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A flow reactor process for the synthesis of peptides utilizing immobilized reagents, scavengers and catch and release protocols

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Baxendale, I.R., Ley, S.V., Smith, C. and Tranmer, G.K. (2006) A flow reactor process for the synthesis of peptides utilizing immobilized reagents, scavengers and catch and release protocols. Chemical Communications. pp. 4835-4837. ISSN 1359-7345

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To link to this item DOI: 10.1039/b612197g

Abstract/Summary

A general flow process for the multi-step assembly of peptides has been developed and this procedure has been used to successfully construct a series of Boc, Cbz and Fmoc N-protected dipeptides in excellent yields and purities, including an extension of the method to enable the preparation of a tripeptide derivative.

Item Type:Article
Refereed:Yes
Divisions:No Reading authors. Back catalogue items
ID Code:37122
Publisher:The Royal Society of Chemistry
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