibroblasts to medicinal signalling cells: a paradigm shift in translational stem cell research. Drug Target Review, 2018 (2). pp. 42-44. ISSN 2059-1349

Stevens, E. B. and Stephens, G. J. ORCID: https://orcid.org/0000-0002-8966-4238, eds. (2018) Recent advances in targeting ion channels to treat chronic pain. British Journal of Pharmacology, 175 (12). Wiley, pp. 2133-2137. doi: https://doi.org/10.1111/bph.14215

Tamagnini, F. ORCID: https://orcid.org/0000-0002-8741-5094, Cotton, M., Goodall, O., Harrison, G., Jeynes, C., Palombo, F., Tomkow, J., Tomkow, T. and Wedgwood, K. (2018) ‘Of Mice and Dementia’: A filmed conversation on the use of animals in dementia research. Dementia, 17 (8). pp. 1055-1063. ISSN 1741-2684 doi: https://doi.org/10.1177/1471301218789560

Thei, L., Imm, J., Kaisis, E., Dallas, M. L. ORCID: https://orcid.org/0000-0002-5190-0522 and Dallas, T. L. (2018) Microglia in Alzheimer's disease: a role for ion channels. Frontiers in Neuroscience, 12. 676. ISSN 1662-453X doi: https://doi.org/10.3389/fnins.2018.00676

Thei, L., Rocha-Ferreira, E., Peebles, D., Raivich, G. and Hristova, M. (2018) Extracellular signal-regulated kinase 2 has duality in function between neuronal and astrocyte expression following neonatal hypoxic-ischaemic cerebral injury. The Journal of Physiology, 596 (23). pp. 6043-6062. ISSN 0022-3751 doi: https://doi.org/10.1113/jp275649

Tomkins, J. E., Dihanich, S., Beilina, A., Ferrari, R., Ilacqua, N., Cookson, M. R., Lewis, P. A. and Manzoni, C. (2018) Comparative protein interaction network analysis identifies shared and distinct functions for the human ROCO proteins. Proteomics, 18 (10). 1700444. ISSN 1615-9853 doi: https://doi.org/10.1002/pmic.201700444

Williams, H. F., Hayter, P., Ravishankar, D., Baines, A., Layfield, H. J., Croucher, L., Wark, C., Bicknell, A. B., Trim, S. and Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517 (2018) Impact of Naja nigricollis venom on the production of methaemoglobin. Toxins, 10 (12). 539. ISSN 2072-6651 doi: https://doi.org/10.3390/toxins10120539

Zakaria, N., Yusoff, N. M., Zakaria, Z., Widera, D. ORCID: https://orcid.org/0000-0003-1686-130X and Yahaya, B. H. (2018) Inhibition of NF-κB signalling reduces the stemness characteristics of lung cancer stem cells. Frontiers in Oncology, 8. 166. ISSN 2234-943X doi: https://doi.org/10.3389/fonc.2018.00166

Zeuner, M.-T., Didenko, N. N., Humphries, D., Stergiadis, S. ORCID: https://orcid.org/0000-0002-7293-182X, Morash, T. M., Patel, K., Grimm, W.-D. and Widera, D. ORCID: https://orcid.org/0000-0003-1686-130X (2018) Isolation and characterisation of neural crest-derived stem cells from adult ovine palatal tissue. Frontiers in Cell and Developmental Biology, 6. 39. ISSN 2296-634X doi: https://doi.org/10.3389/fcell.2018.00039

2017

Al-Obaidi, H. ORCID: https://orcid.org/0000-0001-9735-0303, Majumder, M. and Bari, F. (2017) Amorphous and crystalline particulates: challenges and perspectives in drug delivery. Current pharmaceutical design, 23 (3). pp. 350-361. ISSN 1873-4286 doi: https://doi.org/10.2174/1381612822666161107162109

Al-Owais, M. M., Hettiarachchi, N. T., Boyle, J. P., Scragg, J. L., Elies, J., Dallas, M. L. ORCID: https://orcid.org/0000-0002-5190-0522, Lippiat, J., Steele, D. S. and Peers, C. (2017) Multiple mechanisms mediating carbon monoxide inhibition of the voltage-gated K+ channel Kv1.5. Cell Death and Disease, 8. e3163. ISSN 1350-9047 doi: https://doi.org/10.1038/cddis.2017.568

Azoidis, I., Metcalfe, J., Reynolds, J., Keeton, S., Hakki, S. S., Sheard, J. and Widera, D. ORCID: https://orcid.org/0000-0003-1686-130X (2017) Three-dimensional cell culture of human mesenchymal stem cells in nanofibrillar cellulose hydrogels. MRS Communications, 7 (3). pp. 458-465. ISSN 2159-6859 doi: https://doi.org/10.1557/mrc.2017.59

Barker, B. S. , Young , G. T. , Soubrane, C. H., Stephens, G. J. ORCID: https://orcid.org/0000-0002-8966-4238, Stevens, E. B. and Patel , M. K. (2017) Ion channels. In: Conn, P. M. (ed.) Conn's Translational Neuroscience 1st Edition. Elsevier Academic Press, London, pp. 11-43. ISBN 9780128023815 doi: https://doi.org/10.1016/B978-0-12-802381-5.00002-6

Barrese, V., Cidad, P., Yueng, S. Y., Lopez-Lopez, J. R., McNeish, A., Ohya, S., Perez-Garcia, M. T. and Greenwood, I. A. (2017) Proliferative role of Kv11 channels in murine arteries. Frontiers in Physiology, 8. 500. ISSN 1664-042X doi: https://doi.org/10.3389/fphys.2017.00500

Brierley, D. I., Samuels, J., Duncan, M., Whalley, B. J. and Williams, C. M. ORCID: https://orcid.org/0000-0003-4452-671X (2017) A cannabigerol-rich Cannabis sativa extract, devoid of ∆9-tetrahydrocannabinol, elicits hyperphagia in rats. Behavioural Pharmacology, 28 (4). pp. 280-284. ISSN 0955-8810 doi: https://doi.org/10.1097/FBP.0000000000000285

