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Loss of Dictyostelium HSPC300 causes a scar-like phenotype and loss of SCAR protein.

Pollitt, A. Y. and Insall, R. H. (2009) Loss of Dictyostelium HSPC300 causes a scar-like phenotype and loss of SCAR protein. BMC cell biology, 10. p. 13. ISSN 1471-2121

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Abstract/Summary

HSPC300 is essential for most SCAR complex functions. The phenotype of HSPC300 knockouts is most similar to mutants in scar, not the other members of the SCAR complex, suggesting that HSPC300 acts most directly on SCAR itself.

Item Type:Article
Refereed:Yes
Divisions:Faculty of Life Sciences > School of Biological Sciences > Biomedical Sciences
ID Code:44803

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