Accessibility navigation


Can high-risk fungicides be used in mixtures without selecting for fungicide resistance?

Mikaberidze, A., McDonald, B. A. and Bonhoeffer, S. (2014) Can high-risk fungicides be used in mixtures without selecting for fungicide resistance? Phytopathology, 104 (4). pp. 324-331. ISSN 1943-7684

[img]
Preview
Text - Accepted Version
· Please see our End User Agreement before downloading.

499kB

It is advisable to refer to the publisher's version if you intend to cite from this work. See Guidance on citing.

To link to this item DOI: 10.1094/PHYTO-07-13-0204-R

Abstract/Summary

Fungicide mixtures produced by the agrochemical industry often contain low-risk fungicides, to which fungal pathogens are fully sensitive, together with high-risk fungicides known to be prone to fungicide resistance. Can these mixtures provide adequate disease control while minimizing the risk for the development of resistance? We present a population dynamics model to address this question. We found that the fitness cost of resistance is a crucial parameter to determine the outcome of competition between the sensitive and resistant pathogen strains and to assess the usefulness of a mixture. If fitness costs are absent, then the use of the high-risk fungicide in a mixture selects for resistance and the fungicide eventually becomes nonfunctional. If there is a cost of resistance, then an optimal ratio of fungicides in the mixture can be found, at which selection for resistance is expected to vanish and the level of disease control can be optimized.

Item Type:Article
Refereed:Yes
Divisions:Faculty of Life Sciences > School of Agriculture, Policy and Development > Biodiversity, Crops and Agroecosystems Division > Crops Research Group
ID Code:86110
Publisher:APS Publications

Downloads

Downloads per month over past year

University Staff: Request a correction | Centaur Editors: Update this record

Page navigation