Bruyns-Haylett, M., Luo, J., Bruyns-Haylett, A. J., Harris, S., Boorman, L., Milne, E., Vautrelle, N., Hayashi, Y., Whalley, B. J., Jones, M., Berwick, J., Riera, J. and Zheng, Y. ORCID: https://orcid.org/0000-0001-7472-6427 (2017) The neurogenesis of P1 and N1: a concurrent EEG/LFP study. NeuroImage, 146. pp. 575-588. ISSN 1053-8119 doi: https://doi.org/10.1016/j.neuroimage.2016.09.034

Civiero, L., Cogo, S., Kiekens, A., Morganti, C., Tessari, I., Lobbestael, E., Baekelandt, V., Taymans, J.-M., Chartier-Harlin, M.-C., Franchin, C., Arrigoni, G., Lewis, P. A., Piccoli, G., Bubacco, L., Cookson, M. R., Pinton, P. and Greggio, E. (2017) PAK6 phosphorylates 14-3-3γ to regulate steady state phosphorylation of LRRK2. Frontiers in Molecular Neuroscience, 10. 417. ISSN 1662-5099 doi: https://doi.org/10.3389/fnmol.2017.00417

Coelho-Silva, L., Stephens, G. J. ORCID: https://orcid.org/0000-0002-8966-4238 and Cimarosti, H. (2017) SUMOylation and calcium signalling: potential roles in the brain and beyond. Neuronal Signaling, 1 (3). NS20160010. ISSN 2059-6553 doi: https://doi.org/10.1042/NS20160010

Ferrari, R., Lovering, R. C., Hardy, J., Lewis, P. A. and Manzoni, C. (2017) Weighted protein interaction network analysis of frontotemporal dementia. Journal of Proteome Research, 16 (2). pp. 999-1013. ISSN 1535-3907 doi: https://doi.org/10.1021/acs.jproteome.6b00934

Hettiarachchi, N. T., Boyle, J. P., Dallas, M. ORCID: https://orcid.org/0000-0002-5190-0522, Al-Owais, M. M., Scragg, J. L. and Peers, C. (2017) Heme oxygenase-1 derived carbon monoxide suppresses Aβ1-42 toxicity in astrocytes. Cell Death and Disease, 8 (6). e2884. ISSN 1350-9047 doi: https://doi.org/10.1038/cddis.2017.276

Kardia, E., Zakaria, N., Halim, N. S. S. A., Widera, D. ORCID: https://orcid.org/0000-0003-1686-130X and Yahaya, B. H. (2017) The use of mesenchymal stromal cells in treatment of lung disorders. Regenerative Medicine, 12 (2). pp. 2013-2016. ISSN 1746-076X doi: https://doi.org/10.2217/rme-2016-0112

Krüger, C. L., Zeuner, M.-T., Cottrell, G. S. ORCID: https://orcid.org/0000-0001-9098-7627, Widera, D. ORCID: https://orcid.org/0000-0003-1686-130X and Heilemann, M. (2017) Quantitative single-molecule imaging of TLR4 reveals ligand-specific receptor dimerization. Science Signaling, 10 (503). eaan1308. ISSN 1937-9145 doi: https://doi.org/10.1126/scisignal.aan1308

Manzoni, C. (2017) The LRRK2-macroautophagy axis and its relevance to Parkinson's Disease. Biochemical Society Transactions, 45 (1). pp. 155-162. ISSN 1470-8752 doi: https://doi.org/10.1042/bst20160265

Mattana, S., Caponi, S., Tamagnini, F. ORCID: https://orcid.org/0000-0002-8741-5094, Fioretto, D. and Palombo, F. (2017) Viscoelasticity of amyloid plaques in transgenic mouse brain studied by Brillouin microspectroscopy and correlative Raman analysis. Journal of Innovative Optical Health Sciences, 10 (6). 1742001. ISSN 1793-7205 doi: https://doi.org/10.1142/S1793545817420019

Murthy, M. N., Blauwendraat, C., Guelfi, S., Hardy, J., Lewis, P. A. and Trabzuni, D. (2017) Increased brain expression of GPNMB is associated with genome wide significant risk for Parkinson's disease on chromosome 7p15.3. Neurogenetics, 18 (3). pp. 121-133. ISSN 1364-6745 doi: https://doi.org/10.1007/s10048-017-0514-8

Noyce, A. J., Kia, D. A., Hemani, G., Nicolas, A., Price, T. R., De Pablo-Fernandez, E., Haycock, P. C., Lewis, P. A., Foltynie, T., Davey Smith, G., Schrag, A., Lees, A. J., Hardy, J., Singleton, A., Nalls, M. A., Pearce, N., Lawlor, D. A. and Wood, N. W. (2017) Estimating the causal influence of body mass index on risk of Parkinson disease: a Mendelian randomisation study. PLoS Medicine, 14 (6). e1002314. ISSN 1549-1676 doi: https://doi.org/10.1371/journal.pmed.1002314

Onetti, Y., Dantas, A. Y., Perez, B., McNeish, A. J., Vila, E. and Jimenez-Altyayo, F. (2017) Peroxynitrate formed during a transient episode of brain ischemia increases endothelium-derived hyperpolarization-type dilations in thromboxane/prostaglandin receptor stimulated rat cerebral arteries. Acta Physiologica, 220 (1). pp. 150-166. ISSN 1748-1716 doi: https://doi.org/10.1111/apha.12809

Ravishankar, D., Salamah, M., Attina, A., Pothi, R., Vallance, T. M., Javed, M., Williams, H. F., Alzahrani, E. M. S., Kabova, E., Vaiyapuri, R., Shankland, K. ORCID: https://orcid.org/0000-0001-6566-0155, Gibbins, J. ORCID: https://orcid.org/0000-0002-0372-5352, Strohfeldt, K., Greco, F., Osborn, H. M. I. ORCID: https://orcid.org/0000-0002-0683-0457 and Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517 (2017) Ruthenium-conjugated chrysin analogues modulate platelet activity, thrombus formation and haemostasis with enhanced efficacy. Scientific Reports, 7. 5738. ISSN 2045-2322 doi: https://doi.org/10.1038/s41598-017-05936-3

