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The chemokine receptor, CCR5

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Mueller, A. and Strange, P. G. (2004) The chemokine receptor, CCR5. International Journal of Biochemistry & Cell Biology, 36 (1). pp. 35-38. ISSN 1357-2725

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To link to this item DOI: 10.1016/s1357-2725(03)00172-9

Abstract/Summary

The chemokine receptor, CCR5, is a G protein coupled receptor responsible for some of the effects of the chemokines CCL3, CCL4 and CCL5. It is also one of the co-receptors for the entry of human immunodeficiency virus-1 (HIV-1) into cells. Regulation of CCR5 number on cells is, therefore, important for determining the infection rate by HIV-1. (C) 2003 Elsevier Ltd. All rights reserved.

Item Type:Article
Refereed:Yes
Divisions:Life Sciences > School of Biological Sciences
ID Code:10559
Uncontrolled Keywords:chemokine receptors, CCR5, structure, function, drug action, HIV-1, HIV-1 INFECTION, PROGRESSION, SYSTEM, GENE
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