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Dendrimers: a new class of nanoscopic containers and delivery devices

Aulenta, F., Hayes, W. and Rannard, S. (2003) Dendrimers: a new class of nanoscopic containers and delivery devices. European Polymer Journal, 39 (9). pp. 1741-1771. ISSN 0014-3057

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To link to this article DOI: 10.1016/s0014-3057(03)00100-9

Abstract/Summary

Dendrimers and hyperbranched polymers are a relatively new class of materials with unique molecular architectures and dimensions in comparison to traditional linear polymers. This review details recent notable advances in the application of these new polymers in terms of the development of new polymeric delivery systems. Although comparatively young, the developing field of hyperbranched drug delivery devices is a rapidly maturing area and the key discoveries in drug-conjugate systems amongst others are highlighted. As a consequence of their ideal hyperbranched architectures, the utilisation of host-guest chemistries in dendrimers has been included within the scope of this review. (C) 2003 Elsevier Ltd. All rights reserved.

Item Type:Article
Refereed:Yes
Divisions:Faculty of Life Sciences > School of Chemistry, Food and Pharmacy > Department of Chemistry
ID Code:10977
Uncontrolled Keywords:dendrimer, hyperbranched polymer, drug delivery devices, host-guest, chemistries, AMPHIPHILIC HYPERBRANCHED POLYGLYCEROLS, STARBURST POLYAMIDOAMINE, DENDRIMERS, POLYESTER DENDRITIC SYSTEMS, NEUTRON-CAPTURE THERAPY, DRUG-DELIVERY, IN-VITRO, MOLECULAR RECOGNITION, CONTROLLED-RELEASE, GLYCOL)-BLOCK-POLY(L-LYSINE) DENDRIMER, UNIMOLECULAR MICELLES

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