Rosenberg, E. C., Patra, P. H. and Whalley, B. J. (2017) Therapeutic effects of cannabinoids in animal models of seizures, epilepsy, epileptogenesis, and epilepsy-related neuroprotection. Epilepsy & Behaviour, 70 (Part B). pp. 319-327. ISSN 1525-5050 doi: https://doi.org/10.1016/j.yebeh.2016.11.006

Roux, B. T., Bauer, C. C., McNeish, A. J., Ward, S. G. and Cottrell, G. S. ORCID: https://orcid.org/0000-0001-9098-7627 (2017) The role of ubiquitination and hepatocyte growth factor-regulated tyrosine kinase substrate in the degradation of the adrenomedullin type I receptor. Scientific Reports, 7 (1). p. 12389. ISSN 2045-2322 doi: https://doi.org/10.1038/s41598-017-12585-z

Ryan, K., Team, V. and Alexander, J. (2017) The theory of agency and breastfeeding. Psychology & Health, 32 (3). pp. 312-329. ISSN 1476-8321 doi: https://doi.org/10.1080/08870446.2016.1262369

Scheldeman, C., Mills, J. D., Siekierska, A., Serra, I., Copmans, D., Iyer, A. M., Whalley, B. J., Maes, J., Jansen, A. C., Lagae, L., Aronica, E. and de Witte, P. A. M. (2017) mTOR-related neuropathology in mutant tsc2 zebrafish: Phenotypic, transcriptomic and pharmacological analysis. Neurobiology of disease, 108. pp. 225-237. ISSN 1095-953X doi: https://doi.org/10.1016/j.nbd.2017.09.004

Smith, I., Silveirinha, V., Stein, J. L., de la Torre-Ubieta, L., Farrimond, J. A., Williamson, E. M. and Whalley, B. J. (2017) Human neural stem cell-derived cultures in three- dimensional substrates form spontaneously functional neuronal networks. Journal of Tissue Engineering and Regenerative Medicine, 11 (4). pp. 1022-1033. ISSN 1932-7005 doi: https://doi.org/10.1002/term.2001

Tamagnini, F. ORCID: https://orcid.org/0000-0002-8741-5094, Walsh, D., Brown, J. T., Bondulich, M. K., Hanger, D. P. and Randall, A. D. (2017) Hippocampal neurophysiology is modified by a disease-associated C-terminal fragment of tau protein. Neurobiology of Aging, 60. pp. 44-56. ISSN 0197-4580 doi: https://doi.org/10.1016/j.neurobiolaging.2017.07.005

Turner, S. E., Williams, C. M. ORCID: https://orcid.org/0000-0003-4452-671X, Iversen, L. and Whalley, B. J. (2017) Molecular pharmacology of phytocannabinoids. In: Kinghorn, A. D., Falk, H., Gibbons, S. and Kobayashi, J.'i. (eds.) Phytocannabinoids. Progress in the Chemistry of Organic Natural Products, 103. Springer, pp. 61-101. ISBN 9783319455396 doi: https://doi.org/10.1007/978-3-319-45541-9_3

Ugbode, C. I., Smith, I., Whalley, B. J., Hirst, W. D. and Rattray, M. (2017) Sonic hedgehog signalling mediates astrocyte crosstalk with neurons to confer neuroprotection. Journal of Neurochemistry, 142 (3). pp. 429-443. ISSN 1471-4159 doi: https://doi.org/10.1111/jnc.14064

Ugbode, C., Yuhan, H., Whalley, B., Peers, C., Rattray, M. and Dallas, M. L. ORCID: https://orcid.org/0000-0002-5190-0522 (2017) Astrocytic transporters in Alzheimer's disease. Biochemical Journal, 474 (3). pp. 333-355. ISSN 1470-8728 doi: https://doi.org/10.1042/BCJ20160505

Vallance, T., Zeuner, M.-T., Williams, H., Widera, D. ORCID: https://orcid.org/0000-0003-1686-130X and Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517 (2017) Toll-like receptor 4 signalling and its impact on platelet function, thrombosis, and haemostasis. Mediators of inflammation, 2017. 9605894. ISSN 0962-9351 doi: https://doi.org/10.1155/2017/9605894

Williams, H. F., Vaiyapuri, R., Gajjeraman, P., Hutchinson, G., Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352, Bicknell, A. B. and Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517 (2017) Challenges in diagnosing and treating snakebites in a rural population of Tamil Nadu, India: the views of clinicians. Toxicon, 130. pp. 44-46. ISSN 0041-0101 doi: https://doi.org/10.1016/j.toxicon.2017.02.025

Zeuner, M.-T., Vallance, T., Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517, Cottrell, G. S. ORCID: https://orcid.org/0000-0001-9098-7627 and Widera, D. ORCID: https://orcid.org/0000-0003-1686-130X (2017) Development and characterisation of a novel NF-κB reporter cell line for investigation of neuroinflammation. Mediators of inflammation, 2017. 6209865. ISSN 0962-9351 doi: https://doi.org/10.1155/2017/6209865

2016

Abbassian, H., Esmaeili, P., Tahamtan, M., Aghaei, I., Vaziri, Z., Sheibani, V., Whalley, B. J. and Shabani, M. (2016) Cannabinoid receptor agonism suppresses tremor, cognition disturbances and anxiety-like behaviors in a rat model of essential tremor. Physiology & Behavior, 164 (Part A). pp. 314-320. ISSN 0031-9384 doi: https://doi.org/10.1016/j.physbeh.2016.06.013

