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Are millets more effective in managing hyperlipidaemia and obesity than major cereal staples? A systematic review and meta-analysis

Anitha, S., Tsusaka, T. W., Botha, R., Kane-Potaka, J., Givens, D. I., Rajendran, A. and Bhandari, R. K. (2022) Are millets more effective in managing hyperlipidaemia and obesity than major cereal staples? A systematic review and meta-analysis. Sustainability, 14 (11). 6659. ISSN 2071-1050

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To link to this item DOI: 10.3390/su14116659


Millets are important staples across developing countries in Asia and Africa. A previous systematic review and meta-analysis showed that eating millets significantly controlled hyperlipidaemia and obesity by focusing on a comparison of pre- and post-intervention measurements. This study further provides meta-analysis of the effects of the consumption of millets on hyperlipidaemia and obesity by analysing millets against other staple grains using the difference-in-differences method, where the effects were computed on the Standardised Mean Difference scale. Thus, only studies that included a control group as well as the baseline were included. The results from twelve eligible studies on blood lipid profile show significant (p < 0.05) favourable effects of consuming millets compared to other staples (rice, wheat, and quinoa). Specifically, the effects on total cholesterol, triacylglycerol, and very low-density lipoprotein cholesterol levels were −0.44, −0.29, and −0.41, respectively (p < 0.05), while the effect on the high-density lipoprotein cholesterol level was +0.59 (p < 0.05). In addition, the effects on low-density lipoprotein cholesterol and the body mass index were −0.60 and −0.29, respectively, with p = 0.06 each. While this study strengthens the evidence that the consumption of millets contributes to reducing the risks of hyperlipidaemia, and therefore cardiovascular diseases, more detailed and rigorous studies are recommended.

Item Type:Article
Divisions:Interdisciplinary Research Centres (IDRCs) > Institute for Food, Nutrition and Health (IFNH)
ID Code:110293


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