Accessibility navigation


Beta-lactoglobulin fibers under capillary flow

Castelletto, V. and Hamley, I.W. (2007) Beta-lactoglobulin fibers under capillary flow. Biomacromolecules, 8 (1). pp. 77-83. ISSN 1525-7797

Full text not archived in this repository.

To link to this article DOI: 10.1021/bm0605917

Abstract/Summary

We describe the capillary flow behavior of gels of beta-lactoglobulin (beta-lg) containing droplets of fibrils and the shear flow alignment of beta-lg fibers in dilute aqueous solutions. Polarized optical microscopy and laser scanning confocal microscopy are used to show that capillary shear flow does not affect the fibril droplet sizes in the beta-lg gels, the system behaving in this respect as a solution of compact colloidal particles under shear flow. Small-angle X-ray scattering (SAXS) on dilute aqueous solutions indicates that the fibers can be initially aligned under capillary shear, but this alignment is lost after 18 min of shear. Transmission electron microscopy experiments on the samples studied by SAXS suggest that the loss of orientation is due to a shear-induced breakup of the swollen fibril network. Dynamic and static light scattering on dilute beta-lg fibril aqueous solutions are used to show that before shear beta-lg fibrils behave as strongly interacting semiflexible polymers, while they behave as weakly interacting rods after 18 min of capillary shear.

Item Type:Article
Refereed:Yes
Divisions:Faculty of Life Sciences > School of Chemistry, Food and Pharmacy > Department of Chemistry
ID Code:11094
Uncontrolled Keywords:HEAT-INDUCED DENATURATION, GLOBULAR-PROTEINS, DYNAMIC SCATTERING, INDUCED GELATION, AMYLOID FIBRILS, SEMIFLEXIBLE POLYMERS, IONIC-STRENGTH, GELS, PH, AGGREGATION

University Staff: Request a correction | Centaur Editors: Update this record

Page navigation