Accessibility navigation


Synthesis of chiral 3,4,5,6-tetrahydro-1,4-thiazin-2-ones (thiamorpholin-2-ones)-novel heterocycles possessing enhanced carbonyl electrophilicity over their oxygen counterparts

Drew, M.G.B., Harwood, L.M. and Yan, R. (2006) Synthesis of chiral 3,4,5,6-tetrahydro-1,4-thiazin-2-ones (thiamorpholin-2-ones)-novel heterocycles possessing enhanced carbonyl electrophilicity over their oxygen counterparts. Synlett (19). pp. 3259-3262. ISSN 0936-5214

Full text not archived in this repository.

It is advisable to refer to the publisher's version if you intend to cite from this work. See Guidance on citing.

To link to this item DOI: 10.1055/s-2006-951548

Abstract/Summary

We report herein the first synthesis of chiral derivatives possessing the 1,4-thiazinone core. As predicted, the thiolactone is more susceptible to nucleophilic attack than the equivalent lactone system.

Item Type:Article
Refereed:Yes
Divisions:Faculty of Life Sciences > School of Chemistry, Food and Pharmacy > Department of Chemistry
ID Code:11212
Uncontrolled Keywords:chiral, 1,4-thiazinone, thiamorpholinone , STABILIZED AZOMETHINE YLIDES, 1,3-DIPOLAR CYCLOADDITIONS, ASYMMETRIC INDUCTION, X-RAY, DERIVATIVES

University Staff: Request a correction | Centaur Editors: Update this record

Page navigation