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Tagged phosphine reagents to assist reaction work-up by phase-switched scavenging using a modular flow reactor

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Smith, C. ORCID: https://orcid.org/0000-0002-5911-5836, Baxendale, I.R., Tranmer, G.K., Baumann, M., Smith, S.C., Lewthwaite, R.A. and Ley, S.V. (2007) Tagged phosphine reagents to assist reaction work-up by phase-switched scavenging using a modular flow reactor. Organic and Biomolecular Chemistry, 5. pp. 1562-1568. ISSN 1477-0520

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To link to this item DOI: 10.1039/b703033a

Abstract/Summary

The use of three orthogonally tagged phosphine reagents to assist chemical work-up via phase-switch scavenging in conjunction with a modular flow reactor is described. These techniques (acidic, basic and Click chemistry) are used to prepare various amides and tri-substituted guanidines from in situ generated iminophosphoranes.

Item Type:Article
Refereed:Yes
Divisions:No Reading authors. Back catalogue items
ID Code:37116
Publisher:Royal Society of Chemistry
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