Abbassian, H., Whalley, B. J., Sheibani, V. and Shabani, M. (2016) Cannabinoid type 1 receptor antagonism ameliorates harmaline-induced essential tremor in rat. British Journal of Pharmacology, 173 (22). pp. 3196-3207. ISSN 1476-5381 doi: https://doi.org/10.1111/bph.13581

Alsanad, S. M., Howard, R. L. and Williamson, E. M. (2016) An assessment of the impact of herb-drug combinations used by cancer patients. BMC complementary and alternative medicine, 16 (1). PMC5070090. ISSN 1472-6882 doi: https://doi.org/10.1186/s12906-016-1372-x

Bhinge, A., Namboori, S. C., Bithell, A., Soldati, C., Buckley, N. J. and Stanton, L. W. (2016) MiR-375 is essential for human spinal motor neuron development and may be involved in motor neuron degeneration. Stem Cells, 34 (1). pp. 124-134. ISSN 1066-5099 doi: https://doi.org/10.1002/stem.2233

Brierley, D., Samuels, J., Duncan, M., Whalley, B. and Williams, C. ORCID: https://orcid.org/0000-0003-4452-671X (2016) Neuromotor tolerability and behavioural characterisation of cannabidiolic acid, a phytocannabinoid with therapeutic potential for anticipatory nausea. Psychopharmacology, 233 (2). pp. 243-254. ISSN 1432-2072 doi: https://doi.org/10.1007/s00213-015-4100-1

Crescente, M., Pluthero, F. G., Li, L., Lo, R. W., Walsh, T. G., Schenk, M. P., Holbrook, L. M., Loureiro, S. ORCID: https://orcid.org/0009-0000-8886-6893, Ali, M. S., Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517, Falet, H., Jones, I. M. ORCID: https://orcid.org/0000-0002-7738-2516, Poole, A. W., Kahr, W. H. A. and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 (2016) Intracellular trafficking, localization, and mobilization of platelet-borne thiol isomerases. Arteriosclerosis Thrombosis and Vascular Biology, 36 (6). pp. 1164-1173. ISSN 1079-5642 doi: https://doi.org/10.1161/ATVBAHA.116.307461

Heath, F., Newman, A., Clementi, C., Pasut, G., Lin, H., Stephens, G. J. ORCID: https://orcid.org/0000-0002-8966-4238, Whalley, B. J., Osborn, H. M. I. ORCID: https://orcid.org/0000-0002-0683-0457 and Greco, F. (2016) A novel PEG–haloperidol conjugate with a non-degradable linker shows the feasibility of using polymer–drug conjugates in a non-prodrug fashion. Polymer Chemistry, 7 (47). pp. 7204-7210. ISSN 1759-9954 doi: https://doi.org/10.1039/c6py01418f

Hover, S., King, B., Hall, B., Loundras, E.-A., Taqi, H., Daly, J., Dallas, M. ORCID: https://orcid.org/0000-0002-5190-0522, Peers, C., Schnettler, E., McKimmie, C., Kohl, A., Barr, J. N. and Mankouri, J. (2016) Modulation of potassium channels inhibits bunyavirus infection. The Journal of Biological Chemistry, 291 (7). pp. 3411-3422. ISSN 1083-351X doi: https://doi.org/10.1074/jbc.M115.692673

Jammal, L., Whalley, B., Ghosh, S., Lamrecht, R. and Barkai, E. (2016) Physiological expression of olfactory discrimination rule learning balances whole-population modulation and circuit stability in the piriform cortex network. Physiological Reports, 4 (14). e12830. ISSN 2051-817X doi: https://doi.org/10.14814/phy2.12830

Kabova, E. A. (2016) Enhanced structure determination from powder diffraction data via algorithm optimisation and the use of conformational information. PhD thesis, University of Reading.

Kara, E., Tucci, A., Manzoni, C., Lynch, D. S., Elpidorou, M., Bettencourt, C., Chelban, V., Manole, A., Hamed, S., Haridy, N., Federoff, M., Preza, E., Hughes, D., Pittman, A., Jaunmuktane, Z., Brandner, S., Xiromerisiou, G., Wiethoff, S., Schottlaender, L., Proukakis, C., Morris, H., Warner, T., Bhatia, K., Korlipara, P., Singleton, A., Hardy, J., Wood, N., Lewis, P. and Houlden, H. (2016) Genetic and phenotypic characterization of complex hereditary spastic paraplegia. Brain : A Journal of Neurology, 139 (7). pp. 1904-1918. ISSN 1460-2156 doi: https://doi.org/10.1093/brain/aww111

Lubbe, S. J., Escott-Price, V., Gibbs, J. R., Nalls, M. A., Bras, J., Price, T. R., Nicolas, A., Jansen, I. E., Mok, K. Y., Pittman, A. M., Tomkins, J. E., Lewis, P. A., Noyce, A. J., Lesage, S., Sharma, M., Schiff, E. R., Levine, A. P., Brice, A., Gasser, T., Hardy, J., Heutink, P., Wood, N. W., Singleton, A. B., Williams, N. M. and Morris, H. R. (2016) Additional rare variant analysis in Parkinson's Disease cases with and without known pathogenic mutations: evidence for oligogenic inheritance. Human Molecular Genetics, 25 (24). pp. 5483-5489. ISSN 1460-2083 doi: https://doi.org/10.1093/hmg/ddw348

Maiarù, M. ORCID: https://orcid.org/0000-0003-0927-6567, Morgan, O. B., Tochiki, K. K., Hobbiger, E. J., Rajani, K., Overington, D. W. U. and Géranton, S. M. (2016) Complex regulation of the regulator of synaptic plasticity histone deacetylase 2 in the rodent dorsal horn after peripheral injury. Journal of Neurochemistry, 138 (2). pp. 222-232. ISSN 0022-3042 doi: https://doi.org/10.1111/jnc.13621

