Accessibility navigation

Adaptive designs for Phase I dose-finding studies

Lists
Tools

Zhou, Y. (2010) Adaptive designs for Phase I dose-finding studies. Fundamental & Clinical Pharmacology, 24 (2). pp. 129-138. ISSN 0767-3981

Full text not archived in this repository.

It is advisable to refer to the publisher's version if you intend to cite from this work. See Guidance on citing.

To link to this item DOI: 10.1111/j.1472-8206.2009.00746.x

Abstract/Summary

Improving methodology for Phase I dose-finding studies is currently of great interest in pharmaceutical and medical research. This article discusses the current atmosphere and attitude towards adaptive designs and focuses on the influence of Bayesian approaches.

Item Type:Article
Refereed:Yes
Divisions:Science > School of Mathematical, Physical and Computational Sciences > Department of Mathematics and Statistics > Applied Statistics
ID Code:17763
Uncontrolled Keywords:adaptive designs; Bayesian approaches; dose-finding studies continual reassessment method; i/ii clinical-trials; Bayesian decision procedures; healthy-volunteers; down designs; escalation; agent; toxicity; efficacy; outcomes
Publisher:Wiley
Altmetric
Deposit Details

University Staff: Request a correction | Centaur Editors: Update this record

Page navigation

See also