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An elevated PSA, which normalizes, does not exclude the presence of prostate cancer

Boddy, J. L., Pike, D. J., Al-Hayek, S., Shaida, N. and Malone, P. R. (2005) An elevated PSA, which normalizes, does not exclude the presence of prostate cancer. Prostate Cancer and Prostatic Diseases, 8 (4). pp. 349-352. ISSN 1365-7852

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To link to this item DOI: 10.1038/sj.pcan.4500819

Abstract/Summary

The purpose of this study was to determine the incidence of prostate cancer in patients who have an elevated referral prostate-specific antigen (PSA), which subsequently falls to within their normal age-specific reference range prior to prostate biopsy. The study demonstrated that of the 160 patients recruited, 21 (13%) had a repeat PSA level which had fallen back to within their normal range. Five of these 21 patients (24%) were diagnosed with prostate cancer following biopsy, two of whom had a benign prostate examination. The study, therefore, demonstrates that normalisation of the PSA level prior to biopsy does not exclude the presence of prostate cancer even when the prostate feels benign.

Item Type:Article
Refereed:Yes
Divisions:Faculty of Life Sciences > School of Biological Sciences
ID Code:10285
Uncontrolled Keywords:prostate-specific antigen, prostate cancer, ANTIGEN LEVELS

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