Accessibility navigation


Adaptation and speciation: what can F-st tell us?

Beaumont, M. A. (2005) Adaptation and speciation: what can F-st tell us? Trends in Ecology & Evolution, 20 (8). pp. 435-440. ISSN 0169-5347

Full text not archived in this repository.

It is advisable to refer to the publisher's version if you intend to cite from this work. See Guidance on citing.

To link to this item DOI: 10.1016/j.tree.2005.05.017

Abstract/Summary

A useful way of summarizing genetic variability among different populations is through estimates of the inbreeding coefficient, F-st. Several recent studies have tried to use the distribution of estimates of F-st from individual genetic loci to detect the effects of natural selection. However, the promise of this approach has yet to be fully realized owing to the pervasive dogma that this distribution is highly dependent on demographic history. Here, I review recent theoretical results that indicate that the distribution of estimates of F-st is generally expected to be robust to the vagaries of demographic history. I suggest that analyses based on it provide a useful first step for identifying candidate genes that might be under selection, and explore the ways in which this information can be used in ecological and evolutionary studies.

Item Type:Article
Refereed:Yes
Divisions:Faculty of Life Sciences > School of Biological Sciences
ID Code:10276
Uncontrolled Keywords:QUANTITATIVE GENETIC-VARIATION, HIERARCHICAL BAYESIAN MODEL, COD, GADUS-MORHUA, POPULATION-STRUCTURE, NATURAL-SELECTION, GENOME SCANS, CHROMOSOMAL SPECIATION, POSITIVE SELECTION, HUMAN-EVOLUTION, FINITE, NUMBER

University Staff: Request a correction | Centaur Editors: Update this record

Page navigation