Accessibility navigation

An eight-parent multiparent advanced generation inter-cross population for winter-sown wheat: creation, properties, and validation

Mackay, I. J., Bansept-Basler, P., Barber, T., Bentley, A. R., Cockram, J., Gosman, N., Greenland, A. J., Horsnell, R., Howells, R., O'Sullivan, D. M., Rose, G. A. and Howell, P. J. (2014) An eight-parent multiparent advanced generation inter-cross population for winter-sown wheat: creation, properties, and validation. G3, 4 (9). pp. 1603-1610. ISSN 2160-1836

Text (Open Access) - Published Version
· Available under License Creative Commons Attribution.
· Please see our End User Agreement before downloading.


It is advisable to refer to the publisher's version if you intend to cite from this work. See Guidance on citing.

To link to this item DOI: 10.1534/g3.114.012963


MAGIC populations represent one of a new generation of crop genetic mapping resources combining high genetic recombination and diversity. We describe the creation and validation of an eight-parent MAGIC population consisting of 1091 F7 lines of winter-sown wheat (Triticum aestivum L.). Analyses based on genotypes from a 90,000-single nucleotide polymorphism (SNP) array find the population to be well-suited as a platform for fine-mapping quantitative trait loci (QTL) and gene isolation. Patterns of linkage disequilibrium (LD) show the population to be highly recombined; genetic marker diversity among the founders was 74% of that captured in a larger set of 64 wheat varieties, and 54% of SNPs segregating among the 64 lines also segregated among the eight founder lines. In contrast, a commonly used reference bi-parental population had only 54% of the diversity of the 64 varieties with 27% of SNPs segregating. We demonstrate the potential of this MAGIC resource by identifying a highly diagnostic marker for the morphological character "awn presence/absence" and independently validate it in an association-mapping panel. These analyses show this large, diverse, and highly recombined MAGIC population to be a powerful resource for the genetic dissection of target traits in wheat, and it is well-placed to efficiently exploit ongoing advances in phenomics and genomics. Genetic marker and trait data, together with instructions for access to seed, are available at

Item Type:Article
Divisions:Interdisciplinary centres and themes > Centre for Food Security
Life Sciences > School of Agriculture, Policy and Development > Department of Crop Science
ID Code:37795
Uncontrolled Keywords:quantitative genetics genome-wide association scan single nucleotide polymorphism QTL mapping recombinant inbred line (RIL) high-density genotyping Multiparent Advanced Generation Inter-Cross (MAGIC) multiparental populations MPP
Publisher:Genetics Society of America


Downloads per month over past year

University Staff: Request a correction | Centaur Editors: Update this record

Page navigation