Gaining acceptability for the Bayesian decision-theoretic approach in dose-escalation studies
Zhou, Y. and Lucini, M. (2005) Gaining acceptability for the Bayesian decision-theoretic approach in dose-escalation studies. Pharmaceutical Statistics, 4 (3). pp. 161-171. ISSN 1539-1612
Full text not archived in this repository.
To link to this article DOI: 10.1002/pst.172
There has recently been increasing demand for better designs to conduct first-into-man dose-escalation studies more efficiently, more accurately and more quickly. The authors look into the Bayesian decision-theoretic approach and use simulation as a tool to investigate the impact of compromises with conventional practice that might make the procedures more acceptable for implementation. Copyright © 2005 John Wiley & Sons, Ltd.
Repository Staff Only: item control page