Maiarù, M. ORCID: https://orcid.org/0000-0003-0927-6567, Tochiki, K. K., Cox, M. B., Annan, L. V., Bell, C. G., Feng, X., Hausch, F. and Géranton, S. M. (2016) The stress regulator FKBP51 drives chronic pain by modulating spinal glucocorticoid signaling. Science Translational Medicine, 8 (325). 325ra19. ISSN 1946-6234 doi: https://doi.org/10.1126/scitranslmed.aab3376

Mangione, A. S., Obara, I., Maiarú, M. ORCID: https://orcid.org/0000-0003-0927-6567, Geranton, S. M., Tassorelli, C., Ferrari, E., Leese, C., Davletov, B. and Hunt, S. P. (2016) Nonparalytic botulinum molecules for the control of pain. Pain, 157 (5). pp. 1045-1055. ISSN 0304-3959 doi: https://doi.org/10.1097/j.pain.0000000000000478

Manzoni, C., Mamais, A., Roosen, D. A., Dihanich, S., Soutar, M. P. M., Plun-Favreau, H., Bandopadhyay, R., Hardy, J., Tooze, S. A., Cookson, M. R. and Lewis, P. A. (2016) mTOR independent regulation of macroautophagy by Leucine Rich Repeat Kinase 2 via Beclin-1. Scientific Reports, 6. 35106. ISSN 2045-2322 doi: https://doi.org/10.1038/srep35106

Michelucci, A., Bithell, A., Burney, M. J., Johnston, C. E., Wong, K.-Y., Teng, S.-W., Desai, J., Gumbleton, N., Anderson, G., Stanton, L. W., Williams, B. P. and Buckley, N. J. (2016) The neurogenic potential of astrocytes is regulated by inflammatory signals. Molecular Neurobiology, 53 (6). pp. 3724-3739. ISSN 1559-1182 doi: https://doi.org/10.1007/s12035-015-9296-x

Modebadze, T., Morgan, N. H., Peres, I. A. A., Hadid, R. D., Amada, N., Hill, C., Williams, C. ORCID: https://orcid.org/0000-0003-4452-671X, Stanford, I. M., Morris, C. M., Jones, R. S. G., Whalley, B. J. and Woodhall, G. L. (2016) A low mortality, high morbidity reduced intensity status epilepticus (RISE) model of epilepsy and epileptogenesis in the rat. PLoS ONE, 11 (2). e0147265. ISSN 1932-6203 doi: https://doi.org/10.1371/journal.pone.0147265

Moraes, L. A., Unsworth, A. J., Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517, Ali, M. S., Sasikumar, P., Sage, T., Flora, G. D., Bye, A. P. ORCID: https://orcid.org/0000-0002-2061-2253, Kriek, N., Dorchies, E., Molendi-Coste, O., Dombrowicz, D., Staels, B., Bishop-Bailey, D. and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 (2016) Farnesoid X Receptor and its ligands inhibit the function of platelets. Arteriosclerosis Thrombosis and Vascular Biology, 36 (12). pp. 2324-2333. ISSN 1524-4636 doi: https://doi.org/10.1161/ATVBAHA.116.308093

Müller, J., Greiner, J. F. W., Zeuner, M., Brotzmann, V., Schäfermann, J., Wieters, F., Widera, D. ORCID: https://orcid.org/0000-0003-1686-130X, Sudhoff, H., Kaltschmidt, B. and Kaltschmidt, C. (2016) 1,8-cineol potentiates IRF3-mediated antiviral response in human stem cells and an ex vivo model of rhinosinusitis. Clinical Science. ISSN 0143-5221 doi: https://doi.org/10.1042/CS20160218

Newton, C. L., Wood, M. D. and Strange, P. G. (2016) Examining the effects of sodium ions on the binding of antagonists to dopamine D2 and D3 receptors. PLoS ONE, 11 (7). e0158808. ISSN 1932-6203 doi: https://doi.org/10.1371/journal.pone.0158808

Stephens, G. J. ORCID: https://orcid.org/0000-0002-8966-4238 (2016) Cerebellar circuits: biochemistry, neurotransmitters and neuromodulators: cannabinoids as modulators in the cerebellum. In: Gruol, D. L., Koibuchi, N., Manto, M., Molinari, M., Schmahmann, J. D. and Shen, Y. (eds.) Essentials of Cerebellum and Cerebellar Disorders: A Primer For Graduate Students. Springer, Dordrecht, pp. 255-259. ISBN 9783319245492 doi: https://doi.org/10.1007/978-3-319-24551-5_33

Stephens, G. J. ORCID: https://orcid.org/0000-0002-8966-4238 (2016) Does modulation of the endocannabinoid system have potential therapeutic utility in cerebellar ataxia? Journal of Physiology, 594 (16). pp. 4631-4641. ISSN 1469-7793 doi: https://doi.org/10.1113/JP271106

Tochiki, K. K., Maiarú, M. ORCID: https://orcid.org/0000-0003-0927-6567, Norris, C., Hunt, S. P. and Géranton, S. M. (2016) The mitogen and stress-activated protein kinase 1 regulates the rapid epigenetic tagging of dorsal horn neurons and nocifensive behaviour. Pain, 157 (11). pp. 2594-2604. ISSN 0304-3959 doi: https://doi.org/10.1097/j.pain.0000000000000679

Widera, D. ORCID: https://orcid.org/0000-0003-1686-130X, Klenke, C., Nair, D., Heidbreder, M., Malkusch, S., Sibarita, J.-B., Choquet, D., Kaltschmidt, B., Heilemann, M. and Kaltschmidt, C. (2016) Single-particle tracking uncovers dynamics of glutamate-induced retrograde transport of NF-κB p65 in living neurons. Neurophotonics, 3 (4). 041804. ISSN 2329-4248 doi: https://doi.org/10.1117/1.NPh.3.4.041804

Zeuner, M.-T., Krueger, C. L., Volk, K., Bieback, K., Cottrell, G. S. ORCID: https://orcid.org/0000-0001-9098-7627, Heilemann, M. and Widera, D. ORCID: https://orcid.org/0000-0003-1686-130X (2016) Biased signalling is an essential feature of TLR4 in glioma cells. Biochimica Et Biophysica Acta (BBA) - Molecular Cell Research, 1863 (12). pp. 3084-3095. ISSN 0167-4889 doi: https://doi.org/10.1016/j.bbamcr.2016.09.016

