The Genomic Threading Database: a comprehensive resource for structural annotations of the genomes from key organismsTools McGuffin, L. J., Street, S. A. , Bryson, K. , Sørensen, S.‐A. and Jones, D. T. (2004) The Genomic Threading Database: a comprehensive resource for structural annotations of the genomes from key organisms. Nucleic Acids Research, 32 (S1). D196-D199. ISSN 1362-4962 Full text not archived in this repository. To link to this article DOI: 10.1093/nar/gkh043 Abstract/SummaryCurrently, the Genomic Threading Database (GTD) contains structural assignments for the proteins encoded within the genomes of nine eukaryotes and 101 prokaryotes. Structural annotations are carried out using a modified version of GenTHREADER, a reliable fold recognition method. The Gen THREADER annotation jobs are distributed across multiple clusters of processors using grid technology and the predictions are deposited in a relational database accessible via a web interface at http://bioinf.cs.ucl.ac.uk/GTD. Using this system, up to 84% of proteins encoded within a genome can be confidently assigned to known folds with 72% of the residues aligned. On average in the GTD, 64% of proteins encoded within a genome are confidently assigned to known folds and 58% of the residues are aligned to structures.
Deposit Details Repository Staff Only: item control page |
Tools
Tools