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Regulation of focal adhesions by PtdIns(4,5)P2 and PtdIns(3,4,5)P3 in cancer cell migration

Al-Fahad, D. (2018) Regulation of focal adhesions by PtdIns(4,5)P2 and PtdIns(3,4,5)P3 in cancer cell migration. PhD thesis, University of Reading

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Abstract/Summary

Phosphoinositides and their downstream signalling molecules are involved in adhesion, proliferation and invasion. In this study, MDA-MB-231 breast cancer has been used to investigate the possible role of PtdIns(4,5)P2 and PtdIns(3,4,5)P3 in the regulation of FA turnover. Firstly, PtdIns(4,5)P2 and PtdIns(3,4,5)P3 have been visualised by PLC

Item Type:Thesis (PhD)
Thesis Supervisor:Dash, P.
Thesis/Report Department:School of Biological Sciences
Identification Number/DOI:
Divisions:Faculty of Life Sciences > School of Biological Sciences > Biomedical Sciences
ID Code:79997

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