Zeuner, M.-T., Patel, K., Denecke, B., Giebel, B. and Widera, D. ORCID: https://orcid.org/0000-0003-1686-130X (2016) Paracrine effects of TLR4-polarised mesenchymal stromal cells are mediated by extracellular vesicles. Journal of Translational Medicine, 14. 34. ISSN 1479-5876 doi: https://doi.org/10.1186/s12967-016-0794-z

de Carvalho, C., Hoeller, A., Franco, P., Martini, A., Soares, F., Lin, K., Prediger, R., Whalley, B. and Walz, R. (2016) The cannabinoid CB2 receptor-specific agonist AM1241 increases pentylenetetrazole-induced seizure severity in Wistar rats. Epilepsy Research, 127. pp. 160-167. ISSN 0920-1211 doi: https://doi.org/10.1016/j.eplepsyres.2016.08.011

2015

Arjmand, S., Vaziri, Z., Behzadi, M., Abbassian, H., Stephens, G. J. ORCID: https://orcid.org/0000-0002-8966-4238 and Shabani, M. (2015) Cannabinoids and tremor induced by motor-related disorders: friend or foe? Neurotherapeutics, 12 (4). pp. 778-787. ISSN 1933-7213 doi: https://doi.org/10.1007/s13311-015-0367-5

Berliocchi, L., Maiarù, M. ORCID: https://orcid.org/0000-0003-0927-6567, Varano, G. P., Russo, R., Corasaniti, M. T., Bagetta, G. and Tassorelli, C. (2015) Spinal autophagy is differently modulated in distinct mouse models of neuropathic pain. Molecular Pain, 11. 3. ISSN 1744-8069 doi: https://doi.org/10.1186/1744-8069-11-3

Bye, A. P. ORCID: https://orcid.org/0000-0002-2061-2253, Unsworth, A. J., Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517, Stainer, A. R., Fry, M. J. and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 (2015) Ibrutinib inhibits platelet integrin αIIbβ3 outside-in signaling and thrombus stability but not adhesion to collagen. Arteriosclerosis Thrombosis and Vascular Biology, 35 (11). pp. 2326-2335. ISSN 1524-4636 doi: https://doi.org/10.1161/ATVBAHA.115.306130

Civiero, L., Cirnaru, M. D., Beilina, A., Rodella, U., Russo, I., Belluzzi, E., Lobbestael, E., Reyniers, L., Hondhamuni, G., Lewis, P. A., Van den Haute, C., Baekelandt, V., Bandopadhyay, R., Bubacco, L., Piccoli, G., Cookson, M. R., Taymans, J.-M. and Greggio, E. (2015) Leucine-rich repeat kinase 2 interacts with p21-activated kinase 6 to control neurite complexity in mammalian brain. Journal of Neurochemistry, 135 (6). pp. 1242-1256. ISSN 0022-3042 doi: https://doi.org/10.1111/jnc.13369

Duckles, H., Boycott, H. E., Al-Owais, M. M., Elies, J., Johnson, E., Dallas, M. L. ORCID: https://orcid.org/0000-0002-5190-0522, Porter, K. E., Giuntini, F., Boyle, J. P., Scragg, J. L. and Peers, C. (2015) Heme oxygenase-1 regulates cell proliferation via carbon monoxide-mediated inhibition of T-type Ca2+ channels. Pflugers Archive: European Journal of Physiology, 467 (2). pp. 415-427. ISSN 1432-2013 doi: https://doi.org/10.1007/s00424-014-1503-5

Grimm, W.-D., Giesenhagen, B., Hakki, S., Schau, I., Sirak, S., Sletov, A., Varga, G., Vukovic, M. A. and Widera, D. ORCID: https://orcid.org/0000-0003-1686-130X (2015) Translational research and therapeutic applications of neural crest-derived stem cells in regenerative periodontology. Current Oral Health Reports, 2 (4). pp. 266-274. ISSN 2196-3002 doi: https://doi.org/10.1007/s40496-015-0067-6

Ibeas Bih, C., Chen, T., Nunn, A. V. W., Bazelot, M., Dallas, M. ORCID: https://orcid.org/0000-0002-5190-0522 and Whalley, B. J. (2015) Molecular targets of cannabidiol in neurological disorders. Neurotherapeutics, 12 (4). pp. 699-730. ISSN 1933-7213 doi: https://doi.org/10.1007/s13311-015-0377-3

Karttunen, S., Duffield, M., Scrimgeour, N. R., Squires, L., Lim, W. L., Dallas, M. L. ORCID: https://orcid.org/0000-0002-5190-0522, Scragg, J. L., Chicher, J., Dave, K. A., Whitelaw, M. L., Peers, C., Gorman, J. J., Gleadle, J. M., Rychkov, G. Y. and Peet, D. J. (2015) Oxygen-dependent hydroxylation by Factor Inhibiting HIF (FIH) regulates the TRPV3 ion channel. Journal of Cell Science, 128 (2). pp. 225-231. ISSN 0021-9533 doi: https://doi.org/10.1242/jcs.158451

Kiely, A., Ling, H., Asi, Y., Kara, E., Proukakis, C., Schapira, A., Morris, H., Roberts, H., Lubbe, S., Limousin, P., Lewis, P., Lees, A., Quinn, N., Hardy, J., Love, S., Revesz, T., Houlden, H. and Holton, J. (2015) Distinct clinical and neuropathological features of G51D SNCA mutation cases compared with SNCA duplication and H50Q mutation. Molecular Neurodegeneration, 10 (1). 41. ISSN 1750-1326 doi: https://doi.org/10.1186/s13024-015-0038-3

Manzoni, C., Denny, P., Lovering, R. C. and Lewis, P. A. (2015) Computational analysis of the LRRK2 interactome. PeerJ, 3. 778. ISSN 2167-8359 doi: https://doi.org/10.7717/peerj.778

Mehrban, N., Zhu, B., Tamagnini, F. ORCID: https://orcid.org/0000-0002-8741-5094, Young, F. I., Wasmuth, A., Hudson, K. L., Thomson, A. R., Birchall, M. A., Randall, A. D., Song, B. and Woolfson, D. N. (2015) Functionalized α-helical peptide hydrogels for neural tissue engineering. ACS Biomaterials Science & Engineering, 1 (6). pp. 431-439. ISSN 2373-9878 doi: https://doi.org/10.1021/acsbiomaterials.5b00051

Müller, J., Ossig, C., Greiner, J. F. W., Hauser, S., Fauser, M., Widera, D. ORCID: https://orcid.org/0000-0003-1686-130X, Kaltschmidt, C., Storch, A. and Kaltschmidt, B. (2015) Intrastriatal transplantation of adult human neural crest-derived stem cells improves functional outcome in parkinsonian rats. Stem cells translational medicine, 4 (1). pp. 31-43. ISSN 2157-6564 doi: https://doi.org/10.5966/sctm.2014-0078

Nistor, P. A., May, P. W., Tamagnini, F. ORCID: https://orcid.org/0000-0002-8741-5094, Randall, A. D. and Caldwell, M. A. (2015) Long-term culture of pluripotent stem-cell-derived human neurons on diamond – a substrate for neurodegeneration research and therapy. Biomaterial, 61. pp. 139-149. ISSN 0142-9612 doi: https://doi.org/10.1016/j.biomaterials.2015.04.050

Peers, C., Boyle, J. P., Scragg, J. L., Dallas, M. ORCID: https://orcid.org/0000-0002-5190-0522, Al-Owais, M. M., Hettiarachichi, N. T., Elies, J., Johnson, E., Gamper, N. and Steele, D. (2015) Diverse mechanisms underlying the regulation of ion channels by carbon monoxide. British Journal of Pharmacology, 172 (6). pp. 1546-1556. ISSN 0007-1188 doi: https://doi.org/10.1111/bph.12760

Raposo, A. A. S. F., Vasconcelos, F. F., Drechsel, D., Marie, C., Johnston, C., Dolle, D., Bithell, A., Gillotin, S., van den Berg, D. L. C., Ettwiller, L., Flicek, P., Crawford, G. E., Parras, C. M., Berninger, B., Buckley, N. J., Guillemot, F. and Castro, D. S. (2015) Ascl1 coordinately regulates gene expression and the chromatin landscape during neurogenesis. Cell reports, 10 (9). pp. 1544-1556. ISSN 2211-1247 doi: https://doi.org/10.1016/j.celrep.2015.02.025

Ronzitti, G., Bucci, G., Stephens, G. ORCID: https://orcid.org/0000-0002-8966-4238 and Chieregatti, E. (2015) Raft-partitioning of calcium channels regulates their function. Channels, 9 (4). pp. 169-170. ISSN 1933-6969 doi: https://doi.org/10.1080/19336950.2015.1063285

Rosenberg, E. C., Tsien, R. W., Whalley, B. J. and Devinsky, O. (2015) Cannabinoids and epilepsy. Neurotherapeutics, 12 (4). pp. 747-768. ISSN 1933-7213 doi: https://doi.org/10.1007/s13311-015-0375-5

Schürmann, M., Frese, N., Beyer, A., Heimann, P., Widera, D. ORCID: https://orcid.org/0000-0003-1686-130X, Mönkemöller, V., Huser, T., Barbara, K., Christian, K. and Armin, G. (2015) Helium ion microscopy visualizes lipid nanodomains in mammalian cells. Small, 11 (43). pp. 5781-5789. ISSN 1613-6810 doi: https://doi.org/10.1002/smll.201501540

Smith, I., Haag, M., Ugbode, C., Tams, D., Rattray, M., Przyborski, S., Bithell, A. and Whalley, B. J. (2015) Neuronal-glial populations form functional networks in a biocompatible 3D scaffold. Neuroscience Letters, 609. pp. 198-202. ISSN 0304-3940 doi: https://doi.org/10.1016/j.neulet.2015.10.044

Soldati, C., Caramanica, P., Burney, M. J., Toselli, C., Bithell, A., Augusti-Tocco, G., Stanton, L. W., Biagioni, S., Buckley, N. J. and Cacci, E. (2015) RE1 silencing transcription factor/neuron-restrictive silencing factor regulates expansion of adult mouse subventricular zone-derived neural stem/progenitor cells in vitro. Journal of Neuroscience Research, 93 (8). pp. 1203-1214. ISSN 1097-4547 doi: https://doi.org/10.1002/jnr.23572

Swioklo, S., Watson, K. A. ORCID: https://orcid.org/0000-0002-9987-8539, Williamson, E. M., Farrimond, J. A., Putnam, S. E. and Bicknell, K. A. ORCID: https://orcid.org/0000-0002-5888-1424 (2015) Defining key structural determinants for the pro-osteogenic activity of flavonoids. Journal of Natural Products, 78 (11). pp. 2598-2608. ISSN 1520-6025 doi: https://doi.org/10.1021/acs.jnatprod.5b00075

Tamagnini, F. ORCID: https://orcid.org/0000-0002-8741-5094, Novelia, J., Kerrigan, T. L., Brown, J. T., Tsaneva-Atanasova, K. and Randall, A. D. (2015) Altered intrinsic excitability of hippocampal CA1 pyramidal neurons in aged PDAPP mice. Frontiers in Cellular Neuroscience, 9. ISSN 1662-5102 doi: https://doi.org/10.3389/fncel.2015.00372

Tamagnini, F. ORCID: https://orcid.org/0000-0002-8741-5094, Scullion, S., Brown, J. T. and Randall, A. D. (2015) Intrinsic excitability changes induced by acute treatment of hippocampal CA1 pyramidal neurons with exogenous amyloid β peptide. Hippocampus, 25 (7). pp. 786-797. ISSN 1050-9631 doi: https://doi.org/10.1002/hipo.22403

Tochiki, K. K., Maiarù, M. ORCID: https://orcid.org/0000-0003-0927-6567, Miller, J. R. C., Hunt, S. P. and Géranton, S. M. (2015) Short-term anesthesia inhibits formalin-induced extracellular signal-regulated kinase (ERK) activation in the rostral anterior cingulate cortex but not in the spinal cord. Molecular Pain, 11. 49. ISSN 1744-8069 doi: https://doi.org/10.1186/s12990-015-0052-z

Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517, Flora, G. D. and Gibbins, J. M. ORCID: https://orcid.org/0000-0002-0372-5352 (2015) Gap junctions and connexin hemichannels in the regulation of haemostasis and thrombosis. Biochemical Society Transactions, 43 (3). pp. 489-494. ISSN 1470-8752 doi: https://doi.org/10.1042/BST20150055

Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517, Roweth, H., Ali, M., Unsworth, A., Stainer, A., Flora, G., Crescente, M., Jones, C. ORCID: https://orcid.org/0000-0001-7537-1509, Moraes, L. and Gibbins, J. ORCID: https://orcid.org/0000-0002-0372-5352 (2015) Pharmacological actions of nobiletin in the modulation of platelet function. British Journal of Pharmacology, 172 (16). pp. 4133-4145. ISSN 0007-1188 doi: https://doi.org/10.1111/bph.13191

Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517, Sunagar, K., Gibbins, J. ORCID: https://orcid.org/0000-0002-0372-5352, Jackson, T. N. W., Reeks, T. and Fry, B. G. (2015) Kallikrein enzymes. In: Fry, B. (ed.) Venomous reptiles and their toxins: evolution, pathophysiology and biodiscovery. Oxford University Press, New York, pp. 267-280. ISBN 9780199309399

Vogl, C., Tanifuji, S., Danis, B., Daniels, V., Foerch, P., Wolff, C., Whalley, B. J., Mochida, S. and Stephens, G. J. ORCID: https://orcid.org/0000-0002-8966-4238 (2015) Synaptic vesicle glycoprotein 2A modulates vesicular release and calcium channel function at peripheral sympathetic synapses. The European Journal of Neuroscience, 41 (4). pp. 398-409. ISSN 0953-816X doi: https://doi.org/10.1111/ejn.12799

Weber, M., Apostolova, G., Widera, D. ORCID: https://orcid.org/0000-0003-1686-130X, Mittelbronn, M., Dechant, G., Kaltschmidt, B. and Rohrer, H. (2015) Alternative generation of CNS neural stem cells and PNS derivatives from neural crest-derived peripheral stem cells. Stem Cells, 33 (2). pp. 574-588. ISSN 1066-5099 doi: https://doi.org/10.1002/stem.1880

Zeuner, M., Bieback, K. and Widera, D. ORCID: https://orcid.org/0000-0003-1686-130X (2015) Controversial role of toll-like receptor 4 in adult stem cells. Stem cell reviews and reports, 11 (4). pp. 621-634. ISSN 1558-6804 doi: https://doi.org/10.1007/s12015-015-9589-5

2014

Civiero, L., Dihanich, S., Lewis, P. A. and Greggio, E. (2014) Genetic, structural, and molecular insights into the function of ras of complex proteins domains. Chemistry and Biology, 21 (7). pp. 809-818. ISSN 1074-5521 doi: https://doi.org/10.1016/j.chembiol.2014.05.010

Dannoura, A., Giraldo, A., Pereira, I., Gibbins, J. ORCID: https://orcid.org/0000-0002-0372-5352, Dash, P., Bicknell, K. ORCID: https://orcid.org/0000-0002-5888-1424 and Brooks, G. (2014) Ibuprofen inhibits migration and proliferation of human coronary artery smooth muscle cells by inducing a differentiated phenotype: role of peroxisome proliferator-activated receptor y. Journal of Pharmacy and Pharmacology, 66 (6). pp. 779-792. ISSN 0022-3573 doi: https://doi.org/10.1111/jphp.12203

Dihanich, S., Civiero, L., Manzoni, C., Mamais, A., Bandopadhyay, R., Greggio, E. and Lewis, P. A. (2014) GTP binding controls complex formation by the human ROCO protein MASL1. FEBS Journal, 281 (1). pp. 261-274. ISSN 1742-464X doi: https://doi.org/10.1111/febs.12593

Elies, J., Dallas, M. L. ORCID: https://orcid.org/0000-0002-5190-0522, Boyle, J. P., Scragg, J. L., Duke, A., Steele, D. S. and Peers, C. (2014) Inhibition of the cardiac Na+ channel Nav1.5 by carbon monoxide. The Journal of Biological Chemistry, 289 (23). pp. 16421-16429. ISSN 1083-351X doi: https://doi.org/10.1074/jbc.M114.569996

Elies, J., Scragg, J. L., Huang, S., Dallas, M. ORCID: https://orcid.org/0000-0002-5190-0522, Huang, D., MacDougall, D., Boyle, J. P., Gamper, N. and Peers, C. (2014) Hydrogen sulfide inhibits Cav3.2 T-type Ca2+ channels. FASEB Journal, 28 (12). pp. 5376-5387. ISSN 0892-6638 doi: https://doi.org/10.1096/fj.14-257113

Fricke, F., Malkusch, S., Wangorsch, G., Greiner, J. F., Kaltschmidt, B., Kaltschmidt, C., Widera, D. ORCID: https://orcid.org/0000-0003-1686-130X, Dandekar, T. and Heilemann, M. (2014) Quantitative single-molecule localization microscopy combined with rule-based modeling reveals ligand-induced TNF-R1 reorganization toward higher-order oligomers. Histochemistry and cell biology, 142 (1). pp. 91-101. ISSN 1432-119X doi: https://doi.org/10.1007/s00418-014-1195-0